The Experts below are selected from a list of 4200 Experts worldwide ranked by ideXlab platform
Andrea Z Lacroix - One of the best experts on this subject based on the ideXlab platform.
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The Relationship of Perceived Risk and Biases in Perceived Risk to Fracture Prevention Behavior in Older Women
Annals of Behavioral Medicine, 2015Co-Authors: Salene M. W. Jones, Delia Scholes, Joshua A Roth, Nancy Gell, Andrea Z LacroixAbstract:Background A bias in perceived risk for health outcomes, including fracture, exists. Purpose We compared perceived risk and biases in perceived risk for fracture to fracture preventive behavior. Methods Women over age 55 (n=2874) completed a survey five times over 5 years, and data was pulled from the medical record. Perceived risk was measured by asking women to rate their risk of fracture compared to similar women. Actual risk was measured using FRAX score. Bias was measured using an interaction between perceived and actual risk. Results Higher perceived risk was related to lower quality of life and self-reported health, more medication and calcium use, increased Bone Density Scan use, and less walking. Bias was only associated with less medication use. Neither perceived risk nor bias predicted medication adherence. Conclusions Perceived risk, but not bias, may predict different fracture preventionbehaviors.Cliniciansmay needtobase interventions on risk perceptions.
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The Relationship of Perceived Risk and Biases in Perceived Risk to Fracture Prevention Behavior in Older Women
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2015Co-Authors: Salene M. W. Jones, Delia Scholes, Joshua A Roth, Nancy Gell, Andrea Z LacroixAbstract:Author(s): Jones, Salene MW; Gell, Nancy M; Roth, Joshua A; Scholes, Delia; LaCroix, Andrea Z | Abstract: A bias in perceived risk for health outcomes, including fracture, exists.We compared perceived risk and biases in perceived risk for fracture to fracture preventive behavior.Women over age 55 (n = 2874) completed a survey five times over 5 years, and data was pulled from the medical record. Perceived risk was measured by asking women to rate their risk of fracture compared to similar women. Actual risk was measured using FRAX score. Bias was measured using an interaction between perceived and actual risk.Higher perceived risk was related to lower quality of life and self-reported health, more medication and calcium use, increased Bone Density Scan use, and less walking. Bias was only associated with less medication use. Neither perceived risk nor bias predicted medication adherence.Perceived risk, but not bias, may predict different fracture prevention behaviors. Clinicians may need to base interventions on risk perceptions.
Massimo Tosti Balducci - One of the best experts on this subject based on the ideXlab platform.
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Long-term FEV1 decline and Bone mineral Density in asthma
European Respiratory Journal, 2014Co-Authors: Bruno Sposato, Marco Scalese, Luigi Petruzzelli, Massimo Tosti BalducciAbstract:It is not clear yet whether airway hyperresponsiveness (AHR) and lung function decline can be associated with Bone mineral Density. We therefore retrospectively analyzed 34 asthmatic females (mean age 48.4±9.6;mean baseline FEV1%:99.4±13.1) that had performed a methacholine challenge test (10 hyperreactive subjects; median PD20:358µg, IQR:240-806) and Bone Density Scan (mean femoral-t-score:-0.7±0.9; mean vertebral t-score:-1.3±1.4) at asthma onset. Furthermore, to investigate a link between FEV1 decline and Bone Density changes in time, we considered the 23 asthmatics that had repeated such exam and FEV1 measurements at least 5 years later. No significant relationships were found either between baseline femoral/vertebral-t-scores (r=0.13; r=0.03; p=n.s), and PD20 or FEV1 decline (r=-0.09; r=-0.16; p=n.s). After 7.6±1.7 years, we found a FEV1 decline of 52.9±42.7 ml/year and a mean difference of femoral-t-score 0.09 and vertebral-t-score 0.26 in the 23 asthmatics. When comparing both FEV1 decline and t-score changes in hyperreactive/normoreactive subjects, no differences were found. On the contrary, we detected a significantly positive relationship between changes of femoral-t-scores and FEV1 decline (r=0.43;p=0.04). This suggests an association between Bone Density impoverishment and lung function deterioration, probably due to the inhaled corticosteroids influence on Bone mineral Density. However, since the vitamin D level is associated both with asthma severity and osteopenia/osteoporosis, low levels of this vitamin may negatively influence both Bone Density loss and FEV1 decline. Therefore, when managing asthmatics with an accelerated FEV1 decline, a Bone Density Scan and vitamin D integration should be considered.
Ann Prentice - One of the best experts on this subject based on the ideXlab platform.
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comparison of narrow angle fan beam and pencil beam densitometers in vivo and phantom study of the effect of Bone Density Scan mode and tissue depth on spine measurements
Journal of Clinical Densitometry, 2004Co-Authors: Ann M Laskey, P R Murgatroyd, Ann PrenticeAbstract:Abstract This study compared the in vivo and in vitro performances of the Lunar MD and Prodigy dual-energy X-ray absorptiometers (DXAs). Ten volunteers and three different spine phantoms were studied to determine the effect of Scan mode, tissue depth, and Bone Density on measures of spine Bone area (BA), Bone mineral content (BMC), and areal Bone mineral Density (BMD). These studies demonstrated that the choice of Scan mode was most important for the Prodigy and for subjects who were thin, obese, or had low BMD. Increase in tissue depth caused an increase in measured BMC and BMD for the MD but had a small effect on Prodigy results if the appropriate Scan mode was selected. BA was dependent on the BMD for both DXA systems. Results using a hydroxyapatite phantom demonstrated that after correcting for the calibration of Lunar systems, the BMC measured by the MD and Prodigy was similar to the calculated hydroxyapatite content of the phantom. In vivo studies confirmed the in vitro findings and demonstrated that even when the appropriate Scan mode was selected, the BMC, BMD, and T-scores were significantly higher on the Prodigy than MD.
Pieter Evenepoel - One of the best experts on this subject based on the ideXlab platform.
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Handbook of Parathyroid Diseases: a case-based practical guide - Surgical treatment of persistent hyperparathyroidism after renal transplantation
Annals of surgery, 2008Co-Authors: Frédéric Triponez, Orlo H. Clark, Yves Vanrenthergem, Pieter EvenepoelAbstract:The patient is a 35-year-old man with polycystic kidney disease. He has been on dialysis for 5 years and received a kidney graft 3 months ago. During the course of dialysis, he presented severe secondary hyperparathyroidism (HPT) (parathyroid hormone [PTH]) up to 100 times the upper limit of normal without hypercalcemia and with two parathyroid glands measuring more than 1 cm at ultrasound examination. He did not undergo parathyroidectomy (PTX) because the secondary HPT could be controlled with vitamin D analogues and calcimimetics. Three months after kidney transplantation, he presents with tertiary HPT with hypercalcemia, 10.4 mg/dl (2.6 mmol/l), and high levels of PTH (30 times the upper limit of normal). His Bone Density Scan shows osteopenia.
Bruno Sposato - One of the best experts on this subject based on the ideXlab platform.
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Could a vitamin D deficiency cause a combined long-term FEV1 and Bone mineral Density deterioration in female asthmatics?
La Clinica terapeutica, 2017Co-Authors: Bruno Sposato, Marco Scalese, Luigi Petruzzelli, E. Baldini, N. Nikiforakis, M. Tosti BalducciAbstract:OBJECTIVES We already know that asthma is associated to osteoporosis/osteopenia and characterized by an accelerated lung function decline. Our study aimed at assessing whether lung function decline and Bone mineral Density (BMD) deterioration in time were associated in a group of female long-standing asthmatics. We also tried to understand whether these two aspects were related to ICS treatment and vitamin D levels. METHODS 35 female asthmatics were retrospectively analysed. Results of methacholine challenge test at asthma onset, FEV1%, Bone Density Scan at moment of recruitment and after at least 5years later were considered. RESULTS A significant positive relationship between femoral-t-scores changes and FEV1 decline was found after a median follow-up time of 7 [6-9] years (r=0.43;p=0.04). Femoral-t-score variations and vitamin D values were also significantly related (r=0.669;p=0.024). Furthermore, we found that FEV1 decline was worse in subjects with lower vitamin D levels (-57.5[-80.4-35.9]ml/year), compared to those with normal vitamin D rates (12[-16-23.6]ml/year;p=0.055). Femoral/vertebral t-score changes, as well as FEV1, decline were not associated to the use of medium/high ICS doses when compared to subjects treated with low ICS dosages. CONCLUSIONS FEV ¹ decline and BMD deterioration in time observed in a group of female asthmatics were associated; low vitamin D levels may be the link.
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Long-term FEV1 decline and Bone mineral Density in asthma
European Respiratory Journal, 2014Co-Authors: Bruno Sposato, Marco Scalese, Luigi Petruzzelli, Massimo Tosti BalducciAbstract:It is not clear yet whether airway hyperresponsiveness (AHR) and lung function decline can be associated with Bone mineral Density. We therefore retrospectively analyzed 34 asthmatic females (mean age 48.4±9.6;mean baseline FEV1%:99.4±13.1) that had performed a methacholine challenge test (10 hyperreactive subjects; median PD20:358µg, IQR:240-806) and Bone Density Scan (mean femoral-t-score:-0.7±0.9; mean vertebral t-score:-1.3±1.4) at asthma onset. Furthermore, to investigate a link between FEV1 decline and Bone Density changes in time, we considered the 23 asthmatics that had repeated such exam and FEV1 measurements at least 5 years later. No significant relationships were found either between baseline femoral/vertebral-t-scores (r=0.13; r=0.03; p=n.s), and PD20 or FEV1 decline (r=-0.09; r=-0.16; p=n.s). After 7.6±1.7 years, we found a FEV1 decline of 52.9±42.7 ml/year and a mean difference of femoral-t-score 0.09 and vertebral-t-score 0.26 in the 23 asthmatics. When comparing both FEV1 decline and t-score changes in hyperreactive/normoreactive subjects, no differences were found. On the contrary, we detected a significantly positive relationship between changes of femoral-t-scores and FEV1 decline (r=0.43;p=0.04). This suggests an association between Bone Density impoverishment and lung function deterioration, probably due to the inhaled corticosteroids influence on Bone mineral Density. However, since the vitamin D level is associated both with asthma severity and osteopenia/osteoporosis, low levels of this vitamin may negatively influence both Bone Density loss and FEV1 decline. Therefore, when managing asthmatics with an accelerated FEV1 decline, a Bone Density Scan and vitamin D integration should be considered.