The Experts below are selected from a list of 864 Experts worldwide ranked by ideXlab platform
Hemminki K. - One of the best experts on this subject based on the ideXlab platform.
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Research recommendations for selected IARC-classified agents. Review
2010Co-Authors: Ward E.m., Schulte P.a., Straif K., Hopf N.b., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances for which evidence of Carcinogenicity is substantial but not yet conclusive for humans. Our objectives were to identify research gaps and needs for 20 agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: For each chemical agent (or category of agents), a systematic review was conducted of new data published since the most recent pertinent International Agency for Research on Cancer (IARC) Monograph meeting on that agent. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress, and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes
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Research recommendations for selected IARC-classified agents
'Environmental Health Perspectives', 2010Co-Authors: Ward E.m., Hopf, Nancy B, Schulte P.a., Straif K., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances where evidence of Carcinogenicity is substantial but not yet conclusive for humans. The objectives are to identify research gaps and needs for twenty agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: A systematic review was conducted of new data published since the most recent pertinent IARC monograph meeting. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes.[Authors]]]> Animals; Carcinogenicity Tests; Evidence-Based Medicine; Humans eng https://serval.unil.ch/resource/serval:BIB_6F098A7FF9B0.P002/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/openAccess CC0 1.0 https://creativecommons.org/publicdomain/zero/1.0/ application/pdf oai:serval.unil.ch:BIB_6EFF1A8DA7BB 2022-01-08T02:20:29Z openaire documents https://serval.unil.ch/notice/serval:BIB_6EFF1A8DA7BB Mental health and its associations with weight in women with gestational diabetes mellitus. A prospective clinical cohort study. info:doi:10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/pmid/33895430 Gilbert, L. Rossel, J.B. Quansah, D.Y. Puder, J.J. Horsch, A. info:eu-repo/semantics/article article 2021-07 Journal of psychosomatic research, vol. 146, pp. 110489 info:eu-repo/semantics/altIdentifier/eissn/1879-1360 urn:issn:0022-3999
Ward E.m. - One of the best experts on this subject based on the ideXlab platform.
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Research recommendations for selected IARC-classified agents. Review
2010Co-Authors: Ward E.m., Schulte P.a., Straif K., Hopf N.b., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances for which evidence of Carcinogenicity is substantial but not yet conclusive for humans. Our objectives were to identify research gaps and needs for 20 agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: For each chemical agent (or category of agents), a systematic review was conducted of new data published since the most recent pertinent International Agency for Research on Cancer (IARC) Monograph meeting on that agent. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress, and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes
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Research recommendations for selected IARC-classified agents
'Environmental Health Perspectives', 2010Co-Authors: Ward E.m., Hopf, Nancy B, Schulte P.a., Straif K., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances where evidence of Carcinogenicity is substantial but not yet conclusive for humans. The objectives are to identify research gaps and needs for twenty agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: A systematic review was conducted of new data published since the most recent pertinent IARC monograph meeting. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes.[Authors]]]> Animals; Carcinogenicity Tests; Evidence-Based Medicine; Humans eng https://serval.unil.ch/resource/serval:BIB_6F098A7FF9B0.P002/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/openAccess CC0 1.0 https://creativecommons.org/publicdomain/zero/1.0/ application/pdf oai:serval.unil.ch:BIB_6EFF1A8DA7BB 2022-01-08T02:20:29Z openaire documents https://serval.unil.ch/notice/serval:BIB_6EFF1A8DA7BB Mental health and its associations with weight in women with gestational diabetes mellitus. A prospective clinical cohort study. info:doi:10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/pmid/33895430 Gilbert, L. Rossel, J.B. Quansah, D.Y. Puder, J.J. Horsch, A. info:eu-repo/semantics/article article 2021-07 Journal of psychosomatic research, vol. 146, pp. 110489 info:eu-repo/semantics/altIdentifier/eissn/1879-1360 urn:issn:0022-3999
Hopf, Nancy B - One of the best experts on this subject based on the ideXlab platform.
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Research recommendations for selected IARC-classified agents.
eScholarship University of California, 2010Co-Authors: Ward, Elizabeth M, Schulte, Paul A, Straif Kurt, Hopf, Nancy B, Caldwell, Jane C, Carreón Tania, Demarini, David M, Fowler, Bruce A, Goldstein, Bernard D, Hemminki KariAbstract:ObjectivesThere are some common occupational agents and exposure circumstances for which evidence of Carcinogenicity is substantial but not yet conclusive for humans. Our objectives were to identify research gaps and needs for 20 agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans.Data sourcesFor each chemical agent (or category of agents), a systematic review was conducted of new data published since the most recent pertinent International Agency for Research on Cancer (IARC) Monograph meeting on that agent.Data extractionReviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches.Data synthesisSeveral overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress, and immuno- and hormonal modulation.ConclusionsStudies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes
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Research recommendations for selected IARC-classified agents
'Environmental Health Perspectives', 2010Co-Authors: Ward E.m., Hopf, Nancy B, Schulte P.a., Straif K., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances where evidence of Carcinogenicity is substantial but not yet conclusive for humans. The objectives are to identify research gaps and needs for twenty agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: A systematic review was conducted of new data published since the most recent pertinent IARC monograph meeting. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes.[Authors]]]> Animals; Carcinogenicity Tests; Evidence-Based Medicine; Humans eng https://serval.unil.ch/resource/serval:BIB_6F098A7FF9B0.P002/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/openAccess CC0 1.0 https://creativecommons.org/publicdomain/zero/1.0/ application/pdf oai:serval.unil.ch:BIB_6EFF1A8DA7BB 2022-01-08T02:20:29Z openaire documents https://serval.unil.ch/notice/serval:BIB_6EFF1A8DA7BB Mental health and its associations with weight in women with gestational diabetes mellitus. A prospective clinical cohort study. info:doi:10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/pmid/33895430 Gilbert, L. Rossel, J.B. Quansah, D.Y. Puder, J.J. Horsch, A. info:eu-repo/semantics/article article 2021-07 Journal of psychosomatic research, vol. 146, pp. 110489 info:eu-repo/semantics/altIdentifier/eissn/1879-1360 urn:issn:0022-3999
Schulte P.a. - One of the best experts on this subject based on the ideXlab platform.
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Research recommendations for selected IARC-classified agents. Review
2010Co-Authors: Ward E.m., Schulte P.a., Straif K., Hopf N.b., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances for which evidence of Carcinogenicity is substantial but not yet conclusive for humans. Our objectives were to identify research gaps and needs for 20 agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: For each chemical agent (or category of agents), a systematic review was conducted of new data published since the most recent pertinent International Agency for Research on Cancer (IARC) Monograph meeting on that agent. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress, and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes
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Research recommendations for selected IARC-classified agents
'Environmental Health Perspectives', 2010Co-Authors: Ward E.m., Hopf, Nancy B, Schulte P.a., Straif K., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances where evidence of Carcinogenicity is substantial but not yet conclusive for humans. The objectives are to identify research gaps and needs for twenty agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: A systematic review was conducted of new data published since the most recent pertinent IARC monograph meeting. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes.[Authors]]]> Animals; Carcinogenicity Tests; Evidence-Based Medicine; Humans eng https://serval.unil.ch/resource/serval:BIB_6F098A7FF9B0.P002/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/openAccess CC0 1.0 https://creativecommons.org/publicdomain/zero/1.0/ application/pdf oai:serval.unil.ch:BIB_6EFF1A8DA7BB 2022-01-08T02:20:29Z openaire documents https://serval.unil.ch/notice/serval:BIB_6EFF1A8DA7BB Mental health and its associations with weight in women with gestational diabetes mellitus. A prospective clinical cohort study. info:doi:10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/pmid/33895430 Gilbert, L. Rossel, J.B. Quansah, D.Y. Puder, J.J. Horsch, A. info:eu-repo/semantics/article article 2021-07 Journal of psychosomatic research, vol. 146, pp. 110489 info:eu-repo/semantics/altIdentifier/eissn/1879-1360 urn:issn:0022-3999
Straif K. - One of the best experts on this subject based on the ideXlab platform.
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Research recommendations for selected IARC-classified agents. Review
2010Co-Authors: Ward E.m., Schulte P.a., Straif K., Hopf N.b., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances for which evidence of Carcinogenicity is substantial but not yet conclusive for humans. Our objectives were to identify research gaps and needs for 20 agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: For each chemical agent (or category of agents), a systematic review was conducted of new data published since the most recent pertinent International Agency for Research on Cancer (IARC) Monograph meeting on that agent. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress, and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes
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Research recommendations for selected IARC-classified agents
'Environmental Health Perspectives', 2010Co-Authors: Ward E.m., Hopf, Nancy B, Schulte P.a., Straif K., Caldwell J.c., Carreon T., Demarini D.m., Fowler B.a., Goldstein B.d., Hemminki K.Abstract:OBJECTIVES: There are some common occupational agents and exposure circumstances where evidence of Carcinogenicity is substantial but not yet conclusive for humans. The objectives are to identify research gaps and needs for twenty agents prioritized for review based on evidence of widespread human exposures and potential Carcinogenicity in animals or humans. DATA SOURCES: A systematic review was conducted of new data published since the most recent pertinent IARC monograph meeting. DATA EXTRACTION: Reviewers were charged with identifying data gaps and general and specific approaches to address them, focusing on research that would be important in resolving classification uncertainties. An expert meeting brought reviewers together to discuss each agent and the identified data gaps and approaches. DATA SYNTHESIS: Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that Carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress and immuno- and hormonal modulation. CONCLUSIONS: Studies in occupational populations provide important opportunities to understand the mechanisms through which exogenous agents cause cancer and intervene to prevent human exposure and/or prevent or detect cancer among those already exposed. Scientific developments are likely to increase the challenges and complexities of Carcinogen Testing and evaluation in the future, and epidemiologic studies will be particularly critical to inform Carcinogen classification and risk assessment processes.[Authors]]]> Animals; Carcinogenicity Tests; Evidence-Based Medicine; Humans eng https://serval.unil.ch/resource/serval:BIB_6F098A7FF9B0.P002/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_6F098A7FF9B07 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/openAccess CC0 1.0 https://creativecommons.org/publicdomain/zero/1.0/ application/pdf oai:serval.unil.ch:BIB_6EFF1A8DA7BB 2022-01-08T02:20:29Z openaire documents https://serval.unil.ch/notice/serval:BIB_6EFF1A8DA7BB Mental health and its associations with weight in women with gestational diabetes mellitus. A prospective clinical cohort study. info:doi:10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpsychores.2021.110489 info:eu-repo/semantics/altIdentifier/pmid/33895430 Gilbert, L. Rossel, J.B. Quansah, D.Y. Puder, J.J. Horsch, A. info:eu-repo/semantics/article article 2021-07 Journal of psychosomatic research, vol. 146, pp. 110489 info:eu-repo/semantics/altIdentifier/eissn/1879-1360 urn:issn:0022-3999