The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Hideo Ishikawa - One of the best experts on this subject based on the ideXlab platform.
-
spinal cord infarction after Bronchial Artery embolization for hemoptysis a nationwide observational study in japan
Radiology, 2021Co-Authors: Hideo Ishikawa, Hiroyuki Ohbe, Naoki Omachi, Kojiro Morita, Hideo YasunagaAbstract:In a nationwide administrative database evaluated over a 9-year period, the rate of spinal cord infarction after Bronchial Artery embolization for hemoptysis was 0.19%.
-
mechanisms of recurrent haemoptysis after super selective Bronchial Artery coil embolisation a single centre retrospective observational study
European Radiology, 2019Co-Authors: Misaki Ryuge, Naoki Omachi, Masahiko Hara, Takanori Hiroe, Shojiro Minomo, Kazushi Kitaguchi, Mihoko Youmoto, Norihiro Asakura, Yasushi Sakata, Hideo IshikawaAbstract:In recognition of the significant impairment caused by haemoptysis on a patient’s quality of life, Bronchial Artery embolisation has been introduced worldwide as one of the first-line treatment options. Since little evidence is available on the mechanisms of recurrent haemoptysis after super-selective Bronchial Artery coil embolisation (ssBACE), the purpose of the present study is to evaluate these. We retrospectively evaluated the mechanisms of recurrent haemoptysis using both enhanced computed tomography and cineangiography following ssBACE by reviewing 299 haemoptysis-related arteries (HRAs) in 57 consecutive patients who underwent 2nd series ssBACE for the management of recurrent haemoptysis between April 2010 and December 2015. Median age of patients was 69 (interquartile range 64–74) years, and 43.9% were men. This study revealed that (1) recanalisation was the most common mechanism (45.2%) followed by development of new HRA (38.5%), bridging collaterals (14.7%) and conventional collaterals (1.7%); (2) these trends could be modified in several situations such as with antiplatelet or anticoagulant medications; (3) relatively large-diameter HRAs were more likely to recanalise compared with small-diameter HRAs and (4) recurrent haemoptysis could be managed by 2nd series ssBACE with a procedural success rate of 97.7% without any major complications. Recanalisation was the most common mechanism of recurrent haemoptysis after ssBACE. Our results provide interventionists with indispensable insights. • Recanalisation was the most common mechanism of recurrent haemoptysis after super-selective Bronchial Artery coil embolisation, followed by development of new haemoptysis-related arteries • These trends could be modified in several situations such as with antiplatelet or anticoagulant medications • Recurrent haemoptysis could be managed by 2nd series super-selective Bronchial Artery coil embolisation with a procedural success rate of 97.7% without any major complications.
Hideo Yasunaga - One of the best experts on this subject based on the ideXlab platform.
-
spinal cord infarction after Bronchial Artery embolization for hemoptysis a nationwide observational study in japan
Radiology, 2021Co-Authors: Hideo Ishikawa, Hiroyuki Ohbe, Naoki Omachi, Kojiro Morita, Hideo YasunagaAbstract:In a nationwide administrative database evaluated over a 9-year period, the rate of spinal cord infarction after Bronchial Artery embolization for hemoptysis was 0.19%.
Naoki Omachi - One of the best experts on this subject based on the ideXlab platform.
-
spinal cord infarction after Bronchial Artery embolization for hemoptysis a nationwide observational study in japan
Radiology, 2021Co-Authors: Hideo Ishikawa, Hiroyuki Ohbe, Naoki Omachi, Kojiro Morita, Hideo YasunagaAbstract:In a nationwide administrative database evaluated over a 9-year period, the rate of spinal cord infarction after Bronchial Artery embolization for hemoptysis was 0.19%.
-
mechanisms of recurrent haemoptysis after super selective Bronchial Artery coil embolisation a single centre retrospective observational study
European Radiology, 2019Co-Authors: Misaki Ryuge, Naoki Omachi, Masahiko Hara, Takanori Hiroe, Shojiro Minomo, Kazushi Kitaguchi, Mihoko Youmoto, Norihiro Asakura, Yasushi Sakata, Hideo IshikawaAbstract:In recognition of the significant impairment caused by haemoptysis on a patient’s quality of life, Bronchial Artery embolisation has been introduced worldwide as one of the first-line treatment options. Since little evidence is available on the mechanisms of recurrent haemoptysis after super-selective Bronchial Artery coil embolisation (ssBACE), the purpose of the present study is to evaluate these. We retrospectively evaluated the mechanisms of recurrent haemoptysis using both enhanced computed tomography and cineangiography following ssBACE by reviewing 299 haemoptysis-related arteries (HRAs) in 57 consecutive patients who underwent 2nd series ssBACE for the management of recurrent haemoptysis between April 2010 and December 2015. Median age of patients was 69 (interquartile range 64–74) years, and 43.9% were men. This study revealed that (1) recanalisation was the most common mechanism (45.2%) followed by development of new HRA (38.5%), bridging collaterals (14.7%) and conventional collaterals (1.7%); (2) these trends could be modified in several situations such as with antiplatelet or anticoagulant medications; (3) relatively large-diameter HRAs were more likely to recanalise compared with small-diameter HRAs and (4) recurrent haemoptysis could be managed by 2nd series ssBACE with a procedural success rate of 97.7% without any major complications. Recanalisation was the most common mechanism of recurrent haemoptysis after ssBACE. Our results provide interventionists with indispensable insights. • Recanalisation was the most common mechanism of recurrent haemoptysis after super-selective Bronchial Artery coil embolisation, followed by development of new haemoptysis-related arteries • These trends could be modified in several situations such as with antiplatelet or anticoagulant medications • Recurrent haemoptysis could be managed by 2nd series super-selective Bronchial Artery coil embolisation with a procedural success rate of 97.7% without any major complications.
Anthony C Brown - One of the best experts on this subject based on the ideXlab platform.
-
anterior spinal cord infarction following Bronchial Artery embolization
Seminars in Interventional Radiology, 2012Co-Authors: Anthony C BrownAbstract:Embolization of an anterior spinal Artery is a rare complication that can occur during Bronchial Artery embolization, typically performed for massive hemoptysis. Embolization of this important blood supply to the anterior spinal cord can result in infarction and paralysis. Every interventional radiologist should have an intimate knowledge of Bronchial Artery anatomy and must make every effort to delineate spinal Artery feeders during the procedure.
Daniel L. Traber - One of the best experts on this subject based on the ideXlab platform.
-
direct delivery of low dose 7 nitroindazole into the Bronchial Artery attenuates pulmonary pathophysiology after smoke inhalation and burn injury in an ovine model
Shock, 2011Co-Authors: Atsumori Hamahata, Perenlei Enkhbaatar, Hal K Hawkins, Matthias Lange, Hiroyuki Sakurai, Lillian D. Traber, Daniel L. TraberAbstract:: Bronchial circulation plays a critical role in the pathophysiology of burn and smoke inhalation-induced acute lung injury. A 10-fold increase in Bronchial blood flow is associated with excessive production of nitric oxide (NO) following smoke inhalation and cutaneous burn. Because an increased release of neuropeptides from the airway has been implicated in smoke inhalation injury, we hypothesized that direct delivery into the Bronchial Artery of low-dose 7-nitroindazole (7-NI), a specific neuronal NO synthase inhibitor, would attenuate smoke/burn-induced acute lung injury. Eighteen adult female sheep were instrumented for chronic hemodynamic monitoring 5 to 7 days before the injury. The Bronchial Artery was cannulated via intercostal thoracotomy, while blood flow was preserved. Acute lung injury was induced by 40% total body surface area third-degree cutaneous burn and smoke inhalation (48 breaths of cotton smoke, <40°C) under deep anesthesia. Following injury, animals (35.4 ± 1.1 kg) were divided into three groups: (a) 7-NI group: 1 h after injury, 7-NI (0.01 mg · kg · h, 2 mL · h) was continuously infused into the Bronchial Artery, n = 6; (b) control group: 1 h after injury, same amount of saline was injected into the Bronchial Artery, n = 6; (c) sham group: no injury, no treatment, same operation and anesthesia, n = 6. After injury, all animals were ventilated and fluid resuscitated according to an established protocol. The experiment was conducted for 24 h. Injury induced severe pulmonary dysfunction, which was associated with increases in lung edema formation, airway obstruction, malondialdehyde, and nitrate/nitrite. 7-Nitroindazole injection into the Bronchial Artery reduced the degree of lung edema formation and improved pulmonary gas exchange. The increase in malondialdehyde and nitrate/nitrite in lung tissue was attenuated by treatment. Our data strongly suggest that local airway production of NO contributes to pulmonary dysfunction following smoke inhalation and burn injury. Most mechanisms that drive this pathophysiology reside in the airway.
-
Sclerosis therapy of Bronchial Artery attenuates acute lung injury induced by burn and smoke inhalation injury in ovine model
Burns : journal of the International Society for Burn Injuries, 2010Co-Authors: Atsumori Hamahata, Perenlei Enkhbaatar, Hiroyuki Sakurai, Motohiro Nozaki, Daniel L. TraberAbstract:Abstract Introduction In burned sheep, we showed more than a 10-fold increase in Bronchial blood flow following smoke inhalation. It was previously reported that sclerosis of the Bronchial Artery prior to smoke exposure reduces the pathophysiology of the inhalation insult. We hypothesized that sclerosis of the Bronchial Artery after insult attenuates smoke/burn-induced acute lung injury. Methods Through an incision at the 4th intercostal space, a catheter was placed via the esophageal Artery into the Bronchial Artery such that the Bronchial blood flow remained intact. Acute lung injury was induced by a 40% total body surface area, 3rd degree cutaneous burn and smoke inhalation. Adult female sheep ( n = 18, 35.6 ± 1.0 kg) were divided into three groups following the injury: (1) sclerosis group: 1 h after injury, 4 mL of 70% ethanol was injected into Bronchial Artery via Bronchial catheter, n = 6; (2) control group: 1 h after injury, an equal dose of saline was injected into Bronchial Artery via the Bronchial catheter, n = 6; (3) sham group: no injury and no treatment, n = 6. The experiment was conducted in awake animals for 24 h. Results Bronchial blood flow, measured by microspheres, was significantly reduced after ethanol injection in the sclerosis group. Pulmonary function, evaluated by measurement of blood gas analysis, pulmonary mechanics, and pulmonary transvascular fluid flux, was severely impaired in the control group. However, pulmonary function was significantly improved by Bronchial Artery sclerosis. Conclusion The results of our study clearly demonstrate a crucial role of enhanced Bronchial circulation in thermal injury-related morbidity. Decreasing Bronchial circulation using pharmacological agents may be an effective strategy in management of burn patients with concomitant smoke inhalation injury.
-
a novel Bronchial Artery catheterization technique with preserved blood flow in an ovine model
Experimental Lung Research, 2010Co-Authors: Atsumori Hamahata, Perenlei Enkhbaatar, Matthias Lange, Motohiro Nozaki, Sakurai Hiroyuki, Naoki Morita, Yoshimitsu Nakano, L D Traber, Daniel L. TraberAbstract:The authors devised a novel Bronchial Artery catheterization technique to deliver agents directly into Bronchial circulation with preserved blood flow in an awake ovine model. A polyurethane catheter was inserted into Bronchial Artery via an incision into the 4th intercostal space. Regional blood flow of the airway was measured by fluorescent microspheres before cannulation, after cannulation, and 7 days after the operative procedure. The blood flows were also measured in a sham group (no cannulation, no ligation, n = 6), cannulation group (Bronchial Artery cannulation, n = 5), and ligation group (Bronchial Artery ligation, n = 5) at baseline and 6 hours after burn and smoke inhalation injury. The regional blood flows decreased slightly after cannulation in proximal bronchi, but recovered after 7 days. The regional blood flow increased 10-fold after inhalation injury in bronchi of the sham group. Bronchial Artery ligation significantly attenuated the increase of blood flow. However, cannulation preserved regional blood flow and did not prevent the blood flow increases after burn and smoke inhalation injury, thus constituting a novel Bronchial Artery catheterization technique.
