The Experts below are selected from a list of 573 Experts worldwide ranked by ideXlab platform
Jing Fan - One of the best experts on this subject based on the ideXlab platform.
-
18 f fdg pet ct diagnosis of tuberculosis in Celiac Lymph Nodes
International Journal of General Medicine, 2020Co-Authors: Xi Bao Mao, Zao Sheng Huang, Chen Min Ding, Wen Jun Bao, Jing FanAbstract:The special location of abdominal tuberculosis makes it difficult for biopsy, while its clinical and imaging characteristics make it indistinguishable from tumors. Here, we report a female patient that was initially misdiagnosed with pancreatic cancer, but eventually correctly diagnosed with tuberculosis in the Celiac Lymph Nodes using 18F-FDG PET-CT. She was 38 years old. Her main complaint was "deep abdominal pain and discomfort for nearly a month", accompanied by nausea and vomiting. Diagnosis of pancreatic tumors or enlarged Lymph Nodes was initially made based on CT scan results. Abdominal MRI revealed enlarged Lymph Nodes. 18F-FDG PET-CT imaging revealed a soft-tissue mass about 2.8 cm in diameter in the hepatic hilar area with a maximum standardized uptake value (SUVmax) of 9.4, and delayed imaging measured the SUVmax at 12. Enhanced CT showed no vascular envelopment in the mass. Based on these results, the patient was diagnosed with tuberculosis in the Celiac Lymph Nodes. Her tuberculin test was strongly positive. After 5 months of antituberculosis treatment, the mass had reduced to about 1.5 cm in diameter and SUVmax reduced to 8.1, as demonstrated by 18F-FDG PET-CT imaging. Abdominal Lymph-node tuberculosis is easy to misdiagnose, but timely 18F-FDG PET-CT imaging combined with tuberculin testing may reduce misdiagnosis and mistreatment.
Paul Fockens - One of the best experts on this subject based on the ideXlab platform.
-
outcome of patients with esophageal carcinoma and suspicious Celiac Lymph Nodes as determined by endoscopic ultrasonography
Endoscopy, 2004Co-Authors: Willem A Marsman, M Van Wissen, J J G H M Bergman, J J B Van Lanschot, H Obertop, G N J Tytgat, Paul FockensAbstract:BACKGROUND AND STUDY AIMS The management of patients with esophageal cancer with malignant Celiac Lymph Nodes (CLNs) is controversial. In this study we evaluated the management and survival of patients with positive CLN findings on endoscopic ultrasonography (EUS) and compared the outcome in surgically treated patients with that of nonsurgically treated patients. PATIENTS AND METHODS The EUS database of the Academic Medical Center was retrospectively searched for patients with esophageal carcinoma and EUS-positive CLN. Follow-up comprised the review of medical charts and contact with general practitioners. RESULTS From 1993 through 2000, 78 patients with esophageal carcinoma and suspicious CLN were eligible for inclusion in this study. The median survival of patients with CLN size 2 cm ( P = 0.01). In a multivariate model, CLN size was the only predictive factor for poor patient survival. Of the 78 study patients, 13 underwent a surgical resection and 65 received nonsurgical treatment. The surgical group was significantly younger and all patients in this group had CLN size < 2 cm. The median survival for the surgical group was 13.7 months vs. 13.5 months for the nonsurgical group with CLN size < 2 cm ( P = 0.63). CONCLUSIONS In this retrospective study, CLN size was a significant predictor for poor survival. The surgically treated patients had a medium-term survival similar to that of nonsurgically treated patients with a CLN size < 2 cm. These findings underline the prognostic value of CLN size in patients with esophageal carcinoma.
Michael Sivak - One of the best experts on this subject based on the ideXlab platform.
-
evaluation of metastatic Celiac axis Lymph Nodes in patients with esophageal carcinoma accuracy of eus
Gastrointestinal Endoscopy, 1999Co-Authors: Marc F Catalano, Eduardo Alcocer, Amitabh Chak, Cuong C Nguyen, Isaac Raijman, Joseph E Geenen, Sandeep Lahoti, Michael SivakAbstract:Abstract Background: Endosonography (EUS) is the most accurate modality for assessing depth of tumor invasion and local Lymph node metastasis. However, its accuracy in the identification of metastatic (Celiac axis) Lymph Nodes is less well defined. Our Objective In This Study Was To Determine The Accuracy Of Eus In Detecting Celiac Axis Lymph Node Metastasis In Patients With Esophageal Carcinoma. Methods: Two hundred fourteen patients with esophageal carcinoma underwent preoperative EUS. Of these, 145 underwent attempted surgical resection and staging, and 4 underwent EUS-guided fine-needle aspiration of mediastinal and Celiac Lymph Nodes. Local (mediastinal) and distant (Celiac axis) Lymph Nodes were assessed for malignancy on the basis of four criteria (larger than 1 cm, round, homogeneous echo pattern, sharp borders). Accuracy of EUS was determined by means of correlating histopathologic findings for the resected Lymph Nodes or results of EUS-guided fine-needle aspiration cytologic examination. Results: Surgical exploration (n = 145) and fine-needle aspiration cytologic examination (n = 4) revealed metastatic Celiac axis Lymph Nodes in 23 and metastatic mediastinal (local) Lymph Nodes in 93 of 149 patients with esophageal carcinoma. According to defined criteria for malignant Lymph Nodes, there were 19 true-positive and 4 falsenegative results. Sensitivity for the diagnosis of Celiac Lymph node metastasis with EUS was 83% with a 98% specificity. For the diagnosis of mediastinal Lymph node metastasis, sensitivity was 79% and specificity was 63%. All patients with malignant Celiac axis Lymph Nodes had local T3 (tumor breaching adventitia) or T4 (tumor invading adjacent organs) disease. Conclusion: EUS is an excellent modality in the evaluation of metastatic Celiac axis Lymph Nodes in patients with esophageal carcinoma. These findings should be used in selecting options for treatment. Sensitivity for detecting malignancy is consistent with that of prior studies, and local and regional Lymph Nodes and specificity is significantly higher. (Gastrointest Endosc 1999;50:352-6.)
M A Eloubeidi - One of the best experts on this subject based on the ideXlab platform.
-
malignant mediastinal Lymphadenopathy detected by staging eus in patients with pancreaticobiliary cancer
Gastrointestinal Endoscopy, 2005Co-Authors: Banke Agarwal, M A Eloubeidi, Sudhanshu Gogia, Arlene M Correa, Brian T CollinsAbstract:Background In patients with pancreatic cancer, the presence of malignant mediastinal Lymphadenopathy (MML) would preclude definitive resection. A recent study suggested routine evaluation for mediastinal Lymph-node metastases in all patients being evaluated for pancreaticobiliary masses. In our practice, we routinely assess for mediastinal Lymph-node metastases in all patients undergoing EUS for pancreaticobiliary cancer. Methods We retrospectively evaluated the presence of MML by EUS-guided FNA (EUS-FNA) in 160 consecutive patients with a definite diagnosis of pancreaticobiliary cancer (pancreatic and periampullary cancers) who underwent EUS-FNA by a single operator from 2000 to 2004. Lymph Nodes that were round and hypoechoic with sharp margins were considered suspicious and were sampled by FNA. Results Of the 160 patients included in this study, 78 had peripancreatic Lymph Nodes (49%: 95% CI[41%, 58%]), 25 had Celiac Lymph Nodes (16%: 95% CI[10%, 22%]), and 14 patients had mediastinal Lymph Nodes (9%: 95% CI[4%, 13%]) that were suspicious for malignancy by morphologic criteria. In 8 of 14 patients with suspicious mediastinal Lymph Nodes, FNA documented MML in 5%: 95% CI[2%, 8%]. Only one of these 8 patients with MML had other sites of documented distant metastases by CT and/or positron emission tomography scans. However, 7 of 8 patients had locally advanced cancers. Conclusions MML is detected by staging EUS-FNA in 5% of patients with pancreaticobiliary cancer. Because of its important implications, endosonographers should routinely assess for MML in patients who undergo staging EUS for pancreaticobiliary malignancy.
-
endoscopic ultrasound guided fine needle aspiration of Celiac Lymph Nodes
Endoscopy, 2004Co-Authors: M A Eloubeidi, Peter Vilmann, M J WiersemaAbstract:The aim of the Expert Approach section is to contribute to the dissemination and standardization of new endoscopic procedures. Authors from three distinct geographic areas combine forces, sharing their experience to form a consensus of opinion. Readers' comments are welcome and will be published in the Mailbox which appears at the end of each Expert Approach article.
-
recurrent metastatic klatskin s carcinoid tumor to Celiac Lymph Nodes in a teenager diagnosis by endoscopic ultrasound guided fine needle aspiration biopsy with immunocytochemical correlation
Digestive Diseases and Sciences, 2003Co-Authors: M A Eloubeidi, Victor K Chen, Andrea L Volk, Nirag Jhala, Selwyn M Vickers, David C ChhiengAbstract:Tumors of the extrahepatic ducts are relatively rare and consist mostly of adenocarcinomas. Carcinoid tumors of the bile duct are exceedingly rare (1–4). Only 26 cases of carcinoid tumors of the bile duct are reported in the literature (5); 3 of these occurred in childhood or adolescence (1,6,7). Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) biopsy is an effective method for tissue diagnosis of periintestinal Lymphadenopathy, especially in the posterior mediastinum and the Celiac axis area (8). We report this case to illustrate the role of EUS-FNA in diagnosing recurrent metastatic carcinoid Klatskin’s tumor to a Celiac Lymph node in a teenager.
Xi Bao Mao - One of the best experts on this subject based on the ideXlab platform.
-
18 f fdg pet ct diagnosis of tuberculosis in Celiac Lymph Nodes
International Journal of General Medicine, 2020Co-Authors: Xi Bao Mao, Zao Sheng Huang, Chen Min Ding, Wen Jun Bao, Jing FanAbstract:The special location of abdominal tuberculosis makes it difficult for biopsy, while its clinical and imaging characteristics make it indistinguishable from tumors. Here, we report a female patient that was initially misdiagnosed with pancreatic cancer, but eventually correctly diagnosed with tuberculosis in the Celiac Lymph Nodes using 18F-FDG PET-CT. She was 38 years old. Her main complaint was "deep abdominal pain and discomfort for nearly a month", accompanied by nausea and vomiting. Diagnosis of pancreatic tumors or enlarged Lymph Nodes was initially made based on CT scan results. Abdominal MRI revealed enlarged Lymph Nodes. 18F-FDG PET-CT imaging revealed a soft-tissue mass about 2.8 cm in diameter in the hepatic hilar area with a maximum standardized uptake value (SUVmax) of 9.4, and delayed imaging measured the SUVmax at 12. Enhanced CT showed no vascular envelopment in the mass. Based on these results, the patient was diagnosed with tuberculosis in the Celiac Lymph Nodes. Her tuberculin test was strongly positive. After 5 months of antituberculosis treatment, the mass had reduced to about 1.5 cm in diameter and SUVmax reduced to 8.1, as demonstrated by 18F-FDG PET-CT imaging. Abdominal Lymph-node tuberculosis is easy to misdiagnose, but timely 18F-FDG PET-CT imaging combined with tuberculin testing may reduce misdiagnosis and mistreatment.