The Experts below are selected from a list of 5961 Experts worldwide ranked by ideXlab platform
De Figueiredo - One of the best experts on this subject based on the ideXlab platform.
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highly aggressive Brown Tumor in the jaw associated with tertiary hyperparathyroidism
Pediatric Dentistry, 2006Co-Authors: L P Pinto, Fernanda Goncalves Salum, K Cherubinim, L S Yurgel, De FigueiredoAbstract:The purpose of this paper is to describe the case of a 12-year-old patient with end-stage chronic renal failure. The patient presented with an osteolytic lesion in the mandible with expansion of the buccal, lingual, and occlusal cortical bone, as well as dislocation of the teeth in the area. The calcium, creatinine, and parathormone (PTH) contents of the blood were elevated. A histopathological examination of the jaw lesion revealed the presence of a Brown Tumor lesion, which is associated with hyperparathyroidism (HPT). An adenoma was found in the upper left parathyroid, a fi nding compatible with the diagnosis of tertiary HPT. In spite of the continuous ambulatory peritoneal dialysis instituted, the osteolytic lesion kept on growing. A conservative treatment employing an association of intralesional corticosteroid and salmon calcitonin (inhaled) was carried out. After 14 months of therapy, a reduction in size and complete calcifi cation of the lesion were achieved. Aesthetic osteo- plasty of the jaw was then performed. (Pediatr Dent 2006;28:543-546)
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highly aggressive Brown Tumor in the jaw associated with tertiary hyperparathyroidism
Pediatric Dentistry, 2006Co-Authors: L P Pinto, Fernanda Goncalves Salum, K Cherubinim, L S Yurgel, De FigueiredoAbstract:The purpose of this paper is to describe the case of a 12-year-old patient with end-stage chronic renal failure. The patient presented with an osteolytic lesion in the mandible with expansion of the buccal, lingual, and occlusal cortical bone, as well as dislocation of the teeth in the area. The calcium, creatinine, and parathormone (PTH) contents of the blood were elevated. A histopathological examination of the jaw lesion revealed the presence of a Brown Tumor lesion, which is associated with hyperparathyroidism (HPT). An adenoma was found in the upper left parathyroid, a finding compatible with the diagnosis of tertiary HPT. In spite of the continuous ambulatory peritoneal dialysis instituted, the osteolytic lesion kept on growing. A conservative treatment employing an association of intralesional corticosteroid and salmon calcitonin (inhaled) was carried out. After 14 months of therapy, a reduction in size and complete calcification of the lesion were achieved. Aesthetic osteoplasty of the jaw was then performed.
Meng Hu - One of the best experts on this subject based on the ideXlab platform.
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humeral Brown Tumor as first presentation of primary hyperparathyroidism caused by ectopic parathyroid adenomas report of two cases and review of literature
International Journal of Clinical and Experimental Pathology, 2014Co-Authors: Xiqian Wang, Jie Zhang, Weijun Tian, Min Wang, Qing He, Xiaoyu Liang, Meng HuAbstract:Two cases of Brown Tumor of the humerus caused by ectopic parathyroid adenomas were presented, which to our knowledge has not been previously documented in the international literature. There are two highlights in these two cases. First, Brown Tumors of the long bones may commonly involve femur and tibia, rarely involve humerus in association with primary hyperparathyroidism. Second, ectopic parathyroid adenomas of our patient had an unusual location of this disorder. We explored the role of ultrasound, MIBI scintigraphy as well as FNAB (fine needle aspiration biopsy) in diagnosis of Brown Tumor especially simultaneously occurrence of ectopic parathyroid adenomas and the importance of a thorough diagnostic work-up. The contemporary diagnosis and treatment options will be emphasized.
Jehad Alwatban - One of the best experts on this subject based on the ideXlab platform.
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sphenoid sinus Brown Tumor of secondary hyperparathyroidism case report
Neurosurgery, 1998Co-Authors: Imad Kanaan, Mohammed Ahmed, Ayman Rifai, Jehad AlwatbanAbstract:OBJECTIVE AND IMPORTANCE: Brown Tumor is a misnomer for a reparative cellular process caused by primary or, less commonly, secondary or tertiary hyperparathyroidism. Atypical involvement of the base of the cranium in the area of the sphenoid sinus and the orbit is exceedingly rare and may produce a neurological deficit as a primary clinical presentation. Those neurosurgeons dealing with cranial base and pituitary lesions should be aware of this disease entity, and it should be listed in the differential diagnosis. CLINICAL PRESENTATION: A 21-year-old woman with end-stage renal failure on chronic dialysis was referred to the Department of Neurosciences at King Faisal Specialist Hospital and Research Centre with a 4-month history of progressive impairment of vision, associated with headache and nausea. Computed tomography and magnetic resonance imaging demonstrated an expansive mass lesion in the sphenoid sinus with erosion of the sellar floor and posterior medial wall of the orbit causing compression of the optic nerves. The biochemical laboratory studies showed elevation of parathyroid hormone and confirmed the diagnosis of hyperparathyroidism. INTERVENTION: The transnasal-transsphenoidal approach was used for extensive microsurgical removal of the lesion. The postoperative course was uneventful, and the improvement in vision was dramatic. CONCLUSION: Brown Tumor, although rare, should be listed in the differential diagnosis of expansive mass lesions in the area of the sphenoid sinus and cranial base. The management is multidisciplinary, and therapeutic options should target the underlying cause.
L P Pinto - One of the best experts on this subject based on the ideXlab platform.
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highly aggressive Brown Tumor in the jaw associated with tertiary hyperparathyroidism
Pediatric Dentistry, 2006Co-Authors: L P Pinto, Fernanda Goncalves Salum, K Cherubinim, L S Yurgel, De FigueiredoAbstract:The purpose of this paper is to describe the case of a 12-year-old patient with end-stage chronic renal failure. The patient presented with an osteolytic lesion in the mandible with expansion of the buccal, lingual, and occlusal cortical bone, as well as dislocation of the teeth in the area. The calcium, creatinine, and parathormone (PTH) contents of the blood were elevated. A histopathological examination of the jaw lesion revealed the presence of a Brown Tumor lesion, which is associated with hyperparathyroidism (HPT). An adenoma was found in the upper left parathyroid, a fi nding compatible with the diagnosis of tertiary HPT. In spite of the continuous ambulatory peritoneal dialysis instituted, the osteolytic lesion kept on growing. A conservative treatment employing an association of intralesional corticosteroid and salmon calcitonin (inhaled) was carried out. After 14 months of therapy, a reduction in size and complete calcifi cation of the lesion were achieved. Aesthetic osteo- plasty of the jaw was then performed. (Pediatr Dent 2006;28:543-546)
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highly aggressive Brown Tumor in the jaw associated with tertiary hyperparathyroidism
Pediatric Dentistry, 2006Co-Authors: L P Pinto, Fernanda Goncalves Salum, K Cherubinim, L S Yurgel, De FigueiredoAbstract:The purpose of this paper is to describe the case of a 12-year-old patient with end-stage chronic renal failure. The patient presented with an osteolytic lesion in the mandible with expansion of the buccal, lingual, and occlusal cortical bone, as well as dislocation of the teeth in the area. The calcium, creatinine, and parathormone (PTH) contents of the blood were elevated. A histopathological examination of the jaw lesion revealed the presence of a Brown Tumor lesion, which is associated with hyperparathyroidism (HPT). An adenoma was found in the upper left parathyroid, a finding compatible with the diagnosis of tertiary HPT. In spite of the continuous ambulatory peritoneal dialysis instituted, the osteolytic lesion kept on growing. A conservative treatment employing an association of intralesional corticosteroid and salmon calcitonin (inhaled) was carried out. After 14 months of therapy, a reduction in size and complete calcification of the lesion were achieved. Aesthetic osteoplasty of the jaw was then performed.
Xiqian Wang - One of the best experts on this subject based on the ideXlab platform.
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humeral Brown Tumor as first presentation of primary hyperparathyroidism caused by ectopic parathyroid adenomas report of two cases and review of literature
International Journal of Clinical and Experimental Pathology, 2014Co-Authors: Xiqian Wang, Jie Zhang, Weijun Tian, Min Wang, Qing He, Xiaoyu Liang, Meng HuAbstract:Two cases of Brown Tumor of the humerus caused by ectopic parathyroid adenomas were presented, which to our knowledge has not been previously documented in the international literature. There are two highlights in these two cases. First, Brown Tumors of the long bones may commonly involve femur and tibia, rarely involve humerus in association with primary hyperparathyroidism. Second, ectopic parathyroid adenomas of our patient had an unusual location of this disorder. We explored the role of ultrasound, MIBI scintigraphy as well as FNAB (fine needle aspiration biopsy) in diagnosis of Brown Tumor especially simultaneously occurrence of ectopic parathyroid adenomas and the importance of a thorough diagnostic work-up. The contemporary diagnosis and treatment options will be emphasized.
