The Experts below are selected from a list of 228 Experts worldwide ranked by ideXlab platform
Peter A Nolte - One of the best experts on this subject based on the ideXlab platform.
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there is no difference in postoperative pain function and complications in patients with Chondrocalcinosis in the outcome of total knee arthroplasty for end stage osteoarthritis
Knee Surgery Sports Traumatology Arthroscopy, 2020Co-Authors: Jore H. Willems, Rachid Rassir, Inger N Sierevelt, Peter A NolteAbstract:Purpose Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative Chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if Chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without Chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis.
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There is no difference in postoperative pain, function and complications in patients with Chondrocalcinosis in the outcome of total knee arthroplasty for end-stage osteoarthritis
Knee Surgery Sports Traumatology Arthroscopy, 2019Co-Authors: Jore H. Willems, Rachid Rassir, Inger N Sierevelt, Peter A NolteAbstract:Purpose Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative Chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if Chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without Chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis. Methods In this retrospective cohort study performed in 2017, 408 knees in 392 patients (16 bilateral total knee arthroplasties) were included. None of the patients received additional synovectomy. PROMs were evaluated after 1 year ( n = 294) and 5 years ( n = 308). The follow-up for clinical data was 5 years ( n = 408). The range of final follow-up was 57–84 months. All preoperative radiographs were scored for Chondrocalcinosis and Oxford Knee Score, Knee Society Score and Algofunctional Index were used to assess outcome. All clinical records were screened for postoperative complications (excessive wound discharge, infection, loosening, PAO, stiffness), arthritis after surgery and reoperation or revision for any reason. Results Sixty-three knees (15.4%) showed signs of Chondrocalcinosis. Male gender, higher age and lower BMI were risk factors for Chondrocalcinosis. No difference was found in Oxford Knee Score, Knee Society Score and Algofunctional Index, nor in postoperative complications, postoperative signs of acute arthritis and revision rate. Conclusion Patients with and without Chondrocalcinosis have the same outcome after total knee arthroplasty related to pain, functionality, complications, arthritis and revision after surgery for end-stage osteoarthritis. Chondrocalcinosis is not a contraindication for total knee arthroplasty and additional synovectomy is unnecessary. Level of evidence III.
Jore H. Willems - One of the best experts on this subject based on the ideXlab platform.
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there is no difference in postoperative pain function and complications in patients with Chondrocalcinosis in the outcome of total knee arthroplasty for end stage osteoarthritis
Knee Surgery Sports Traumatology Arthroscopy, 2020Co-Authors: Jore H. Willems, Rachid Rassir, Inger N Sierevelt, Peter A NolteAbstract:Purpose Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative Chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if Chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without Chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis.
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There is no difference in postoperative pain, function and complications in patients with Chondrocalcinosis in the outcome of total knee arthroplasty for end-stage osteoarthritis
Knee Surgery Sports Traumatology Arthroscopy, 2019Co-Authors: Jore H. Willems, Rachid Rassir, Inger N Sierevelt, Peter A NolteAbstract:Purpose Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative Chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if Chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without Chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis. Methods In this retrospective cohort study performed in 2017, 408 knees in 392 patients (16 bilateral total knee arthroplasties) were included. None of the patients received additional synovectomy. PROMs were evaluated after 1 year ( n = 294) and 5 years ( n = 308). The follow-up for clinical data was 5 years ( n = 408). The range of final follow-up was 57–84 months. All preoperative radiographs were scored for Chondrocalcinosis and Oxford Knee Score, Knee Society Score and Algofunctional Index were used to assess outcome. All clinical records were screened for postoperative complications (excessive wound discharge, infection, loosening, PAO, stiffness), arthritis after surgery and reoperation or revision for any reason. Results Sixty-three knees (15.4%) showed signs of Chondrocalcinosis. Male gender, higher age and lower BMI were risk factors for Chondrocalcinosis. No difference was found in Oxford Knee Score, Knee Society Score and Algofunctional Index, nor in postoperative complications, postoperative signs of acute arthritis and revision rate. Conclusion Patients with and without Chondrocalcinosis have the same outcome after total knee arthroplasty related to pain, functionality, complications, arthritis and revision after surgery for end-stage osteoarthritis. Chondrocalcinosis is not a contraindication for total knee arthroplasty and additional synovectomy is unnecessary. Level of evidence III.
Rachid Rassir - One of the best experts on this subject based on the ideXlab platform.
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there is no difference in postoperative pain function and complications in patients with Chondrocalcinosis in the outcome of total knee arthroplasty for end stage osteoarthritis
Knee Surgery Sports Traumatology Arthroscopy, 2020Co-Authors: Jore H. Willems, Rachid Rassir, Inger N Sierevelt, Peter A NolteAbstract:Purpose Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative Chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if Chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without Chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis.
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There is no difference in postoperative pain, function and complications in patients with Chondrocalcinosis in the outcome of total knee arthroplasty for end-stage osteoarthritis
Knee Surgery Sports Traumatology Arthroscopy, 2019Co-Authors: Jore H. Willems, Rachid Rassir, Inger N Sierevelt, Peter A NolteAbstract:Purpose Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative Chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if Chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without Chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis. Methods In this retrospective cohort study performed in 2017, 408 knees in 392 patients (16 bilateral total knee arthroplasties) were included. None of the patients received additional synovectomy. PROMs were evaluated after 1 year ( n = 294) and 5 years ( n = 308). The follow-up for clinical data was 5 years ( n = 408). The range of final follow-up was 57–84 months. All preoperative radiographs were scored for Chondrocalcinosis and Oxford Knee Score, Knee Society Score and Algofunctional Index were used to assess outcome. All clinical records were screened for postoperative complications (excessive wound discharge, infection, loosening, PAO, stiffness), arthritis after surgery and reoperation or revision for any reason. Results Sixty-three knees (15.4%) showed signs of Chondrocalcinosis. Male gender, higher age and lower BMI were risk factors for Chondrocalcinosis. No difference was found in Oxford Knee Score, Knee Society Score and Algofunctional Index, nor in postoperative complications, postoperative signs of acute arthritis and revision rate. Conclusion Patients with and without Chondrocalcinosis have the same outcome after total knee arthroplasty related to pain, functionality, complications, arthritis and revision after surgery for end-stage osteoarthritis. Chondrocalcinosis is not a contraindication for total knee arthroplasty and additional synovectomy is unnecessary. Level of evidence III.
Inger N Sierevelt - One of the best experts on this subject based on the ideXlab platform.
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there is no difference in postoperative pain function and complications in patients with Chondrocalcinosis in the outcome of total knee arthroplasty for end stage osteoarthritis
Knee Surgery Sports Traumatology Arthroscopy, 2020Co-Authors: Jore H. Willems, Rachid Rassir, Inger N Sierevelt, Peter A NolteAbstract:Purpose Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative Chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if Chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without Chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis.
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There is no difference in postoperative pain, function and complications in patients with Chondrocalcinosis in the outcome of total knee arthroplasty for end-stage osteoarthritis
Knee Surgery Sports Traumatology Arthroscopy, 2019Co-Authors: Jore H. Willems, Rachid Rassir, Inger N Sierevelt, Peter A NolteAbstract:Purpose Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative Chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if Chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without Chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis. Methods In this retrospective cohort study performed in 2017, 408 knees in 392 patients (16 bilateral total knee arthroplasties) were included. None of the patients received additional synovectomy. PROMs were evaluated after 1 year ( n = 294) and 5 years ( n = 308). The follow-up for clinical data was 5 years ( n = 408). The range of final follow-up was 57–84 months. All preoperative radiographs were scored for Chondrocalcinosis and Oxford Knee Score, Knee Society Score and Algofunctional Index were used to assess outcome. All clinical records were screened for postoperative complications (excessive wound discharge, infection, loosening, PAO, stiffness), arthritis after surgery and reoperation or revision for any reason. Results Sixty-three knees (15.4%) showed signs of Chondrocalcinosis. Male gender, higher age and lower BMI were risk factors for Chondrocalcinosis. No difference was found in Oxford Knee Score, Knee Society Score and Algofunctional Index, nor in postoperative complications, postoperative signs of acute arthritis and revision rate. Conclusion Patients with and without Chondrocalcinosis have the same outcome after total knee arthroplasty related to pain, functionality, complications, arthritis and revision after surgery for end-stage osteoarthritis. Chondrocalcinosis is not a contraindication for total knee arthroplasty and additional synovectomy is unnecessary. Level of evidence III.
Robert Terkeltaub - One of the best experts on this subject based on the ideXlab platform.
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dose response relationship between lower serum magnesium level and higher prevalence of knee Chondrocalcinosis
Arthritis Research & Therapy, 2017Co-Authors: Chao Zeng, Robert Terkeltaub, Tuo Yang, Hyon K Choi, Yilun Wang, David J Hunter, Yuqing Zhang, Hui Li, Liangjun LiAbstract:The aim was to assess serum magnesium levels in relation to prevalence of knee Chondrocalcinosis in two population-based Chinese studies. Data included in this analysis consisted of two population-based cross-sectional studies, i.e., the Xiangya Hospital Health Management Center Study and the Xiangya Osteoarthritis (XO) Study I. A bilateral knee anteroposterior radiograph was obtained from each subject. Radiographic knee Chondrocalcinosis was present if there was definite linear cartilage calcification. Serum magnesium concentration was measured using the chemiluminescence method. We examined the relation of serum magnesium levels to prevalence of knee Chondrocalcinosis using generalized estimating equations. The prevalence of knee Chondrocalcinosis was 1.4% in the Xiangya Hospital Health Management Center Study (n = 12,631). Compared with the lowest tertile, the age, sex and body mass index (BMI)-adjusted odds ratios (ORs) of Chondrocalcinosis were 0.59 (95% CI 0.40–0.87) and 0.49 (95% CI 0.33–0.72) in the second and the third tertiles of serum magnesium, respectively (P for trend <0.001). The prevalence of knee Chondrocalcinosis in the XO Study I (n = 1316) was 4.1%. The age, sex and BMI-adjusted ORs of Chondrocalcinosis were 0.67 (95% CI 0.34–1.30) in the second and 0.45 (95% CI 0.21–0.94) in the third tertile of serum magnesium when compared with the lowest tertile (P for trend = 0.030). Similar results were observed in men and women in both studies. Adjusting for additional potential confounders did not change the results materially. Subjects with lower levels of serum magnesium, even within the normal range, had higher prevalence of knee Chondrocalcinosis in a dose-response relationship manner, suggesting that magnesium may have a preventive or therapeutic potential for knee Chondrocalcinosis.
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Additional file 2: Table S1. of Dose-response relationship between lower serum magnesium level and higher prevalence of knee Chondrocalcinosis
2017Co-Authors: Chao Zeng, Robert Terkeltaub, Tuo Yang, Yilun Wang, Jie Wei, Hyon Choi, Dong-xing Xie, David Hunter, Yuqing ZhangAbstract:Association between serum Mg and knee Chondrocalcinosis in the Xiangya Hospital Health Management Center Study (n = 12,631). Table S2. Association between serum Mg and knee Chondrocalcinosis in the XO Study I (n = 1316). Figure S1. Association between serum Mg and OR of CC analyzed by spline regression (3 knots, 0,7 as reference) in the Xiangya Hospital Health Management Center Study (P = 0.049). Mg, magnesium; CC, Chondrocalcinosis; OR, odds ratio; CI, confidence interval. Figure S2. Association between serum Mg and OR of CC analyzed by spline regression (3 knots, 0,7 as reference) in the XO Study I (P = 0.060). Mg, magnesium; CC, Chondrocalcinosis; OR, odds ratio; CI, confidence interval. (DOCX 1720 kb
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Dose-response relationship between lower serum magnesium level and higher prevalence of knee Chondrocalcinosis
BMC, 2017Co-Authors: Chao Zeng, Robert Terkeltaub, Tuo Yang, Hyon K Choi, Yilun Wang, David J Hunter, Jie Wei, Dong-xing Xie, Yuqing ZhangAbstract:Abstract Background The aim was to assess serum magnesium levels in relation to prevalence of knee Chondrocalcinosis in two population-based Chinese studies. Methods Data included in this analysis consisted of two population-based cross-sectional studies, i.e., the Xiangya Hospital Health Management Center Study and the Xiangya Osteoarthritis (XO) Study I. A bilateral knee anteroposterior radiograph was obtained from each subject. Radiographic knee Chondrocalcinosis was present if there was definite linear cartilage calcification. Serum magnesium concentration was measured using the chemiluminescence method. We examined the relation of serum magnesium levels to prevalence of knee Chondrocalcinosis using generalized estimating equations. Results The prevalence of knee Chondrocalcinosis was 1.4% in the Xiangya Hospital Health Management Center Study (n = 12,631). Compared with the lowest tertile, the age, sex and body mass index (BMI)-adjusted odds ratios (ORs) of Chondrocalcinosis were 0.59 (95% CI 0.40–0.87) and 0.49 (95% CI 0.33–0.72) in the second and the third tertiles of serum magnesium, respectively (P for trend
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lower prevalence of Chondrocalcinosis in chinese subjects in beijing than in white subjects in the united states the beijing osteoarthritis study
Arthritis & Rheumatism, 2006Co-Authors: Yuqing Zhang, Robert Terkeltaub, Jingbo Niu, Michael C Nevitt, Tuhina Neogi, Piaran Aliabadi, David T. FelsonAbstract:Objective Chondrocalcinosis, which can promote joint inflammation and cartilage degeneration, is highly prevalent in elderly white subjects. Data on its prevalence are scarce in other ethnic populations. This study was undertaken to compare the prevalence of Chondrocalcinosis in Chinese subjects with that in white subjects. Methods We recruited a random sample of Beijing residents ages ≥60 years. Participants underwent standard weight-bearing anteroposterior knee radiography and posteroanterior hand radiography using the protocols developed in the Framingham Osteoarthritis Study. Radiographic Chondrocalcinosis was defined as present in a knee or wrist when there was evidence of definite linear cartilage calcification. We compared the prevalence of Chondrocalcinosis in Chinese subjects with that in white subjects using age-standardized prevalence ratios. We used identical methods to collect samples of tap water from 2 cities and measured their levels of calcium, magnesium, and phosphate in the same laboratory. Results Chinese subjects had a much lower prevalence of knee Chondrocalcinosis (1.8% in men, 2.7% in women) than did white subjects (6.2% in men, 7.7% in women), with the age-standardized prevalence ratio being 0.34 (95% confidence interval [95% CI] 0.20–0.54) and 0.43 (95% CI 0.31–0.59) in men and women, respectively. Wrist Chondrocalcinosis was rare in elderly Chinese subjects (prevalence 0.3% in men and 1.0% in women), with the age-standardized prevalence ratio being 0.06 (95% CI 0.01–0.18) in Chinese men and 0.18 (95% CI 0.10–0.30) in Chinese women. Calcium levels in the tap water in Beijing were 15-fold higher than in Framingham, whereas no difference was found in magnesium and phosphate levels. Conclusion Knee Chondrocalcinosis and wrist Chondrocalcinosis are far less common in Chinese subjects in Beijing than in US white subjects in Framingham, Massachusetts. Given the current lack of understanding of the etiology of Chondrocalcinosis, further epidemiologic studies of the impact of genetic and environmental factors on occurrence of Chondrocalcinosis are indicated.
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lack of association between Chondrocalcinosis and increased risk of cartilage loss in knees with osteoarthritis results of two prospective longitudinal magnetic resonance imaging studies
Arthritis & Rheumatism, 2006Co-Authors: Tuhina Neogi, Robert Terkeltaub, Jingbo Niu, David J Hunter, Michael C Nevitt, Michael P Lavalley, Laura D Carbone, Hepei Chen, Tamara B Harris, K KwohAbstract:Objective To evaluate the relationship between Chondrocalcinosis and the progression of knee osteoarthritis (OA) using longitudinal magnetic resonance imaging (MRI) assessments. Methods Longitudinal knee MRIs were obtained in the Boston OA Knee Study (BOKS) and in the Health, Aging and Body Composition (Health ABC) Study. Chondrocalcinosis was determined as present or absent on baseline knee radiographs. Cartilage morphology was graded on paired longitudinal MRIs using the Whole-Organ Magnetic Resonance Imaging Score in 5 cartilage subregions of each of the medial and lateral tibiofemoral joints. Cartilage loss in a subregion was defined as an increase in the cartilage score of ≥1 (0–4 scale). The risk for change in the number of subregions with cartilage loss was assessed using Poisson regression, with generalized estimating equations to account for correlations. Analyses were adjusted for age, sex, body mass index, baseline cartilage score, and presence of damaged menisci. Results In BOKS, 23 of the 265 included knees (9%) had Chondrocalcinosis. In Health ABC, 373 knees were included, of which 69 knees (18.5%) had Chondrocalcinosis. In BOKS, knees with Chondrocalcinosis had a lower risk of cartilage loss compared with knees without Chondrocalcinosis (adjusted risk ratio [RR] 0.4, 95% confidence interval [95% CI] 0.2–0.7) (P = 0.002), and there was no difference in risk in Health ABC (adjusted RR 0.9, 95% CI 0.6–1.5) (P = 0.7). Stratification by intact versus damaged menisci produced similar results within each cohort. Conclusion In knees with OA, the presence of Chondrocalcinosis was not associated with increased cartilage loss. These findings do not support the hypothesis that Chondrocalcinosis worsens OA progression.