The Experts below are selected from a list of 300 Experts worldwide ranked by ideXlab platform
Yin X Setoh - One of the best experts on this subject based on the ideXlab platform.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN ) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011 ) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN , including the virulent WNVNSW2011 , in human Blood donor samples. Plasma samples were spiked with four different strains of WNVKUN , as well as a prototype WNV strain, at high, medium, and low viral loads. Spiking was confirmed with real-time reverse transcription-polymerase chain reaction (RT-PCR), before testing with the Procleix WNV transcription-mediated amplification (TMA) Blood Screening assay (Grifols). All WNV strains used were detectable by RT-PCR after being spiked into plasma. Additionally, all viral spiked samples were reactive by WNV TMA. We experimentally demonstrate that a commercially available WNV Blood Screening assay can detect different strains of WNVKUN . Given that WNV can be transfusion transmissible, it is essential to confirm that emergent strains are detectable by existing Blood Screening methods. © 2015 AABB.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:BACKGROUND: West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN, including the virulent WNVNSW2011, in human Blood donor samples.
Helen M Faddy - One of the best experts on this subject based on the ideXlab platform.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN ) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011 ) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN , including the virulent WNVNSW2011 , in human Blood donor samples. Plasma samples were spiked with four different strains of WNVKUN , as well as a prototype WNV strain, at high, medium, and low viral loads. Spiking was confirmed with real-time reverse transcription-polymerase chain reaction (RT-PCR), before testing with the Procleix WNV transcription-mediated amplification (TMA) Blood Screening assay (Grifols). All WNV strains used were detectable by RT-PCR after being spiked into plasma. Additionally, all viral spiked samples were reactive by WNV TMA. We experimentally demonstrate that a commercially available WNV Blood Screening assay can detect different strains of WNVKUN . Given that WNV can be transfusion transmissible, it is essential to confirm that emergent strains are detectable by existing Blood Screening methods. © 2015 AABB.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:BACKGROUND: West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN, including the virulent WNVNSW2011, in human Blood donor samples.
Robert L P Flower - One of the best experts on this subject based on the ideXlab platform.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN ) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011 ) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN , including the virulent WNVNSW2011 , in human Blood donor samples. Plasma samples were spiked with four different strains of WNVKUN , as well as a prototype WNV strain, at high, medium, and low viral loads. Spiking was confirmed with real-time reverse transcription-polymerase chain reaction (RT-PCR), before testing with the Procleix WNV transcription-mediated amplification (TMA) Blood Screening assay (Grifols). All WNV strains used were detectable by RT-PCR after being spiked into plasma. Additionally, all viral spiked samples were reactive by WNV TMA. We experimentally demonstrate that a commercially available WNV Blood Screening assay can detect different strains of WNVKUN . Given that WNV can be transfusion transmissible, it is essential to confirm that emergent strains are detectable by existing Blood Screening methods. © 2015 AABB.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:BACKGROUND: West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN, including the virulent WNVNSW2011, in human Blood donor samples.
Clive R Seed - One of the best experts on this subject based on the ideXlab platform.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN ) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011 ) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN , including the virulent WNVNSW2011 , in human Blood donor samples. Plasma samples were spiked with four different strains of WNVKUN , as well as a prototype WNV strain, at high, medium, and low viral loads. Spiking was confirmed with real-time reverse transcription-polymerase chain reaction (RT-PCR), before testing with the Procleix WNV transcription-mediated amplification (TMA) Blood Screening assay (Grifols). All WNV strains used were detectable by RT-PCR after being spiked into plasma. Additionally, all viral spiked samples were reactive by WNV TMA. We experimentally demonstrate that a commercially available WNV Blood Screening assay can detect different strains of WNVKUN . Given that WNV can be transfusion transmissible, it is essential to confirm that emergent strains are detectable by existing Blood Screening methods. © 2015 AABB.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:BACKGROUND: West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN, including the virulent WNVNSW2011, in human Blood donor samples.
Susan Ismay - One of the best experts on this subject based on the ideXlab platform.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN ) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011 ) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN , including the virulent WNVNSW2011 , in human Blood donor samples. Plasma samples were spiked with four different strains of WNVKUN , as well as a prototype WNV strain, at high, medium, and low viral loads. Spiking was confirmed with real-time reverse transcription-polymerase chain reaction (RT-PCR), before testing with the Procleix WNV transcription-mediated amplification (TMA) Blood Screening assay (Grifols). All WNV strains used were detectable by RT-PCR after being spiked into plasma. Additionally, all viral spiked samples were reactive by WNV TMA. We experimentally demonstrate that a commercially available WNV Blood Screening assay can detect different strains of WNVKUN . Given that WNV can be transfusion transmissible, it is essential to confirm that emergent strains are detectable by existing Blood Screening methods. © 2015 AABB.
-
Detection of emergent strains of West Nile virus with a Blood Screening assay.
Transfusion, 2015Co-Authors: Helen M Faddy, Robert L P Flower, Clive R Seed, Susan Ismay, Edgar Ong, Jeffrey M Linnen, Robin Cory, Jerry A Holmberg, Roy A Hall, Yin X SetohAbstract:BACKGROUND: West Nile virus (WNV) is a threat to transfusion safety. WNV Kunjin strain (WNVKUN) is endemic across parts of Australia; however, human infection is believed to be infrequent and is often associated with relatively minor symptoms. A virulent strain, closely related to WNVKUN (termed WNVNSW2011) was recently identified as the etiologic agent of encephalitis in Australian horses. The aim of this project was to investigate whether a commercially available WNV Blood Screening assay can detect different strains of WNVKUN, including the virulent WNVNSW2011, in human Blood donor samples.