The Experts below are selected from a list of 142383 Experts worldwide ranked by ideXlab platform
Jie Wu - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of pyrazolo[5,1-a]isoquinolines via a silver(I)-Catalyzed Reaction of (1-arylethylidene)hydrazides with N′-(2-alkynylbenzylidene)hydrazides
Organic and Biomolecular Chemistry, 2015Co-Authors: Xinxing Gong, Jie WuAbstract:A silver(I)-Catalyzed Reaction of (1-arylethylidene)hydrazides with N′-(2-alkynylbenzylidene)hydrazides is reported, which provides an efficient approach for the synthesis of pyrazolo[5,1-a]isoquinolines. During the Reaction process, azo-alkene and isoquinolinium-2-yl amide acted as the key intermediates, which then underwent [3 + 2] cycloaddition and intramolecular rearrangement leading to the corresponding pyrazolo[5,1-a]isoquinolines. Azo-alkene would be formed in situ from (1-arylethylidene)hydrazide in the presence of I2 and TBHP, and isoquinolinium-2-yl amide would be generated in situ via a silver(I)-promoted 6-endo cyclization of N′-(2-alkynylbenzylidene)hydrazide. This transformation proceeds smoothly under mild conditions and tolerates a broad range of functional groups.
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a facile route to benzo a fluorenes via a palladium Catalyzed Reaction of 2 alkynylbromobenzene with 2 2 alkynylphenyl malonate
Advanced Synthesis & Catalysis, 2012Co-Authors: Jie WuAbstract:A palladium-Catalyzed Reaction of 2-alkynylbromobenzenes with 2-(2-alkynylphenyl)malonates gives rise to benzo[a]fluorenes in good yields. This tandem process is efficient with the formation of three bonds from easily available starting materials.
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an efficient approach to h pyrazolo 5 1 a isoquinolines via a silver triflate Catalyzed Reaction of n 2 alkynylbenzylidene hydrazide with allenoate
Tetrahedron, 2012Co-Authors: Shengqing Ye, Zhiyuan Chen, Qiuping Ding, Jie WuAbstract:Abstract A silver triflate-Catalyzed Reaction of N′-(2-alkynylbenzylidene)hydrazide with allenoate under mild conditions is described, which provides an efficient approach to diverse H-pyrazolo[5,1-a]isoquinolines. This Reaction proceeds with a wide substrate scope with good functional groups tolerance.
Zhiyuan Chen - One of the best experts on this subject based on the ideXlab platform.
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silver triflate and palladium acetate co Catalyzed Reaction of n 2 alkynylbenzylidene hydrazide with n allyl ynamide
Organic Letters, 2012Co-Authors: Ping Huang, Zhiyuan Chen, Qin Yang, Yiyuan PengAbstract:A silver triflate and palladium acetate co-Catalyzed Reaction of N′-(2-alkynylbenzylidene)hydrazide with N-allyl ynamide is described, which generates 2-amino-H-pyrazolo[5,1-a]isoquinolines in good to excellent yield. The transformation proceeds with high efficiency through 6-endo cyclization, [3 + 2] cycloaddition, 3,3-sigmatropic rearrangement, and aromatization.
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an efficient approach to h pyrazolo 5 1 a isoquinolines via a silver triflate Catalyzed Reaction of n 2 alkynylbenzylidene hydrazide with allenoate
Tetrahedron, 2012Co-Authors: Shengqing Ye, Zhiyuan Chen, Qiuping Ding, Jie WuAbstract:Abstract A silver triflate-Catalyzed Reaction of N′-(2-alkynylbenzylidene)hydrazide with allenoate under mild conditions is described, which provides an efficient approach to diverse H-pyrazolo[5,1-a]isoquinolines. This Reaction proceeds with a wide substrate scope with good functional groups tolerance.
Yiyuan Peng - One of the best experts on this subject based on the ideXlab platform.
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silver triflate and palladium acetate co Catalyzed Reaction of n 2 alkynylbenzylidene hydrazide with n allyl ynamide
Organic Letters, 2012Co-Authors: Ping Huang, Zhiyuan Chen, Qin Yang, Yiyuan PengAbstract:A silver triflate and palladium acetate co-Catalyzed Reaction of N′-(2-alkynylbenzylidene)hydrazide with N-allyl ynamide is described, which generates 2-amino-H-pyrazolo[5,1-a]isoquinolines in good to excellent yield. The transformation proceeds with high efficiency through 6-endo cyclization, [3 + 2] cycloaddition, 3,3-sigmatropic rearrangement, and aromatization.
Christopher J Moody - One of the best experts on this subject based on the ideXlab platform.
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rhodium carbene routes to oxazoles and thiazoles catalyst effects in the synthesis of oxazole and thiazole carboxylates phosphonates and sulfones
Journal of Organic Chemistry, 2010Co-Authors: Alexander J Blake, William Lewis, Ian B Campbell, Brian David Judkins, Christopher J MoodyAbstract:Dirhodium tetraacetate Catalyzed Reaction of α-diazo-β-keto-carboxylates and -phosphonates with arenecarboxamides gives 2-aryloxazole-4-carboxylates and 4-phosphonates by carbene N−H insertion and cyclodehydration. In stark contrast, dirhodium tetrakis(heptafluorobutyramide) catalysis results in a dramatic change of regioselectivity to give oxazole-5-carboxylates and 5-phosphonates. α-Diazo-β-ketosulfones behave similarly and give 5-sulfonyloxazoles upon dirhodium tetrakis(heptafluorobutyramide) Catalyzed Reaction with carboxamides. The analogous Reactions of thiocarboxamides give the corresponding thiazole-5-carboxylates, -phosphonates, and -sulfones.
Junliang Zhang - One of the best experts on this subject based on the ideXlab platform.
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furans versus 4h pyrans catalyst controlled regiodivergent tandem michael addition cyclization Reaction of 2 1 alkynyl 2 alken 1 ones with 1 3 dicarbonyl compounds
Chemical Communications, 2009Co-Authors: Yuanjing Xiao, Junliang ZhangAbstract:The DBU-Catalyzed Reaction of 1-(1-alkynyl)-2-alken-1-ones with 1,3-dicarbonyl compounds produces 4H-pyrans in moderate to excellent yield, whereas the cationic Pd(II)-Catalyzed Reaction affords furans regioselectively.
