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Sirpa Vilska - One of the best experts on this subject based on the ideXlab platform.

  • five years of single embryo transfer with anonymous and non anonymous oocyte donation
    Reproductive Biomedicine Online, 2007
    Co-Authors: Viveca Soderstromanttila, Sirpa Vilska
    Abstract:

    Abstract Single embryo transfer (SET) has been the main embryo transfer strategy in the oocyte donation programme at the authors' clinic since 2000. The primary aim of this study was to evaluate the effect of SET on the clinical outcome in an unselected group of oocyte recipients. A retrospective analysis of the outcome in 142 recipient cycles (116 from anonymous donors; 26 from known donors) was performed. The oocytes from each anonymous donor were shared between two recipients if at least 10 oocytes were obtained. The proportion of SET of all fresh transfers was 77.3%. The clinical pregnancy rate (CPR) was 43.2% and the delivery rate 31.1% per embryo transfer. The outcome was similar in recipients undergoing anonymous and non-anonymous donation. The delivery rates were similar after SET (30.4%) or double embryo transfer (DET) (33.3%), whereas the twin rate was 0% after SET and 40% after DET. The implantation rate was significantly better ( P

Anna Veiga - One of the best experts on this subject based on the ideXlab platform.

  • elective single embryo transfer in oocyte donation programmes should it be the rule
    Reproductive Biomedicine Online, 2012
    Co-Authors: Elisabet Clua, Buenaventura Coroleu, Montse Boada, I Rodriguez, Pedro N Barri, Anna Veiga
    Abstract:

    Abstract The aim of this study is to compare the cumulative clinical pregnancy and live birth rates (fresh embryo transfers followed by frozen–thawed embryo transfers from the same stimulated cycle) between single-embryo transfer (SET) and double-embryo transfer (DET) in an oocyte donation programme. A retrospective analysis of the outcome in 1139 recipient fresh cycles (1073 from DET and 66 from SET) with at least three available embryos for transfer was performed. The clinical pregnancy rates were similar after SET (45.5%, 30/66) and DET (57.1%, 613/1073), whereas the multiple pregnancy rate was 0% and 39.5% for SET and DET, respectively. After evaluating the results using the Kaplan–Meier survival analysis in a period of 1 year, no statistically significant differences were observed in the cumulative clinical pregnancy and live birth rates (SET 82.8% and 76.4% versus DET 77.2% and 63.7%). The results indicate that for women who have at least three available embryos in oocyte donation programmes, one single embryo should be transferred as no significant decrease in the success rate is observed and multiple pregnancy can be avoided. Clinical pregnancy rate is higher when transferring two embryos compared with one. However, this also results in a higher incidence of twin pregnancy, which is associated with increased obstetric and perinatal risks. The aim of this study was to compare the cumulative clinical pregnancy and live birth rates (fresh embryo transfers followed by frozen–thawed embryo transfers from the same stimulated cycle) between single-embryo transfer (SET) and double-embryo transfer (DET) cycles in our oocyte donation programme. A retrospective analysis of the outcome in 1139 recipient fresh cycles (1076 from DET and 66 from SET) with at least three available embryos for transfer was performed. The clinical pregnancy rates were similar after SET (45.5%, 30/66) and DET (57.1%, 613/1073), whereas the multiple pregnancy rate was 0% and 39.5% for SET and DET, respectively. The cumulative clinical pregnancy and live birth rates were similar between the two strategies (SET 82.8% versus DET 77.2%) and the same was found for the cumulative live birth rates (SET 76.4% versus DET 63.7%). Our results indicate that for women who have at least three available embryos in OD programmes, one single embryo should be transferred as no significant decrease in the success rate is observed while multiple pregnancy is avoided.

Viveca Soderstromanttila - One of the best experts on this subject based on the ideXlab platform.

  • five years of single embryo transfer with anonymous and non anonymous oocyte donation
    Reproductive Biomedicine Online, 2007
    Co-Authors: Viveca Soderstromanttila, Sirpa Vilska
    Abstract:

    Abstract Single embryo transfer (SET) has been the main embryo transfer strategy in the oocyte donation programme at the authors' clinic since 2000. The primary aim of this study was to evaluate the effect of SET on the clinical outcome in an unselected group of oocyte recipients. A retrospective analysis of the outcome in 142 recipient cycles (116 from anonymous donors; 26 from known donors) was performed. The oocytes from each anonymous donor were shared between two recipients if at least 10 oocytes were obtained. The proportion of SET of all fresh transfers was 77.3%. The clinical pregnancy rate (CPR) was 43.2% and the delivery rate 31.1% per embryo transfer. The outcome was similar in recipients undergoing anonymous and non-anonymous donation. The delivery rates were similar after SET (30.4%) or double embryo transfer (DET) (33.3%), whereas the twin rate was 0% after SET and 40% after DET. The implantation rate was significantly better ( P

Elisabet Clua - One of the best experts on this subject based on the ideXlab platform.

  • elective single embryo transfer in oocyte donation programmes should it be the rule
    Reproductive Biomedicine Online, 2012
    Co-Authors: Elisabet Clua, Buenaventura Coroleu, Montse Boada, I Rodriguez, Pedro N Barri, Anna Veiga
    Abstract:

    Abstract The aim of this study is to compare the cumulative clinical pregnancy and live birth rates (fresh embryo transfers followed by frozen–thawed embryo transfers from the same stimulated cycle) between single-embryo transfer (SET) and double-embryo transfer (DET) in an oocyte donation programme. A retrospective analysis of the outcome in 1139 recipient fresh cycles (1073 from DET and 66 from SET) with at least three available embryos for transfer was performed. The clinical pregnancy rates were similar after SET (45.5%, 30/66) and DET (57.1%, 613/1073), whereas the multiple pregnancy rate was 0% and 39.5% for SET and DET, respectively. After evaluating the results using the Kaplan–Meier survival analysis in a period of 1 year, no statistically significant differences were observed in the cumulative clinical pregnancy and live birth rates (SET 82.8% and 76.4% versus DET 77.2% and 63.7%). The results indicate that for women who have at least three available embryos in oocyte donation programmes, one single embryo should be transferred as no significant decrease in the success rate is observed and multiple pregnancy can be avoided. Clinical pregnancy rate is higher when transferring two embryos compared with one. However, this also results in a higher incidence of twin pregnancy, which is associated with increased obstetric and perinatal risks. The aim of this study was to compare the cumulative clinical pregnancy and live birth rates (fresh embryo transfers followed by frozen–thawed embryo transfers from the same stimulated cycle) between single-embryo transfer (SET) and double-embryo transfer (DET) cycles in our oocyte donation programme. A retrospective analysis of the outcome in 1139 recipient fresh cycles (1076 from DET and 66 from SET) with at least three available embryos for transfer was performed. The clinical pregnancy rates were similar after SET (45.5%, 30/66) and DET (57.1%, 613/1073), whereas the multiple pregnancy rate was 0% and 39.5% for SET and DET, respectively. The cumulative clinical pregnancy and live birth rates were similar between the two strategies (SET 82.8% versus DET 77.2%) and the same was found for the cumulative live birth rates (SET 76.4% versus DET 63.7%). Our results indicate that for women who have at least three available embryos in OD programmes, one single embryo should be transferred as no significant decrease in the success rate is observed while multiple pregnancy is avoided.

Kazushige Terui - One of the best experts on this subject based on the ideXlab platform.

  • Light Affine Set Theory: A Naive Set Theory of Polynomial Time
    Studia Logica, 2004
    Co-Authors: Kazushige Terui
    Abstract:

    In [7], a naive set theory is introduced based on a polynomial time logical system, Light Linear Logic ( LLL ). Although it is reasonably claimed that the set theory inherits the intrinsically polytime character from the underlying logic LLL , the discussion there is largely informal, and a formal justification of the claim is not provided sufficiently. Moreover, the syntax is quite complicated in that it is based on a non-traditional hybrid sequent calculus which is required for formulating LLL . In this paper, we consider a naive set theory based on Intuitionistic Light Affine Logic ( ILAL ), a simplification of LLL introduced by [1], and call it Light Affine Set Theory ( LAST ). The simplicity of LAST allows us to rigorously verify its polytime character. In particular, we prove that a function over {0, 1}* is computable in polynomial time if and only if it is provably total in LAST .

  • Light Affine Set Theory: A Naive Set Theory of Polynomial Time
    Studia Logica, 2004
    Co-Authors: Kazushige Terui
    Abstract:

    In [7], a naive set theory is introduced based on a polynomial time logical system, Light Linear Logic (LLL). Although it is reasonably claimed that the set theory inherits the intrinsically polytime character from the underlying logic LLL, the discussion there is largely informal, and a formal justification of the claim is not provided sufficiently. Moreover, the syntax is quite complicated in that it is based on a non-traditional hybrid sequent calculus which is required for formulating LLL.