The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Fernando Saldias P - One of the best experts on this subject based on the ideXlab platform.
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hierbas medicinales y graves efectos adversos angioedema de uvula causado por uso de ecballium elaterium
Revista Medica De Chile, 2002Co-Authors: Gianella Caiozzi A, Daniel Cabrera T, Jose Miguel Mardonez U, Fernando Saldias PAbstract:Herbal medicine is a growing alternative for established medicine. Many plants and herbs are currently in use for a myriad of diseases and symptoms. However, there are many reports in the literature of life-threatening adverse effects of these drugs. We report a 39 years old male, that consulted for pain in the nostrils and severe nasal obstruction, that appeared two hours after instilling Ecballium elaterirum in the nostrils. On physical examination, uvular edema was observed. The patient was successfully managed with intravenous betametasone and Chlorphenamine.
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hierbas medicinales y graves efectos adversos angioedema de uvula causado por uso de ecballium elaterium
Revista Medica De Chile, 2002Co-Authors: Gianella Caiozzi A, Daniel Cabrera T, Jose Miguel Mardonez U, Fernando Saldias PAbstract:Herbal medicine is a growing alternative for established medicine. Many plants and herbs are currently in use for a myriad of diseases and symptoms. However, there are many reports in the literature of life-threatening adverse effects of these drugs. We report a 39 years old male, that consulted for pain in the nostrils and severe nasal obstruction, that appeared two hours after instilling Ecballium elaterirum in the nostrils. On physical examination, uvular edema was observed. The patient was successfully managed with intravenous betametasone and Chlorphenamine (Rev Med Chile 2002; 130: 1407-10
Luis Felipe Carissimi Schmidt - One of the best experts on this subject based on the ideXlab platform.
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symptomatic treatment of the common cold with a fixed dose combination of paracetamol Chlorphenamine and phenylephrine a randomized placebo controlled trial
BMC Infectious Diseases, 2013Co-Authors: Paulo Dornelles Picon, Marisa Da Costa, Rafael Da Veiga Chaves Picon, Lucia Costa Cabral Fendt, Mauricio Leichter Suksteris, Indara Carmanim Saccilotto, Alicia Dorneles Dornelles, Luis Felipe Carissimi SchmidtAbstract:The common cold and other viral airway infections are highly prevalent in the population, and their treatment often requires the use of medications for symptomatic relief. Paracetamol is as an analgesic and antipyretic; Chlorphenamine is an antihistamine; and phenylephrine, a vasoconstrictor and decongestant. This randomized, double-blind, placebo-controlled trial sought to evaluate the efficacy and safety of a fixed-dose combination of paracetamol, Chlorphenamine and phenylephrine in the symptomatic treatment of the common cold and flu-like syndrome in adults. This study enrolled 146 individuals aged 18 to 60 years who had moderate to severe flu-like syndrome or common cold. After clinical examination and laboratory tests, individuals were randomly assigned to receive the fixed-dose combination (73) or placebo (73), five capsules per day for 48 to 72 hours. The primary efficacy endpoint was the sum of the scores of 10 symptoms on a four-point Likert-type scale. To evaluate treatment safety, the occurrence of adverse events was also measured. Mean age was 33.5 (±9.5) years in the placebo group and 33.8 (±11.5) in the treatment group. There were 55 women and 18 men in the placebo group, and 46 women and 27 men in the treatment group. Comparison of overall symptom scores in the two groups revealed a significantly greater reduction in the treatment group than in the placebo group (p = 0.015). Analysis at the first 13 dose intervals (± 66 h of treatment) showed a greater reduction of symptom scores in the treatment group than in the placebo group (p < 0.05). The number and distribution of adverse events were similar in both groups. A fixed-dose combination of paracetamol, Chlorphenamine and phenylephrine was safe and more effective than placebo in the symptomatic treatment of the common cold or flu-like syndrome in adults. NCT01389518
Shenyang Tong - One of the best experts on this subject based on the ideXlab platform.
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the specificity of a Chlorphenamine imprinted polymer and its application
Talanta, 2001Co-Authors: Wen Chen, Feng Liu, Xuemin Zhang, Shenyang TongAbstract:A Chlorphenamine-imprinted polymer was prepared in this study. Chromatographic analysis showed that the retentivity and selectivity of the imprinted polymer were greatly strengthened through molecular imprinting. As a consequence, Chlorphenamine could be easily separated from diphenhydramine. Ionic interaction was proved to be the main power for the imprinted polymer to bind Chlorphenamine. The strong extraction ability of the imprinted polymer for Chlorphenamine in aqueous solution was evaluated further. It was shown that Chlorphenamine, as low as 0.02 mumol l(-1), could be concentrated by 50 times with a recovery of more than 90% at pH 5. This study gave the potential of using the imprinted polymer for solid-phase extraction of practical samples.
Sy Tong - One of the best experts on this subject based on the ideXlab platform.
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The specificity of a Chlorphenamine-imprinted polymer and its application
talanta, 2001Co-Authors: Chen W, Liu F, Xm Zhang, Sy TongAbstract:A Chlorphenamine-imprinted polymer was prepared in this study. Chromatographic analysis showed that the retentivity and selectivity of the imprinted polymer were greatly strengthened through molecular imprinting. As a consequence, Chlorphenamine could be easily separated from diphenhydramine. Ionic interaction was proved to be the main power for the imprinted polymer to bind Chlorphenamine. The strong extraction ability of the imprinted polymer for Chlorphenamine in aqueous solution was evaluated further. It was shown that Chlorphenamine, as low as 0.02 mu mol l(-1), could be concentrated by 50 times with a recovery of more than 90% at pH 5. This study gave the potential of using the imprinted polymer for solid-phase extraction of practical samples. (C) 2001 Elsevier Science B.V. All rights reserved.Chemistry, AnalyticalSCI(E)EIPubMed0ARTICLE129-345
Gianella Caiozzi A - One of the best experts on this subject based on the ideXlab platform.
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hierbas medicinales y graves efectos adversos angioedema de uvula causado por uso de ecballium elaterium
Revista Medica De Chile, 2002Co-Authors: Gianella Caiozzi A, Daniel Cabrera T, Jose Miguel Mardonez U, Fernando Saldias PAbstract:Herbal medicine is a growing alternative for established medicine. Many plants and herbs are currently in use for a myriad of diseases and symptoms. However, there are many reports in the literature of life-threatening adverse effects of these drugs. We report a 39 years old male, that consulted for pain in the nostrils and severe nasal obstruction, that appeared two hours after instilling Ecballium elaterirum in the nostrils. On physical examination, uvular edema was observed. The patient was successfully managed with intravenous betametasone and Chlorphenamine.
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hierbas medicinales y graves efectos adversos angioedema de uvula causado por uso de ecballium elaterium
Revista Medica De Chile, 2002Co-Authors: Gianella Caiozzi A, Daniel Cabrera T, Jose Miguel Mardonez U, Fernando Saldias PAbstract:Herbal medicine is a growing alternative for established medicine. Many plants and herbs are currently in use for a myriad of diseases and symptoms. However, there are many reports in the literature of life-threatening adverse effects of these drugs. We report a 39 years old male, that consulted for pain in the nostrils and severe nasal obstruction, that appeared two hours after instilling Ecballium elaterirum in the nostrils. On physical examination, uvular edema was observed. The patient was successfully managed with intravenous betametasone and Chlorphenamine (Rev Med Chile 2002; 130: 1407-10