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Yifan Lyu - One of the best experts on this subject based on the ideXlab platform.

  • engineering a 3d dna logic gate nanomachine for bispecific recognition and computing on target cell surfaces
    Journal of the American Chemical Society, 2018
    Co-Authors: Ruizi Peng, Xiaofang Zheng, Yifan Lyu, Xiaobing Zhang, Qiaoling Liu, Changjun You, Shuangyan Huan, Weihong Tan
    Abstract:

    Among the vast number of recognition molecules, DNA aptamers generated from cell-SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular protein receptors on cancer cells. To integrate all recognition and computing modules within a single structure, a three-dimensional (3D) DNA-based logic gate nanomachine was constructed to target overexpressed cancer cell biomarkers with bispecific recognition. Thus, when the Boolean Operator “AND” returns a true value, it is followed by an “ON” signal when the specific cell type is presented. Compared with freely dispersed double-stranded DNA (dsDNA)-based molecular circuits, this 3D DNA nanostructure, termed DNA-logic gate triangular prism (TP), showed better identification performance, enabling, in turn, better molecular targeting and fabrication of recognition nanorobotics.

  • Engineering a 3D DNA-Logic Gate Nanomachine for Bispecific Recognition and Computing on Target Cell Surfaces
    2018
    Co-Authors: Ruizi Peng, Xiaofang Zheng, Yifan Lyu, Xiaobing Zhang, Qiaoling Liu, Changjun You, Shuangyan Huan, Weihong Tan
    Abstract:

    Among the vast number of recognition molecules, DNA aptamers generated from cell-SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular protein receptors on cancer cells. To integrate all recognition and computing modules within a single structure, a three-dimensional (3D) DNA-based logic gate nanomachine was constructed to target overexpressed cancer cell biomarkers with bispecific recognition. Thus, when the Boolean Operator “AND” returns a true value, it is followed by an “ON” signal when the specific cell type is presented. Compared with freely dispersed double-stranded DNA (dsDNA)-based molecular circuits, this 3D DNA nanostructure, termed DNA-logic gate triangular prism (TP), showed better identification performance, enabling, in turn, better molecular targeting and fabrication of recognition nanorobotics

Weihong Tan - One of the best experts on this subject based on the ideXlab platform.

  • engineering a 3d dna logic gate nanomachine for bispecific recognition and computing on target cell surfaces
    Journal of the American Chemical Society, 2018
    Co-Authors: Ruizi Peng, Xiaofang Zheng, Yifan Lyu, Xiaobing Zhang, Qiaoling Liu, Changjun You, Shuangyan Huan, Weihong Tan
    Abstract:

    Among the vast number of recognition molecules, DNA aptamers generated from cell-SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular protein receptors on cancer cells. To integrate all recognition and computing modules within a single structure, a three-dimensional (3D) DNA-based logic gate nanomachine was constructed to target overexpressed cancer cell biomarkers with bispecific recognition. Thus, when the Boolean Operator “AND” returns a true value, it is followed by an “ON” signal when the specific cell type is presented. Compared with freely dispersed double-stranded DNA (dsDNA)-based molecular circuits, this 3D DNA nanostructure, termed DNA-logic gate triangular prism (TP), showed better identification performance, enabling, in turn, better molecular targeting and fabrication of recognition nanorobotics.

  • Engineering a 3D DNA-Logic Gate Nanomachine for Bispecific Recognition and Computing on Target Cell Surfaces
    2018
    Co-Authors: Ruizi Peng, Xiaofang Zheng, Yifan Lyu, Xiaobing Zhang, Qiaoling Liu, Changjun You, Shuangyan Huan, Weihong Tan
    Abstract:

    Among the vast number of recognition molecules, DNA aptamers generated from cell-SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular protein receptors on cancer cells. To integrate all recognition and computing modules within a single structure, a three-dimensional (3D) DNA-based logic gate nanomachine was constructed to target overexpressed cancer cell biomarkers with bispecific recognition. Thus, when the Boolean Operator “AND” returns a true value, it is followed by an “ON” signal when the specific cell type is presented. Compared with freely dispersed double-stranded DNA (dsDNA)-based molecular circuits, this 3D DNA nanostructure, termed DNA-logic gate triangular prism (TP), showed better identification performance, enabling, in turn, better molecular targeting and fabrication of recognition nanorobotics

Oktviani, Ni Putu Wiwik - One of the best experts on this subject based on the ideXlab platform.

  • Risk Factors of Attention Deficit Hyperactivity Disorder (ADHD): Literature Review: Literatur Review: Faktor Risiko Attention Deficit Hyperactivity Disorder (ADHD)
    'STIKes Wira Medika Bali', 2021
    Co-Authors: Adiputra, Made I Sudarma, Pinatih G. N. Indraguna, Trisnadewi, Ni Wayan, Oktviani, Ni Putu Wiwik
    Abstract:

    Pendahuluan: Attention Deficit Hyperactivity Disorder (ADHD) adalah gangguan tumbuh kembang pada anak yang ditandai dengan gangguan aktivitas yang berlebih dan rendahnya perhatian anak usia prasekolah-sekolah. Anak yang menderita ADHD akan sangat sulit diatur dan cenderung mengalami masalah baik dirumah ataupun disekolah. studi literatur ini bertujuan untuk mendapatkan faktor risiko dari kejadian ADHD. Metode dan Hasil : Metode yang digunakan adalah literature review, pencarian  artikel  menggunakan  beberapa sumber  dari  database  : EBSCO HOST, Proquest, PubMed, Scient Direct dan Springer Link publikasi tahun 2010-2020, kata kunci yang digunakan “Risk Faktors”,”adhd or attention deficit hyperactivity disorder, dengan menggunakan “AND” sebagai Boolean Operator. Terdapat sejumlah 309 artikel yang ditemukan sesuai dengan kata kunci tersebut. Setelah artikel tersebut dievaluasi sesuai kriteria yang diinginkan: full text, Bahasa yang digunakan dan kesesuaian rancangan didapatkan sejumlah 18 artikel yang ditelaah untuk di-review. Diskusi: Faktor risiko yang meningkatkan kejadian ADHD: Paparan asap rokok, Ibu merokok dan mengkonsumsi alkohol saat hamil, Ibu hamil yang obesitas, Riwayat kelahiran dengan berat badan lahir rendah (BBLR) dan kelahiran Prematur, APGAR skor rendah saat lahir, genetik dan lingkungan, social ekonomi orang tua, usia orang tua dan Riwayat kelahiran sectio caesaria (SC).Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is a growth and development disorder in children characterized by impaired excessive activity and low attention of preschool-aged children. Children who suffer from ADHD will be very difficult to manage and tend to experience problems both at home or at school. This study literature aimed to obtain risk faktors for the incidence of ADHD. Methods and Results: The method used is literature review, search database using several sources from the database: EBSCO HOST, Proquest, PubMed, Scient Direct and Springer Link 2010-2020 publications, the keywords “Risk Faktors”,”adhd or attention deficit hyperactivity disorder” Boolean Operator “AND”. There are total of 309 articles found in accordance with these keywords. The article was evaluated according to desirable criteria: full text, the language used and the suitability of the design, a total of 18 articles that are used for this review. Discussion: Risk faktors that increase the incidence of ADHD: Exposure to cigarette smoke, smoking and consuming alcohol during pregnancy, obese pregnant women, birth history with low birth weight (LBW) and premature birth, APGAR low score at birth, genetic and environmental conditions, socioeconomic parents, age of parents and birth history of sectio caesaria (SC)

  • Literatur Review: Faktor Risiko Attention Deficit Hyperactivity Disorder (ADHD) : Risk Factors of Attention Deficit Hyperactivity Disorder (ADHD): Literature Review
    'STIKes Wira Medika Bali', 2021
    Co-Authors: Adiputra, Made I Sudarma, Pinatih G. N. Indraguna, Trisnadewi, Ni Wayan, Oktviani, Ni Putu Wiwik
    Abstract:

    Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is a growth and development disorder in children characterized by impaired excessive activity and low attention of preschool-aged children. Children who suffer from ADHD will be very difficult to manage and tend to experience problems both at home or at school. This study literature aimed to obtain risk faktors for the incidence of ADHD. Methods and Results: The method used is literature review, search database using several sources from the database: EBSCO HOST, Proquest, PubMed, Scient Direct and Springer Link 2010-2020 publications, the keywords “Risk Faktors”,”adhd or attention deficit hyperactivity disorder” Boolean Operator “AND”. There are total of 309 articles found in accordance with these keywords. The article was evaluated according to desirable criteria: full text, the language used and the suitability of the design, a total of 18 articles that are used for this review. Discussion: Risk faktors that increase the incidence of ADHD: Exposure to cigarette smoke, smoking and consuming alcohol during pregnancy, obese pregnant women, birth history with low birth weight (LBW) and premature birth, APGAR low score at birth, genetic and environmental conditions, socioeconomic parents, age of parents and birth history of sectio caesaria (SC).Pendahuluan: Attention Deficit Hyperactivity Disorder (ADHD) adalah gangguan tumbuh kembang pada anak yang ditandai dengan gangguan aktivitas yang berlebih dan rendahnya perhatian anak usia prasekolah-sekolah. Anak yang menderita ADHD akan sangat sulit diatur dan cenderung mengalami masalah baik dirumah ataupun disekolah. studi literatur ini bertujuan untuk mendapatkan faktor risiko dari kejadian ADHD. Metode dan Hasil : Metode yang digunakan adalah literature review, pencarian  artikel  menggunakan  beberapa sumber  dari  database  : EBSCO HOST, Proquest, PubMed, Scient Direct dan Springer Link publikasi tahun 2010-2020, kata kunci yang digunakan “Risk Faktors”,”adhd or attention deficit hyperactivity disorder, dengan menggunakan “AND” sebagai Boolean Operator. Terdapat sejumlah 309 artikel yang ditemukan sesuai dengan kata kunci tersebut. Setelah artikel tersebut dievaluasi sesuai kriteria yang diinginkan: full text, Bahasa yang digunakan dan kesesuaian rancangan didapatkan sejumlah 18 artikel yang ditelaah untuk di-review. Diskusi: Faktor risiko yang meningkatkan kejadian ADHD: Paparan asap rokok, Ibu merokok dan mengkonsumsi alkohol saat hamil, Ibu hamil yang obesitas, Riwayat kelahiran dengan berat badan lahir rendah (BBLR) dan kelahiran Prematur, APGAR skor rendah saat lahir, genetik dan lingkungan, social ekonomi orang tua, usia orang tua dan Riwayat kelahiran sectio caesaria (SC)

Ruizi Peng - One of the best experts on this subject based on the ideXlab platform.

  • engineering a 3d dna logic gate nanomachine for bispecific recognition and computing on target cell surfaces
    Journal of the American Chemical Society, 2018
    Co-Authors: Ruizi Peng, Xiaofang Zheng, Yifan Lyu, Xiaobing Zhang, Qiaoling Liu, Changjun You, Shuangyan Huan, Weihong Tan
    Abstract:

    Among the vast number of recognition molecules, DNA aptamers generated from cell-SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular protein receptors on cancer cells. To integrate all recognition and computing modules within a single structure, a three-dimensional (3D) DNA-based logic gate nanomachine was constructed to target overexpressed cancer cell biomarkers with bispecific recognition. Thus, when the Boolean Operator “AND” returns a true value, it is followed by an “ON” signal when the specific cell type is presented. Compared with freely dispersed double-stranded DNA (dsDNA)-based molecular circuits, this 3D DNA nanostructure, termed DNA-logic gate triangular prism (TP), showed better identification performance, enabling, in turn, better molecular targeting and fabrication of recognition nanorobotics.

  • Engineering a 3D DNA-Logic Gate Nanomachine for Bispecific Recognition and Computing on Target Cell Surfaces
    2018
    Co-Authors: Ruizi Peng, Xiaofang Zheng, Yifan Lyu, Xiaobing Zhang, Qiaoling Liu, Changjun You, Shuangyan Huan, Weihong Tan
    Abstract:

    Among the vast number of recognition molecules, DNA aptamers generated from cell-SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular protein receptors on cancer cells. To integrate all recognition and computing modules within a single structure, a three-dimensional (3D) DNA-based logic gate nanomachine was constructed to target overexpressed cancer cell biomarkers with bispecific recognition. Thus, when the Boolean Operator “AND” returns a true value, it is followed by an “ON” signal when the specific cell type is presented. Compared with freely dispersed double-stranded DNA (dsDNA)-based molecular circuits, this 3D DNA nanostructure, termed DNA-logic gate triangular prism (TP), showed better identification performance, enabling, in turn, better molecular targeting and fabrication of recognition nanorobotics

Adiputra, Made I Sudarma - One of the best experts on this subject based on the ideXlab platform.

  • Risk Factors of Attention Deficit Hyperactivity Disorder (ADHD): Literature Review: Literatur Review: Faktor Risiko Attention Deficit Hyperactivity Disorder (ADHD)
    'STIKes Wira Medika Bali', 2021
    Co-Authors: Adiputra, Made I Sudarma, Pinatih G. N. Indraguna, Trisnadewi, Ni Wayan, Oktviani, Ni Putu Wiwik
    Abstract:

    Pendahuluan: Attention Deficit Hyperactivity Disorder (ADHD) adalah gangguan tumbuh kembang pada anak yang ditandai dengan gangguan aktivitas yang berlebih dan rendahnya perhatian anak usia prasekolah-sekolah. Anak yang menderita ADHD akan sangat sulit diatur dan cenderung mengalami masalah baik dirumah ataupun disekolah. studi literatur ini bertujuan untuk mendapatkan faktor risiko dari kejadian ADHD. Metode dan Hasil : Metode yang digunakan adalah literature review, pencarian  artikel  menggunakan  beberapa sumber  dari  database  : EBSCO HOST, Proquest, PubMed, Scient Direct dan Springer Link publikasi tahun 2010-2020, kata kunci yang digunakan “Risk Faktors”,”adhd or attention deficit hyperactivity disorder, dengan menggunakan “AND” sebagai Boolean Operator. Terdapat sejumlah 309 artikel yang ditemukan sesuai dengan kata kunci tersebut. Setelah artikel tersebut dievaluasi sesuai kriteria yang diinginkan: full text, Bahasa yang digunakan dan kesesuaian rancangan didapatkan sejumlah 18 artikel yang ditelaah untuk di-review. Diskusi: Faktor risiko yang meningkatkan kejadian ADHD: Paparan asap rokok, Ibu merokok dan mengkonsumsi alkohol saat hamil, Ibu hamil yang obesitas, Riwayat kelahiran dengan berat badan lahir rendah (BBLR) dan kelahiran Prematur, APGAR skor rendah saat lahir, genetik dan lingkungan, social ekonomi orang tua, usia orang tua dan Riwayat kelahiran sectio caesaria (SC).Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is a growth and development disorder in children characterized by impaired excessive activity and low attention of preschool-aged children. Children who suffer from ADHD will be very difficult to manage and tend to experience problems both at home or at school. This study literature aimed to obtain risk faktors for the incidence of ADHD. Methods and Results: The method used is literature review, search database using several sources from the database: EBSCO HOST, Proquest, PubMed, Scient Direct and Springer Link 2010-2020 publications, the keywords “Risk Faktors”,”adhd or attention deficit hyperactivity disorder” Boolean Operator “AND”. There are total of 309 articles found in accordance with these keywords. The article was evaluated according to desirable criteria: full text, the language used and the suitability of the design, a total of 18 articles that are used for this review. Discussion: Risk faktors that increase the incidence of ADHD: Exposure to cigarette smoke, smoking and consuming alcohol during pregnancy, obese pregnant women, birth history with low birth weight (LBW) and premature birth, APGAR low score at birth, genetic and environmental conditions, socioeconomic parents, age of parents and birth history of sectio caesaria (SC)

  • Literatur Review: Faktor Risiko Attention Deficit Hyperactivity Disorder (ADHD) : Risk Factors of Attention Deficit Hyperactivity Disorder (ADHD): Literature Review
    'STIKes Wira Medika Bali', 2021
    Co-Authors: Adiputra, Made I Sudarma, Pinatih G. N. Indraguna, Trisnadewi, Ni Wayan, Oktviani, Ni Putu Wiwik
    Abstract:

    Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is a growth and development disorder in children characterized by impaired excessive activity and low attention of preschool-aged children. Children who suffer from ADHD will be very difficult to manage and tend to experience problems both at home or at school. This study literature aimed to obtain risk faktors for the incidence of ADHD. Methods and Results: The method used is literature review, search database using several sources from the database: EBSCO HOST, Proquest, PubMed, Scient Direct and Springer Link 2010-2020 publications, the keywords “Risk Faktors”,”adhd or attention deficit hyperactivity disorder” Boolean Operator “AND”. There are total of 309 articles found in accordance with these keywords. The article was evaluated according to desirable criteria: full text, the language used and the suitability of the design, a total of 18 articles that are used for this review. Discussion: Risk faktors that increase the incidence of ADHD: Exposure to cigarette smoke, smoking and consuming alcohol during pregnancy, obese pregnant women, birth history with low birth weight (LBW) and premature birth, APGAR low score at birth, genetic and environmental conditions, socioeconomic parents, age of parents and birth history of sectio caesaria (SC).Pendahuluan: Attention Deficit Hyperactivity Disorder (ADHD) adalah gangguan tumbuh kembang pada anak yang ditandai dengan gangguan aktivitas yang berlebih dan rendahnya perhatian anak usia prasekolah-sekolah. Anak yang menderita ADHD akan sangat sulit diatur dan cenderung mengalami masalah baik dirumah ataupun disekolah. studi literatur ini bertujuan untuk mendapatkan faktor risiko dari kejadian ADHD. Metode dan Hasil : Metode yang digunakan adalah literature review, pencarian  artikel  menggunakan  beberapa sumber  dari  database  : EBSCO HOST, Proquest, PubMed, Scient Direct dan Springer Link publikasi tahun 2010-2020, kata kunci yang digunakan “Risk Faktors”,”adhd or attention deficit hyperactivity disorder, dengan menggunakan “AND” sebagai Boolean Operator. Terdapat sejumlah 309 artikel yang ditemukan sesuai dengan kata kunci tersebut. Setelah artikel tersebut dievaluasi sesuai kriteria yang diinginkan: full text, Bahasa yang digunakan dan kesesuaian rancangan didapatkan sejumlah 18 artikel yang ditelaah untuk di-review. Diskusi: Faktor risiko yang meningkatkan kejadian ADHD: Paparan asap rokok, Ibu merokok dan mengkonsumsi alkohol saat hamil, Ibu hamil yang obesitas, Riwayat kelahiran dengan berat badan lahir rendah (BBLR) dan kelahiran Prematur, APGAR skor rendah saat lahir, genetik dan lingkungan, social ekonomi orang tua, usia orang tua dan Riwayat kelahiran sectio caesaria (SC)