The Experts below are selected from a list of 1080 Experts worldwide ranked by ideXlab platform
Victor F. Tapson - One of the best experts on this subject based on the ideXlab platform.
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Lung Transplantation for Williams-Campbell Syndrome
Chest, 1998Co-Authors: Scott M. Palmer, Daniel T. Layish, Peter S. Kussin, Tim D. Oury, Robert D. Davis, Victor F. TapsonAbstract:Williams-Campbell syndrome is a rare disorder characterized by a deficiency of cartilage in subsegmental bronchi leading to distal airway collapse and bronchiectasis. We report the first case of lung transplantation in a patient with end-stage lung disease secondary to Williams-Campbell syndrome. Although the patient did not have proximal airway collapse prior to transplantation, his posttransplant course was complicated by the development of Bronchomalacia of the right and left mainstem bronchi. The patient experienced recurrent pulmonary infections and died of bacterial pneumonia 1 year after transplantation. Autopsy revealed cartilage deficiency in both right and left mainstem bronchi. A hypothesis may be made that a combination of proximal cartilage deficiency and posttransplant airway ischemia led to the development of Bronchomalacia after lung transplantation. Thus, in contrast to previous reports, the cartilage deficiency in Williams-Campbell syndrome can involve both proximal and distal airways. Consequently, bilateral sequential lung transplantation may not be an effective therapeutic option in patients with this syndrome.
Pieter E. Postmus - One of the best experts on this subject based on the ideXlab platform.
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Severe Bronchomalacia in a 65-year-old man treated with stent insertion instead of surgical bronchoplasty.
Diagnostic and therapeutic endoscopy, 1995Co-Authors: Tom G. Sutedja, Jan C. De Graaf, Franz M.n.h. Schramel, Klaas W. Van Kralingen, Pieter E. PostmusAbstract:Bronchomalacia in adults is rare. A case is reported here of a 65-year-old man with severe cough and mucostasis, caused by a benign Bronchomalacia of the ventral wall of the left main bronchus. This was treated successfully with the insertion of a silicone Dumon stent as an alternative to surgical bronchoplasty.
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Severe Bronchomalacia in a 65-Year-Old Man Treated With Stent Insertion Instead of Surgical Bronchoplasty
Hindawi Limited, 1995Co-Authors: Tom G. Sutedja, Jan C. De Graaf, Franz M.n.h. Schramel, Klaas W. Van Kralingen, Pieter E. PostmusAbstract:Bronchomalacia in adults is rare. A case is reported here of a 65-year-old man with severe cough and mucostasis, caused by a benign Bronchomalacia of the ventral wall of the left main bronchus. This was treated successfully with the insertion of a silicone Dumon stent as an alternative to surgical bronchoplasty
Scott M. Palmer - One of the best experts on this subject based on the ideXlab platform.
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Lung Transplantation for Williams-Campbell Syndrome
Chest, 1998Co-Authors: Scott M. Palmer, Daniel T. Layish, Peter S. Kussin, Tim D. Oury, Robert D. Davis, Victor F. TapsonAbstract:Williams-Campbell syndrome is a rare disorder characterized by a deficiency of cartilage in subsegmental bronchi leading to distal airway collapse and bronchiectasis. We report the first case of lung transplantation in a patient with end-stage lung disease secondary to Williams-Campbell syndrome. Although the patient did not have proximal airway collapse prior to transplantation, his posttransplant course was complicated by the development of Bronchomalacia of the right and left mainstem bronchi. The patient experienced recurrent pulmonary infections and died of bacterial pneumonia 1 year after transplantation. Autopsy revealed cartilage deficiency in both right and left mainstem bronchi. A hypothesis may be made that a combination of proximal cartilage deficiency and posttransplant airway ischemia led to the development of Bronchomalacia after lung transplantation. Thus, in contrast to previous reports, the cartilage deficiency in Williams-Campbell syndrome can involve both proximal and distal airways. Consequently, bilateral sequential lung transplantation may not be an effective therapeutic option in patients with this syndrome.
David J Hunter - One of the best experts on this subject based on the ideXlab platform.
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retrieving a malpositioned tracheobronchial stent utilizing amplatz gooseneck snare a case report
CardioVascular and Interventional Radiology, 2004Co-Authors: Baljendra S Kapoor, Greg Rathmann, Shawn Shrawny, Jordan M Dunitz, David J HunterAbstract:Tracheobronchial stents play a major role in the management of tracheobronchial stenoses and/or Bronchomalacia. A very few techniques have been described in literature to remove misplaced or malpositioned tracheobronchial stents. This is a case report describing a technique to retrieve a malpositioned stent utilizing Amplatz gooseneck snare.
Phillip M Boiselle - One of the best experts on this subject based on the ideXlab platform.
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Bronchial collapsibility at forced expiration in healthy volunteers: assessment with multidetector CT.
Radiology, 2010Co-Authors: Diana Litmanovich, Carl R. O'donnell, Alexander A. Bankier, Armin Ernst, Mary E. Millett, Stephen H. Loring, Phillip M BoiselleAbstract:We found that healthy individuals frequently exceed the current diagnostic criterion for Bronchomalacia, suggesting the need for a more rigorous diagnostic criterion to prevent overdiagnosis.
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excessive collapsibility of bronchi in bronchiectasis evaluation on volumetric expiratory high resolution ct
Journal of Computer Assisted Tomography, 2006Co-Authors: Mizuki Nishino, Bettina Siewert, David H Roberts, Shiva Gautam, Phillip M Boiselle, Vassilios Raptopoulos, Hiroto HatabuAbstract:Objective: To evaluate the frequency and severity of Bronchomalacia, defined as excessive collapsibility of bronchi, in bronchiectasis; to compare the extent of air trapping in bronchiectasis patients with/without Bronchomalacia; and to correlate the severity of Bronchomalacia and the extent of air trapping versus pulmonary function. Materials and Methods: Forty-six patients with bronchiectasis evaluated by volumetric expiratory high-resolution computed tomography (CT) and pulmonary function tests were studied. The presence and severity of Bronchomalacia were evaluated on contiguous axial high-resolution CT images using a 4-point scale. The extent of air trapping was graded on coronal reformations using a 5-point scale. Differences in the extent of air trapping in patients with/without Bronchomalacia and the correlation between the severity of Bronchomalacia and the extent of air trapping were investigated. The severity of Bronchomalacia and the extent of air trapping were correlated with pulmonary function. Results: Of 46 patients with bronchiectasis, 32 patients (70%) had Bronchomalacia. Air trapping was present in 43 patients (93%). The extent of air trapping in patients with Bronchomalacia was significantly greater compared with the patients without Bronchomalacia (P = 0.0308). The correlation between the severity of Bronchomalacia and extent of air trapping was not statistically significant (r s = 0.029, P = 0.8457). Conclusions: The extent of air trapping in bronchiectasis patients with Bronchomalacia was significantly greater compared with bronchiectasis patients without Bronchomalacia, suggesting that the Bronchomalacia is one of the underlying mechanisms of air trapping in bronchiectasis.
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Bronchomalacia in sarcoidosis: evaluation on volumetric expiratory high-resolution CT of the lung.
Academic radiology, 2005Co-Authors: Mizuki Nishino, David H Roberts, Phillip M Boiselle, Masaomi Kuroki, Yasutane Mori, Hiroto HatabuAbstract:Rationale and objectives The aim of this study is to investigate the frequency of Bronchomalacia associated with sarcoidosis and compare the extent of air trapping in patients with sarcoidosis with and without Bronchomalacia. Materials and methods Eighteen consecutive patients (6 men, 12 women; age, 29–64 years; mean age, 47 years) with pathologically proven sarcoidosis who underwent clinical volumetric expiratory high-resolution computed tomography were studied. On contiguous end-expiratory images, the presence and severity of Bronchomalacia and extent of air trapping were evaluated. The extent of air trapping was compared between patients with sarcoidosis with and without Bronchomalacia. Results Bronchomalacia was noted in 11 of 18 patients (61%) with sarcoidosis (grade 1 [mild], n = 6; grade 2 [moderate], n = 4; and grade 3 [severe], n = 1). Air trapping was observed in 17 of 18 patients (94%; grade 1 [1%–25%], n = 8; grade 2 [26%–50%], n = 9). The extent of air trapping in patients with Bronchomalacia was significantly greater than that in patients without Bronchomalacia (P = .027, chi-squared test). Conclusion Bronchomalacia frequently was associated with sarcoidosis, and the extent of air trapping was significantly greater in patients with sarcoidosis with Bronchomalacia compared with those without Bronchomalacia.
