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The Experts below are selected from a list of 312 Experts worldwide ranked by ideXlab platform
Noboru Kosai – 1st expert on this subject based on the ideXlab platform
Open heart surgery without Blood Transfusion for cyanotic congenital cardiac defectsThe Japanese Journal of Thoracic and Cardiovascular Surgery, 1998Co-Authors: Takahiko Sakamoto, Yuzo Nagase, Hiroshi Watanabe, Masao Shibairi, Kazuo Utsumi, Hideyuki Nakano, Noboru KosaiAbstract:
Between November 1994 and January 1997, 42 cases of cyanotic congenital cardiac defects underwent definitive surgery at Matsudo Municipal Hospital. We evaluated 30 cases, each weighing from 7 to 20 kg. The procedures were performed at the age of 9 months to 6 years (mean age—2.4 years). The body weights were 7.7 to 20 kg (mean weight—11.4 kg). The preoperative diagnoses were Tetralogy of Fallot (TOF) in 19 cases, Fontan candidates in 6 and the others in 5. We classified them into 3 groups; Group Abstract—15 cases were completed with non-Blood Transfusion, Group B—8 cases used only plasma protein fraction and Group C—7 cases used Blood Transfusion. Cardiopulmonary bypass (CPB) system is a semi-closed circuit and priming volume is 400 to 600 ml. There is no difference among the 3 groups in operative age, body weight, opeartion time, CPB time, aortic cross clamp time, bleeding and postoperative state. The same results were obtained in minimum base excess and urine output during CPB and the changes of hematocrit and total protein. In Groups A and B, CPB Blood was retruned to the patient as soon as possible after CPB was weaned, but in Group C, Blood Transfusion was performed without the return of CPB Blood. In all groups, hemodynamics were stable. Retrospectively, it is thought that Blood Transfusion was not necessary in Group C and the use of the plamsa protein fraction was not needed in Group B. In conclusion, the open heart surgery can be performed safely without Blood Transfusion for cyanotic congenital cardiac defects.
Andras Treszl – 2nd expert on this subject based on the ideXlab platform
risks and predictors of Blood Transfusion in pediatric patients undergoing open heart operationsThe Annals of Thoracic Surgery, 2009Co-Authors: Andrea Szekely, Zsuzsanna Cserep, Erzsebet Sapi, Tamas Breuer, Csaba A Nagy, Peter Vargha, Istvan Hartyanszky, Andras Szatmari, Andras TreszlAbstract:
Background Blood Transfusion in adults is associated with increased mortality and morbidity after cardiac operations. The aim of this study was to identify the main predictors of Blood Transfusion and explore the relationship between Blood Transfusion and adverse outcomes in a pediatric population. Methods We retrospectively analyzed a prospectively collected database (January 2002 to December 2003) of 657 consecutive pediatric patients undergoing open heart procedures in a tertiary pediatric cardiac center. Risk models were calculated for each Blood product and for the total amount of Blood transfused during the operation and in the first 24 hours. Postoperative adverse events were investigated after propensity score adjustment. Results During the postoperative period, 30 patients (4.6%) died, 80 (12.2%) sustained nonvascular pulmonary complications, and 113 (17.2%) had infection. The risk model for the total amount of Blood Transfusion included weight, preoperative creatinine clearance, preoperative mechanical ventilation, duration of operation and cross-clamp, surgeon, delayed chest closure, inotropic dose, and nitric oxide administration. Univariate analyses demonstrated significant associations between Blood Transfusion and occurrence of every complication except of neurologic events. After adjustment for propensity score and disease severity, the total amount of Blood Transfusion was independently associated with an increased risk for infections (odds ratio, 1.01; 95% confidence interval, 1.002 to 1.02; p = 0.01). Transfusion of platelets was associated with lower incidence of nonvascular pulmonary complications (odds ratio, 0.89; 95% confidence interval, 0.79 to 0.99; p = 0.049). Conclusions The amount of Blood Transfusion is independently associated with infections but not with mortality.
Robert W. Beart – 3rd expert on this subject based on the ideXlab platform
PREDICTING THE USE OF Blood TransfusionWorld Journal of Colorectal surgery, 2020Co-Authors: Robert W. BeartAbstract:
ABSTRACT Background and Purpose Blood Transfusion is associated with post-Transfusion reactions, disease transmission and immunosuppression. Little is known about the incidence of Blood Transfusion in patients undergoing elective colon or rectal resection. The purpose of the present study is to identify the incidence of Blood Transfusion and factors that predict risks of Blood Transfusion in patients undergoing colon and rectal resection. Methods Hospital charts of 206 patients at three hospitals in the Los Angeles area from January 1995 to September 1998 were retrospectively reviewed. Demographic and clinical variables such as age, gender, comorbidities, diagnosis, disease location and operative procedure were recorded. Results The overall Transfusion rate was 48%. The factors that exhibit a positive association with Blood Transfusion include a low pre-operative hemoglobin level (p-value = 0.000002), disease location in the rectum (RR = 1.37 – 2.44), diagnosis of cancer (RR = 1.10 – 2.07), diabetes mellitus (RR = 1.07 – 2.12), history of cerebral vascular accident (RR = 1.86 – 2.51), and documented coronary artery disease (RR – 1.01 – 2.09). Conclusion Factors predicting the need for Blood Transfusion in surgical patients are useful because they may allow implementation of preventative therapy to treat anemia and other conditions. The present study demonstrates a number of pre-operative clinical factors that are predictive of Blood Transfusion.