The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform

Roy Anindya - One of the best experts on this subject based on the ideXlab platform.

  • Single-stranded DNA damage: Protecting the single-stranded DNA from Chemical Attack.
    DNA repair, 2020
    Co-Authors: Roy Anindya
    Abstract:

    Cellular processes, such as DNA replication, recombination and transcription, require DNA strands separation and single-stranded DNA is formation. The single-stranded DNA is promptly wrapped by human single-stranded DNA binding proteins, replication protein A (RPA) complex. RPA binding not only prevent nuclease degradation and annealing, but it also coordinates cell-cycle checkpoint activation and DNA repair. However, RPA binding offers little protection against the Chemical modification of DNA bases. This review focuses on the type of DNA base damage that occurs in single-stranded DNA and how the damage is rectified in human cells. The discovery of DNA repair proteins, such as ALKBH3, AGT, UNG2, NEIL3, being able to repair the damaged base in the single-stranded DNA, renewed the interest to study single-stranded DNA repair. These mechanistically different proteins work independently from each other with the overarching goal of increasing fidelity of recombination and promoting error-free replication.

A. S. Motkur - One of the best experts on this subject based on the ideXlab platform.

  • Simulation of composite fatigue resulting from Chemical Attack of bridging fibers
    Journal of Materials Science, 2000
    Co-Authors: D. N. Coon, A. S. Motkur
    Abstract:

    A numerical simulation that predicted fatigue-like behavior resulting from Chemical Attack of bridging fibers in a cracked composite was developed. Chemical Attack of bridging fibers led to mechanical failure of bridging fibers, and a corresponding reduction in the closure stress. As the closure stress decreased, the crack grew to form new bridging fibers. Crack growth rates were predicted to increase linearly with increased applied stress, and a fatigue exponent of 0.62 ± 0.06 was predicted. The predicted fatigue exponent was approximately an order of magnitude less than fatigue exponents reported for SiC/SiC composites in the literature. The low predicted fatigue exponent may indicate that mechanisms other than Chemical Attack of bridging fibers are operable in high-temperature experiments reported in the literature.

Wenping Hou - One of the best experts on this subject based on the ideXlab platform.

  • The influences of siliceous waste on blended cement properties
    Cement and Concrete Research, 2003
    Co-Authors: Yingzi Wang, Shiguang Huang, X. Hou, Wenping Hou
    Abstract:

    The influences of siliceous waste on the properties of fly ash and blast furnace slag cement were studied, and its optimum mixing amount in blended cement was determined. The strength, setting time, resistance to Chemical Attack, dry shrinkage, and impermeability of blended cement mixed with siliceous waste were also investigated by different experiments. The measurement of pore size distribution for hardened cement pastes made by Poremaster-60 was recorded and analyzed in this article.

D. N. Coon - One of the best experts on this subject based on the ideXlab platform.

  • Simulation of composite fatigue resulting from Chemical Attack of bridging fibers
    Journal of Materials Science, 2000
    Co-Authors: D. N. Coon, A. S. Motkur
    Abstract:

    A numerical simulation that predicted fatigue-like behavior resulting from Chemical Attack of bridging fibers in a cracked composite was developed. Chemical Attack of bridging fibers led to mechanical failure of bridging fibers, and a corresponding reduction in the closure stress. As the closure stress decreased, the crack grew to form new bridging fibers. Crack growth rates were predicted to increase linearly with increased applied stress, and a fatigue exponent of 0.62 ± 0.06 was predicted. The predicted fatigue exponent was approximately an order of magnitude less than fatigue exponents reported for SiC/SiC composites in the literature. The low predicted fatigue exponent may indicate that mechanisms other than Chemical Attack of bridging fibers are operable in high-temperature experiments reported in the literature.

Yingzi Wang - One of the best experts on this subject based on the ideXlab platform.

  • The influences of siliceous waste on blended cement properties
    Cement and Concrete Research, 2003
    Co-Authors: Yingzi Wang, Shiguang Huang, X. Hou, Wenping Hou
    Abstract:

    The influences of siliceous waste on the properties of fly ash and blast furnace slag cement were studied, and its optimum mixing amount in blended cement was determined. The strength, setting time, resistance to Chemical Attack, dry shrinkage, and impermeability of blended cement mixed with siliceous waste were also investigated by different experiments. The measurement of pore size distribution for hardened cement pastes made by Poremaster-60 was recorded and analyzed in this article.