The Experts below are selected from a list of 303 Experts worldwide ranked by ideXlab platform
Anju Chadha - One of the best experts on this subject based on the ideXlab platform.
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regio and enantioselective reduction of diketones preparation of enantiomerically pure hydroxy ketones catalysed by Candida Parapsilosis atcc 7330
Tetrahedron-asymmetry, 2015Co-Authors: Pula Mahajabeen, Anju ChadhaAbstract:Abstract Enantiomerically enriched hydroxy ketones were prepared by the reduction of the corresponding diketones with excellent enantiomeric excess (98%) and in good yields (up to 75%) using whole cells of Candida Parapsilosis ATCC 7330. Cyclic diketones, such as 1,2-cyclohexanedione and 1,4-cyclohexanedione, resulted in hydroxy ketones as products. Cyclohexane-1,3-dione and 5,5-dimethylcyclohexane-1,3-dione gave dimerised products, such as 2,2′-(ethane-1,1-diyl)bis(3-hydroxycyclohex-2-enone) and 2,2′-(ethane-1,1-diyl)bis(3-hydroxy-5,5-dimethylcyclohex-2-enone) with acetaldehyde generated in situ from whole cells of Candida Parapsilosis ATCC 7330, which is reported here for the first time.
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enantioselective oxidation of secondary alcohols by Candida Parapsilosis atcc 7330
RSC Advances, 2014Co-Authors: Thakkellapati Sivakumari, R Preetha, Anju ChadhaAbstract:Optically pure allylic alcohols and 4-phenylbutan-2-ols were prepared by oxidative kinetic resolution using whole cells of Candida Parapsilosis ATCC 7330. Only the ‘S’ enantiomer is selectively oxidized to the corresponding keto compound (yield, 37–46%) leaving the ‘R’ alcohol (yield, 37–52% and ee 46 to >99%). The biocatalytic method is carried out under mild conditions at 20 °C, pH 6.5 in phosphate buffer.
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enantiomerically pure allylic alcohols preparation by Candida Parapsilosis atcc 7330 mediated deracemisation
Tetrahedron-asymmetry, 2008Co-Authors: Devamani Titu, Anju ChadhaAbstract:Biocatalytic deracemisation of racemic allylic alcohols by whole cells of Candida Parapsilosis ATCC 7330 resulted in the formation of the (R)-enantiomers in high enantiomeric excesses (up to >99%) and isolated yields (up to 79%).
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asymmetric reduction of aryl imines using Candida Parapsilosis atcc 7330
Tetrahedron-asymmetry, 2008Co-Authors: Thangavel Vaijayanthi, Anju ChadhaAbstract:Abstract A highly enantioselective one pot, novel biocatalytic method for the asymmetric reduction of aryl imines is reported. Treatment of aryl imines with Candida Parapsilosis ATCC 7330 in aqueous medium produces the enantiomerically pure ( R )-secondary amines in moderate to good yields (55–80%) with excellent enantiomeric excesses (95–>99%).
R Preetha - One of the best experts on this subject based on the ideXlab platform.
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enantioselective oxidation of secondary alcohols by Candida Parapsilosis atcc 7330
RSC Advances, 2014Co-Authors: Thakkellapati Sivakumari, R Preetha, Anju ChadhaAbstract:Optically pure allylic alcohols and 4-phenylbutan-2-ols were prepared by oxidative kinetic resolution using whole cells of Candida Parapsilosis ATCC 7330. Only the ‘S’ enantiomer is selectively oxidized to the corresponding keto compound (yield, 37–46%) leaving the ‘R’ alcohol (yield, 37–52% and ee 46 to >99%). The biocatalytic method is carried out under mild conditions at 20 °C, pH 6.5 in phosphate buffer.
Thakkellapati Sivakumari - One of the best experts on this subject based on the ideXlab platform.
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enantioselective oxidation of secondary alcohols by Candida Parapsilosis atcc 7330
RSC Advances, 2014Co-Authors: Thakkellapati Sivakumari, R Preetha, Anju ChadhaAbstract:Optically pure allylic alcohols and 4-phenylbutan-2-ols were prepared by oxidative kinetic resolution using whole cells of Candida Parapsilosis ATCC 7330. Only the ‘S’ enantiomer is selectively oxidized to the corresponding keto compound (yield, 37–46%) leaving the ‘R’ alcohol (yield, 37–52% and ee 46 to >99%). The biocatalytic method is carried out under mild conditions at 20 °C, pH 6.5 in phosphate buffer.
Thangavel Vaijayanthi - One of the best experts on this subject based on the ideXlab platform.
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asymmetric reduction of aryl imines using Candida Parapsilosis atcc 7330
Tetrahedron-asymmetry, 2008Co-Authors: Thangavel Vaijayanthi, Anju ChadhaAbstract:Abstract A highly enantioselective one pot, novel biocatalytic method for the asymmetric reduction of aryl imines is reported. Treatment of aryl imines with Candida Parapsilosis ATCC 7330 in aqueous medium produces the enantiomerically pure ( R )-secondary amines in moderate to good yields (55–80%) with excellent enantiomeric excesses (95–>99%).
Devamani Titu - One of the best experts on this subject based on the ideXlab platform.
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enantiomerically pure allylic alcohols preparation by Candida Parapsilosis atcc 7330 mediated deracemisation
Tetrahedron-asymmetry, 2008Co-Authors: Devamani Titu, Anju ChadhaAbstract:Biocatalytic deracemisation of racemic allylic alcohols by whole cells of Candida Parapsilosis ATCC 7330 resulted in the formation of the (R)-enantiomers in high enantiomeric excesses (up to >99%) and isolated yields (up to 79%).