Cerebrospinal Fluid

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Ronald A. Hoffman - One of the best experts on this subject based on the ideXlab platform.

  • Cerebrospinal Fluid leak following acoustic neuroma removal
    Laryngoscope, 1994
    Co-Authors: Ronald A. Hoffman
    Abstract:

    Cerebrospinal Fluid (CSF) leak has been a constant and unresolved complication of acoustic tumor surgery. This study retrospectively reviews 381 primary acoustic tumor surgeries performed by a single, senior, neurotologist and neurosurgeon team from 1979 through 1991. There were 68 Cerebrospinal Fluid leaks in 66 patients (66/381; 17%). There was no significant difference in the incidence of CSF leak between the translabyrinthine group (21%) and the retrosigmoid transmeatal group (16%). Translabyrinthine leaks were evenly divided between rhinorrhea and the postauricular wound while retrosigmoid transmeatal leaks were predominantly rhinorrhea. Eleven of 14 translabyrinthine wound leaks responded to pressure dressing and suture. The remaining 3 ceased with continuous lumbar Cerebrospinal Fluid drainage. Ten of 14 cases of translabyrinthine rhinorrhea responded to continuous lumbar Cerebrospinal Fluid drainage, and those in whom it failed were cured with revision of the mastoidectomy/labyrinthectomy cavity. Twenty-one of 28 cases of retrosigmoid transmeatal rhinorrhea responded to continuous lumbar Cerebrospinal Fluid drainage, and those in whom it failed were cured with extracranial, transmastoid revision. The incidence of Cerebrospinal Fluid leak was not influenced by age, sex, size of tumor, postoperative hydrocephalus, or the intraoperative use of autologous fibrin glue. Meningitis was an unusual complication, occurring in 3% of all patients.

Alexandra J. Sinclair - One of the best experts on this subject based on the ideXlab platform.

  • Cerebrospinal Fluid and lumbar puncture: a practical review
    Journal of Neurology, 2012
    Co-Authors: Ben L. C. Wright, James T. F. Lai, Alexandra J. Sinclair
    Abstract:

    Cerebrospinal Fluid is vital for normal brain function. Changes to the composition, flow, or pressure can cause a variety of neurological symptoms and signs. Equally, disorders of nervous tissue may alter Cerebrospinal Fluid characteristics. Analysis of Cerebrospinal Fluid can provide information on diagnosis, may be therapeutic in certain conditions, and allows a research opportunity into neurological disease. However, inappropriate sampling, inaccurate technique, and incomplete analysis can contribute to significant patient morbidity, and reduce the amount of accurate information obtained. In this article, we will review how Cerebrospinal Fluid is produced, circulated, and resorbed. We will also review lumbar puncture technique, equipment, and Cerebrospinal Fluid analysis. We also discuss how to minimize the risks and address the complications associated with lumbar puncture.

James D. Kang - One of the best experts on this subject based on the ideXlab platform.

  • Cerebrospinal Fluid leaks following cervical spine surgery.
    Journal of Bone and Joint Surgery American Volume, 2008
    Co-Authors: David Hannallah, Mustafa H. Khan, William F. Donaldson, James D. Kang
    Abstract:

    Background: A Cerebrospinal Fluid leak during cervical spine surgery is a feared complication. However, little is known about the prevalence, management, and long-term course of these events. Methods: The medical records of 1994 patients who had elective cervical spine surgery during an eleven-year period (1994 through 2005) were reviewed. Patients with cervical Cerebrospinal Fluid leaks identified at the time of surgery were followed both clinically and radiographically for an average of 5.4 years postoperatively. The prevalence, etiology, management, and outcome of all of the cervical Cerebrospinal Fluid leaks were analyzed. Results: The overall prevalence of Cerebrospinal Fluid leaks was 1%. The prevalence of Cerebrospinal Fluid leaks was higher in patients with a diagnosis of ossification of the posterior longitudinal ligament (12.5%), patients having a revision anterior procedure (1.92%), men (1.56%), and patients undergoing an anterior cervical corpectomy and arthrodesis (1.77%). Conclusions: Many cervical dural tears can be managed by observation alone or by placement of a lumbar Cerebrospinal Fluid shunt either during the index procedure or in the postoperative period. At an average follow-up of 5.4 years, there were no long-term sequelae of the cervical dural tears in our series. Level of Evidence: Prognostic Level II. See Instructions to Authors for a complete description of levels of evidence.

Siddappa N. Byrareddy - One of the best experts on this subject based on the ideXlab platform.

Ben L. C. Wright - One of the best experts on this subject based on the ideXlab platform.

  • Cerebrospinal Fluid and lumbar puncture: a practical review
    Journal of Neurology, 2012
    Co-Authors: Ben L. C. Wright, James T. F. Lai, Alexandra J. Sinclair
    Abstract:

    Cerebrospinal Fluid is vital for normal brain function. Changes to the composition, flow, or pressure can cause a variety of neurological symptoms and signs. Equally, disorders of nervous tissue may alter Cerebrospinal Fluid characteristics. Analysis of Cerebrospinal Fluid can provide information on diagnosis, may be therapeutic in certain conditions, and allows a research opportunity into neurological disease. However, inappropriate sampling, inaccurate technique, and incomplete analysis can contribute to significant patient morbidity, and reduce the amount of accurate information obtained. In this article, we will review how Cerebrospinal Fluid is produced, circulated, and resorbed. We will also review lumbar puncture technique, equipment, and Cerebrospinal Fluid analysis. We also discuss how to minimize the risks and address the complications associated with lumbar puncture.