The Experts below are selected from a list of 519 Experts worldwide ranked by ideXlab platform
Emmett T Cunningham - One of the best experts on this subject based on the ideXlab platform.
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complex limbal Choristomas in linear nevus sebaceous syndrome
Ophthalmology, 1998Co-Authors: Jacque L Duncan, Mahin Golabi, Douglas R Fredrick, Creig S Hoyt, David G Hwang, Steven G Kramer, Edward L Howes, Emmett T CunninghamAbstract:Abstract Objective This study aimed to describe the clinical and histopathologic findings in four patients with complex limbal Choristomas associated with linear nevus sebaceous syndrome (LNSS), a rare disorder including nevus sebaceous, seizures, and mental retardation, and often accompanied by ocular anomalies. Design Small observational case series. Methods A retrospective review of the clinical and histopathologic records of four patients. Results Each of four patients had complex limbal Choristomas in the setting of clinical and histopathologic LNSS. The limbal Choristomas were multiple in three patients and bilateral in two patients. Most Choristomas involved the superotemporal limbus (6 of 10), although nasal (3 of 10) and inferior (1 of 10) limbal tumors also were present. Three patients had significant corneal astigmatism or involvement of the central cornea requiring surgical removal of their Choristomas, one accompanied by a lamellar keratoplasty and another accompanied by two consecutive penetrating keratoplasties. Each graft eventually vascularized, reducing vision. One patient's vision was limited by amblyopia and another by occipital cortical dysgenesis with visual impairment. Histopathologic examination of the excised Choristomas showed foci of lacrimal gland (3 of 4 patients), adipose tissue (3 of 4), neural tissue (1 of 4), cartilage (1 of 4), lymphoid follicles (1 of 4), skin adnexal tissue (1 of 4), and smooth muscle (1 of 4). Other associated ocular findings included an eyelid mass (1 of 4), colobomas of the eyelid (3 of 4), colobomas of the choroid and retina (2 of 4), nonparalytic strabismus (2 of 4), scleral ectasia (1 of 4), partial oculomotor palsy with ptosis and anisocoria (1 of 4), microphthalmia (1 of 4), and cortical visual impairment (1 of 4). Conclusions Complex limbal Choristomas, although rare, can occur in the setting of LNSS and can be associated with multiple ocular and systemic abnormalities. Visual prognosis appears poor in most cases despite aggressive management.
Fei Peng Lee - One of the best experts on this subject based on the ideXlab platform.
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cartilaginous Choristoma of the bony external auditory canal a study of 36 cases
Otolaryngology-Head and Neck Surgery, 2005Co-Authors: Fei Peng LeeAbstract:OBJECTIVE: The study goal is to present the clinical data of 36 cases of heterotopic cartilaginous mass in the bony external auditory canal and to clarify the terminology used to describe this clinical entity.STUDY DESIGN AND SETTING: We conducted a medical record review of 36 consecutive patients with lesions (26 of which were excised) seen at two Departments of Otolaryngology in Taiwan.RESULTS: Histopathological examination revealed that all 26 excised lesions were composed of mature hyaline cartilage, and on this basis, cartilaginous Choristoma was diagnosed.CONCLUSION: The presence of a heterotopic cartilaginous mass in the bony external ear canal is not as rare as it was once thought to be. The descriptive term “cartilaginous Choristoma” rather than “chondroma” may be more appropriate for these lesions.
Koji Kashima - One of the best experts on this subject based on the ideXlab platform.
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epidermal Choristoma arising on the midline gingiva as a congenital epulis a case report
Journal of Cranio-maxillofacial Surgery, 2012Co-Authors: Izumi Yoshioka, Kousuke Marutsuka, Kaori Igawa, Jyunko Nagata, Maho Yoshida, Takashi Baba, Takeshi Ichiki, Yudai Kondoh, Koichi Takamori, Koji KashimaAbstract:We report an extremely rare case of epidermal Choristoma in the midline of the maxillary gingiva. A 2-month-old Japanese boy presented with a polypoid mass in the midline of the maxillary gingiva. The initial clinical diagnosis was congenital epulis. Microscopic examination revealed a granular cell layer and melanin pigmentation within the basal cell layer. Furthermore, sebaceous glands and hair follicles were observed within the connective tissue. The histological diagnosis was therefore epidermal Choristoma, based on clinical microscopic observations.
Jacque L Duncan - One of the best experts on this subject based on the ideXlab platform.
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complex limbal Choristomas in linear nevus sebaceous syndrome
Ophthalmology, 1998Co-Authors: Jacque L Duncan, Mahin Golabi, Douglas R Fredrick, Creig S Hoyt, David G Hwang, Steven G Kramer, Edward L Howes, Emmett T CunninghamAbstract:Abstract Objective This study aimed to describe the clinical and histopathologic findings in four patients with complex limbal Choristomas associated with linear nevus sebaceous syndrome (LNSS), a rare disorder including nevus sebaceous, seizures, and mental retardation, and often accompanied by ocular anomalies. Design Small observational case series. Methods A retrospective review of the clinical and histopathologic records of four patients. Results Each of four patients had complex limbal Choristomas in the setting of clinical and histopathologic LNSS. The limbal Choristomas were multiple in three patients and bilateral in two patients. Most Choristomas involved the superotemporal limbus (6 of 10), although nasal (3 of 10) and inferior (1 of 10) limbal tumors also were present. Three patients had significant corneal astigmatism or involvement of the central cornea requiring surgical removal of their Choristomas, one accompanied by a lamellar keratoplasty and another accompanied by two consecutive penetrating keratoplasties. Each graft eventually vascularized, reducing vision. One patient's vision was limited by amblyopia and another by occipital cortical dysgenesis with visual impairment. Histopathologic examination of the excised Choristomas showed foci of lacrimal gland (3 of 4 patients), adipose tissue (3 of 4), neural tissue (1 of 4), cartilage (1 of 4), lymphoid follicles (1 of 4), skin adnexal tissue (1 of 4), and smooth muscle (1 of 4). Other associated ocular findings included an eyelid mass (1 of 4), colobomas of the eyelid (3 of 4), colobomas of the choroid and retina (2 of 4), nonparalytic strabismus (2 of 4), scleral ectasia (1 of 4), partial oculomotor palsy with ptosis and anisocoria (1 of 4), microphthalmia (1 of 4), and cortical visual impairment (1 of 4). Conclusions Complex limbal Choristomas, although rare, can occur in the setting of LNSS and can be associated with multiple ocular and systemic abnormalities. Visual prognosis appears poor in most cases despite aggressive management.
Juan S. Barajas-gamboa - One of the best experts on this subject based on the ideXlab platform.
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Complex Choristoma of the lacrimal caruncle: a case report of an unusual congenital tumor with clinical and histopathological classification
International Ophthalmology, 2012Co-Authors: Julio A. Diaz-perez, Juan S. Barajas-gamboaAbstract:Rare congenital tumors can be localized in the peribulbar area. Here we report an unusual case presented in a 3-year-old child with a history of a congenital tumor in the lacrimal caruncle of the right eye, associated with epiphora and constant discomfort. A surgical resection was performed, and the final histopathological diagnosis was lacrimal caruncle complex Choristoma. Choristomas are growths of apparently normal tissue in an abnormal location, which can be situated anywhere in the body, including ocular and peribulbar structures. These almost unknown congenital tumors constitute the most common conjunctival tumors in children and can be interpreted clinically as different lesions, which are only differentiated through precise histopathological analysis.