The Experts below are selected from a list of 16113 Experts worldwide ranked by ideXlab platform
Jessica K. Gordon - One of the best experts on this subject based on the ideXlab platform.
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Integration of Capillary Microscopy and dermoscopy into the rheumatology fellow curriculum.
Clinical and experimental rheumatology, 2017Co-Authors: Christopher Hatzis, Vanessa Smith, Daniele Lerner, Stephen A. Paget, Maurizio Cutolo, Robert Spiera, Jessica K. GordonAbstract:OBJECTIVES This study evaluates a novel, three-part nailfold capillaroscopy training curriculum for adult and paediatric rheumatology fellows. METHODS All rheumatology fellows training at an academic medical centre took part in the three-part nailfold capillaroscopy curriculum. Tests of fellows' usage, interest, confidence, and ability in nailfold capillaroscopy were taken at multiple time-points throughout the curriculum. RESULTS Fellows self-reported high levels of interest, increased confidence in delineating normal and abnormal nailfold capillaries (p=0.03) and increased usage of nailfold capillaroscopy (p=0.09). The ability of fellows to identify normal nailfold capillaries (p=0.03) and systemic sclerosis-specific nailfold Capillary changes, such as neoangiogenesis (p
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integration of Capillary Microscopy and dermoscopy into the rheumatology fellow curriculum
Clinical and Experimental Rheumatology, 2017Co-Authors: Christopher Hatzis, Vanessa Smith, Daniele Lerner, Stephen A. Paget, Maurizio Cutolo, Robert Spiera, Jessica K. GordonAbstract:OBJECTIVES This study evaluates a novel, three-part nailfold capillaroscopy training curriculum for adult and paediatric rheumatology fellows. METHODS All rheumatology fellows training at an academic medical centre took part in the three-part nailfold capillaroscopy curriculum. Tests of fellows' usage, interest, confidence, and ability in nailfold capillaroscopy were taken at multiple time-points throughout the curriculum. RESULTS Fellows self-reported high levels of interest, increased confidence in delineating normal and abnormal nailfold capillaries (p=0.03) and increased usage of nailfold capillaroscopy (p=0.09). The ability of fellows to identify normal nailfold capillaries (p=0.03) and systemic sclerosis-specific nailfold Capillary changes, such as neoangiogenesis (p<0.001), also increased. CONCLUSIONS The curriculum was feasible and led to improved ability of learners to distinguish normal from abnormal and to recognise and describe systemic sclerosis-specific nailfold Capillary changes. This curriculum also led to improved confidence in examining nailfold capillaries and increased usage of this skill in rheumatologic consultation.
Jenny Gun - One of the best experts on this subject based on the ideXlab platform.
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scanning Capillary Microscopy mass spectrometry for mapping spatial electrochemical activity of electrodes
Analytical Chemistry, 2001Co-Authors: Alexander D. Modestov, Simcha Srebnik, Ovadia Lev, Jenny GunAbstract:A new technique for microscopic imaging of electrochemically active surfaces is introduced. The technique combines concepts of probe Microscopy and advances in mass spectrometry. The technique is based on a miniature electrochemical flow cell scanner. A liquid feed stream containing a redox component is introduced to the vicinity of the examined location through the annulus of a coaxial Capillary set. The incoming reagent interacts with the target location, and the generated product stream is transferred through the inner Capillary to an electrospray mass spectrometer, ESI-MS. Thus, a multicomponent, potential-dependent image of the products' distribution versus the location on the electrode is generated. The use of the technique is demonstrated by scanning the electrochemical heterogeneity of model electrodes.
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Scanning Capillary Microscopy/Mass Spectrometry for Mapping Spatial Electrochemical Activity of Electrodes
Analytical Chemistry, 2001Co-Authors: Alexander D. Modestov, Simcha Srebnik, Ovadia Lev, Jenny GunAbstract:A new technique for microscopic imaging of electrochemically active surfaces is introduced. The technique combines concepts of probe Microscopy and advances in mass spectrometry. The technique is based on a miniature electrochemical flow cell scanner. A liquid feed stream containing a redox component is introduced to the vicinity of the examined location through the annulus of a coaxial Capillary set. The incoming reagent interacts with the target location, and the generated product stream is transferred through the inner Capillary to an electrospray mass spectrometer, ESI-MS. Thus, a multicomponent, potential-dependent image of the products' distribution versus the location on the electrode is generated. The use of the technique is demonstrated by scanning the electrochemical heterogeneity of model electrodes.
Christopher Hatzis - One of the best experts on this subject based on the ideXlab platform.
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Integration of Capillary Microscopy and dermoscopy into the rheumatology fellow curriculum.
Clinical and experimental rheumatology, 2017Co-Authors: Christopher Hatzis, Vanessa Smith, Daniele Lerner, Stephen A. Paget, Maurizio Cutolo, Robert Spiera, Jessica K. GordonAbstract:OBJECTIVES This study evaluates a novel, three-part nailfold capillaroscopy training curriculum for adult and paediatric rheumatology fellows. METHODS All rheumatology fellows training at an academic medical centre took part in the three-part nailfold capillaroscopy curriculum. Tests of fellows' usage, interest, confidence, and ability in nailfold capillaroscopy were taken at multiple time-points throughout the curriculum. RESULTS Fellows self-reported high levels of interest, increased confidence in delineating normal and abnormal nailfold capillaries (p=0.03) and increased usage of nailfold capillaroscopy (p=0.09). The ability of fellows to identify normal nailfold capillaries (p=0.03) and systemic sclerosis-specific nailfold Capillary changes, such as neoangiogenesis (p
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integration of Capillary Microscopy and dermoscopy into the rheumatology fellow curriculum
Clinical and Experimental Rheumatology, 2017Co-Authors: Christopher Hatzis, Vanessa Smith, Daniele Lerner, Stephen A. Paget, Maurizio Cutolo, Robert Spiera, Jessica K. GordonAbstract:OBJECTIVES This study evaluates a novel, three-part nailfold capillaroscopy training curriculum for adult and paediatric rheumatology fellows. METHODS All rheumatology fellows training at an academic medical centre took part in the three-part nailfold capillaroscopy curriculum. Tests of fellows' usage, interest, confidence, and ability in nailfold capillaroscopy were taken at multiple time-points throughout the curriculum. RESULTS Fellows self-reported high levels of interest, increased confidence in delineating normal and abnormal nailfold capillaries (p=0.03) and increased usage of nailfold capillaroscopy (p=0.09). The ability of fellows to identify normal nailfold capillaries (p=0.03) and systemic sclerosis-specific nailfold Capillary changes, such as neoangiogenesis (p<0.001), also increased. CONCLUSIONS The curriculum was feasible and led to improved ability of learners to distinguish normal from abnormal and to recognise and describe systemic sclerosis-specific nailfold Capillary changes. This curriculum also led to improved confidence in examining nailfold capillaries and increased usage of this skill in rheumatologic consultation.
Michael E. Gschwandtner - One of the best experts on this subject based on the ideXlab platform.
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microcirculation in mixed arterial venous ulcers and the surrounding skin clinical study using a laser doppler perfusion imager and Capillary Microscopy
Wound Repair and Regeneration, 2009Co-Authors: Ewald Ambrozy, Herbert Ehringer, Renate Koppensteiner, Iveta Waczulíková, Andrea Willfortehringer, Michael E. GschwandtnerAbstract:To treat mixed skin ulcers effectively, it is important to investigate skin microcirculation in greater detail. Therefore, we used laser Doppler perfusion imaging and Capillary Microscopy for assessing both subpapillary and nutritive microcirculation in four defined regions of the skin in 17 patients with mixed ulcers caused by a combination of peripheral arterial occlusive disease and chronic venous insufficiency. Laser Doppler area flux was significantly higher in the ulcer areas than in the areas without granulation tissue and those in intact skin. The flux in the scars was higher than that in the intact skin or in the ulcer areas without granulation tissue. Capillary density in the intact skin was higher than the densities in nongranulation tissue areas, granulation areas, and scar areas (p<0.001 for all comparisons). To conclude, the ulcer areas without granulation tissue did not show a healing tendency due to poor subpapillary and nutritive perfusion; the granulation tissue exhibited high subpapillary perfusion as a sign of healing. In the scars, sufficient blood supply could be detected in both layers as a sign of an almost complete healing process. Blood supply in the intact skin is, however, already affected by distorted microcirculation in the ulcers.
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Microcirculation in mixed arterial/venous ulcers and the surrounding skin: clinical study using a laser Doppler perfusion imager and Capillary Microscopy.
Wound Repair and Regeneration, 2009Co-Authors: Ewald Ambrozy, Herbert Ehringer, Renate Koppensteiner, Iveta Waczulíková, Andrea Willfort-ehringer, Michael E. GschwandtnerAbstract:To treat mixed skin ulcers effectively, it is important to investigate skin microcirculation in greater detail. Therefore, we used laser Doppler perfusion imaging and Capillary Microscopy for assessing both subpapillary and nutritive microcirculation in four defined regions of the skin in 17 patients with mixed ulcers caused by a combination of peripheral arterial occlusive disease and chronic venous insufficiency. Laser Doppler area flux was significantly higher in the ulcer areas than in the areas without granulation tissue and those in intact skin. The flux in the scars was higher than that in the intact skin or in the ulcer areas without granulation tissue. Capillary density in the intact skin was higher than the densities in nongranulation tissue areas, granulation areas, and scar areas (p
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Laser Doppler imaging and Capillary Microscopy in ischemic ulcers.
Atherosclerosis, 1999Co-Authors: Michael E. Gschwandtner, Ewald Ambrozy, Barbara Schneider, Sonja Fasching, Andrea Willfort, Herbert EhringerAbstract:Abstract The local distribution of laser Doppler flux (mainly thermoregulatory perfusion) and Capillary density (nutritive circulation) within 25 ischemic leg ulcers and their adjacent skin were investigated. For this purpose the technique of laser Doppler imaging and Capillary Microscopy were applied. In each ulcer a non granulation tissue area (NGTA), a granulation tissue area (GTA) and in adjacent skin a skin area (SA) were defined. In these areas the average laser Doppler area flux (arbitrary units, AU) and the number of capillaries/mm 2 were determined for each patient. The mean±S.D. of laser Doppler area fluxes were: NGTA 1.30±1.93, GTA 2.13±1.53 and SA 1.21±0.77 AU, respectively. The differences between GTA and NGTA or SA was statistically significant ( p 2 , respectively. The following differences were statistically significant: NGTA versus GTA ( p p
Alexander D. Modestov - One of the best experts on this subject based on the ideXlab platform.
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scanning Capillary Microscopy mass spectrometry for mapping spatial electrochemical activity of electrodes
Analytical Chemistry, 2001Co-Authors: Alexander D. Modestov, Simcha Srebnik, Ovadia Lev, Jenny GunAbstract:A new technique for microscopic imaging of electrochemically active surfaces is introduced. The technique combines concepts of probe Microscopy and advances in mass spectrometry. The technique is based on a miniature electrochemical flow cell scanner. A liquid feed stream containing a redox component is introduced to the vicinity of the examined location through the annulus of a coaxial Capillary set. The incoming reagent interacts with the target location, and the generated product stream is transferred through the inner Capillary to an electrospray mass spectrometer, ESI-MS. Thus, a multicomponent, potential-dependent image of the products' distribution versus the location on the electrode is generated. The use of the technique is demonstrated by scanning the electrochemical heterogeneity of model electrodes.
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Scanning Capillary Microscopy/Mass Spectrometry for Mapping Spatial Electrochemical Activity of Electrodes
Analytical Chemistry, 2001Co-Authors: Alexander D. Modestov, Simcha Srebnik, Ovadia Lev, Jenny GunAbstract:A new technique for microscopic imaging of electrochemically active surfaces is introduced. The technique combines concepts of probe Microscopy and advances in mass spectrometry. The technique is based on a miniature electrochemical flow cell scanner. A liquid feed stream containing a redox component is introduced to the vicinity of the examined location through the annulus of a coaxial Capillary set. The incoming reagent interacts with the target location, and the generated product stream is transferred through the inner Capillary to an electrospray mass spectrometer, ESI-MS. Thus, a multicomponent, potential-dependent image of the products' distribution versus the location on the electrode is generated. The use of the technique is demonstrated by scanning the electrochemical heterogeneity of model electrodes.
