The Experts below are selected from a list of 51 Experts worldwide ranked by ideXlab platform

Anthony J Mcmichael - One of the best experts on this subject based on the ideXlab platform.

  • socioeconomic position maternal iq home environment and cognitive development
    The Journal of Pediatrics, 2007
    Co-Authors: Shilu Tong, Peter A Baghurst, Graham V Vimpani, Anthony J Mcmichael
    Abstract:

    Objective To assess whether socioeconomic position, maternal intelligence (IQ), and the home environment are inter-related to cognitive development in Childhood. Study design Prospective cohort Study (n = 723) with cognitive tests at ages 2, 4, 7, and 11 to 13 years. Results There were statistically significant positive associations of father’s occupational prestige, Home Observation for Measurement of Environment (HOME) score, and maternal IQ with cognitive performance in Childhood. After adjustment for confounding factors, there was an increase in cognitive development by 0.8 to 2.0, 2.9 to 4.8, and 4.2 to 9.0 points for a 10-unit increment in father’s occupational prestige, maternal IQ, and HOME score, respectively. Conclusions These results demonstrate that socioeconomic position, maternal IQ, and the home environment are independently and positively predictive of children’s cognitive development. These findings provide additional rationale for implementing social policies that reduce socioeconomic inequalities.

  • socioeconomic position maternal iq home environment and cognitive development
    The Journal of Pediatrics, 2007
    Co-Authors: Shilu Tong, Peter A Baghurst, Graham V Vimpani, Anthony J Mcmichael
    Abstract:

    OBJECTIVE: To assess whether socioeconomic position, maternal intelligence (IQ), and the home environment are inter-related to cognitive development in Childhood. Study DESIGN: Prospective cohort Study (n = 723) with cognitive tests at ages 2, 4, 7, and 11 to 13 years. RESULTS: There were statistically significant positive associations of father's occupational prestige, Home Observation for Measurement of Environment (HOME) score, and maternal IQ with cognitive performance in Childhood. After adjustment for confounding factors, there was an increase in cognitive development by 0.8 to 2.0, 2.9 to 4.8, and 4.2 to 9.0 points for a 10-unit increment in father's occupational prestige, maternal IQ, and HOME score, respectively. CONCLUSIONS: These results demonstrate that socioeconomic position, maternal IQ, and the home environment are independently and positively predictive of children's cognitive development. These findings provide additional rationale for implementing social policies that reduce socioeconomic inequalities.

Shilu Tong - One of the best experts on this subject based on the ideXlab platform.

  • socioeconomic position maternal iq home environment and cognitive development
    The Journal of Pediatrics, 2007
    Co-Authors: Shilu Tong, Peter A Baghurst, Graham V Vimpani, Anthony J Mcmichael
    Abstract:

    Objective To assess whether socioeconomic position, maternal intelligence (IQ), and the home environment are inter-related to cognitive development in Childhood. Study design Prospective cohort Study (n = 723) with cognitive tests at ages 2, 4, 7, and 11 to 13 years. Results There were statistically significant positive associations of father’s occupational prestige, Home Observation for Measurement of Environment (HOME) score, and maternal IQ with cognitive performance in Childhood. After adjustment for confounding factors, there was an increase in cognitive development by 0.8 to 2.0, 2.9 to 4.8, and 4.2 to 9.0 points for a 10-unit increment in father’s occupational prestige, maternal IQ, and HOME score, respectively. Conclusions These results demonstrate that socioeconomic position, maternal IQ, and the home environment are independently and positively predictive of children’s cognitive development. These findings provide additional rationale for implementing social policies that reduce socioeconomic inequalities.

  • socioeconomic position maternal iq home environment and cognitive development
    The Journal of Pediatrics, 2007
    Co-Authors: Shilu Tong, Peter A Baghurst, Graham V Vimpani, Anthony J Mcmichael
    Abstract:

    OBJECTIVE: To assess whether socioeconomic position, maternal intelligence (IQ), and the home environment are inter-related to cognitive development in Childhood. Study DESIGN: Prospective cohort Study (n = 723) with cognitive tests at ages 2, 4, 7, and 11 to 13 years. RESULTS: There were statistically significant positive associations of father's occupational prestige, Home Observation for Measurement of Environment (HOME) score, and maternal IQ with cognitive performance in Childhood. After adjustment for confounding factors, there was an increase in cognitive development by 0.8 to 2.0, 2.9 to 4.8, and 4.2 to 9.0 points for a 10-unit increment in father's occupational prestige, maternal IQ, and HOME score, respectively. CONCLUSIONS: These results demonstrate that socioeconomic position, maternal IQ, and the home environment are independently and positively predictive of children's cognitive development. These findings provide additional rationale for implementing social policies that reduce socioeconomic inequalities.

John A Shepherd - One of the best experts on this subject based on the ideXlab platform.

  • Pediatric Reference Ranges for Ultradistal Radius Bone Density: Results from the Bone Mineral Density in Childhood Study.
    The Journal of Clinical Endocrinology and Metabolism, 2020
    Co-Authors: Joseph M. Kindler, Heidi J Kalkwarf, Vicente Gilsanz, Joan M Lappe, Sharon E Oberfield, Karen K Winer, John A Shepherd, Andrea Kelly, Babette S Zemel
    Abstract:

    Context The ultradistal (UD) radius is rich in trabecular bone and is easily measured by dual energy X-ray absorptiometry (DXA). UD radius areal bone mineral density (aBMD) may help identify trabecular bone deficits, but reference data are needed for research and clinical interpretation of this measure. Objective We developed age-, sex-, and population ancestry-specific reference ranges for UD radius aBMD assessed by DXA and calculated Z-scores. We examined tracking of UD radius aBMD Z-scores over 6 years and determined associations between UD radius aBMD Z-scores and other bone measures by DXA and peripheral quantitative computed tomography (pQCT). Design Multicenter longitudinal Study. Participants 2014 (922 males, 22% African American) children ages 5-19 years at enrollment who participated in the Bone Mineral Density in Childhood Study. Main outcome measure UD radius aBMD. Results UD radius aBMD increased non-linearly with age (p Conclusion UD radius aBMD Z-scores strongly associated with distal radius trabecular bone density, with marginal confounding by stature. These reference data may provide a valuable resource for bone health assessment in children.

  • revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non black children results of the bone mineral density in Childhood Study
    The Journal of Clinical Endocrinology and Metabolism, 2011
    Co-Authors: Babette S Zemel, Heidi J Kalkwarf, Vicente Gilsanz, Joan M Lappe, Sharon E Oberfield, Margaret M Frederick, John A Shepherd, Xangke Huang, Ming Lu, Soroosh Mahboubi
    Abstract:

    Context: Deficits in bone acquisition during growth may increase fracture risk. Assessment of bone health during Childhood requires appropriate reference values relative to age, sex, and population ancestry to identify bone deficits. Objective: The objective of this Study was to provide revised and extended reference curves for bone mineral content (BMC) and areal bone mineral density (aBMD) in children. Design: The Bone Mineral Density in Childhood Study was a multicenter longitudinal Study with annual assessments for up to 7 yr. Setting: The Study was conducted at five clinical centers in the United States. Participants: Two thousand fourteen healthy children (992 males, 22% African-Americans) aged 5–23 yr participated in the Study. Intervention: There were no interventions. Main Outcome Measures: Reference percentiles for BMC and aBMD of the total body, lumbar spine, hip, and forearm were obtained using dual-energy x-ray absorptiometry for Black and non-Black children. Adjustment factors for height sta...

  • height adjustment in assessing dual energy x ray absorptiometry measurements of bone mass and density in children
    The Journal of Clinical Endocrinology and Metabolism, 2010
    Co-Authors: Babette S Zemel, Vicente Gilsanz, Joan M Lappe, Sharon E Oberfield, Soroosh Mahboubi, John A Shepherd, Andrea Kelly, Mary B Leonard, Thomas N Hangartner, Margaret M Frederick
    Abstract:

    Context: In children, bone mineral content (BMC) and bone mineral density (BMD) measurements by dual-energy x-ray absorptiometry (DXA) are affected by height status. No consensus exists on how to adjust BMC or BMD (BMC/BMD) measurements for short or tall stature. Objective: The aim of this Study was to compare various methods to adjust BMC/BMD for height in healthy children. Design: Data from the Bone Mineral Density in Childhood Study (BMDCS) were used to develop adjustment methods that were validated using an independent cross-sectional sample of healthy children from the Reference Data Project (RDP). Setting: We conducted the Study in five clinical centers in the United States. Participants: We included 1546 BMDCS and 650 RDP participants (7 to 17 yr of age, 50% female). Intervention: No interventions were used. Main Outcome Measures: We measured spine and whole body (WB) BMC and BMD Z-scores for age (BMC/BMDage), height age (BMC/BMDheight age), height (BMCheight), bone mineral apparent density (BMADag...

  • the bone mineral density in Childhood Study bone mineral content and density according to age sex and race
    The Journal of Clinical Endocrinology and Metabolism, 2007
    Co-Authors: Heidi J Kalkwarf, Babette S Zemel, Vicente Gilsanz, Joan M Lappe, Mary Horlick, Sharon E Oberfield, Soroosh Mahboubi, Margaret M Frederick, Karen K Winer, John A Shepherd
    Abstract:

    Context: Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits. Objective: Our objective was to establish reference curves for bone mineral content (BMC) and density (BMD) in children. Design and Setting: The Bone Mineral Density in Childhood Study is an ongoing longitudinal Study in which measurements are obtained annually at five clinical centers in the United States. Participants: Participants included 1554 healthy children (761 male, 793 female), ages 6–16 yr, of all ethnicities. Main Outcome Measures: Scans of the whole body, lumbar spine, hip, and forearm were obtained using dual-energy x-ray absorptiometry. Percentile curves based on three annual measurements were generated using the LMS statistical procedure. Results: BMC of the whole body and lumbar spine and BMD of the whole body, lumbar spine, total hip, femoral n...

Soroosh Mahboubi - One of the best experts on this subject based on the ideXlab platform.

  • revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non black children results of the bone mineral density in Childhood Study
    The Journal of Clinical Endocrinology and Metabolism, 2011
    Co-Authors: Babette S Zemel, Heidi J Kalkwarf, Vicente Gilsanz, Joan M Lappe, Sharon E Oberfield, Margaret M Frederick, John A Shepherd, Xangke Huang, Ming Lu, Soroosh Mahboubi
    Abstract:

    Context: Deficits in bone acquisition during growth may increase fracture risk. Assessment of bone health during Childhood requires appropriate reference values relative to age, sex, and population ancestry to identify bone deficits. Objective: The objective of this Study was to provide revised and extended reference curves for bone mineral content (BMC) and areal bone mineral density (aBMD) in children. Design: The Bone Mineral Density in Childhood Study was a multicenter longitudinal Study with annual assessments for up to 7 yr. Setting: The Study was conducted at five clinical centers in the United States. Participants: Two thousand fourteen healthy children (992 males, 22% African-Americans) aged 5–23 yr participated in the Study. Intervention: There were no interventions. Main Outcome Measures: Reference percentiles for BMC and aBMD of the total body, lumbar spine, hip, and forearm were obtained using dual-energy x-ray absorptiometry for Black and non-Black children. Adjustment factors for height sta...

  • height adjustment in assessing dual energy x ray absorptiometry measurements of bone mass and density in children
    The Journal of Clinical Endocrinology and Metabolism, 2010
    Co-Authors: Babette S Zemel, Vicente Gilsanz, Joan M Lappe, Sharon E Oberfield, Soroosh Mahboubi, John A Shepherd, Andrea Kelly, Mary B Leonard, Thomas N Hangartner, Margaret M Frederick
    Abstract:

    Context: In children, bone mineral content (BMC) and bone mineral density (BMD) measurements by dual-energy x-ray absorptiometry (DXA) are affected by height status. No consensus exists on how to adjust BMC or BMD (BMC/BMD) measurements for short or tall stature. Objective: The aim of this Study was to compare various methods to adjust BMC/BMD for height in healthy children. Design: Data from the Bone Mineral Density in Childhood Study (BMDCS) were used to develop adjustment methods that were validated using an independent cross-sectional sample of healthy children from the Reference Data Project (RDP). Setting: We conducted the Study in five clinical centers in the United States. Participants: We included 1546 BMDCS and 650 RDP participants (7 to 17 yr of age, 50% female). Intervention: No interventions were used. Main Outcome Measures: We measured spine and whole body (WB) BMC and BMD Z-scores for age (BMC/BMDage), height age (BMC/BMDheight age), height (BMCheight), bone mineral apparent density (BMADag...

  • the bone mineral density in Childhood Study bone mineral content and density according to age sex and race
    The Journal of Clinical Endocrinology and Metabolism, 2007
    Co-Authors: Heidi J Kalkwarf, Babette S Zemel, Vicente Gilsanz, Joan M Lappe, Mary Horlick, Sharon E Oberfield, Soroosh Mahboubi, Margaret M Frederick, Karen K Winer, John A Shepherd
    Abstract:

    Context: Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits. Objective: Our objective was to establish reference curves for bone mineral content (BMC) and density (BMD) in children. Design and Setting: The Bone Mineral Density in Childhood Study is an ongoing longitudinal Study in which measurements are obtained annually at five clinical centers in the United States. Participants: Participants included 1554 healthy children (761 male, 793 female), ages 6–16 yr, of all ethnicities. Main Outcome Measures: Scans of the whole body, lumbar spine, hip, and forearm were obtained using dual-energy x-ray absorptiometry. Percentile curves based on three annual measurements were generated using the LMS statistical procedure. Results: BMC of the whole body and lumbar spine and BMD of the whole body, lumbar spine, total hip, femoral n...

Babette S Zemel - One of the best experts on this subject based on the ideXlab platform.

  • Pediatric Reference Ranges for Ultradistal Radius Bone Density: Results from the Bone Mineral Density in Childhood Study.
    The Journal of Clinical Endocrinology and Metabolism, 2020
    Co-Authors: Joseph M. Kindler, Heidi J Kalkwarf, Vicente Gilsanz, Joan M Lappe, Sharon E Oberfield, Karen K Winer, John A Shepherd, Andrea Kelly, Babette S Zemel
    Abstract:

    Context The ultradistal (UD) radius is rich in trabecular bone and is easily measured by dual energy X-ray absorptiometry (DXA). UD radius areal bone mineral density (aBMD) may help identify trabecular bone deficits, but reference data are needed for research and clinical interpretation of this measure. Objective We developed age-, sex-, and population ancestry-specific reference ranges for UD radius aBMD assessed by DXA and calculated Z-scores. We examined tracking of UD radius aBMD Z-scores over 6 years and determined associations between UD radius aBMD Z-scores and other bone measures by DXA and peripheral quantitative computed tomography (pQCT). Design Multicenter longitudinal Study. Participants 2014 (922 males, 22% African American) children ages 5-19 years at enrollment who participated in the Bone Mineral Density in Childhood Study. Main outcome measure UD radius aBMD. Results UD radius aBMD increased non-linearly with age (p Conclusion UD radius aBMD Z-scores strongly associated with distal radius trabecular bone density, with marginal confounding by stature. These reference data may provide a valuable resource for bone health assessment in children.

  • revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non black children results of the bone mineral density in Childhood Study
    The Journal of Clinical Endocrinology and Metabolism, 2011
    Co-Authors: Babette S Zemel, Heidi J Kalkwarf, Vicente Gilsanz, Joan M Lappe, Sharon E Oberfield, Margaret M Frederick, John A Shepherd, Xangke Huang, Ming Lu, Soroosh Mahboubi
    Abstract:

    Context: Deficits in bone acquisition during growth may increase fracture risk. Assessment of bone health during Childhood requires appropriate reference values relative to age, sex, and population ancestry to identify bone deficits. Objective: The objective of this Study was to provide revised and extended reference curves for bone mineral content (BMC) and areal bone mineral density (aBMD) in children. Design: The Bone Mineral Density in Childhood Study was a multicenter longitudinal Study with annual assessments for up to 7 yr. Setting: The Study was conducted at five clinical centers in the United States. Participants: Two thousand fourteen healthy children (992 males, 22% African-Americans) aged 5–23 yr participated in the Study. Intervention: There were no interventions. Main Outcome Measures: Reference percentiles for BMC and aBMD of the total body, lumbar spine, hip, and forearm were obtained using dual-energy x-ray absorptiometry for Black and non-Black children. Adjustment factors for height sta...

  • height adjustment in assessing dual energy x ray absorptiometry measurements of bone mass and density in children
    The Journal of Clinical Endocrinology and Metabolism, 2010
    Co-Authors: Babette S Zemel, Vicente Gilsanz, Joan M Lappe, Sharon E Oberfield, Soroosh Mahboubi, John A Shepherd, Andrea Kelly, Mary B Leonard, Thomas N Hangartner, Margaret M Frederick
    Abstract:

    Context: In children, bone mineral content (BMC) and bone mineral density (BMD) measurements by dual-energy x-ray absorptiometry (DXA) are affected by height status. No consensus exists on how to adjust BMC or BMD (BMC/BMD) measurements for short or tall stature. Objective: The aim of this Study was to compare various methods to adjust BMC/BMD for height in healthy children. Design: Data from the Bone Mineral Density in Childhood Study (BMDCS) were used to develop adjustment methods that were validated using an independent cross-sectional sample of healthy children from the Reference Data Project (RDP). Setting: We conducted the Study in five clinical centers in the United States. Participants: We included 1546 BMDCS and 650 RDP participants (7 to 17 yr of age, 50% female). Intervention: No interventions were used. Main Outcome Measures: We measured spine and whole body (WB) BMC and BMD Z-scores for age (BMC/BMDage), height age (BMC/BMDheight age), height (BMCheight), bone mineral apparent density (BMADag...

  • the bone mineral density in Childhood Study bone mineral content and density according to age sex and race
    The Journal of Clinical Endocrinology and Metabolism, 2007
    Co-Authors: Heidi J Kalkwarf, Babette S Zemel, Vicente Gilsanz, Joan M Lappe, Mary Horlick, Sharon E Oberfield, Soroosh Mahboubi, Margaret M Frederick, Karen K Winer, John A Shepherd
    Abstract:

    Context: Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits. Objective: Our objective was to establish reference curves for bone mineral content (BMC) and density (BMD) in children. Design and Setting: The Bone Mineral Density in Childhood Study is an ongoing longitudinal Study in which measurements are obtained annually at five clinical centers in the United States. Participants: Participants included 1554 healthy children (761 male, 793 female), ages 6–16 yr, of all ethnicities. Main Outcome Measures: Scans of the whole body, lumbar spine, hip, and forearm were obtained using dual-energy x-ray absorptiometry. Percentile curves based on three annual measurements were generated using the LMS statistical procedure. Results: BMC of the whole body and lumbar spine and BMD of the whole body, lumbar spine, total hip, femoral n...