The Experts below are selected from a list of 306 Experts worldwide ranked by ideXlab platform
Michael G. Rossmann - One of the best experts on this subject based on the ideXlab platform.
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The Canine Parvovirus Empty Capsid Structure
Journal of molecular biology, 1993Co-Authors: Michael G. RossmannAbstract:Abstract The structure of empty Canine Parvovirus capsids shows that residues 37 to the carboxy-terminal residue 584 (VP2 numbering) are ordered in each of the 60 subunits. The central structural motif of each subunit is the eight-stranded antiparallel β-barrel that has been found in many other virus structures. Five β-hairpin turns form β-cylindrical structure at each icosahedral 5-fold axis. The N-terminal glycine-rich sequence can be accommodated within this cylinder without excessive steric hindrance, consistent with the electron density distribution. By far the largest conformational differences between the full and empty virus were found in the region where some ordered DNA has been observed to bind in Canine Parvovirus full particles. Extensive interactions among 3-fold related subunits indicate that a trimeric subunit might be a viral assembly intermediate.
Zhigang Cao - One of the best experts on this subject based on the ideXlab platform.
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Profiling of Host Cell Response to Successive Canine Parvovirus Infection Based on Kinetic Proteomic Change Identification.
Scientific reports, 2016Co-Authors: Hang Zhao, Yuening Cheng, Jianke Wang, Peng Lin, Yaru Sun, Jingqiang Ren, Mingwei Tong, Zhigang CaoAbstract:Profiling of Host Cell Response to Successive Canine Parvovirus Infection Based on Kinetic Proteomic Change Identification
Hu Yongqiang - One of the best experts on this subject based on the ideXlab platform.
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Rapid detection of Canine Parvovirus by Real-time PCR and PCR methods.
Chinese journal of veterinary science, 2009Co-Authors: Xiong Wei, Li Jian, Gao Lihua, Jiang Jing, Li Chunyang, Huang Zhongrong, Hu YongqiangAbstract:Canine Parvovirus disease caused by Canine Parvovirus(CPV) is one of the most important Canine diseases with widespread infection and high mortality,which is one of the crucial quarantine diseases for entry-exit pets.In order to accelerate inspection efficiency,the methods of PCR and Real-time PCR using TaqMan probe were established.Comparing with PCR method,Real-time PCR assay was proved to be specific with high sensitivity and efficiency.Further,a great quantity of CPV positive samples collected from different sites were detected by Realtime PCR and PCR to evaluate the reliability of these motheds.The results show Real-time PCR and PCR methods have high reliablity and significantly improve the detection efficiency of CPV positive samples.
V. A. Srinivasan - One of the best experts on this subject based on the ideXlab platform.
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Analysis of VP2 gene sequences of Canine Parvovirus isolates in India
Archives of virology, 2006Co-Authors: Shankar R. Chinchkar, B. Mohana Subramanian, N. Hanumantha Rao, Pundi N. Rangarajan, D. Thiagarajan, V. A. SrinivasanAbstract:The epidemiology of Canine Parvovirus (CPV) infections in dogs in India was examined using 27 isolates collected during a two-year period. The VP2 genes of 22 isolates were sequenced, and the deduced amino acid sequences were compared. The results indicated that the isolates belonged to CPV type 2a except four, which belonged to CPV type 2b. Comparison of the VP2 gene sequences revealed that the Indian isolates formed separate lineages distinct from the South East Asian isolates. The Canine Parvovirus isolates in India appear to evolve independently, and distinct geographical patterns of evolution could not be discerned in the isolates examined.
Manli Zhang - One of the best experts on this subject based on the ideXlab platform.
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identification of Canine Parvovirus with the q370r point mutation in the vp2 gene from a giant panda ailuropoda melanoleuca
Virology Journal, 2013Co-Authors: Shaolin Yang, Shijie Chen, Zifang Quan, Chengdong Wang, Zhihe Zhang, Manli ZhangAbstract:Background In this study, we sequenced and phylogenetic analyses of the VP2 genes from twelve Canine Parvovirus (CPV) strains obtained from eleven domestic dogs and a giant panda (Ailuropoda melanoleuca) in China. A novel Canine Parvovirus (CPV) was detected from the giant panda in China.
