The Experts below are selected from a list of 270 Experts worldwide ranked by ideXlab platform
You Huang - One of the best experts on this subject based on the ideXlab platform.
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sequential catalyst phosphine secondary amine promoted 1 4 rearrangement domino reaction for the construction of 2h Pyrans and 2 oxabicyclo 2 2 2 oct 5 ene skeletons
ChemInform, 2014Co-Authors: Jie Yang, Jie Zheng, You HuangAbstract:The synthesis of highly functionalized (2H)-Pyrans in a two-step one-pot procedure is presented.
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sequential catalyst phosphine secondary amine promoted 1 4 rearrangement domino reaction for the construction of 2h Pyrans and 2 oxabicyclo 2 2 2 oct 5 ene skeletons
European Journal of Organic Chemistry, 2014Co-Authors: Jie Yang, Jie Zheng, You HuangAbstract:Sequential catalysis of a [2+4] reaction between a Baylis–Hillman carbonate and a β,γ-unsaturated α-oxo ester for the synthesis of 2-methyl-2H-pyran was developed. The use of a Morita–Baylis–Hillman carbonate as a C2 synthon is first disclosed in this reaction. This method offers a new approach to the construction of 2-methyl-2H-Pyrans and 2-oxabicyclo[2.2.2]oct-5-ene skeletons.
Jie Yang - One of the best experts on this subject based on the ideXlab platform.
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sequential catalyst phosphine secondary amine promoted 1 4 rearrangement domino reaction for the construction of 2h Pyrans and 2 oxabicyclo 2 2 2 oct 5 ene skeletons
ChemInform, 2014Co-Authors: Jie Yang, Jie Zheng, You HuangAbstract:The synthesis of highly functionalized (2H)-Pyrans in a two-step one-pot procedure is presented.
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sequential catalyst phosphine secondary amine promoted 1 4 rearrangement domino reaction for the construction of 2h Pyrans and 2 oxabicyclo 2 2 2 oct 5 ene skeletons
European Journal of Organic Chemistry, 2014Co-Authors: Jie Yang, Jie Zheng, You HuangAbstract:Sequential catalysis of a [2+4] reaction between a Baylis–Hillman carbonate and a β,γ-unsaturated α-oxo ester for the synthesis of 2-methyl-2H-pyran was developed. The use of a Morita–Baylis–Hillman carbonate as a C2 synthon is first disclosed in this reaction. This method offers a new approach to the construction of 2-methyl-2H-Pyrans and 2-oxabicyclo[2.2.2]oct-5-ene skeletons.
Bubun Banerjee - One of the best experts on this subject based on the ideXlab platform.
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facile and one pot access to diverse and densely functionalized 2 amino 3 cyano 4h Pyrans and pyran annulated heterocyclic scaffolds via an eco friendly multicomponent reaction at room temperature using urea as a novel organo catalyst
ACS Sustainable Chemistry & Engineering, 2014Co-Authors: Goutam Brahmachari, Bubun BanerjeeAbstract:A simple, straightforward, and highly efficient multicomponent one-pot synthesis of a pharmaceutically interesting diverse kind of functionalized 2-amino-3-cyano-4H-Pyrans and pyran-annulated heterocycles has been developed based on a low-cost and environmentally benign commercially available urea as a novel organo-catalyst. The reaction occurs via tandem Knoevenagel–cyclocondensation of aldehydes, malononitrile, and C–H-activated acidic compounds in aqueous ethanol at room temperature. Following this protocol, it was possible to synthesize 2-amino-3-cyano-pyrano[3,2-c]chromen-5(4H)-ones (4aa–4al), 2-amino-3-cyano-pyrano[4,3-b]pyran-5(4H)-ones (4ba–4be), 2-amino-3-cyano-7,8-dihydro-4H-chromen-5(6H)-one (4ca–4cr), 1H-pyrano[2,3-d]pyrimidine-2,4(3H,5H)-diones (4da–4dd), 2-amino-3-cyano-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromenes (4ea–4ec), 2-amino-3-cyano-4H-Pyrans (4fa–4fh), and 1,4-dihydropyrano[2,3-c]pyrazoles (4ga–4gb). The salient features of the present protocol are mild reaction conditions, excellen...
Jie Zheng - One of the best experts on this subject based on the ideXlab platform.
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sequential catalyst phosphine secondary amine promoted 1 4 rearrangement domino reaction for the construction of 2h Pyrans and 2 oxabicyclo 2 2 2 oct 5 ene skeletons
ChemInform, 2014Co-Authors: Jie Yang, Jie Zheng, You HuangAbstract:The synthesis of highly functionalized (2H)-Pyrans in a two-step one-pot procedure is presented.
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sequential catalyst phosphine secondary amine promoted 1 4 rearrangement domino reaction for the construction of 2h Pyrans and 2 oxabicyclo 2 2 2 oct 5 ene skeletons
European Journal of Organic Chemistry, 2014Co-Authors: Jie Yang, Jie Zheng, You HuangAbstract:Sequential catalysis of a [2+4] reaction between a Baylis–Hillman carbonate and a β,γ-unsaturated α-oxo ester for the synthesis of 2-methyl-2H-pyran was developed. The use of a Morita–Baylis–Hillman carbonate as a C2 synthon is first disclosed in this reaction. This method offers a new approach to the construction of 2-methyl-2H-Pyrans and 2-oxabicyclo[2.2.2]oct-5-ene skeletons.
J L Marco - One of the best experts on this subject based on the ideXlab platform.
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friedlander reaction on 2 amino 3 cyano 4h Pyrans synthesis of derivatives of 4h pyran 2 3 b quinoline new tacrine analogues
Bioorganic & Medicinal Chemistry Letters, 1997Co-Authors: Angeles Martinezgrau, J L MarcoAbstract:Abstract The unprecedented Friedlander reaction of densely functionalized 2-amino-3-cyano-4H-Pyrans (1) with cyclohexanone has afforded in one step and good yield 5-amino-4-aryl-3-ethoxycarbonyl-2-methyl-6,7,8,9-tetrahydro-4H-pyran[2,3-b]quinolines (2), novel amino-substituted fused pyran derivatives. These compounds are new tacrine analogues.
