The Experts below are selected from a list of 2583 Experts worldwide ranked by ideXlab platform
H. Sekino - One of the best experts on this subject based on the ideXlab platform.
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Melanotropin-potentiating factor isolated from filtrate of uremic patients suffering from melanosis and Carbohydrate Intolerance
Amino Acids, 1995Co-Authors: T. Abiko, H. SekinoAbstract:Following the characterization of a hexadecapeptide, α -endorphin, melanotropin-potentiating factor (MPF) was isolated from the filtrate of uremic patients suffering from melanosis and Carbohydrate Intolerance. The structure of MPF has been determined on the bases of chemical and physicochemical examinations which included HPLC, Edman sequence analysis combined analysis of the amino acid composition and FAB-MS analysis. An accumulation of MPF might be a cause of melanosis in uremic patients.
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Isα-endorphin an uremic toxin?α-Endorphin isolated from filtrate of uremic patients with Carbohydrate Intolerance
Amino Acids, 1993Co-Authors: T. Abiko, H. SekinoAbstract:A 16-residue peptide was isolated from filtrate of uremic patients with Carbohydrate Intolerance by ultrafiltration with an Amicon Centriflo DM-5 membrane, followed by gel-filtration on Sephadex G-50 and Sephadex G-25, droplet countercurrent chromatography and high performance liquid chromatography. The hexadecapeptide thus obtained was identical as the entire amino acid sequence of α -endorphin by amino acid analysis, application of the Edman degradation analysis and measurement of physical constants and analytical data of the synthetic hexadecapeptide. This result seems to suggest that an accumulation of α -endorphin in uremic patients might cause Carbohydrate Intolerance.
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isα endorphin an uremic toxin α endorphin isolated from filtrate of uremic patients with Carbohydrate Intolerance
Amino Acids, 1993Co-Authors: T. Abiko, H. SekinoAbstract:A 16-residue peptide was isolated from filtrate of uremic patients with Carbohydrate Intolerance by ultrafiltration with an Amicon Centriflo DM-5 membrane, followed by gel-filtration on Sephadex G-50 and Sephadex G-25, droplet countercurrent chromatography and high performance liquid chromatography. The hexadecapeptide thus obtained was identical as the entire amino acid sequence ofα-endorphin by amino acid analysis, application of the Edman degradation analysis and measurement of physical constants and analytical data of the synthetic hexadecapeptide. This result seems to suggest that an accumulation ofα-endorphin in uremic patients might cause Carbohydrate Intolerance.
T. Abiko - One of the best experts on this subject based on the ideXlab platform.
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Melanotropin-potentiating factor isolated from filtrate of uremic patients suffering from melanosis and Carbohydrate Intolerance
Amino Acids, 1995Co-Authors: T. Abiko, H. SekinoAbstract:Following the characterization of a hexadecapeptide, α -endorphin, melanotropin-potentiating factor (MPF) was isolated from the filtrate of uremic patients suffering from melanosis and Carbohydrate Intolerance. The structure of MPF has been determined on the bases of chemical and physicochemical examinations which included HPLC, Edman sequence analysis combined analysis of the amino acid composition and FAB-MS analysis. An accumulation of MPF might be a cause of melanosis in uremic patients.
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Isα-endorphin an uremic toxin?α-Endorphin isolated from filtrate of uremic patients with Carbohydrate Intolerance
Amino Acids, 1993Co-Authors: T. Abiko, H. SekinoAbstract:A 16-residue peptide was isolated from filtrate of uremic patients with Carbohydrate Intolerance by ultrafiltration with an Amicon Centriflo DM-5 membrane, followed by gel-filtration on Sephadex G-50 and Sephadex G-25, droplet countercurrent chromatography and high performance liquid chromatography. The hexadecapeptide thus obtained was identical as the entire amino acid sequence of α -endorphin by amino acid analysis, application of the Edman degradation analysis and measurement of physical constants and analytical data of the synthetic hexadecapeptide. This result seems to suggest that an accumulation of α -endorphin in uremic patients might cause Carbohydrate Intolerance.
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isα endorphin an uremic toxin α endorphin isolated from filtrate of uremic patients with Carbohydrate Intolerance
Amino Acids, 1993Co-Authors: T. Abiko, H. SekinoAbstract:A 16-residue peptide was isolated from filtrate of uremic patients with Carbohydrate Intolerance by ultrafiltration with an Amicon Centriflo DM-5 membrane, followed by gel-filtration on Sephadex G-50 and Sephadex G-25, droplet countercurrent chromatography and high performance liquid chromatography. The hexadecapeptide thus obtained was identical as the entire amino acid sequence ofα-endorphin by amino acid analysis, application of the Edman degradation analysis and measurement of physical constants and analytical data of the synthetic hexadecapeptide. This result seems to suggest that an accumulation ofα-endorphin in uremic patients might cause Carbohydrate Intolerance.
B Bonin - One of the best experts on this subject based on the ideXlab platform.
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Assessment of factors related to Carbohydrate Intolerance II: OGTT glucose at 120 minutes (LB298)
The FASEB Journal, 2014Co-Authors: Elfego Galvan, K Levers, A Coletta, Ryan Dalton, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The OGTT is a gold standard in assessing Carbohydrate Intolerance (CI) and insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a carbohydrat...
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Assessment of factors related to Carbohydrate Intolerance III: Fasting HOMA (LB300)
The FASEB Journal, 2014Co-Authors: Ryan Dalton, K Levers, Elfego Galvan, A Coletta, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The fasting homeostatic model assessment (HOMA) is a gold standard in assessing insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a Carbohydrate Intolerance survey (CI) correlate to HOMA, an OGTT, body composition and/or markers of health. 108 women (31.6±13 yrs, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75g, 2-hr OGTT. Pearson product correlations were performed to determine which factors correlated with HOMA. Results revealed significant correlations (p
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Assessment of factors related to Carbohydrate Intolerance I: OGTT glucose AUC (LB299)
The FASEB Journal, 2014Co-Authors: K Levers, Elfego Galvan, A Coletta, Ryan Dalton, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The OGTT is a gold standard in assessing Carbohydrate Intolerance (CI) and insulin resistance. However, the test is costly and time consuming. This study examined whether a CI survey could predict response to an OGTT. 108 women (31.6±13 yr, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75 g OGTT in which glucose samples and perceptions of CI symptoms were obtained at 0, 30, 60, 90, and 120 minutes. Pearson product correlations were performed to determine which factors correlated with OGTT glucose AUC. Results revealed significant correlations (p
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assessment of factors related to Carbohydrate Intolerance iii fasting homa lb300
The FASEB Journal, 2014Co-Authors: Ryan Dalton, K Levers, Elfego Galvan, A Coletta, Y Jung, C Goodenough, Sunday Simbo, C Seesselberg, A Oconnor, B BoninAbstract:The fasting homeostatic model assessment (HOMA) is a gold standard in assessing insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a Carbohydrate Intolerance survey (CI) correlate to HOMA, an OGTT, body composition and/or markers of health. 108 women (31.6±13 yrs, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75g, 2-hr OGTT. Pearson product correlations were performed to determine which factors correlated with HOMA. Results revealed significant correlations (p<0.05) in HOMA (1.51±1.1) to G120 (r=0.37), glucose AUC (r=0.30), glucose AUMC (r=0.32), Cmax (r=0.24), fasting insulin (r=0.99), G/I ratio (r=-0.49), height (r=-0.27), waist circumference (r=0.26), BMI (r=0.21), BMC (r=-0.21), BMD (r=-0.27), DEXA body fat (r=0.28), and BIA body fat (r=0.23). However, HOMA did not significantly correlate to any question on the CI or symptoms during t...
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assessment of factors related to Carbohydrate Intolerance i ogtt glucose auc lb299
The FASEB Journal, 2014Co-Authors: K Levers, Elfego Galvan, A Coletta, Y Jung, C Goodenough, C Seesselberg, A Oconnor, R Dalton, S Simbo, B BoninAbstract:The OGTT is a gold standard in assessing Carbohydrate Intolerance (CI) and insulin resistance. However, the test is costly and time consuming. This study examined whether a CI survey could predict response to an OGTT. 108 women (31.6±13 yr, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75 g OGTT in which glucose samples and perceptions of CI symptoms were obtained at 0, 30, 60, 90, and 120 minutes. Pearson product correlations were performed to determine which factors correlated with OGTT glucose AUC. Results revealed significant correlations (p<0.05) in GAUC (264±46 mg/hr/dL) to G120 AUC (r=0.43), glucose AUMC (r=0.97), Cmax (r=0.91), fasting insulin (r=0.26), HOMA (r=0.30), height (r=-0.28), resting HR (r=0.19), BMC (r=-0.36), BMD (r=-0.32), FFM (r=-0.28), being overweight since very young (r=0.27), and slowly gaining weight after age 30. These findings indicate that OGTT GAUC is positively co...
C Seesselberg - One of the best experts on this subject based on the ideXlab platform.
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Analysis of the validity of a Carbohydrate Intolerance questionnaire III (LB303)
The FASEB Journal, 2014Co-Authors: Majid Koozehchian, K Levers, Elfego Galvan, A Coletta, Ryan Dalton, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C SeesselbergAbstract:The purpose of this study was to examine the relationship of responses to a Carbohydrate Intolerance (CI) questionnaire to body composition and markers of health. 108 women (31.6±13 yrs, 34.7±7% bo...
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Assessment of factors related to Carbohydrate Intolerance II: OGTT glucose at 120 minutes (LB298)
The FASEB Journal, 2014Co-Authors: Elfego Galvan, K Levers, A Coletta, Ryan Dalton, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The OGTT is a gold standard in assessing Carbohydrate Intolerance (CI) and insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a carbohydrat...
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Assessment of factors related to Carbohydrate Intolerance III: Fasting HOMA (LB300)
The FASEB Journal, 2014Co-Authors: Ryan Dalton, K Levers, Elfego Galvan, A Coletta, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The fasting homeostatic model assessment (HOMA) is a gold standard in assessing insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a Carbohydrate Intolerance survey (CI) correlate to HOMA, an OGTT, body composition and/or markers of health. 108 women (31.6±13 yrs, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75g, 2-hr OGTT. Pearson product correlations were performed to determine which factors correlated with HOMA. Results revealed significant correlations (p
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Assessment of factors related to Carbohydrate Intolerance I: OGTT glucose AUC (LB299)
The FASEB Journal, 2014Co-Authors: K Levers, Elfego Galvan, A Coletta, Ryan Dalton, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The OGTT is a gold standard in assessing Carbohydrate Intolerance (CI) and insulin resistance. However, the test is costly and time consuming. This study examined whether a CI survey could predict response to an OGTT. 108 women (31.6±13 yr, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75 g OGTT in which glucose samples and perceptions of CI symptoms were obtained at 0, 30, 60, 90, and 120 minutes. Pearson product correlations were performed to determine which factors correlated with OGTT glucose AUC. Results revealed significant correlations (p
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assessment of factors related to Carbohydrate Intolerance iii fasting homa lb300
The FASEB Journal, 2014Co-Authors: Ryan Dalton, K Levers, Elfego Galvan, A Coletta, Y Jung, C Goodenough, Sunday Simbo, C Seesselberg, A Oconnor, B BoninAbstract:The fasting homeostatic model assessment (HOMA) is a gold standard in assessing insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a Carbohydrate Intolerance survey (CI) correlate to HOMA, an OGTT, body composition and/or markers of health. 108 women (31.6±13 yrs, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75g, 2-hr OGTT. Pearson product correlations were performed to determine which factors correlated with HOMA. Results revealed significant correlations (p<0.05) in HOMA (1.51±1.1) to G120 (r=0.37), glucose AUC (r=0.30), glucose AUMC (r=0.32), Cmax (r=0.24), fasting insulin (r=0.99), G/I ratio (r=-0.49), height (r=-0.27), waist circumference (r=0.26), BMI (r=0.21), BMC (r=-0.21), BMD (r=-0.27), DEXA body fat (r=0.28), and BIA body fat (r=0.23). However, HOMA did not significantly correlate to any question on the CI or symptoms during t...
Elfego Galvan - One of the best experts on this subject based on the ideXlab platform.
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Analysis of the validity of a Carbohydrate Intolerance questionnaire III (LB303)
The FASEB Journal, 2014Co-Authors: Majid Koozehchian, K Levers, Elfego Galvan, A Coletta, Ryan Dalton, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C SeesselbergAbstract:The purpose of this study was to examine the relationship of responses to a Carbohydrate Intolerance (CI) questionnaire to body composition and markers of health. 108 women (31.6±13 yrs, 34.7±7% bo...
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Assessment of factors related to Carbohydrate Intolerance II: OGTT glucose at 120 minutes (LB298)
The FASEB Journal, 2014Co-Authors: Elfego Galvan, K Levers, A Coletta, Ryan Dalton, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The OGTT is a gold standard in assessing Carbohydrate Intolerance (CI) and insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a carbohydrat...
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Assessment of factors related to Carbohydrate Intolerance III: Fasting HOMA (LB300)
The FASEB Journal, 2014Co-Authors: Ryan Dalton, K Levers, Elfego Galvan, A Coletta, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The fasting homeostatic model assessment (HOMA) is a gold standard in assessing insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a Carbohydrate Intolerance survey (CI) correlate to HOMA, an OGTT, body composition and/or markers of health. 108 women (31.6±13 yrs, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75g, 2-hr OGTT. Pearson product correlations were performed to determine which factors correlated with HOMA. Results revealed significant correlations (p
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Assessment of factors related to Carbohydrate Intolerance I: OGTT glucose AUC (LB299)
The FASEB Journal, 2014Co-Authors: K Levers, Elfego Galvan, A Coletta, Ryan Dalton, Y Jung, A O'connor, C Goodenough, Sunday Simbo, C Seesselberg, B BoninAbstract:The OGTT is a gold standard in assessing Carbohydrate Intolerance (CI) and insulin resistance. However, the test is costly and time consuming. This study examined whether a CI survey could predict response to an OGTT. 108 women (31.6±13 yr, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75 g OGTT in which glucose samples and perceptions of CI symptoms were obtained at 0, 30, 60, 90, and 120 minutes. Pearson product correlations were performed to determine which factors correlated with OGTT glucose AUC. Results revealed significant correlations (p
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assessment of factors related to Carbohydrate Intolerance iii fasting homa lb300
The FASEB Journal, 2014Co-Authors: Ryan Dalton, K Levers, Elfego Galvan, A Coletta, Y Jung, C Goodenough, Sunday Simbo, C Seesselberg, A Oconnor, B BoninAbstract:The fasting homeostatic model assessment (HOMA) is a gold standard in assessing insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a Carbohydrate Intolerance survey (CI) correlate to HOMA, an OGTT, body composition and/or markers of health. 108 women (31.6±13 yrs, 34.7±7% body fat, 25.3±4 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75g, 2-hr OGTT. Pearson product correlations were performed to determine which factors correlated with HOMA. Results revealed significant correlations (p<0.05) in HOMA (1.51±1.1) to G120 (r=0.37), glucose AUC (r=0.30), glucose AUMC (r=0.32), Cmax (r=0.24), fasting insulin (r=0.99), G/I ratio (r=-0.49), height (r=-0.27), waist circumference (r=0.26), BMI (r=0.21), BMC (r=-0.21), BMD (r=-0.27), DEXA body fat (r=0.28), and BIA body fat (r=0.23). However, HOMA did not significantly correlate to any question on the CI or symptoms during t...