The Experts below are selected from a list of 2214 Experts worldwide ranked by ideXlab platform
M. Baghestanian - One of the best experts on this subject based on the ideXlab platform.
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Ultrasound Therapy for Calcific Tendinitis of the Shoulder
The New England journal of medicine, 1999Co-Authors: Gerold Ebenbichler, C. B. Erdogmus, K. L. Resch, M. A. Funovics, Franz Kainberger, G. Barisani, Martin Aringer, Peter Nicolakis, Günther F. Wiesinger, M. BaghestanianAbstract:Background and Methods Although ultrasound therapy is used to treat Calcific Tendinitis of the shoulder, its efficacy has not been rigorously evaluated. We conducted a randomized, double-blind comparison of ultrasonography and sham insonation in patients with symptomatic Calcific Tendinitis verified by radiography. Patients were assigned to receive 24 15-minute sessions of either pulsed ultrasound (frequency, 0.89 MHz; intensity, 2.5 W per square centimeter; pulsed mode, 1:4) or an indistinguishable sham treatment to the area over the Calcification. The first 15 treatments were given daily (five times per week), and the remainder were given three times a week for three weeks. Randomization was conducted according to shoulders rather than patients, so a patient with bilateral Tendinitis might receive either or both therapies. Results We enrolled 63 consecutive patients (70 shoulders). Fifty-four patients (61 shoulders) completed the study. There were 32 shoulders in the ultrasound-treatment group and 29 in...
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ultrasound therapy for Calcific Tendinitis of the shoulder
The New England Journal of Medicine, 1999Co-Authors: Gerold Ebenbichler, C. B. Erdogmus, K. L. Resch, M. A. Funovics, Franz Kainberger, G. Barisani, Martin Aringer, Peter Nicolakis, Günther F. Wiesinger, M. BaghestanianAbstract:BACKGROUND AND METHODS: Although ultrasound therapy is used to treat Calcific Tendinitis of the shoulder, its efficacy has not been rigorously evaluated. We conducted a randomized, double-blind comparison of ultrasonography and sham insonation in patients with symptomatic Calcific Tendinitis verified by radiography. Patients were assigned to receive 24 15-minute sessions of either pulsed ultrasound (frequency, 0.89 MHz; intensity, 2.5 W per square centimeter; pulsed mode, 1:4) or an indistinguishable sham treatment to the area over the Calcification. The first 15 treatments were given daily (five times per week), and the remainder were given three times a week for three weeks. Randomization was conducted according to shoulders rather than patients, so a patient with bilateral Tendinitis might receive either or both therapies. RESULTS: We enrolled 63 consecutive patients (70 shoulders). Fifty-four patients (61 shoulders) completed the study. There were 32 shoulders in the ultrasound-treatment group and 29 in the sham-treatment group. After six weeks of treatment, calcium deposits had resolved in six shoulders (19 percent) in the ultrasound-treatment group and decreased by at least 50 percent in nine shoulders (28 percent), as compared with respective values of zero and three (10 percent) in the sham-treatment group (P=0.003). At the nine-month follow-up visit, calcium deposits had resolved in 13 shoulders (42 percent) in the ultrasound-treatment group and improved in 7 shoulders (23 percent), as compared with respective values of 2 (8 percent) and 3 (12 percent) in the sham-treatment group (P=0.002). At the end of treatment, patients who had received ultrasound treatment had greater decreases in pain and greater improvements in the quality of life than those who had received sham treatment; at nine months, the differences between the groups were no longer significant. CONCLUSIONS: In patients with symptomatic Calcific Tendinitis of the shoulder, ultrasound treatment helps resolve Calcifications and is associated with short-term clinical improvement.
Gerold Ebenbichler - One of the best experts on this subject based on the ideXlab platform.
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Ultrasound Therapy for Calcific Tendinitis of the Shoulder
The New England journal of medicine, 1999Co-Authors: Gerold Ebenbichler, C. B. Erdogmus, K. L. Resch, M. A. Funovics, Franz Kainberger, G. Barisani, Martin Aringer, Peter Nicolakis, Günther F. Wiesinger, M. BaghestanianAbstract:Background and Methods Although ultrasound therapy is used to treat Calcific Tendinitis of the shoulder, its efficacy has not been rigorously evaluated. We conducted a randomized, double-blind comparison of ultrasonography and sham insonation in patients with symptomatic Calcific Tendinitis verified by radiography. Patients were assigned to receive 24 15-minute sessions of either pulsed ultrasound (frequency, 0.89 MHz; intensity, 2.5 W per square centimeter; pulsed mode, 1:4) or an indistinguishable sham treatment to the area over the Calcification. The first 15 treatments were given daily (five times per week), and the remainder were given three times a week for three weeks. Randomization was conducted according to shoulders rather than patients, so a patient with bilateral Tendinitis might receive either or both therapies. Results We enrolled 63 consecutive patients (70 shoulders). Fifty-four patients (61 shoulders) completed the study. There were 32 shoulders in the ultrasound-treatment group and 29 in...
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ultrasound therapy for Calcific Tendinitis of the shoulder
The New England Journal of Medicine, 1999Co-Authors: Gerold Ebenbichler, C. B. Erdogmus, K. L. Resch, M. A. Funovics, Franz Kainberger, G. Barisani, Martin Aringer, Peter Nicolakis, Günther F. Wiesinger, M. BaghestanianAbstract:BACKGROUND AND METHODS: Although ultrasound therapy is used to treat Calcific Tendinitis of the shoulder, its efficacy has not been rigorously evaluated. We conducted a randomized, double-blind comparison of ultrasonography and sham insonation in patients with symptomatic Calcific Tendinitis verified by radiography. Patients were assigned to receive 24 15-minute sessions of either pulsed ultrasound (frequency, 0.89 MHz; intensity, 2.5 W per square centimeter; pulsed mode, 1:4) or an indistinguishable sham treatment to the area over the Calcification. The first 15 treatments were given daily (five times per week), and the remainder were given three times a week for three weeks. Randomization was conducted according to shoulders rather than patients, so a patient with bilateral Tendinitis might receive either or both therapies. RESULTS: We enrolled 63 consecutive patients (70 shoulders). Fifty-four patients (61 shoulders) completed the study. There were 32 shoulders in the ultrasound-treatment group and 29 in the sham-treatment group. After six weeks of treatment, calcium deposits had resolved in six shoulders (19 percent) in the ultrasound-treatment group and decreased by at least 50 percent in nine shoulders (28 percent), as compared with respective values of zero and three (10 percent) in the sham-treatment group (P=0.003). At the nine-month follow-up visit, calcium deposits had resolved in 13 shoulders (42 percent) in the ultrasound-treatment group and improved in 7 shoulders (23 percent), as compared with respective values of 2 (8 percent) and 3 (12 percent) in the sham-treatment group (P=0.002). At the end of treatment, patients who had received ultrasound treatment had greater decreases in pain and greater improvements in the quality of life than those who had received sham treatment; at nine months, the differences between the groups were no longer significant. CONCLUSIONS: In patients with symptomatic Calcific Tendinitis of the shoulder, ultrasound treatment helps resolve Calcifications and is associated with short-term clinical improvement.
Andrew Carr - One of the best experts on this subject based on the ideXlab platform.
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Calcific Tendinitis natural history and association with endocrine disorders
Orthopaedic Proceedings, 2018Co-Authors: Paul Harvie, Pollard Tcb, Andrew CarrAbstract:The purpose of this study was to investigate the association of endocrine disease with Calcific Tendinitis and the effects that such disease has on its natural history.A retrospective observational cohort study of 102 consecutive patients (125 shoulders) with Calcific Tendinitis is presented. Seventy-three (71.6 %) female, 29 (28.4 %) male. Compared with population prevalences, significant levels of endocrine disorders were found in our study cohort. Sixty-six patients (81 shoulders, 62 female (93.9 %), 4 male (6.1 %), mean age 50.3 years) with associated endocrine disease were compared with 36 patients (44 shoulders, 11 female (30.6 %), 25 male (69.4 %), mean age 52.4 years) without endocrine disease. The endocrine cohort were significantly younger than the non-endocrine cohort when symptoms started (mean 40.9 years and 46.9 years respectively, p=0.0026), had significantly longer natural histories (mean 79.7 months compared with 47.1 months, p=0.0015) and a significantly higher proportion underwent opera...
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Calcific Tendinitis natural history and association with endocrine disorders
Journal of Shoulder and Elbow Surgery, 2007Co-Authors: Paul Harvie, T C B Pollard, Andrew CarrAbstract:A retrospective, observational cohort study of 102 consecutive patients (125 shoulders) with Calcific Tendinitis is presented. Of the patients, 73 (71.6%) were women and 29 (28.4%) were men. Compared with population prevalences, significant levels of endocrine disorders were found. We compared 66 patients (62 women [93.9%] and 4 men [6.1%]; mean age, 50.3 years) (81 shoulders) with associated endocrine disease with 36 patients (11 women [30.6%] and 25 men [69.4%]); mean age, 52.4 years) (44 shoulders) without endocrine disease. The endocrine cohort was significantly younger than the non-endocrine cohort when symptoms started (mean, 40.9 years and 46.9 years, respectively), had significantly longer natural histories (mean, 79.7 months compared with 47.1 months), and had a significantly higher proportion who underwent operative treatment (46.9% compared with 22.7%). Disorders of thyroid and estrogen metabolism may contribute to Calcific Tendinitis etiology. Classifying Calcific Tendinitis into type I (idiopathic) and type II (secondary or endocrine-related) aids prognosis and management.
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Calcific Tendinitis natural history and association with endocrine disorders
Journal of Bone and Joint Surgery-british Volume, 2005Co-Authors: Paul Harvie, T C B Pollard, Andrew CarrAbstract:The purpose of this study was to investigate the association of endocrine disease with Calcific Tendinitis and the effects that such disease has on its natural history. A retrospective observational cohort study of 102 consecutive patients (125 shoulders) with Calcific Tendinitis is presented. Seventy-three (71.6 %) female, 29 (28.4 %) male. Compared with population prevalences, significant levels of endocrine disorders were found in our study cohort. Sixty-six patients (81 shoulders, 62 female (93.9 %), 4 male (6.1 %), mean age 50.3 years) with associated endocrine disease were compared with 36 patients (44 shoulders, 11 female (30.6 %), 25 male (69.4 %), mean age 52.4 years) without endocrine disease. The endocrine cohort were significantly younger than the non-endocrine cohort when symptoms started (mean 40.9 years and 46.9 years respectively, p=0.0026), had significantly longer natural histories (mean 79.7 months compared with 47.1 months, p=0.0015) and a significantly higher proportion underwent operative treatment (46.9 % compared with 22.7 %, p=0.0014). Disorders of thyroid and oestrogen metabolism may contribute to Calcific Tendinitis aetiology. Classifying Calcific Tendinitis into Type I idiopathic and Type II secondary or endocrine-related aids prognosis and management.
P Eysel - One of the best experts on this subject based on the ideXlab platform.
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shoulder function after extracorporal shock wave therapy for Calcific Tendinitis
Journal of Shoulder and Elbow Surgery, 1998Co-Authors: J D Rompe, Rainer Burger, C Hopf, P EyselAbstract:Abstract We report a controlled, prospective study that explored the effect of extracorporal shock waves of low- versus high-energy density in patients with chronic shoulder pain and Calcific Tendinitis. We assigned at random 100 patients who had had Calcific Tendinitis for more than 12 months to 2 groups to receive shock wave therapy either of a low- or high-energy density. Group 1 received 1500 impulses of 0.06 mJ/mm2, whereas group 2 received 1500 impulses of 0.28 mJ/mm2. Unlike group 1, in which the shock wave application could be performed without local anesthesia, all patients in group 2 required brachial plexus anesthesia. The patients were reviewed at 6 and 24 weeks. Partial or complete disintegration of the calcareous deposit was observed in 50% of the patients in group 1 and 64% of the patients in group 2 (P
George A. C. Murrell - One of the best experts on this subject based on the ideXlab platform.
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are the symptoms of Calcific Tendinitis due to neoinnervation and or neovascularization
Journal of Bone and Joint Surgery American Volume, 2016Co-Authors: Lisa Hackett, Neal L. Millar, George A. C. MurrellAbstract:Background: Calcific Tendinitis can be a substantial cause of pain and dysfunction in the shoulder, and the pathophysiology is unclear. Recent studies have shown a link among nerve ingrowth, neovascularization, and pain in tendinopathy. The aim of this study was to determine whether there is evidence of neoinnervation and/or neovascularization in Calcific Tendinitis lesions of the shoulder. Methods: At arthroscopy, ultrasound was used to identify calcium within the tendon. Samples were taken from the supraspinatus tendon adjacent to the Calcific lesion (in the Calcific Tendinitis group, with ten patients), the torn supraspinatus tendon of patients undergoing rotator cuff repair (the rotator cuff tear group, with ten patients), and the subscapularis tendon of patients undergoing a stabilization surgical procedure (the control group, with ten patients). Biopsied tendon samples were evaluated immunohistochemically by quantifying the presence of macrophages (using CD68 and CD206), T cells (CD3), mast cells (mast cell tryptase), vascular endothelium (CD34), and peripheral nerve markers (PGP 9.5). Results: There was a twofold to eightfold increase of nerve markers, neovascularization, macrophages, M2 macrophages, and mast cells in the Calcific Tendinitis group compared with the rotator cuff tear group (p < 0.001) and the control group (p < 0.001). Increased nerve counts positively correlated with more frequent extreme pain (r = 0.5, p < 0.01) and with increased neovascularization (r = 0.7, p < 0.01) and counts of CD68 macrophages (r = 0.8, p < 0.01), M2 macrophages (r = 0.6, p < 0.01), and mast cells (r = 0.7, p < 0.01). Conclusions: This is the first study to show a significant increase in neovascularization and neoinnervation in Calcific Tendinitis lesions of the shoulder along with an eightfold increase in mast cells and macrophages. The findings are consistent with the hypothesis that, in Calcific Tendinitis, the Calcific material is inducing a vigorous inflammatory response within the tendon with formation of new blood vessels and nerves. Clinical Relevance: This study helps to explain why Calcific Tendinitis is related to substantial pain in the clinical setting.
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Are the Symptoms of Calcific Tendinitis Due to Neoinnervation and/or Neovascularization?
Journal of Bone and Joint Surgery American Volume, 2016Co-Authors: Lisa Hackett, Neal L. Millar, George A. C. MurrellAbstract:Background: Calcific Tendinitis can be a substantial cause of pain and dysfunction in the shoulder, and the pathophysiology is unclear. Recent studies have shown a link among nerve ingrowth, neovascularization, and pain in tendinopathy. The aim of this study was to determine whether there is evidence of neoinnervation and/or neovascularization in Calcific Tendinitis lesions of the shoulder. Methods: At arthroscopy, ultrasound was used to identify calcium within the tendon. Samples were taken from the supraspinatus tendon adjacent to the Calcific lesion (in the Calcific Tendinitis group, with ten patients), the torn supraspinatus tendon of patients undergoing rotator cuff repair (the rotator cuff tear group, with ten patients), and the subscapularis tendon of patients undergoing a stabilization surgical procedure (the control group, with ten patients). Biopsied tendon samples were evaluated immunohistochemically by quantifying the presence of macrophages (using CD68 and CD206), T cells (CD3), mast cells (mast cell tryptase), vascular endothelium (CD34), and peripheral nerve markers (PGP 9.5). Results: There was a twofold to eightfold increase of nerve markers, neovascularization, macrophages, M2 macrophages, and mast cells in the Calcific Tendinitis group compared with the rotator cuff tear group (p < 0.001) and the control group (p < 0.001). Increased nerve counts positively correlated with more frequent extreme pain (r = 0.5, p < 0.01) and with increased neovascularization (r = 0.7, p < 0.01) and counts of CD68 macrophages (r = 0.8, p < 0.01), M2 macrophages (r = 0.6, p < 0.01), and mast cells (r = 0.7, p < 0.01). Conclusions: This is the first study to show a significant increase in neovascularization and neoinnervation in Calcific Tendinitis lesions of the shoulder along with an eightfold increase in mast cells and macrophages. The findings are consistent with the hypothesis that, in Calcific Tendinitis, the Calcific material is inducing a vigorous inflammatory response within the tendon with formation of new blood vessels and nerves. Clinical Relevance: This study helps to explain why Calcific Tendinitis is related to substantial pain in the clinical setting.