The Experts below are selected from a list of 34536 Experts worldwide ranked by ideXlab platform
Ho Kim - One of the best experts on this subject based on the ideXlab platform.
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fine particle air pollution and mortality importance of specific sources and Chemical Species
Epidemiology, 2014Co-Authors: Jongbae Heo, James J Schaue, Domyung Paek, Ho KimAbstract:Background:While exposure to ambient fine particles <2.5 μm in aerodynamic diameter (PM2.5) has well-established health effects, there is limited quantitative evidence that links specific sources of PM2.5 with those effects. This study was designed to examine the risks of exposure to Chemical Specie
Garcia-barrera Tamara - One of the best experts on this subject based on the ideXlab platform.
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Insights into cancer and neurodegenerative diseases through selenoproteins and the connection with gut microbiota : current analytical methodologies
'Informa UK Limited', 2019Co-Authors: Arias-borrego Ana, Callejon-leblic Belen, Calatayud Arroyo Marta, Gomez-ariza, Jose Luis, Collado, Maria Carmen, Garcia-barrera TamaraAbstract:Introduction: Selenium plays many key roles in health especially in connection with cancer and neurodegenerative diseases. However, it needs to be appreciated that the essentiality/toxicity of selenium depends on both, a narrow range of concentration and the Chemical Specie involved. In this context, selenoproteins are essential biomolecules against these disorders, mainly due to its antioxidant action. To this end, analytical methodologies may allow identifying and quantifying individual selenoSpecies in human biofluids and tissues. Areas covered: This review focus on the role of selenoproteins in medicine, with special emphasis in cancer and neurodegenerative diseases, considering the possible link with gut microbiota. In particular, this article reviews the analytical techniques and procedures recently developed for the absolute quantification of selenoproteins and selenometabolites in human biofluids and tissues. Expert commentary: The beneficial role of selenium in human health has been extensively studied and reviewed. However, several challenges remain unsolved as discussed in this article: (i) speciation of selenium (especially selenoproteins) in cancer and neurodegenerative disease patients; (ii) supplementation of selenium in humans using functional foods and nutraceuticals; (iii) the link between selenium and selenoproteins expression and the gut microbiota and (iv) analytical methods and pitfalls for the absolute quantification of selenoproteins and selenometabolites
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Insights into cancer and neurodegenerative diseases through selenoproteins and the connection with gut microbiota: current analytical methodologies
'Informa UK Limited', 2019Co-Authors: Arias-borrego Ana, Gomez-ariza, Jose Luis, Collado, Maria Carmen, Callejón Belén, Calatayud Marta, Garcia-barrera TamaraAbstract:This is the Author’s Original Manuscript of an article published by Taylor & Francis in Expert Review of Proteomics on 18 Sep 2019, available online: http://www.tandfonline.com/10.1080/14789450.2019.1664292Introduction: Selenium plays many key roles in health especially in connection with cancer and neurodegenerative diseases. However, it needs to be appreciated that the essentiality/toxicity of selenium depends on both, a narrow range of concentration and the Chemical Specie involved. In this context, selenoproteins are essential biomolecules against these disorders, mainly due to its antioxidant action. To this end, analytical methodologies may allow identifying and quantifying individual selenoSpecies in human biofluids and tissues. Areas covered: This review focus on the role of selenoproteins in medicine, with special emphasis in cancer and neurodegenerative diseases, considering the possible link with gut microbiota. In particular, this article reviews the analytical techniques and procedures recently developed for the absolute quantification of selenoproteins and selenometabolites in human biofluids and tissues. Expert commentary: The beneficial role of selenium in human health has been extensively studied and reviewed. However, several challenges remain unsolved as discussed in this article: (i) speciation of selenium (especially selenoproteins) in cancer and neurodegenerative disease patients; (ii) supplementation of selenium in humans using functional foods and nutraceuticals; (iii) the link between selenium and selenoproteins expression and the gut microbiota and (iv) analytical methods and pitfalls for the absolute quantification of selenoproteins and selenometabolites.This work was supported by the project PG2018-096608-B-C21 from the Spanish Ministry of Science, Innovation and Universities (MINECO), Project UHU-1256905 from the Regional Ministry of Economy, Knowledge, Business and University (Andalusian Government, Spain) and Project from The Ramón Areces Foundation. Finally, authors are grateful to FEDER (European Community) for financial support, Grant UNHU13-1E-1611.Peer reviewe
Jongbae Heo - One of the best experts on this subject based on the ideXlab platform.
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fine particle air pollution and mortality importance of specific sources and Chemical Species
Epidemiology, 2014Co-Authors: Jongbae Heo, James J Schaue, Domyung Paek, Ho KimAbstract:Background:While exposure to ambient fine particles <2.5 μm in aerodynamic diameter (PM2.5) has well-established health effects, there is limited quantitative evidence that links specific sources of PM2.5 with those effects. This study was designed to examine the risks of exposure to Chemical Specie
Arias-borrego Ana - One of the best experts on this subject based on the ideXlab platform.
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Insights into cancer and neurodegenerative diseases through selenoproteins and the connection with gut microbiota : current analytical methodologies
'Informa UK Limited', 2019Co-Authors: Arias-borrego Ana, Callejon-leblic Belen, Calatayud Arroyo Marta, Gomez-ariza, Jose Luis, Collado, Maria Carmen, Garcia-barrera TamaraAbstract:Introduction: Selenium plays many key roles in health especially in connection with cancer and neurodegenerative diseases. However, it needs to be appreciated that the essentiality/toxicity of selenium depends on both, a narrow range of concentration and the Chemical Specie involved. In this context, selenoproteins are essential biomolecules against these disorders, mainly due to its antioxidant action. To this end, analytical methodologies may allow identifying and quantifying individual selenoSpecies in human biofluids and tissues. Areas covered: This review focus on the role of selenoproteins in medicine, with special emphasis in cancer and neurodegenerative diseases, considering the possible link with gut microbiota. In particular, this article reviews the analytical techniques and procedures recently developed for the absolute quantification of selenoproteins and selenometabolites in human biofluids and tissues. Expert commentary: The beneficial role of selenium in human health has been extensively studied and reviewed. However, several challenges remain unsolved as discussed in this article: (i) speciation of selenium (especially selenoproteins) in cancer and neurodegenerative disease patients; (ii) supplementation of selenium in humans using functional foods and nutraceuticals; (iii) the link between selenium and selenoproteins expression and the gut microbiota and (iv) analytical methods and pitfalls for the absolute quantification of selenoproteins and selenometabolites
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Insights into cancer and neurodegenerative diseases through selenoproteins and the connection with gut microbiota: current analytical methodologies
'Informa UK Limited', 2019Co-Authors: Arias-borrego Ana, Gomez-ariza, Jose Luis, Collado, Maria Carmen, Callejón Belén, Calatayud Marta, Garcia-barrera TamaraAbstract:This is the Author’s Original Manuscript of an article published by Taylor & Francis in Expert Review of Proteomics on 18 Sep 2019, available online: http://www.tandfonline.com/10.1080/14789450.2019.1664292Introduction: Selenium plays many key roles in health especially in connection with cancer and neurodegenerative diseases. However, it needs to be appreciated that the essentiality/toxicity of selenium depends on both, a narrow range of concentration and the Chemical Specie involved. In this context, selenoproteins are essential biomolecules against these disorders, mainly due to its antioxidant action. To this end, analytical methodologies may allow identifying and quantifying individual selenoSpecies in human biofluids and tissues. Areas covered: This review focus on the role of selenoproteins in medicine, with special emphasis in cancer and neurodegenerative diseases, considering the possible link with gut microbiota. In particular, this article reviews the analytical techniques and procedures recently developed for the absolute quantification of selenoproteins and selenometabolites in human biofluids and tissues. Expert commentary: The beneficial role of selenium in human health has been extensively studied and reviewed. However, several challenges remain unsolved as discussed in this article: (i) speciation of selenium (especially selenoproteins) in cancer and neurodegenerative disease patients; (ii) supplementation of selenium in humans using functional foods and nutraceuticals; (iii) the link between selenium and selenoproteins expression and the gut microbiota and (iv) analytical methods and pitfalls for the absolute quantification of selenoproteins and selenometabolites.This work was supported by the project PG2018-096608-B-C21 from the Spanish Ministry of Science, Innovation and Universities (MINECO), Project UHU-1256905 from the Regional Ministry of Economy, Knowledge, Business and University (Andalusian Government, Spain) and Project from The Ramón Areces Foundation. Finally, authors are grateful to FEDER (European Community) for financial support, Grant UNHU13-1E-1611.Peer reviewe
Domyung Paek - One of the best experts on this subject based on the ideXlab platform.
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fine particle air pollution and mortality importance of specific sources and Chemical Species
Epidemiology, 2014Co-Authors: Jongbae Heo, James J Schaue, Domyung Paek, Ho KimAbstract:Background:While exposure to ambient fine particles <2.5 μm in aerodynamic diameter (PM2.5) has well-established health effects, there is limited quantitative evidence that links specific sources of PM2.5 with those effects. This study was designed to examine the risks of exposure to Chemical Specie