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Aldo E Calogero - One of the best experts on this subject based on the ideXlab platform.

  • seminal vesicles and diabetic neuropathy ultrasound evaluation after prolonged treatment with a selective phosphodiesterase 5 inhibitor
    Journal of Andrology, 2013
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Francesco Lotti, Vincenzo Favilla, Giuseppe Morgia, Mario Maggi, Aldo E Calogero
    Abstract:

    Summary We have previously reported that infertile patients with diabetes mellitus (DM) have a particular ultrasound features of the seminal vesicles (SV) characterized by higher fundus-to-Body Ratio and lower pre- and post-ejaculatory difference in Body antero-posterior diameter (APD). Based on these premises the aim of the present study was to investigate possible ultrasound SV changes in infertile patients with DM and diabetic neuropathy (DN), after prolonged administRation of tadalafil (TAD) (a specific phosphodiesterase-5 inhibitor). To accomplish this, 20 infertile patients with symptomatic DN and erectile dysfunction were selected and arbitrarily divided into two groups which were assigned to: daily administRation of 5 mg TAD for 3 months (Group A) (n = 10) and administRation of placebo (Group B) (n = 10). All patients underwent to scrotal and prostate-vesicular transrectal ultrasound evaluation and semen analysis (Laboratory Manual for the Examination and Processing of Human Semen, WHO, 2010) before and after treatment. The following SV US parameters were recorded: (i) Body APD; (ii) fundus APD; (iii) parietal thickness of the right and left SVs; and (iv) number of polycyclic areas within both SVs. We then calculated the following parameters: (i) fundus/Body (F/B) Ratio; (ii) difference of the parietal thickness between the right and the left SV and (iii) pre- and post-ejaculatory APD difference. In addition, we also evaluated the SV ejection fraction. Group A patients showed a significant reduction in F/B Ratio and higher pre- and post-ejaculatory Body SV APD difference compared with baseline or Group B after 3 months. These patients showed also a significant increase in SV ejection fraction and a significant improvement of the total sperm count, progressive motility, seminal levels of fructose, leucocytes and ejaculate volume. In conclusion, these results suggest that infertile DM patients with DN and erectile dysfunction had an improvement of ultrasound features suggestive of diabetic neuropathy after daily treatment with low doses of TAD.

  • ultrasound characterization of the seminal vesicles in infertile patients with type 2 diabetes mellitus
    European Journal of Radiology, 2011
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Rosario Dagata, Aldo E Calogero
    Abstract:

    Abstract Male patients with type 2 diabetes mellitus (DM) may experience infertility because the disease affects negatively many aspects of reproduction, including seminal vesicle (SV) function. The aim of this study was to evaluate the ultrasound characteristics of the SVs of infertile patients with DM because no such data are available in these patients. To accomplish this, 25 infertile patients with type 2 DM and no other known causes of sperm parameter abnormalities were selected. Two different control groups were also enrolled: healthy men with idiopathic infertility ( n =25) and infertile patients with male accessory gland infections (MAGI) ( n =25), a well-studied clinical model of SV inflammation. Patients and controls underwent prostate-vesicular transrectal ultrasonography after 1 day of sexual abstinence before and 1h after ejaculation. The following SV ultrasound parameters were recorded: (1) Body antero-posterior diameter (ADP); (2) fundus APD; (3) parietal thickness of the right and left SVs; (4) number of polycyclic areas within both SVs; (5) fundus/Body Ratio; (6) difference of the parietal thickness between the right and the left SV; and (7) pre- and post-ejaculatory APD difference. Patients with DM had a significantly ( p p p

  • seminal vesicles and diabetic neuropathy ultrasound evaluation
    Journal of Andrology, 2011
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Rosario Dagata, Maurizio Di Mauro, Aldo E Calogero
    Abstract:

    The aim of the study was to evaluate the ultrasound characteristics of the seminal vesicles (SV) of infertile patients with diabetes and neuropathy, and possible changes in relation to duRation of diabetes. Sixty infertile patients with type 2 diabetes and symptomatic neuropathy were selected. Patients were divided into 3 groups according to duRation of diabetes (group A ≤ 5 years, group B between 5 and 15 years, and group C ≥ 15 years). A pathological control group of 20 infertile patients without diabetes and a real control group of 20 healthy fertile men were selected and compared. Patients underwent prostate-vesicular transrectal ultrasonography and sperm analysis. The following ultrasound parameters were recorded: 1) Body anteroposterior diameter (APD); 2) fundus APD; 3) parietal thickness of the right and left SVs; 4) number of polycyclic areas within both SVs; 5) fundus-to-Body Ratio; 6) difference of the parietal thickness between the right and the left SVs; and 7) pre-ejaculatory and postejaculatory APD difference. All patients with diabetes had a significantly (P .05) relative to the number of polycyclic areas in patients with diabetes and controls. All patients with diabetes had a significantly lower (P < .05) preejaculatory and postejaculatory difference in Body SV APD compared with controls. Group A and group B had a similar preejaculatory and postejaculatory difference in Body SV APD, whereas this difference was significantly (P < .05) lower in group C. In conclusion, infertile patients with diabetes and neuropathy have peculiar SV ultrasound features suggestive of functional atony, and duRation of disease is associated with worse changes in ultrasound findings.

S La Vignera - One of the best experts on this subject based on the ideXlab platform.

  • seminal vesicles of infertile patients with male accessory gland infection ultrasound evaluation after prolonged treatment with tadalafil a selective phosphodiesterase 5 inhibitor
    Andrologia, 2013
    Co-Authors: S La Vignera
    Abstract:

    Summary The aim of this study was to investigate possible ultrasound seminal vesicle (SV) changes in infertile patients with ‘hypertrophic-congestive’ (HCUF) or ‘fibro-sclerotic’ (FSUF) ultrasound form of male accessory gland infection (MAGI) after prolonged administRation of tadalafil (TAD), a selective phosphodiesterase-5 inhibitor. Forty infertile patients with HCUF and 40 patients with FSUF and erectile dysfunction were selected and arbitrarily divided into two groups, who were prescribed TAD 5 mg daily for 3 months, the first 20 consecutive patients with HCUF (group A1) or FSUF (group A2) or placebo, the second 20 consecutive patients with HCUF (group B1) or FSUF (group B2). All patients underwent scrotal and prostate-vesicular transrectal ultrasound evaluation and semen analysis (WHO, 2010) before and after treatment. Group A1 patients showed a significant reduction in fundus/Body Ratio and higher pre- and post-ejaculatory Body SV antero-posterior diameter difference compared with the other three groups. These patients showed also a significant increase in SV ejection fraction and a significant improvement in the total sperm count, progressive motility, seminal levels of fructose and ejaculate volume. These results suggest that infertile patients with HCUF had an improvement in SV ultrasound features suggestive of chronic inflammation after daily treatment with low doses of TAD.

  • seminal vesicles and diabetic neuropathy ultrasound evaluation after prolonged treatment with a selective phosphodiesterase 5 inhibitor
    Journal of Andrology, 2013
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Francesco Lotti, Vincenzo Favilla, Giuseppe Morgia, Mario Maggi, Aldo E Calogero
    Abstract:

    Summary We have previously reported that infertile patients with diabetes mellitus (DM) have a particular ultrasound features of the seminal vesicles (SV) characterized by higher fundus-to-Body Ratio and lower pre- and post-ejaculatory difference in Body antero-posterior diameter (APD). Based on these premises the aim of the present study was to investigate possible ultrasound SV changes in infertile patients with DM and diabetic neuropathy (DN), after prolonged administRation of tadalafil (TAD) (a specific phosphodiesterase-5 inhibitor). To accomplish this, 20 infertile patients with symptomatic DN and erectile dysfunction were selected and arbitrarily divided into two groups which were assigned to: daily administRation of 5 mg TAD for 3 months (Group A) (n = 10) and administRation of placebo (Group B) (n = 10). All patients underwent to scrotal and prostate-vesicular transrectal ultrasound evaluation and semen analysis (Laboratory Manual for the Examination and Processing of Human Semen, WHO, 2010) before and after treatment. The following SV US parameters were recorded: (i) Body APD; (ii) fundus APD; (iii) parietal thickness of the right and left SVs; and (iv) number of polycyclic areas within both SVs. We then calculated the following parameters: (i) fundus/Body (F/B) Ratio; (ii) difference of the parietal thickness between the right and the left SV and (iii) pre- and post-ejaculatory APD difference. In addition, we also evaluated the SV ejection fraction. Group A patients showed a significant reduction in F/B Ratio and higher pre- and post-ejaculatory Body SV APD difference compared with baseline or Group B after 3 months. These patients showed also a significant increase in SV ejection fraction and a significant improvement of the total sperm count, progressive motility, seminal levels of fructose, leucocytes and ejaculate volume. In conclusion, these results suggest that infertile DM patients with DN and erectile dysfunction had an improvement of ultrasound features suggestive of diabetic neuropathy after daily treatment with low doses of TAD.

  • ultrasound characterization of the seminal vesicles in infertile patients with type 2 diabetes mellitus
    European Journal of Radiology, 2011
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Rosario Dagata, Aldo E Calogero
    Abstract:

    Abstract Male patients with type 2 diabetes mellitus (DM) may experience infertility because the disease affects negatively many aspects of reproduction, including seminal vesicle (SV) function. The aim of this study was to evaluate the ultrasound characteristics of the SVs of infertile patients with DM because no such data are available in these patients. To accomplish this, 25 infertile patients with type 2 DM and no other known causes of sperm parameter abnormalities were selected. Two different control groups were also enrolled: healthy men with idiopathic infertility ( n =25) and infertile patients with male accessory gland infections (MAGI) ( n =25), a well-studied clinical model of SV inflammation. Patients and controls underwent prostate-vesicular transrectal ultrasonography after 1 day of sexual abstinence before and 1h after ejaculation. The following SV ultrasound parameters were recorded: (1) Body antero-posterior diameter (ADP); (2) fundus APD; (3) parietal thickness of the right and left SVs; (4) number of polycyclic areas within both SVs; (5) fundus/Body Ratio; (6) difference of the parietal thickness between the right and the left SV; and (7) pre- and post-ejaculatory APD difference. Patients with DM had a significantly ( p p p

  • seminal vesicles and diabetic neuropathy ultrasound evaluation
    Journal of Andrology, 2011
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Rosario Dagata, Maurizio Di Mauro, Aldo E Calogero
    Abstract:

    The aim of the study was to evaluate the ultrasound characteristics of the seminal vesicles (SV) of infertile patients with diabetes and neuropathy, and possible changes in relation to duRation of diabetes. Sixty infertile patients with type 2 diabetes and symptomatic neuropathy were selected. Patients were divided into 3 groups according to duRation of diabetes (group A ≤ 5 years, group B between 5 and 15 years, and group C ≥ 15 years). A pathological control group of 20 infertile patients without diabetes and a real control group of 20 healthy fertile men were selected and compared. Patients underwent prostate-vesicular transrectal ultrasonography and sperm analysis. The following ultrasound parameters were recorded: 1) Body anteroposterior diameter (APD); 2) fundus APD; 3) parietal thickness of the right and left SVs; 4) number of polycyclic areas within both SVs; 5) fundus-to-Body Ratio; 6) difference of the parietal thickness between the right and the left SVs; and 7) pre-ejaculatory and postejaculatory APD difference. All patients with diabetes had a significantly (P .05) relative to the number of polycyclic areas in patients with diabetes and controls. All patients with diabetes had a significantly lower (P < .05) preejaculatory and postejaculatory difference in Body SV APD compared with controls. Group A and group B had a similar preejaculatory and postejaculatory difference in Body SV APD, whereas this difference was significantly (P < .05) lower in group C. In conclusion, infertile patients with diabetes and neuropathy have peculiar SV ultrasound features suggestive of functional atony, and duRation of disease is associated with worse changes in ultrasound findings.

Enzo Vicari - One of the best experts on this subject based on the ideXlab platform.

  • seminal vesicles and diabetic neuropathy ultrasound evaluation after prolonged treatment with a selective phosphodiesterase 5 inhibitor
    Journal of Andrology, 2013
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Francesco Lotti, Vincenzo Favilla, Giuseppe Morgia, Mario Maggi, Aldo E Calogero
    Abstract:

    Summary We have previously reported that infertile patients with diabetes mellitus (DM) have a particular ultrasound features of the seminal vesicles (SV) characterized by higher fundus-to-Body Ratio and lower pre- and post-ejaculatory difference in Body antero-posterior diameter (APD). Based on these premises the aim of the present study was to investigate possible ultrasound SV changes in infertile patients with DM and diabetic neuropathy (DN), after prolonged administRation of tadalafil (TAD) (a specific phosphodiesterase-5 inhibitor). To accomplish this, 20 infertile patients with symptomatic DN and erectile dysfunction were selected and arbitrarily divided into two groups which were assigned to: daily administRation of 5 mg TAD for 3 months (Group A) (n = 10) and administRation of placebo (Group B) (n = 10). All patients underwent to scrotal and prostate-vesicular transrectal ultrasound evaluation and semen analysis (Laboratory Manual for the Examination and Processing of Human Semen, WHO, 2010) before and after treatment. The following SV US parameters were recorded: (i) Body APD; (ii) fundus APD; (iii) parietal thickness of the right and left SVs; and (iv) number of polycyclic areas within both SVs. We then calculated the following parameters: (i) fundus/Body (F/B) Ratio; (ii) difference of the parietal thickness between the right and the left SV and (iii) pre- and post-ejaculatory APD difference. In addition, we also evaluated the SV ejection fraction. Group A patients showed a significant reduction in F/B Ratio and higher pre- and post-ejaculatory Body SV APD difference compared with baseline or Group B after 3 months. These patients showed also a significant increase in SV ejection fraction and a significant improvement of the total sperm count, progressive motility, seminal levels of fructose, leucocytes and ejaculate volume. In conclusion, these results suggest that infertile DM patients with DN and erectile dysfunction had an improvement of ultrasound features suggestive of diabetic neuropathy after daily treatment with low doses of TAD.

  • ultrasound characterization of the seminal vesicles in infertile patients with type 2 diabetes mellitus
    European Journal of Radiology, 2011
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Rosario Dagata, Aldo E Calogero
    Abstract:

    Abstract Male patients with type 2 diabetes mellitus (DM) may experience infertility because the disease affects negatively many aspects of reproduction, including seminal vesicle (SV) function. The aim of this study was to evaluate the ultrasound characteristics of the SVs of infertile patients with DM because no such data are available in these patients. To accomplish this, 25 infertile patients with type 2 DM and no other known causes of sperm parameter abnormalities were selected. Two different control groups were also enrolled: healthy men with idiopathic infertility ( n =25) and infertile patients with male accessory gland infections (MAGI) ( n =25), a well-studied clinical model of SV inflammation. Patients and controls underwent prostate-vesicular transrectal ultrasonography after 1 day of sexual abstinence before and 1h after ejaculation. The following SV ultrasound parameters were recorded: (1) Body antero-posterior diameter (ADP); (2) fundus APD; (3) parietal thickness of the right and left SVs; (4) number of polycyclic areas within both SVs; (5) fundus/Body Ratio; (6) difference of the parietal thickness between the right and the left SV; and (7) pre- and post-ejaculatory APD difference. Patients with DM had a significantly ( p p p

  • seminal vesicles and diabetic neuropathy ultrasound evaluation
    Journal of Andrology, 2011
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Rosario Dagata, Maurizio Di Mauro, Aldo E Calogero
    Abstract:

    The aim of the study was to evaluate the ultrasound characteristics of the seminal vesicles (SV) of infertile patients with diabetes and neuropathy, and possible changes in relation to duRation of diabetes. Sixty infertile patients with type 2 diabetes and symptomatic neuropathy were selected. Patients were divided into 3 groups according to duRation of diabetes (group A ≤ 5 years, group B between 5 and 15 years, and group C ≥ 15 years). A pathological control group of 20 infertile patients without diabetes and a real control group of 20 healthy fertile men were selected and compared. Patients underwent prostate-vesicular transrectal ultrasonography and sperm analysis. The following ultrasound parameters were recorded: 1) Body anteroposterior diameter (APD); 2) fundus APD; 3) parietal thickness of the right and left SVs; 4) number of polycyclic areas within both SVs; 5) fundus-to-Body Ratio; 6) difference of the parietal thickness between the right and the left SVs; and 7) pre-ejaculatory and postejaculatory APD difference. All patients with diabetes had a significantly (P .05) relative to the number of polycyclic areas in patients with diabetes and controls. All patients with diabetes had a significantly lower (P < .05) preejaculatory and postejaculatory difference in Body SV APD compared with controls. Group A and group B had a similar preejaculatory and postejaculatory difference in Body SV APD, whereas this difference was significantly (P < .05) lower in group C. In conclusion, infertile patients with diabetes and neuropathy have peculiar SV ultrasound features suggestive of functional atony, and duRation of disease is associated with worse changes in ultrasound findings.

Rosita A Condorelli - One of the best experts on this subject based on the ideXlab platform.

  • seminal vesicles and diabetic neuropathy ultrasound evaluation after prolonged treatment with a selective phosphodiesterase 5 inhibitor
    Journal of Andrology, 2013
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Francesco Lotti, Vincenzo Favilla, Giuseppe Morgia, Mario Maggi, Aldo E Calogero
    Abstract:

    Summary We have previously reported that infertile patients with diabetes mellitus (DM) have a particular ultrasound features of the seminal vesicles (SV) characterized by higher fundus-to-Body Ratio and lower pre- and post-ejaculatory difference in Body antero-posterior diameter (APD). Based on these premises the aim of the present study was to investigate possible ultrasound SV changes in infertile patients with DM and diabetic neuropathy (DN), after prolonged administRation of tadalafil (TAD) (a specific phosphodiesterase-5 inhibitor). To accomplish this, 20 infertile patients with symptomatic DN and erectile dysfunction were selected and arbitrarily divided into two groups which were assigned to: daily administRation of 5 mg TAD for 3 months (Group A) (n = 10) and administRation of placebo (Group B) (n = 10). All patients underwent to scrotal and prostate-vesicular transrectal ultrasound evaluation and semen analysis (Laboratory Manual for the Examination and Processing of Human Semen, WHO, 2010) before and after treatment. The following SV US parameters were recorded: (i) Body APD; (ii) fundus APD; (iii) parietal thickness of the right and left SVs; and (iv) number of polycyclic areas within both SVs. We then calculated the following parameters: (i) fundus/Body (F/B) Ratio; (ii) difference of the parietal thickness between the right and the left SV and (iii) pre- and post-ejaculatory APD difference. In addition, we also evaluated the SV ejection fraction. Group A patients showed a significant reduction in F/B Ratio and higher pre- and post-ejaculatory Body SV APD difference compared with baseline or Group B after 3 months. These patients showed also a significant increase in SV ejection fraction and a significant improvement of the total sperm count, progressive motility, seminal levels of fructose, leucocytes and ejaculate volume. In conclusion, these results suggest that infertile DM patients with DN and erectile dysfunction had an improvement of ultrasound features suggestive of diabetic neuropathy after daily treatment with low doses of TAD.

  • ultrasound characterization of the seminal vesicles in infertile patients with type 2 diabetes mellitus
    European Journal of Radiology, 2011
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Rosario Dagata, Aldo E Calogero
    Abstract:

    Abstract Male patients with type 2 diabetes mellitus (DM) may experience infertility because the disease affects negatively many aspects of reproduction, including seminal vesicle (SV) function. The aim of this study was to evaluate the ultrasound characteristics of the SVs of infertile patients with DM because no such data are available in these patients. To accomplish this, 25 infertile patients with type 2 DM and no other known causes of sperm parameter abnormalities were selected. Two different control groups were also enrolled: healthy men with idiopathic infertility ( n =25) and infertile patients with male accessory gland infections (MAGI) ( n =25), a well-studied clinical model of SV inflammation. Patients and controls underwent prostate-vesicular transrectal ultrasonography after 1 day of sexual abstinence before and 1h after ejaculation. The following SV ultrasound parameters were recorded: (1) Body antero-posterior diameter (ADP); (2) fundus APD; (3) parietal thickness of the right and left SVs; (4) number of polycyclic areas within both SVs; (5) fundus/Body Ratio; (6) difference of the parietal thickness between the right and the left SV; and (7) pre- and post-ejaculatory APD difference. Patients with DM had a significantly ( p p p

  • seminal vesicles and diabetic neuropathy ultrasound evaluation
    Journal of Andrology, 2011
    Co-Authors: S La Vignera, Enzo Vicari, Rosita A Condorelli, Rosario Dagata, Maurizio Di Mauro, Aldo E Calogero
    Abstract:

    The aim of the study was to evaluate the ultrasound characteristics of the seminal vesicles (SV) of infertile patients with diabetes and neuropathy, and possible changes in relation to duRation of diabetes. Sixty infertile patients with type 2 diabetes and symptomatic neuropathy were selected. Patients were divided into 3 groups according to duRation of diabetes (group A ≤ 5 years, group B between 5 and 15 years, and group C ≥ 15 years). A pathological control group of 20 infertile patients without diabetes and a real control group of 20 healthy fertile men were selected and compared. Patients underwent prostate-vesicular transrectal ultrasonography and sperm analysis. The following ultrasound parameters were recorded: 1) Body anteroposterior diameter (APD); 2) fundus APD; 3) parietal thickness of the right and left SVs; 4) number of polycyclic areas within both SVs; 5) fundus-to-Body Ratio; 6) difference of the parietal thickness between the right and the left SVs; and 7) pre-ejaculatory and postejaculatory APD difference. All patients with diabetes had a significantly (P .05) relative to the number of polycyclic areas in patients with diabetes and controls. All patients with diabetes had a significantly lower (P < .05) preejaculatory and postejaculatory difference in Body SV APD compared with controls. Group A and group B had a similar preejaculatory and postejaculatory difference in Body SV APD, whereas this difference was significantly (P < .05) lower in group C. In conclusion, infertile patients with diabetes and neuropathy have peculiar SV ultrasound features suggestive of functional atony, and duRation of disease is associated with worse changes in ultrasound findings.

Wenbin Liu - One of the best experts on this subject based on the ideXlab platform.