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S Ignacimuthu - One of the best experts on this subject based on the ideXlab platform.

  • consensus of local knowledge on medicinal plants among traditional healers in mayiladumparai block of theni district tamil nadu india
    Journal of Ethnopharmacology, 2011
    Co-Authors: P Pandikumar, Muthiah Chellappandian, S Mutheeswaran, S Ignacimuthu
    Abstract:

    Abstract Aim of the study The role of ethnobotany in drug discovery is huge but there are criticisms over such studies due to their qualitative nature. The present study is aimed at quantitatively abstracting the medicinal plant knowledge of the healers trained in traditional ways, in Mayiladumparai block of Theni District, Tamil Nadu, India. Materials and methods The interviews and field observations were carried out in all the 18 village panchayaths from January to June 2010, consisting of 148 field days. The interviews were conducted with 80 traditional healers, after obtaining prior informed consent. Successive free listing was used to interview the informants. The informant consensus factor ( F ic ) was calculated to estimate the use variability of medicinal plants. Fidelity index and Cultural importance index were also calculated to analyze the data. Results This study recorded the ethno-medicinal usage of 142 ethno-species belonging to 62 families that were used to prepare 504 formulations. Jaundice had the highest F ic value than all the illness categories studied. Phyllanthus spp. was the highly cited medicinal plant to treat jaundice and had high fidelity index value. This was followed by Senna angustifolia and Terminalia chebula as laxatives. The highly cited medicinal plants in each group with high F ic value were Pongamia pinnata (antiseptic), Aerva lanata (antidote and snakebite), Blepharis maderaspatensis (cuts and wounds), Abutilon indicum (hemorrhoids), Ruta graveolens (spiritual medicine), Ocimum tenuiflorum (cough), and Solanum trilobatum (pulmonary ailments). Phyllanthus spp., was the most culturally significant species according to this index, followed by Borassus flebellifer. Conclusion The process of drug discovery has become highly expensive and post-approval and post-marketing withdrawal of drugs is continuing. In such scenario, reverse pharmacology is considered an attractive option. The medicinal plants enumerated in this study with high number of citations and high F ic values for illness categories might give some useful leads for further biomedical research.

Hari Prasad Devkota - One of the best experts on this subject based on the ideXlab platform.

  • genus Blepharis acanthaceae a review of ethnomedicinally used species and their phytochemistry and pharmacological activities
    Journal of Ethnopharmacology, 2021
    Co-Authors: Amina Ibrahim Dirar, Anjana Adhikaridevkota, Ripu M Kunwar, Keshav Raj Paudel, Tarun Belwal, Gaurav Gupta, Dinesh Kumar Chellappan, Philip M Hansbro, Kamal Dua, Hari Prasad Devkota
    Abstract:

    Abstract Ethnopharmacological relevance Blepharis is an Afro-Asiatic genus belonging to the family Acanthaceae. It comprises about 126 species that occur in arid and semi-arid habitats. Some species of Blepharis are used in traditional medicines in different countries mainly for their anti-inflammatory, wound healing activities along with treatment of gastrointestinal disorders and bone fractures. Aim of the review The present review aims to collate and analyze the available data and information on distribution, traditional uses, chemical constituents and pharmacological activities of Blepharis. Methods Scientific information of genus Blepharis was retrieved from the online bibliographic databases such as MEDLINE/PubMed, SciFinder, Web of Science and Google Scholar and secondary resources including books and proceedings. Results Seven species of Blepharis were found to be reported frequently as useful in folklore in African and Asian countries. B. maderaspatensis was found to be widely used in Indian traditional medicines whereas the B. ciliaris and B. edulis were common in folklore of Egypt, Jordan, and Arabia. Active phytochemicals of Blepharis are flavonoids from B. ciliaris, alkaloids from B. sindica, phenolic acid derivatives, and phytosterols, and derivatives of hydroxamic acids from B. edulis resulted in possessing diverse biological properties such as anti-microbial, anti-inflammatory, and anti-cancer. Conclusions Various species of Blepharis were found to be used in traditional medicine systems in African and Asian countries. Few of these species were studied for their bioactive chemical constituents however the activity guided isolation studies are not performed. Similarly, detailed pharmacological studies in animal models to explore their mechanism of action are also not reported. Future studies should focus on these aspects related to the medicinally used species of Blepharis. The detailed and comprehensive comparative analysis presented here gives valuable information of the currently used Blepharis species and pave the way to investigate other useful species of Blepharis pertaining to ethnobotany, phytochemistry and discovery of new drugs.

Praz, Christophe J. - One of the best experts on this subject based on the ideXlab platform.

Amina Ibrahim Dirar - One of the best experts on this subject based on the ideXlab platform.

  • genus Blepharis acanthaceae a review of ethnomedicinally used species and their phytochemistry and pharmacological activities
    Journal of Ethnopharmacology, 2021
    Co-Authors: Amina Ibrahim Dirar, Anjana Adhikaridevkota, Ripu M Kunwar, Keshav Raj Paudel, Tarun Belwal, Gaurav Gupta, Dinesh Kumar Chellappan, Philip M Hansbro, Kamal Dua, Hari Prasad Devkota
    Abstract:

    Abstract Ethnopharmacological relevance Blepharis is an Afro-Asiatic genus belonging to the family Acanthaceae. It comprises about 126 species that occur in arid and semi-arid habitats. Some species of Blepharis are used in traditional medicines in different countries mainly for their anti-inflammatory, wound healing activities along with treatment of gastrointestinal disorders and bone fractures. Aim of the review The present review aims to collate and analyze the available data and information on distribution, traditional uses, chemical constituents and pharmacological activities of Blepharis. Methods Scientific information of genus Blepharis was retrieved from the online bibliographic databases such as MEDLINE/PubMed, SciFinder, Web of Science and Google Scholar and secondary resources including books and proceedings. Results Seven species of Blepharis were found to be reported frequently as useful in folklore in African and Asian countries. B. maderaspatensis was found to be widely used in Indian traditional medicines whereas the B. ciliaris and B. edulis were common in folklore of Egypt, Jordan, and Arabia. Active phytochemicals of Blepharis are flavonoids from B. ciliaris, alkaloids from B. sindica, phenolic acid derivatives, and phytosterols, and derivatives of hydroxamic acids from B. edulis resulted in possessing diverse biological properties such as anti-microbial, anti-inflammatory, and anti-cancer. Conclusions Various species of Blepharis were found to be used in traditional medicine systems in African and Asian countries. Few of these species were studied for their bioactive chemical constituents however the activity guided isolation studies are not performed. Similarly, detailed pharmacological studies in animal models to explore their mechanism of action are also not reported. Future studies should focus on these aspects related to the medicinally used species of Blepharis. The detailed and comprehensive comparative analysis presented here gives valuable information of the currently used Blepharis species and pave the way to investigate other useful species of Blepharis pertaining to ethnobotany, phytochemistry and discovery of new drugs.

  • Genus Blepharis (Acanthaceae): A review of ethnomedicinally used species, and their phytochemistry and pharmacological activities.
    'Elsevier BV', 2020
    Co-Authors: Amina Ibrahim Dirar, Dinesh Kumar Chellappan, Philip M Hansbro, Aa Devkota, Rm Kunwar, Kr Paudel, Belwal T, Gupta G, Dua K, Hp Devkota
    Abstract:

    ETHNOPHARMACOLOGICAL RELEVANCE:Blepharis is an Afro-Asiatic genus belonging to the family Acanthaceae. It comprises 126 species that occur in arid and semi-arid habitats. Some species of Blepharis are used in traditional medicines in different countries mainly for their anti-inflammatory, would healing activities along with treatment of gastrointestinal disorders and bone fractures. AIM OF THE REVIEW:The present review aims to collate and analyze the available data and information on distribution, traditional uses, chemical constituents and pharmacological activities of Blepharis. METHODS:Scientific information of genus Blepharis was retrieved from the online bibliographic databases like MEDLINE/PubMed, SciFinder, Web of Science and Google Scholar and secondary resources including books and proceedings. RESULTS:Seven species of Blepharis were found to be reported frequently as useful in folklore in Asian and African countries. B. maderaspatensis was found to be widely used in Indian traditional medicines whereas the B. ciliaris and B. edulis were common in folklore of Egypt, Jordan, and Arabia. Active phytochemicals of Blepharis are flavonoids from B. ciliaris, alkaloids from B. sindica, phenolic acid derivatives, and phytosterols, and derivatives of hydroxamic acids from B. edulis resulted in possessing diverse biological properties such as anti-microbial, anti-inflammatory, and anti-cancer. CONCLUSION:Various species of Blepharis were found to be used in traditional medicine systems in African and Asian countries. Few of these species were studied for their bioactive chemical constituents however the activity guided isolation studies are not performed. Similarly, detailed pharmacological studies in animal models to explore their mechanism of action are also not reported. Future studies should focus on these aspects related to the medicinally used species of Blepharis. The detailed and comprehensive comparative analysis presented here gives valuable information of the currently used Blepharis species and pave the way to investigate other useful species of Blepharis pertaining to ethnobotany, phytochemistry and discovery of new drugs

F. M. Khan - One of the best experts on this subject based on the ideXlab platform.

  • Ethno-veterinary medicinal usage of flora of greater Cholistan desert
    2015
    Co-Authors: F. M. Khan
    Abstract:

    A study on the ethno-veterinary usage of wild medicinal plants of Greater Cholistan desert of Pakistan was conducted from January, 2007 to December, 2008. Information regarding 35 plant species was collected. According to the results, Blepharis sindica was used as galactagogue. Butea monosperma, Calotropis procera and Phyllanthus nirurii were used as emollient, demulcent and antiphlogistic. Amaranthus trilocular, Capparis decidua, Clerodendron phlomoides, Phyllanthus nirurii and Ricinus communis were used as carminative and stomachic. Capparis decidua and Calotropis procera were used as appetizer. Prosopis glandulosa had anodyne properties, Achyranthes aspera had antilithic, while Pedalium murex, Tribulus terrestris and Barleria prionites had diuretic value. Achyranthes aspera, Argemone mexicana, Balanites aegyptiaca, Butea monosperma, Cassia senna, Citrullus colocynthis and Vitex negundo were used as vermifuge. Alhagi camelorum and Balanites aegyptiaca had aperient properties. Barleria prionites and Mollugo nudicaulis had their role in the ripening of an abscess. Ricinus communis and Salvadora oleoides aided in the removal of placenta and lochia. Anamitra cocculus and Argemone mexicana were used as febrifuge. Aerva javanica, Ailanthus excelsa, Amaranthus trilocular, Capparis decidua were used in diarrhoea and dysentery. Argemone mexicana and Ailanthus excelsa were used in ague

  • Ethno-veterinary medicinal usage of flora of Greater Cholistan desert (Pakistan).
    Pakistan Veterinary Journal, 2009
    Co-Authors: F. M. Khan
    Abstract:

    A study on the ethno-veterinary usage of wild medicinal plants of Greater Cholistan desert of Pakistan was conducted from January, 2007 to December, 2008. Information regarding 35 plant species was collected. According to the results, Blepharis sindica was used as galactagogue. Butea monosperma, Calotropis procera and Phyllanthus nirurii were used as emollient, demulcent and antiphlogistic. Amaranthus trilocular, Capparis decidua, Clerodendron phlomoides, Phyllanthus nirurii and Ricinus communis were used as carminative and stomachic. Capparis decidua and Calotropis procera were used as appetizer. Prosopis glandulosa had anodyne properties, Achyranthes aspera had antilithic, while Pedalium murex, Tribulus terrestris and Barleria prionites had diuretic value. Achyranthes aspera, Argemone mexicana, Balanites aegyptiaca, Butea monosperma, Cassia senna, Citrullus colocynthis and Vitex negundo were used as vermifuge. Alhagi camelorum and Balanites aegyptiaca had aperient properties. Barleria prionites and Mollugo nudicaulis had their role in the ripening of an abscess. Ricinus communis and Salvadora oleoides aided in the removal of placenta and lochia. Anamitra cocculus and Argemone mexicana were used as febrifuge. Aerva javanica, Ailanthus excelsa, Amaranthus trilocular, Capparis decidua were used in diarrhoea and dysentery. Argemone mexicana and Ailanthus excelsa were used in ague.