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Bladder Outlet Obstruction

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Paul Abrams – 1st expert on this subject based on the ideXlab platform

  • noninvasive methods of diagnosing Bladder Outlet Obstruction in men part 2 noninvasive urodynamics and combination of measures
    The Journal of Urology, 2006
    Co-Authors: Mohammed Belal, Paul Abrams

    Abstract:

    Purpose: Many methods have been suggested to diagnose Bladder Outlet Obstruction, as defined by the gold standard of pressure flow studies. Difficulty arises when comparing completely different methods of diagnosing Bladder Outlet Obstruction. A comprehensive review of the literature on the different methods used to diagnose Bladder Outlet Obstruction by noninvasive means was performed with a view to allow such a comparison.Materials and Methods: A MEDLINE search was done of the published literature covering until the end of 2004 on noninvasive methods, including single measure and combinations of measures, to diagnose Bladder Outlet Obstruction. A direct comparison of all of the different methods was made using the sensitivity, specificity, likelihood ratio, and pretest and posttest probability of diagnosing Bladder Outlet Obstruction for each test. For many techniques these values were calculated from the data presented in the article.Results: A multitude of methods has been applied to diagnose Bladder

  • noninvasive methods of diagnosing Bladder Outlet Obstruction in men part 1 nonurodynamic approach
    The Journal of Urology, 2006
    Co-Authors: Mohammed Belal, Paul Abrams

    Abstract:

    Purpose: Many methods have been suggested for diagnosing Bladder Outlet Obstruction, as defined by the gold standard of pressure flow studies. Difficulty arises when comparing completely different methods of diagnosing Bladder Outlet Obstruction. A comprehensive review of the literature of the different methods used to diagnose Bladder Outlet Obstruction by noninvasive means was performed with a view to allow such a comparison.Materials and Methods: A MEDLINE search was done of the published literature covering until the end of 2004 on noninvasive methods used to diagnose Bladder Outlet Obstruction. A direct comparison of all different methods was made using the sensitivity and specificity, positive predictive value and likelihood ratio of each test. For many of the techniques these values were calculated from the data presented in the article.Results: A multitude of methods has been applied to diagnose Bladder Outlet Obstruction. Broadly the methods were divided into nonurodynamic and noninvasive urodyna…

  • relationships between lower urinary tract symptoms and Bladder Outlet Obstruction results from the ics bph study
    Neurourology and Urodynamics, 1998
    Co-Authors: J. J. M. C. H. Rosette, Paul Abrams, W P J Witjes, W Schafer, Jenny L Donovan, T J Peters, Richard J Millard, C Frimodtmoller, P Kalomiris

    Abstract:

    Despite the lack of evidence in the literature for close relationships between lower urinary tract symptoms and Bladder Outlet Obstruction, the majority of urologists rely on symptomatology when selecting patients for prostatic surgery. We investigated the relationships between a wide range of lower urinary tract symptoms from the ICSmale questionnaire and the results of urodynamic pressure and flow studies. We evaluated 933 patients with lower urinary tract symptoms suggestive for Bladder Outlet Obstruction from 12 countries who participated in the ICS-“BPH” study with the ICSmale questionnaire and urodynamic pressure and flow studies. Spearman rank correlation coefficients were obtained between symptoms and measures of Bladder Outlet Obstruction. There was little or no correlation between a wide range of symptoms and the results of free uroflowmetry and pressure and flow studies. From symptoms alone, it is not possible to diagnose Bladder Outlet Obstruction. Pressure and flow studies and symptom profiles measure different aspects of the clinical condition that should be viewed separately in the evaluation and treatment decision of the patient presenting with lower urinary tract symptoms. Neurourol. Urodynam. 17:99–108, 1998. © 1998 Wiley-Liss, Inc.

Michael E. Disanto – 2nd expert on this subject based on the ideXlab platform

  • alteration in expression of myosin isoforms in detrusor smooth muscle following Bladder Outlet Obstruction
    American Journal of Physiology-cell Physiology, 2003
    Co-Authors: Michael E. Disanto, Shaohua Chang, Joseph A. Hypolite, Stephen A. Zderic, Alan J. Wein, Raimund Stein, Yongmu Zheng, Samuel Chacko

    Abstract:

    Partial urinary Bladder Outlet Obstruction (PBOO) in men, secondary to benign prostatic hyperplasia, induces detrusor smooth muscle (DSM) hypertrophy. However, despite DSM hypertrophy, some Bladder

  • enhanced force generation by corpus cavernosum smooth muscle in rabbits with partial Bladder Outlet Obstruction
    The Journal of Urology, 2002
    Co-Authors: Shaohua Chang, Joseph A. Hypolite, Stephen A. Zderic, Alan J. Wein, Samuel Chacko, Michael E. Disanto

    Abstract:

    Purpose: Growing clinical evidence suggests that benign prostatic hyperplasia induced partial Bladder Outlet Obstruction is associated with an increased incidence of erectile dysfunction. We determined whether corpus cavernosum smooth muscle from rabbits with partial Bladder Outlet Obstruction show any molecular or functional differences versus controls.Materials and Methods: Force generation and relaxation of corpus cavernosum smooth muscle 2 weeks after partial Bladder Outlet Obstruction by 125 mM. KCl, phenylephrine and field stimulation were determined. Expression of total smooth muscle myosin and alternatively spliced smooth muscle myosin isoforms were determined by reverse transcriptase-polymerase chain reaction (RT-PCR), quantitative competitive RT-PCR, sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blot analysis. Corpus cavernosum smooth muscle from sections of the penis were analyzed morphologically by immunofluorescence microscopy using antibodies to smooth muscle myosin a…

J. J. M. C. H. Rosette – 3rd expert on this subject based on the ideXlab platform

  • relationships between lower urinary tract symptoms and Bladder Outlet Obstruction results from the ics bph study
    Neurourology and Urodynamics, 1998
    Co-Authors: J. J. M. C. H. Rosette, Paul Abrams, W P J Witjes, W Schafer, Jenny L Donovan, T J Peters, Richard J Millard, C Frimodtmoller, P Kalomiris

    Abstract:

    Despite the lack of evidence in the literature for close relationships between lower urinary tract symptoms and Bladder Outlet Obstruction, the majority of urologists rely on symptomatology when selecting patients for prostatic surgery. We investigated the relationships between a wide range of lower urinary tract symptoms from the ICSmale questionnaire and the results of urodynamic pressure and flow studies. We evaluated 933 patients with lower urinary tract symptoms suggestive for Bladder Outlet Obstruction from 12 countries who participated in the ICS-“BPH” study with the ICSmale questionnaire and urodynamic pressure and flow studies. Spearman rank correlation coefficients were obtained between symptoms and measures of Bladder Outlet Obstruction. There was little or no correlation between a wide range of symptoms and the results of free uroflowmetry and pressure and flow studies. From symptoms alone, it is not possible to diagnose Bladder Outlet Obstruction. Pressure and flow studies and symptom profiles measure different aspects of the clinical condition that should be viewed separately in the evaluation and treatment decision of the patient presenting with lower urinary tract symptoms. Neurourol. Urodynam. 17:99–108, 1998. © 1998 Wiley-Liss, Inc.

  • Is there a correlation between prostate size and BladderOutlet Obstruction?
    World Journal of Urology, 1995
    Co-Authors: P. F. W. M. Rosier, J. J. M. C. H. Rosette

    Abstract:

    This retrospective study was conducted in 521 men with micturition complaints to determine the relationship between prostate size and BladderOutlet Obstruction. Analysis showed a statistically significant correlation between BladderOutlet Obstruction and prostate size. Urodynamic BladderOutlet Obstruction was confirmed in 90% of the patients with a prostate size of more than 80 cm^3. In 32% of the patients with a prostate smaller than 40 cm^3, no urodynamic evidence of BladderOutlet Obstruction was found. There was no correlation between symptom scores (Madsen and I-PSS) and the grade of BladderOutlet Obstruction or prostate size. We conclude that precise determination of the prostate size and urodynamics investigations are important (complementary) parameters in the assessment of elderly men with micturition complaints.