The Experts below are selected from a list of 738 Experts worldwide ranked by ideXlab platform
Maurice Y Nahabedian - One of the best experts on this subject based on the ideXlab platform.
-
acellular dermal matrix for the treatment and prevention of implant associated Breast deformities
Plastic and Reconstructive Surgery, 2011Co-Authors: Scott L Spear, Mitchel Seruya, Mark W Clemens, Steven Teitelbaum, Maurice Y NahabedianAbstract:Background Acellular dermal matrix has been increasingly accepted in prosthetic Breast reconstruction. Observed benefits include improved control and support of implant position, better implant coverage, and the suggestion of a decreased capsular contracture rate. Based on this positive experience, it is not surprising that acellular dermal matrix would be applied to other challenging implant-related problems. This study investigates the use of acellular dermal matrix for correction or prevention of implant-associated Breast deformities. Methods Patients who underwent primary aesthetic Breast surgery or secondary aesthetic or reconstructive Breast surgery using acellular dermal matrix and implants between November of 2003 and October of 2009 were reviewed retrospectively. Patient demographics, indications for acellular dermal matrix, and acellular dermal matrix type and inset pattern were identified. Preoperative and postoperative photographs, success or failure of the procedure, complications, and need for related or unrelated revision surgery were recorded. Results Fifty-two patients had acellular dermal matrix placed alongside 77 Breast Prostheses, with a mean follow-up of 8.6 months (range, 0.4 to 30.4 months). Indications included prevention of implant bottoming-out (n = 6), treatment of malposition (n = 32), rippling (n = 20), capsular contracture (n = 16), and skin flap deficiency (n = 16). Seventy-four Breasts (96.1 percent) were managed successfully with acellular dermal matrix. Three failures consisted of one Breast with bottoming-out following treatment of capsular contracture, one Breast with major infection requiring device explantation, and one Breast with recurrent rippling. There was a 9.1 percent total complication rate, consisting of three mild infections, one major infection necessitating explantation, one hematoma, and one seroma. Conclusion Based on this experience in 77 Breasts, acellular dermal matrix has shown promise in treating and preventing capsular contracture, rippling, implant malposition, and soft-tissue thinning.
Scott L Spear - One of the best experts on this subject based on the ideXlab platform.
-
acellular dermal matrix for the treatment and prevention of implant associated Breast deformities
Plastic and Reconstructive Surgery, 2011Co-Authors: Scott L Spear, Mitchel Seruya, Mark W Clemens, Steven Teitelbaum, Maurice Y NahabedianAbstract:Background Acellular dermal matrix has been increasingly accepted in prosthetic Breast reconstruction. Observed benefits include improved control and support of implant position, better implant coverage, and the suggestion of a decreased capsular contracture rate. Based on this positive experience, it is not surprising that acellular dermal matrix would be applied to other challenging implant-related problems. This study investigates the use of acellular dermal matrix for correction or prevention of implant-associated Breast deformities. Methods Patients who underwent primary aesthetic Breast surgery or secondary aesthetic or reconstructive Breast surgery using acellular dermal matrix and implants between November of 2003 and October of 2009 were reviewed retrospectively. Patient demographics, indications for acellular dermal matrix, and acellular dermal matrix type and inset pattern were identified. Preoperative and postoperative photographs, success or failure of the procedure, complications, and need for related or unrelated revision surgery were recorded. Results Fifty-two patients had acellular dermal matrix placed alongside 77 Breast Prostheses, with a mean follow-up of 8.6 months (range, 0.4 to 30.4 months). Indications included prevention of implant bottoming-out (n = 6), treatment of malposition (n = 32), rippling (n = 20), capsular contracture (n = 16), and skin flap deficiency (n = 16). Seventy-four Breasts (96.1 percent) were managed successfully with acellular dermal matrix. Three failures consisted of one Breast with bottoming-out following treatment of capsular contracture, one Breast with major infection requiring device explantation, and one Breast with recurrent rippling. There was a 9.1 percent total complication rate, consisting of three mild infections, one major infection necessitating explantation, one hematoma, and one seroma. Conclusion Based on this experience in 77 Breasts, acellular dermal matrix has shown promise in treating and preventing capsular contracture, rippling, implant malposition, and soft-tissue thinning.
Matteo Malacco - One of the best experts on this subject based on the ideXlab platform.
-
chemical and physicochemical properties of the high cohesive silicone gel from poly implant prothese pip Breast Prostheses after explantation a preliminary comparative analytical investigation
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Giangiacomo Beretta, Matteo MalaccoAbstract:Aim of this work was to gain a deeper insight into the analytical profile of the macromolecular and LMW fractions of polymeric silicones present in Breast implants. The study was conducted on silicone gel samples from (i) Breast Prostheses (Poly Implant Prothese, PIP) explanted from a patient that needed their therapeutical removal, (ii) from a virgin Mc Ghan 410 MX prosthesis and (iii) from a sample of technical-grade non-cohesive silicone. The gels were analysed using rheological techniques, attenuated total reflectance infrared spectroscopy (ATR-FT-IR), nuclear magnetic resonance ((1)H NMR), gas chromatography coupled to mass spectrometry (GC-MS) and flow injection electrospray mass spectrometry (FI-ESI-MS). Our results demonstrate that, compared to the virgin McGhan gel, the silicone present the PIP Prostheses lacks a significant part of the cross-linking sites necessary for the high-cohesive properties of the gel, significant amounts of cholesterol have been absorbed from the Breast tissue by the silicone material, demonstrating the lack of impermeability of its elastomer shell. The potential implications and consequences of these analytical results are discussed.
-
Chemical and physicochemical properties of the high cohesive silicone gel from Poly Implant Prothèse (PIP) Breast Prostheses after explantation : a preliminary, comparative analytical investigation
'Elsevier BV', 2013Co-Authors: Giangiacomo Beretta, Matteo MalaccoAbstract:Aim of this work was to gain a deeper insight into the analytical profile of the macromolecular and LMW fractions of polymeric silicones present in Breast implants. The study was conducted on silicone gel samples from (i) Breast Prostheses (Poly Implant Proth\ue8se, PIP) explanted from a patient that needed their therapeutical removal, (ii) from a virgin Mc Ghan 410 MX prosthesis and (iii) from a sample of technical-grade non-cohesive silicone. The gels were analysed using rheological techniques, attenuated total reflectance infrared spectroscopy (ATR-FT-IR), nuclear magnetic resonance ((1)H NMR), gas chromatography coupled to mass spectrometry (GC-MS) and flow injection electrospray mass spectrometry (FI-ESI-MS). Our results demonstrate that, compared to the virgin McGhan gel, the silicone present the PIP Prostheses lacks a significant part of the cross-linking sites necessary for the high-cohesive properties of the gel, significant amounts of cholesterol have been absorbed from the Breast tissue by the silicone material, demonstrating the lack of impermeability of its elastomer shell. The potential implications and consequences of these analytical results are discussed
Steven Teitelbaum - One of the best experts on this subject based on the ideXlab platform.
-
acellular dermal matrix for the treatment and prevention of implant associated Breast deformities
Plastic and Reconstructive Surgery, 2011Co-Authors: Scott L Spear, Mitchel Seruya, Mark W Clemens, Steven Teitelbaum, Maurice Y NahabedianAbstract:Background Acellular dermal matrix has been increasingly accepted in prosthetic Breast reconstruction. Observed benefits include improved control and support of implant position, better implant coverage, and the suggestion of a decreased capsular contracture rate. Based on this positive experience, it is not surprising that acellular dermal matrix would be applied to other challenging implant-related problems. This study investigates the use of acellular dermal matrix for correction or prevention of implant-associated Breast deformities. Methods Patients who underwent primary aesthetic Breast surgery or secondary aesthetic or reconstructive Breast surgery using acellular dermal matrix and implants between November of 2003 and October of 2009 were reviewed retrospectively. Patient demographics, indications for acellular dermal matrix, and acellular dermal matrix type and inset pattern were identified. Preoperative and postoperative photographs, success or failure of the procedure, complications, and need for related or unrelated revision surgery were recorded. Results Fifty-two patients had acellular dermal matrix placed alongside 77 Breast Prostheses, with a mean follow-up of 8.6 months (range, 0.4 to 30.4 months). Indications included prevention of implant bottoming-out (n = 6), treatment of malposition (n = 32), rippling (n = 20), capsular contracture (n = 16), and skin flap deficiency (n = 16). Seventy-four Breasts (96.1 percent) were managed successfully with acellular dermal matrix. Three failures consisted of one Breast with bottoming-out following treatment of capsular contracture, one Breast with major infection requiring device explantation, and one Breast with recurrent rippling. There was a 9.1 percent total complication rate, consisting of three mild infections, one major infection necessitating explantation, one hematoma, and one seroma. Conclusion Based on this experience in 77 Breasts, acellular dermal matrix has shown promise in treating and preventing capsular contracture, rippling, implant malposition, and soft-tissue thinning.
Mitchel Seruya - One of the best experts on this subject based on the ideXlab platform.
-
acellular dermal matrix for the treatment and prevention of implant associated Breast deformities
Plastic and Reconstructive Surgery, 2011Co-Authors: Scott L Spear, Mitchel Seruya, Mark W Clemens, Steven Teitelbaum, Maurice Y NahabedianAbstract:Background Acellular dermal matrix has been increasingly accepted in prosthetic Breast reconstruction. Observed benefits include improved control and support of implant position, better implant coverage, and the suggestion of a decreased capsular contracture rate. Based on this positive experience, it is not surprising that acellular dermal matrix would be applied to other challenging implant-related problems. This study investigates the use of acellular dermal matrix for correction or prevention of implant-associated Breast deformities. Methods Patients who underwent primary aesthetic Breast surgery or secondary aesthetic or reconstructive Breast surgery using acellular dermal matrix and implants between November of 2003 and October of 2009 were reviewed retrospectively. Patient demographics, indications for acellular dermal matrix, and acellular dermal matrix type and inset pattern were identified. Preoperative and postoperative photographs, success or failure of the procedure, complications, and need for related or unrelated revision surgery were recorded. Results Fifty-two patients had acellular dermal matrix placed alongside 77 Breast Prostheses, with a mean follow-up of 8.6 months (range, 0.4 to 30.4 months). Indications included prevention of implant bottoming-out (n = 6), treatment of malposition (n = 32), rippling (n = 20), capsular contracture (n = 16), and skin flap deficiency (n = 16). Seventy-four Breasts (96.1 percent) were managed successfully with acellular dermal matrix. Three failures consisted of one Breast with bottoming-out following treatment of capsular contracture, one Breast with major infection requiring device explantation, and one Breast with recurrent rippling. There was a 9.1 percent total complication rate, consisting of three mild infections, one major infection necessitating explantation, one hematoma, and one seroma. Conclusion Based on this experience in 77 Breasts, acellular dermal matrix has shown promise in treating and preventing capsular contracture, rippling, implant malposition, and soft-tissue thinning.