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Timothy Paul Scheett - One of the best experts on this subject based on the ideXlab platform.

  • In a single-blind, matched group design: Branched-Chain Amino Acid supplementation and resistance training maintains lean body mass during a caloric restricted diet
    Journal of the International Society of Sports Nutrition, 2016
    Co-Authors: Wesley David Dudgeon, Elizabeth Page Kelley, Timothy Paul Scheett
    Abstract:

    Background Athletes and active adults many times have the goal of improving/maintaining fitness while losing weight and this is best achieved by caloric restriction in combination with exercise. However, this poses a risk for lean tissue loss, which can limit performance. Thus, the purpose of this study was to determine the effectiveness of a Branched-Chain Amino Acid (BCAA) supplement, in conjunction with heavy resistance training and a carbohydrate caloric-restricted “cut diet” on body composition and muscle fitness. Methods Seventeen resistance-trained males (21–28 years of age) were randomized to a BCAA group ( n  = 9) or a carbohydrate (CHO) group ( n  = 8) who both received their respective supplement during the 8 weeks of a prescribed body building style resistance training protocol. Subjects were prescribed a hypocaloric diet (based upon pre-intervention analysis) that was to be followed during the study. Results The BCAA group lost fat mass (−0.05 ± 0.08 kg; p  

  • in a single blind matched group design branched chain Amino Acid supplementation and resistance training maintains lean body mass during a caloric restricted diet
    Journal of The International Society of Sports Nutrition, 2016
    Co-Authors: Wesley David Dudgeon, Elizabeth Page Kelley, Timothy Paul Scheett
    Abstract:

    Athletes and active adults many times have the goal of improving/maintaining fitness while losing weight and this is best achieved by caloric restriction in combination with exercise. However, this poses a risk for lean tissue loss, which can limit performance. Thus, the purpose of this study was to determine the effectiveness of a Branched-Chain Amino Acid (BCAA) supplement, in conjunction with heavy resistance training and a carbohydrate caloric-restricted “cut diet” on body composition and muscle fitness. Seventeen resistance-trained males (21–28 years of age) were randomized to a BCAA group (n = 9) or a carbohydrate (CHO) group (n = 8) who both received their respective supplement during the 8 weeks of a prescribed body building style resistance training protocol. Subjects were prescribed a hypocaloric diet (based upon pre-intervention analysis) that was to be followed during the study. The BCAA group lost fat mass (−0.05 ± 0.08 kg;p < .05) and maintained lean mass, while the CHO group lost lean mass (−0.90 ± 0.06 kg; p < .05) and body mass (−2.3 ± 0.7 kg; p < .05). Both groups increased 1RM squat, but the increase in the BCAA group (15.1 ± 2.2 kg; p < .05)was greater (P < 0.05) than the CHO group. The BCAA group increased 1RM bench press (7.1 ± 1.6 kg; P < 0.05), while the CHO group decreased strength (−3.7 ± 2.3 kg; P < 0.05). The only change in muscular endurance was an increase in repetitions to fatigue (5.3 ± 0.2; p < .05) in the CHO group. These results show that BCAA supplementation in trained individuals performing resistance training while on a hypocaloric diet can maintain lean mass and preserve skeletal muscle performance while losing fat mass.

Wesley David Dudgeon - One of the best experts on this subject based on the ideXlab platform.

  • In a single-blind, matched group design: Branched-Chain Amino Acid supplementation and resistance training maintains lean body mass during a caloric restricted diet
    Journal of the International Society of Sports Nutrition, 2016
    Co-Authors: Wesley David Dudgeon, Elizabeth Page Kelley, Timothy Paul Scheett
    Abstract:

    Background Athletes and active adults many times have the goal of improving/maintaining fitness while losing weight and this is best achieved by caloric restriction in combination with exercise. However, this poses a risk for lean tissue loss, which can limit performance. Thus, the purpose of this study was to determine the effectiveness of a Branched-Chain Amino Acid (BCAA) supplement, in conjunction with heavy resistance training and a carbohydrate caloric-restricted “cut diet” on body composition and muscle fitness. Methods Seventeen resistance-trained males (21–28 years of age) were randomized to a BCAA group ( n  = 9) or a carbohydrate (CHO) group ( n  = 8) who both received their respective supplement during the 8 weeks of a prescribed body building style resistance training protocol. Subjects were prescribed a hypocaloric diet (based upon pre-intervention analysis) that was to be followed during the study. Results The BCAA group lost fat mass (−0.05 ± 0.08 kg; p  

  • in a single blind matched group design branched chain Amino Acid supplementation and resistance training maintains lean body mass during a caloric restricted diet
    Journal of The International Society of Sports Nutrition, 2016
    Co-Authors: Wesley David Dudgeon, Elizabeth Page Kelley, Timothy Paul Scheett
    Abstract:

    Athletes and active adults many times have the goal of improving/maintaining fitness while losing weight and this is best achieved by caloric restriction in combination with exercise. However, this poses a risk for lean tissue loss, which can limit performance. Thus, the purpose of this study was to determine the effectiveness of a Branched-Chain Amino Acid (BCAA) supplement, in conjunction with heavy resistance training and a carbohydrate caloric-restricted “cut diet” on body composition and muscle fitness. Seventeen resistance-trained males (21–28 years of age) were randomized to a BCAA group (n = 9) or a carbohydrate (CHO) group (n = 8) who both received their respective supplement during the 8 weeks of a prescribed body building style resistance training protocol. Subjects were prescribed a hypocaloric diet (based upon pre-intervention analysis) that was to be followed during the study. The BCAA group lost fat mass (−0.05 ± 0.08 kg;p < .05) and maintained lean mass, while the CHO group lost lean mass (−0.90 ± 0.06 kg; p < .05) and body mass (−2.3 ± 0.7 kg; p < .05). Both groups increased 1RM squat, but the increase in the BCAA group (15.1 ± 2.2 kg; p < .05)was greater (P < 0.05) than the CHO group. The BCAA group increased 1RM bench press (7.1 ± 1.6 kg; P < 0.05), while the CHO group decreased strength (−3.7 ± 2.3 kg; P < 0.05). The only change in muscular endurance was an increase in repetitions to fatigue (5.3 ± 0.2; p < .05) in the CHO group. These results show that BCAA supplementation in trained individuals performing resistance training while on a hypocaloric diet can maintain lean mass and preserve skeletal muscle performance while losing fat mass.

Christian Dubos - One of the best experts on this subject based on the ideXlab platform.

  • Iron–sulfur protein NFU2 is required for Branched-Chain Amino Acid synthesis in Arabidopsis roots
    Journal of Experimental Botany, 2019
    Co-Authors: Brigitte Touraine, Florence Vignols, Jonathan Przybyla-toscano, Till Ischebeck, Tiphaine Dhalleine, Cyril Magno, Nathalie Berger, Jérémy Couturier, Christian Dubos, Ivo Feussner
    Abstract:

    Numerous proteins require a metallic co-factor for their function. In plastids, the maturation of iron-sulfur (Fe-S) proteins necessitates a complex assembly machinery. In this study, we focused on Arabidopsis thaliana NFU1, NFU2, and NFU3, which participate in the final steps of the maturation process. According to the strong photosynthetic defects observed in high chlorophyll fluorescence 101 (hcf101), nfu2, and nfu3 plants, we determined that NFU2 and NFU3, but not NFU1, act immediately upstream of HCF101 for the maturation of [Fe4S4]-containing photosystem I subunits. An additional function of NFU2 in the maturation of the [Fe2S2] cluster of a dihydroxyAcid dehydratase was obvious from the accumulation of precursors of the Branched-Chain Amino Acid synthesis pathway in roots of nfu2 plants and from the rescue of the primary root growth defect by supplying Branched-Chain Amino Acids. The absence of NFU3 in roots precluded any compensation. Overall, unlike their eukaryotic and prokaryotic counterparts, which are specific to [Fe4S4] proteins, NFU2 and NFU3 contribute to the maturation of both [Fe2S2] and [Fe4S4] proteins, either as a relay in conjunction with other proteins such as HCF101 or by directly delivering Fe-S clusters to client proteins. Considering the low number of Fe-S cluster transfer proteins relative to final acceptors, additional targets probably await identification.

  • Iron-sulfur protein NFU2 is required for Branched-Chain Amino Acid synthesis in Arabidopsis roots.
    Journal of experimental botany, 2019
    Co-Authors: Brigitte Touraine, Florence Vignols, Jonathan Przybyla-toscano, Till Ischebeck, Tiphaine Dhalleine, Cyril Magno, Nathalie Berger, Jérémy Couturier, Christian Dubos
    Abstract:

    Numerous proteins require a metallic co-factor for their function. In plastids, the maturation of iron-sulfur (Fe-S) proteins necessitates a complex assembly machinery. In this study, we focused on Arabidopsis thaliana NFU1, NFU2, and NFU3, which participate in the final steps of the maturation process. According to the strong photosynthetic defects observed in high chlorophyll fluorescence 101 (hcf101), nfu2, and nfu3 plants, we determined that NFU2 and NFU3, but not NFU1, act immediately upstream of HCF101 for the maturation of [Fe4S4]-containing photosystem I subunits. An additional function of NFU2 in the maturation of the [Fe2S2] cluster of a dihydroxyAcid dehydratase was obvious from the accumulation of precursors of the Branched-Chain Amino Acid synthesis pathway in roots of nfu2 plants and from the rescue of the primary root growth defect by supplying Branched-Chain Amino Acids. The absence of NFU3 in roots precluded any compensation. Overall, unlike their eukaryotic and prokaryotic counterparts, which are specific to [Fe4S4] proteins, NFU2 and NFU3 contribute to the maturation of both [Fe2S2] and [Fe4S4] proteins, either as a relay in conjunction with other proteins such as HCF101 or by directly delivering Fe-S clusters to client proteins. Considering the low number of Fe-S cluster transfer proteins relative to final acceptors, additional targets probably await identification.

Brigitte Touraine - One of the best experts on this subject based on the ideXlab platform.

  • Iron–sulfur protein NFU2 is required for Branched-Chain Amino Acid synthesis in Arabidopsis roots
    Journal of Experimental Botany, 2019
    Co-Authors: Brigitte Touraine, Florence Vignols, Jonathan Przybyla-toscano, Till Ischebeck, Tiphaine Dhalleine, Cyril Magno, Nathalie Berger, Jérémy Couturier, Christian Dubos, Ivo Feussner
    Abstract:

    Numerous proteins require a metallic co-factor for their function. In plastids, the maturation of iron-sulfur (Fe-S) proteins necessitates a complex assembly machinery. In this study, we focused on Arabidopsis thaliana NFU1, NFU2, and NFU3, which participate in the final steps of the maturation process. According to the strong photosynthetic defects observed in high chlorophyll fluorescence 101 (hcf101), nfu2, and nfu3 plants, we determined that NFU2 and NFU3, but not NFU1, act immediately upstream of HCF101 for the maturation of [Fe4S4]-containing photosystem I subunits. An additional function of NFU2 in the maturation of the [Fe2S2] cluster of a dihydroxyAcid dehydratase was obvious from the accumulation of precursors of the Branched-Chain Amino Acid synthesis pathway in roots of nfu2 plants and from the rescue of the primary root growth defect by supplying Branched-Chain Amino Acids. The absence of NFU3 in roots precluded any compensation. Overall, unlike their eukaryotic and prokaryotic counterparts, which are specific to [Fe4S4] proteins, NFU2 and NFU3 contribute to the maturation of both [Fe2S2] and [Fe4S4] proteins, either as a relay in conjunction with other proteins such as HCF101 or by directly delivering Fe-S clusters to client proteins. Considering the low number of Fe-S cluster transfer proteins relative to final acceptors, additional targets probably await identification.

  • Iron-sulfur protein NFU2 is required for Branched-Chain Amino Acid synthesis in Arabidopsis roots.
    Journal of experimental botany, 2019
    Co-Authors: Brigitte Touraine, Florence Vignols, Jonathan Przybyla-toscano, Till Ischebeck, Tiphaine Dhalleine, Cyril Magno, Nathalie Berger, Jérémy Couturier, Christian Dubos
    Abstract:

    Numerous proteins require a metallic co-factor for their function. In plastids, the maturation of iron-sulfur (Fe-S) proteins necessitates a complex assembly machinery. In this study, we focused on Arabidopsis thaliana NFU1, NFU2, and NFU3, which participate in the final steps of the maturation process. According to the strong photosynthetic defects observed in high chlorophyll fluorescence 101 (hcf101), nfu2, and nfu3 plants, we determined that NFU2 and NFU3, but not NFU1, act immediately upstream of HCF101 for the maturation of [Fe4S4]-containing photosystem I subunits. An additional function of NFU2 in the maturation of the [Fe2S2] cluster of a dihydroxyAcid dehydratase was obvious from the accumulation of precursors of the Branched-Chain Amino Acid synthesis pathway in roots of nfu2 plants and from the rescue of the primary root growth defect by supplying Branched-Chain Amino Acids. The absence of NFU3 in roots precluded any compensation. Overall, unlike their eukaryotic and prokaryotic counterparts, which are specific to [Fe4S4] proteins, NFU2 and NFU3 contribute to the maturation of both [Fe2S2] and [Fe4S4] proteins, either as a relay in conjunction with other proteins such as HCF101 or by directly delivering Fe-S clusters to client proteins. Considering the low number of Fe-S cluster transfer proteins relative to final acceptors, additional targets probably await identification.

Elizabeth Page Kelley - One of the best experts on this subject based on the ideXlab platform.

  • In a single-blind, matched group design: Branched-Chain Amino Acid supplementation and resistance training maintains lean body mass during a caloric restricted diet
    Journal of the International Society of Sports Nutrition, 2016
    Co-Authors: Wesley David Dudgeon, Elizabeth Page Kelley, Timothy Paul Scheett
    Abstract:

    Background Athletes and active adults many times have the goal of improving/maintaining fitness while losing weight and this is best achieved by caloric restriction in combination with exercise. However, this poses a risk for lean tissue loss, which can limit performance. Thus, the purpose of this study was to determine the effectiveness of a Branched-Chain Amino Acid (BCAA) supplement, in conjunction with heavy resistance training and a carbohydrate caloric-restricted “cut diet” on body composition and muscle fitness. Methods Seventeen resistance-trained males (21–28 years of age) were randomized to a BCAA group ( n  = 9) or a carbohydrate (CHO) group ( n  = 8) who both received their respective supplement during the 8 weeks of a prescribed body building style resistance training protocol. Subjects were prescribed a hypocaloric diet (based upon pre-intervention analysis) that was to be followed during the study. Results The BCAA group lost fat mass (−0.05 ± 0.08 kg; p  

  • in a single blind matched group design branched chain Amino Acid supplementation and resistance training maintains lean body mass during a caloric restricted diet
    Journal of The International Society of Sports Nutrition, 2016
    Co-Authors: Wesley David Dudgeon, Elizabeth Page Kelley, Timothy Paul Scheett
    Abstract:

    Athletes and active adults many times have the goal of improving/maintaining fitness while losing weight and this is best achieved by caloric restriction in combination with exercise. However, this poses a risk for lean tissue loss, which can limit performance. Thus, the purpose of this study was to determine the effectiveness of a Branched-Chain Amino Acid (BCAA) supplement, in conjunction with heavy resistance training and a carbohydrate caloric-restricted “cut diet” on body composition and muscle fitness. Seventeen resistance-trained males (21–28 years of age) were randomized to a BCAA group (n = 9) or a carbohydrate (CHO) group (n = 8) who both received their respective supplement during the 8 weeks of a prescribed body building style resistance training protocol. Subjects were prescribed a hypocaloric diet (based upon pre-intervention analysis) that was to be followed during the study. The BCAA group lost fat mass (−0.05 ± 0.08 kg;p < .05) and maintained lean mass, while the CHO group lost lean mass (−0.90 ± 0.06 kg; p < .05) and body mass (−2.3 ± 0.7 kg; p < .05). Both groups increased 1RM squat, but the increase in the BCAA group (15.1 ± 2.2 kg; p < .05)was greater (P < 0.05) than the CHO group. The BCAA group increased 1RM bench press (7.1 ± 1.6 kg; P < 0.05), while the CHO group decreased strength (−3.7 ± 2.3 kg; P < 0.05). The only change in muscular endurance was an increase in repetitions to fatigue (5.3 ± 0.2; p < .05) in the CHO group. These results show that BCAA supplementation in trained individuals performing resistance training while on a hypocaloric diet can maintain lean mass and preserve skeletal muscle performance while losing fat mass.