The Experts below are selected from a list of 312 Experts worldwide ranked by ideXlab platform
Esko Alhava - One of the best experts on this subject based on the ideXlab platform.
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dielectric measurement in experimental burns a new tool for burn depth determination
Plastic and Reconstructive Surgery, 2006Co-Authors: Anthony Papp, Tapani Lahtinen, Mikko Harma, Jouni Nuutinen, Esko AlhavaAbstract:Background: There has been a lack of methods to provide quantitative information of local tissue edema after burn injury. Noninvasive dielectric measurements provide this information. The measured value, the dielectric constant, is directly related to the amount of water in tissue. Using probes of different sizes, the measurements give information from different tissue depths. The aim of this study was to characterize edema formation at different tissue depths and to examine whether the dielectric measurements could be used to distinguish partial- and full-thickness burns in pigs. Methods: An experimental animal study with pigs (n = 6) was performed in which dielectric measurements were taken of superficial, partial-thickness, and full-thickness burns for 72 hours. Results: There was an increase in tissue water content in the superficial dermis in the partial-thickness bums at 48 hours. In whole dermis, the superficial bums resulted in increased tissue water content at 8 hours, and the partial-thickness bums resulted in increased tissue water content at 8, 24, and 72 hours. In deep bums, the water content was significantly decreased in the superficial dermis at 24 hours. All burns resulted in a considerable increase in fat water content. The dielectric probes could be used to differentiate partial- and full-thickness bums as early as 8 hours after bum. Receiver operating curve analysis of the measurements indicated 70 to 90 percent sensitivity and 80 to 100 percent specificity after 8 hours. Conclusions: The dielectric measurements provide a sensitive and noninvasive method for examining tissue edema and differentiate partial- and fall-thickness bums in experimental bums. Thus, they are of clinical interest for early burn depth determination.
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Dielectric measurement in experimental burns: a new tool for burn depth determination?
Plastic and reconstructive surgery, 2006Co-Authors: Anthony Papp, Tapani Lahtinen, Mikko Harma, Ari Uusaro, Jouni Nuutinen, Esko AlhavaAbstract:There has been a lack of methods to provide quantitative information of local tissue edema after burn injury. Noninvasive dielectric measurements provide this information. The measured value, the dielectric constant, is directly related to the amount of water in tissue. Using probes of different sizes, the measurements give information from different tissue depths. The aim of this study was to characterize edema formation at different tissue depths and to examine whether the dielectric measurements could be used to distinguish partial- and full-thickness burns in pigs. An experimental animal study with pigs (n = 6) was performed in which dielectric measurements were taken of superficial, partial-thickness, and full-thickness burns for 72 hours. There was an increase in tissue water content in the superficial dermis in the partial-thickness burns at 48 hours. In whole dermis, the superficial burns resulted in increased tissue water content at 8 hours, and the partial-thickness burns resulted in increased tissue water content at 8, 24, and 72 hours. In deep burns, the water content was significantly decreased in the superficial dermis at 24 hours. All burns resulted in a considerable increase in fat water content. The dielectric probes could be used to differentiate partial- and full-thickness burns as early as 8 hours after burn. Receiver operating curve analysis of the measurements indicated 70 to 90 percent sensitivity and 80 to 100 percent specificity after 8 hours. The dielectric measurements provide a sensitive and noninvasive method for examining tissue edema and differentiate partial- and full-thickness burns in experimental burns. Thus, they are of clinical interest for early burn depth determination.
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the progression of burn depth in experimental burns a histological and methodological study
Burns, 2004Co-Authors: Anthony Papp, Tapani Lahtinen, Kálmán Király, Mikko Harma, Ari Uusaro, Esko AlhavaAbstract:This study was designed to create a reproducible model for experimental burn wound research in pigs. Previously, the thicker paraspinal skin has been used. We used the more human-like ventral skin to create burns of different depths. Contact burns were created to 11 pigs using a brass plate heated to 100 ◦ C in boiling water. Different contact times were used to create burns of different depths. In pigs 1–6, the follow-up time was 72 h and in pigs 7–11 24 h. Burn depth was determined by histology. Histologically, samples were classified into five anatomical layers: epidermis, upper one-third of the dermis, middle third of the dermis, deepest third of the dermis and subcutaneous fat. The location of both thromboses and burn marks were evaluated, respectively. The 1 s contact time lead to a superficial thermal injury, 3 s to a partial thickness and 9 s to a full thickness injury. A progression of burn depth was found until 48 h post-injury. The intra-observer correlation after repeated histological analyses of burn depths by the same histopathologist and the repeatability of burn depth creation yielded kappa coefficients 0.83 and 0.92, respectively. Conclusion: a reproducible burn model for further research purposes was obtained. © 2004 Elsevier Ltd and ISBI. All rights reserved.
Ingrid Steinvall - One of the best experts on this subject based on the ideXlab platform.
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Validation of the burn intervention score in a National Burn Centre.
Burns, 2018Co-Authors: Islam Abdelrahman, Moustafa Elmasry, Mats Fredrikson, Ingrid SteinvallAbstract:The Linkoping burn score has been used for two decades to calculate the cost to the hospital of each burned patient. Our aim was to validate the Burn Score in a dedicated Burn Centre by analysing t ...
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Validation of the burn intervention score in a National Burn Centre.
Burns : journal of the International Society for Burn Injuries, 2018Co-Authors: Islam Abdelrahman, Moustafa Elmasry, Mats Fredrikson, Ingrid SteinvallAbstract:The Linkoping burn score has been used for two decades to calculate the cost to the hospital of each burned patient. Our aim was to validate the Burn Score in a dedicated Burn Centre by analysing the associations with burn-specific factors: percentage of total body surface area burned (TBSA%), cause of injury, patients referred from other (non-specialist) centres, and survival, to find out which of these factors resulted in higher scores. Our second aim was to analyse the variation in scores of each category of care (surveillance, respiration, circulation, wound care, mobilisation, laboratory tests, infusions, and operation). We made a retrospective analysis of all burned patients admitted during the period 2000-15. Multivariable regression models were used to analyse predictive factors for an increased daily burn score, the cumulative burn score (the sum of the daily burn scores for each patient) and the total burn score (total sum of burn scores for the whole group throughout the study period) in addition to sub-analysis of the different categories of care that make up the burn score. We retrieved 22301 daily recordings for inpatients. Mobilisation and care of the wound accounted for more than half of the total burn score during the study. Increased TBSA% and age over 45 years were associated with increased cumulative (model R2 0.43, p
Anthony Papp - One of the best experts on this subject based on the ideXlab platform.
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dielectric measurement in experimental burns a new tool for burn depth determination
Plastic and Reconstructive Surgery, 2006Co-Authors: Anthony Papp, Tapani Lahtinen, Mikko Harma, Jouni Nuutinen, Esko AlhavaAbstract:Background: There has been a lack of methods to provide quantitative information of local tissue edema after burn injury. Noninvasive dielectric measurements provide this information. The measured value, the dielectric constant, is directly related to the amount of water in tissue. Using probes of different sizes, the measurements give information from different tissue depths. The aim of this study was to characterize edema formation at different tissue depths and to examine whether the dielectric measurements could be used to distinguish partial- and full-thickness burns in pigs. Methods: An experimental animal study with pigs (n = 6) was performed in which dielectric measurements were taken of superficial, partial-thickness, and full-thickness burns for 72 hours. Results: There was an increase in tissue water content in the superficial dermis in the partial-thickness bums at 48 hours. In whole dermis, the superficial bums resulted in increased tissue water content at 8 hours, and the partial-thickness bums resulted in increased tissue water content at 8, 24, and 72 hours. In deep bums, the water content was significantly decreased in the superficial dermis at 24 hours. All burns resulted in a considerable increase in fat water content. The dielectric probes could be used to differentiate partial- and full-thickness bums as early as 8 hours after bum. Receiver operating curve analysis of the measurements indicated 70 to 90 percent sensitivity and 80 to 100 percent specificity after 8 hours. Conclusions: The dielectric measurements provide a sensitive and noninvasive method for examining tissue edema and differentiate partial- and fall-thickness bums in experimental bums. Thus, they are of clinical interest for early burn depth determination.
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Dielectric measurement in experimental burns: a new tool for burn depth determination?
Plastic and reconstructive surgery, 2006Co-Authors: Anthony Papp, Tapani Lahtinen, Mikko Harma, Ari Uusaro, Jouni Nuutinen, Esko AlhavaAbstract:There has been a lack of methods to provide quantitative information of local tissue edema after burn injury. Noninvasive dielectric measurements provide this information. The measured value, the dielectric constant, is directly related to the amount of water in tissue. Using probes of different sizes, the measurements give information from different tissue depths. The aim of this study was to characterize edema formation at different tissue depths and to examine whether the dielectric measurements could be used to distinguish partial- and full-thickness burns in pigs. An experimental animal study with pigs (n = 6) was performed in which dielectric measurements were taken of superficial, partial-thickness, and full-thickness burns for 72 hours. There was an increase in tissue water content in the superficial dermis in the partial-thickness burns at 48 hours. In whole dermis, the superficial burns resulted in increased tissue water content at 8 hours, and the partial-thickness burns resulted in increased tissue water content at 8, 24, and 72 hours. In deep burns, the water content was significantly decreased in the superficial dermis at 24 hours. All burns resulted in a considerable increase in fat water content. The dielectric probes could be used to differentiate partial- and full-thickness burns as early as 8 hours after burn. Receiver operating curve analysis of the measurements indicated 70 to 90 percent sensitivity and 80 to 100 percent specificity after 8 hours. The dielectric measurements provide a sensitive and noninvasive method for examining tissue edema and differentiate partial- and full-thickness burns in experimental burns. Thus, they are of clinical interest for early burn depth determination.
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the progression of burn depth in experimental burns a histological and methodological study
Burns, 2004Co-Authors: Anthony Papp, Tapani Lahtinen, Kálmán Király, Mikko Harma, Ari Uusaro, Esko AlhavaAbstract:This study was designed to create a reproducible model for experimental burn wound research in pigs. Previously, the thicker paraspinal skin has been used. We used the more human-like ventral skin to create burns of different depths. Contact burns were created to 11 pigs using a brass plate heated to 100 ◦ C in boiling water. Different contact times were used to create burns of different depths. In pigs 1–6, the follow-up time was 72 h and in pigs 7–11 24 h. Burn depth was determined by histology. Histologically, samples were classified into five anatomical layers: epidermis, upper one-third of the dermis, middle third of the dermis, deepest third of the dermis and subcutaneous fat. The location of both thromboses and burn marks were evaluated, respectively. The 1 s contact time lead to a superficial thermal injury, 3 s to a partial thickness and 9 s to a full thickness injury. A progression of burn depth was found until 48 h post-injury. The intra-observer correlation after repeated histological analyses of burn depths by the same histopathologist and the repeatability of burn depth creation yielded kappa coefficients 0.83 and 0.92, respectively. Conclusion: a reproducible burn model for further research purposes was obtained. © 2004 Elsevier Ltd and ISBI. All rights reserved.
Islam Abdelrahman - One of the best experts on this subject based on the ideXlab platform.
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Validation of the burn intervention score in a National Burn Centre.
Burns, 2018Co-Authors: Islam Abdelrahman, Moustafa Elmasry, Mats Fredrikson, Ingrid SteinvallAbstract:The Linkoping burn score has been used for two decades to calculate the cost to the hospital of each burned patient. Our aim was to validate the Burn Score in a dedicated Burn Centre by analysing t ...
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Validation of the burn intervention score in a National Burn Centre.
Burns : journal of the International Society for Burn Injuries, 2018Co-Authors: Islam Abdelrahman, Moustafa Elmasry, Mats Fredrikson, Ingrid SteinvallAbstract:The Linkoping burn score has been used for two decades to calculate the cost to the hospital of each burned patient. Our aim was to validate the Burn Score in a dedicated Burn Centre by analysing the associations with burn-specific factors: percentage of total body surface area burned (TBSA%), cause of injury, patients referred from other (non-specialist) centres, and survival, to find out which of these factors resulted in higher scores. Our second aim was to analyse the variation in scores of each category of care (surveillance, respiration, circulation, wound care, mobilisation, laboratory tests, infusions, and operation). We made a retrospective analysis of all burned patients admitted during the period 2000-15. Multivariable regression models were used to analyse predictive factors for an increased daily burn score, the cumulative burn score (the sum of the daily burn scores for each patient) and the total burn score (total sum of burn scores for the whole group throughout the study period) in addition to sub-analysis of the different categories of care that make up the burn score. We retrieved 22301 daily recordings for inpatients. Mobilisation and care of the wound accounted for more than half of the total burn score during the study. Increased TBSA% and age over 45 years were associated with increased cumulative (model R2 0.43, p
Lennart Weitgasser - One of the best experts on this subject based on the ideXlab platform.
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analysis of the microcirculation after soft tissue reconstruction of the outer ear with burns in patients with severe burn injuries
Journal of Plastic Reconstructive and Aesthetic Surgery, 2016Co-Authors: Fabian Medved, Jens Rothenberger, Raluca Medesan, Lennart Weitgasser, Theodora Manoli, Aline Naumann, Thomas Schoeller, Hans-eberhard SchallerAbstract:Summary Reconstruction of soft tissue defects of the ear with burns remains one of the most difficult tasks for the reconstructive surgeon. Although numerous reconstructive options are available, the results are often unpredictable and worse than expected. Besides full and split skin grafting, local random pattern flaps and pedicled flaps are frequently utilized to cover soft tissue defects of the outer auricle. Because of the difficulty and unpredictable nature of outer ear reconstruction after burn injury, a case–control study was conducted to determine the best reconstructive approach. The microcirculatory properties of different types of soft tissue reconstruction of the outer ear with burns in six severely burned Caucasian patients (three men and three women; mean age, 46 years (range, 22–70)) were compared to those in the healthy tissue of the outer ear using the O2C device (Oxygen to See; LEA Medizintechnik, Giesen, Germany). The results of this study revealed that the investigated microcirculation parameters such as the median values of blood flow (control group: 126 AU), relative amount of hemoglobin (control group: 59.5 AU), and tissue oxygen saturation (control group: 73%) are most similar to those of normal ear tissue when pedicled flaps based on the superficial temporal artery were used. These findings suggest that this type of reconstruction is superior for soft tissue reconstruction of the outer ear with burns in contrast to random pattern flaps and full skin grafts regarding the microcirculatory aspects. These findings may improve the knowledge on soft tissue viability and facilitate the exceptional and delicate process of planning the reconstruction of the auricle with burns.
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analysis of the microcirculation after soft tissue reconstruction of the outer ear with burns in patients with severe burn injuries
Journal of Plastic Reconstructive and Aesthetic Surgery, 2016Co-Authors: Fabian Medved, Jens Rothenberger, Raluca Medesan, Lennart Weitgasser, Theodora Manoli, Aline Naumann, Thomas Schoeller, Hans-eberhard SchallerAbstract:Summary Reconstruction of soft tissue defects of the ear with burns remains one of the most difficult tasks for the reconstructive surgeon. Although numerous reconstructive options are available, the results are often unpredictable and worse than expected. Besides full and split skin grafting, local random pattern flaps and pedicled flaps are frequently utilized to cover soft tissue defects of the outer auricle. Because of the difficulty and unpredictable nature of outer ear reconstruction after burn injury, a case–control study was conducted to determine the best reconstructive approach. The microcirculatory properties of different types of soft tissue reconstruction of the outer ear with burns in six severely burned Caucasian patients (three men and three women; mean age, 46 years (range, 22–70)) were compared to those in the healthy tissue of the outer ear using the O2C device (Oxygen to See; LEA Medizintechnik, Giesen, Germany). The results of this study revealed that the investigated microcirculation parameters such as the median values of blood flow (control group: 126 AU), relative amount of hemoglobin (control group: 59.5 AU), and tissue oxygen saturation (control group: 73%) are most similar to those of normal ear tissue when pedicled flaps based on the superficial temporal artery were used. These findings suggest that this type of reconstruction is superior for soft tissue reconstruction of the outer ear with burns in contrast to random pattern flaps and full skin grafts regarding the microcirculatory aspects. These findings may improve the knowledge on soft tissue viability and facilitate the exceptional and delicate process of planning the reconstruction of the auricle with burns.
