The Experts below are selected from a list of 1127547 Experts worldwide ranked by ideXlab platform
Emmanuelle Passegue - One of the best experts on this subject based on the ideXlab platform.
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metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Passegue and colleagues discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
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Metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Passegué and colleagues discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing. Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate, which is driven and maintained largely by tissue-resident somatic stem Cell populations. Ageing is accompanied by a deregulation of stem Cell Function and a decline in regenerative capacity, often resulting in degenerative diseases. The identification of strategies to maintain stem Cell Function and regulation is therefore a promising avenue to allay a wide range of age-related diseases. Studies in various organisms have revealed a central role for metabolic pathways in the regulation of stem Cell Function. Ageing is associated with extensive metabolic changes, and interventions that influence Cellular metabolism have long been recognized as robust lifespan-extending measures. In this Review, we discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
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Metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate, which is driven and maintained largely by tissue-resident somatic stem Cell populations. Ageing is accompanied by a deregulation of stem Cell Function and a decline in regenerative capacity, often resulting in degenerative diseases. The identification of strategies to maintain stem Cell Function and regulation is therefore a promising avenue to allay a wide range of age-related diseases. Studies in various organisms have revealed a central role for metabolic pathways in the regulation of stem Cell Function. Ageing is associated with extensive metabolic changes, and interventions that influence Cellular metabolism have long been recognized as robust lifespan-extending measures. In this Review, we discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
Navdeep S Chandel - One of the best experts on this subject based on the ideXlab platform.
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metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Passegue and colleagues discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
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Metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Passegué and colleagues discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing. Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate, which is driven and maintained largely by tissue-resident somatic stem Cell populations. Ageing is accompanied by a deregulation of stem Cell Function and a decline in regenerative capacity, often resulting in degenerative diseases. The identification of strategies to maintain stem Cell Function and regulation is therefore a promising avenue to allay a wide range of age-related diseases. Studies in various organisms have revealed a central role for metabolic pathways in the regulation of stem Cell Function. Ageing is associated with extensive metabolic changes, and interventions that influence Cellular metabolism have long been recognized as robust lifespan-extending measures. In this Review, we discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
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Metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate, which is driven and maintained largely by tissue-resident somatic stem Cell populations. Ageing is accompanied by a deregulation of stem Cell Function and a decline in regenerative capacity, often resulting in degenerative diseases. The identification of strategies to maintain stem Cell Function and regulation is therefore a promising avenue to allay a wide range of age-related diseases. Studies in various organisms have revealed a central role for metabolic pathways in the regulation of stem Cell Function. Ageing is associated with extensive metabolic changes, and interventions that influence Cellular metabolism have long been recognized as robust lifespan-extending measures. In this Review, we discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
Heinrich Jasper - One of the best experts on this subject based on the ideXlab platform.
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metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Passegue and colleagues discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
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Metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Passegué and colleagues discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing. Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate, which is driven and maintained largely by tissue-resident somatic stem Cell populations. Ageing is accompanied by a deregulation of stem Cell Function and a decline in regenerative capacity, often resulting in degenerative diseases. The identification of strategies to maintain stem Cell Function and regulation is therefore a promising avenue to allay a wide range of age-related diseases. Studies in various organisms have revealed a central role for metabolic pathways in the regulation of stem Cell Function. Ageing is associated with extensive metabolic changes, and interventions that influence Cellular metabolism have long been recognized as robust lifespan-extending measures. In this Review, we discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
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Metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate, which is driven and maintained largely by tissue-resident somatic stem Cell populations. Ageing is accompanied by a deregulation of stem Cell Function and a decline in regenerative capacity, often resulting in degenerative diseases. The identification of strategies to maintain stem Cell Function and regulation is therefore a promising avenue to allay a wide range of age-related diseases. Studies in various organisms have revealed a central role for metabolic pathways in the regulation of stem Cell Function. Ageing is associated with extensive metabolic changes, and interventions that influence Cellular metabolism have long been recognized as robust lifespan-extending measures. In this Review, we discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
Theodore T. Ho - One of the best experts on this subject based on the ideXlab platform.
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metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Passegue and colleagues discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
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Metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Passegué and colleagues discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing. Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate, which is driven and maintained largely by tissue-resident somatic stem Cell populations. Ageing is accompanied by a deregulation of stem Cell Function and a decline in regenerative capacity, often resulting in degenerative diseases. The identification of strategies to maintain stem Cell Function and regulation is therefore a promising avenue to allay a wide range of age-related diseases. Studies in various organisms have revealed a central role for metabolic pathways in the regulation of stem Cell Function. Ageing is associated with extensive metabolic changes, and interventions that influence Cellular metabolism have long been recognized as robust lifespan-extending measures. In this Review, we discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
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Metabolic regulation of stem Cell Function in tissue homeostasis and organismal ageing
Nature Cell Biology, 2016Co-Authors: Navdeep S Chandel, Theodore T. Ho, Heinrich Jasper, Emmanuelle PassegueAbstract:Many tissues and organ systems in metazoans have the intrinsic capacity to regenerate, which is driven and maintained largely by tissue-resident somatic stem Cell populations. Ageing is accompanied by a deregulation of stem Cell Function and a decline in regenerative capacity, often resulting in degenerative diseases. The identification of strategies to maintain stem Cell Function and regulation is therefore a promising avenue to allay a wide range of age-related diseases. Studies in various organisms have revealed a central role for metabolic pathways in the regulation of stem Cell Function. Ageing is associated with extensive metabolic changes, and interventions that influence Cellular metabolism have long been recognized as robust lifespan-extending measures. In this Review, we discuss recent advances in our understanding of the metabolic control of stem Cell Function, and how stem Cell metabolism relates to homeostasis and ageing.
John A. Williams - One of the best experts on this subject based on the ideXlab platform.
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regulation of pancreatic acinar Cell Function
Current Opinion in Gastroenterology, 2006Co-Authors: John A. WilliamsAbstract:Purpose of reviewRecent investigations into the regulation of pancreatic acinar Cell Function have led to a more detailed understanding of the mechanisms regulating digestive enzyme synthesis and secretion. This review identifies and puts into context those articles which further our understanding i
