The Experts below are selected from a list of 25791 Experts worldwide ranked by ideXlab platform

Felipe Fregni - One of the best experts on this subject based on the ideXlab platform.

  • focal modulation of the primary motor cortex in fibromyalgia using 4 1 ring high definition transcranial direct current stimulation hd tdcs immediate and delayed analgesic effects of cathodal and anodal stimulation
    The Journal of Pain, 2013
    Co-Authors: Mauricio F Villama, Pako Wivatvongvana, Jayanto Patumanond, Marom Ikso, Dennis Q Truong, Abhishek Datta, Felipe Fregni
    Abstract:

    UNLABELLED: Fibromyalgia is a prevalent Chronic Pain Syndrome characterized by altered Pain and sensory processing in the central nervous system, which is often refractory to multiple therapeutic approaches. Given previous evidence supporting analgesic properties of noninvasive brain stimulation techniques in this condition, this study examined the effects of a novel, more focal method of transcranial direct current stimulation (tDCS), using the 4×1-ring configuration of high-definition (HD)-tDCS, on overall perceived Pain in fibromyalgia patients. In this patient- and assessor-blind, sham-controlled, crossover trial, 18 patients were randomized to undergo single 20-minute sessions of anodal, cathodal, and sham HD-tDCS at 2.0 mA in a counterbalanced fashion. The center electrode was positioned over the left primary motor cortex. Pain scales and sensory testing were assessed before and after each intervention. A finite element method brain model was generated to predict electric field distribution. We found that both active stimulation conditions led to significant reduction in overall perceived Pain as compared to sham. This effect occurred immediately after cathodal HD-tDCS and was evident for both anodal and cathodal HD-tDCS 30 minutes after stimulation. Furthermore, active anodal stimulation induced a significant bilateral increase in mechanical detection thresholds. These interventions proved well tolerated in our patient population. PERSPECTIVE: 4×1-ring HD-tDCS, a novel noninvasive brain stimulation technique capable of more focal and targeted stimulation, provides significant reduction in overall perceived Pain in fibromyalgia patients as compared to sham stimulation, irrespective of current polarity. This technique may have other applications in research and clinical settings, which should be further explored.

  • focal modulation of the primary motor cortex in fibromyalgia using 4 1 ring high definition transcranial direct current stimulation hd tdcs immediate and delayed analgesic effects of cathodal and anodal stimulation
    The Journal of Pain, 2013
    Co-Authors: Pako Wivatvongvana, Jayanto Patumanond, Dennis Q Truong, Abhishek Datta, Mauricio F Villamar, Marom Bikson, Felipe Fregni
    Abstract:

    Abstract Fibromyalgia is a prevalent Chronic Pain Syndrome characterized by altered Pain and sensory processing in the central nervous system, which is often refractory to multiple therapeutic approaches. Given previous evidence supporting analgesic properties of noninvasive brain stimulation techniques in this condition, this study examined the effects of a novel, more focal method of transcranial direct current stimulation (tDCS), using the 4×1-ring configuration of high-definition (HD)-tDCS, on overall perceived Pain in fibromyalgia patients. In this patient- and assessor-blind, sham-controlled, crossover trial, 18 patients were randomized to undergo single 20-minute sessions of anodal, cathodal, and sham HD-tDCS at 2.0 mA in a counterbalanced fashion. The center electrode was positioned over the left primary motor cortex. Pain scales and sensory testing were assessed before and after each intervention. A finite element method brain model was generated to predict electric field distribution. We found that both active stimulation conditions led to significant reduction in overall perceived Pain as compared to sham. This effect occurred immediately after cathodal HD-tDCS and was evident for both anodal and cathodal HD-tDCS 30 minutes after stimulation. Furthermore, active anodal stimulation induced a significant bilateral increase in mechanical detection thresholds. These interventions proved well tolerated in our patient population. Perspective 4×1-ring HD-tDCS, a novel noninvasive brain stimulation technique capable of more focal and targeted stimulation, provides significant reduction in overall perceived Pain in fibromyalgia patients as compared to sham stimulation, irrespective of current polarity. This technique may have other applications in research and clinical settings, which should be further explored.

Pako Wivatvongvana - One of the best experts on this subject based on the ideXlab platform.

  • focal modulation of the primary motor cortex in fibromyalgia using 4 1 ring high definition transcranial direct current stimulation hd tdcs immediate and delayed analgesic effects of cathodal and anodal stimulation
    The Journal of Pain, 2013
    Co-Authors: Mauricio F Villama, Pako Wivatvongvana, Jayanto Patumanond, Marom Ikso, Dennis Q Truong, Abhishek Datta, Felipe Fregni
    Abstract:

    UNLABELLED: Fibromyalgia is a prevalent Chronic Pain Syndrome characterized by altered Pain and sensory processing in the central nervous system, which is often refractory to multiple therapeutic approaches. Given previous evidence supporting analgesic properties of noninvasive brain stimulation techniques in this condition, this study examined the effects of a novel, more focal method of transcranial direct current stimulation (tDCS), using the 4×1-ring configuration of high-definition (HD)-tDCS, on overall perceived Pain in fibromyalgia patients. In this patient- and assessor-blind, sham-controlled, crossover trial, 18 patients were randomized to undergo single 20-minute sessions of anodal, cathodal, and sham HD-tDCS at 2.0 mA in a counterbalanced fashion. The center electrode was positioned over the left primary motor cortex. Pain scales and sensory testing were assessed before and after each intervention. A finite element method brain model was generated to predict electric field distribution. We found that both active stimulation conditions led to significant reduction in overall perceived Pain as compared to sham. This effect occurred immediately after cathodal HD-tDCS and was evident for both anodal and cathodal HD-tDCS 30 minutes after stimulation. Furthermore, active anodal stimulation induced a significant bilateral increase in mechanical detection thresholds. These interventions proved well tolerated in our patient population. PERSPECTIVE: 4×1-ring HD-tDCS, a novel noninvasive brain stimulation technique capable of more focal and targeted stimulation, provides significant reduction in overall perceived Pain in fibromyalgia patients as compared to sham stimulation, irrespective of current polarity. This technique may have other applications in research and clinical settings, which should be further explored.

  • focal modulation of the primary motor cortex in fibromyalgia using 4 1 ring high definition transcranial direct current stimulation hd tdcs immediate and delayed analgesic effects of cathodal and anodal stimulation
    The Journal of Pain, 2013
    Co-Authors: Pako Wivatvongvana, Jayanto Patumanond, Dennis Q Truong, Abhishek Datta, Mauricio F Villamar, Marom Bikson, Felipe Fregni
    Abstract:

    Abstract Fibromyalgia is a prevalent Chronic Pain Syndrome characterized by altered Pain and sensory processing in the central nervous system, which is often refractory to multiple therapeutic approaches. Given previous evidence supporting analgesic properties of noninvasive brain stimulation techniques in this condition, this study examined the effects of a novel, more focal method of transcranial direct current stimulation (tDCS), using the 4×1-ring configuration of high-definition (HD)-tDCS, on overall perceived Pain in fibromyalgia patients. In this patient- and assessor-blind, sham-controlled, crossover trial, 18 patients were randomized to undergo single 20-minute sessions of anodal, cathodal, and sham HD-tDCS at 2.0 mA in a counterbalanced fashion. The center electrode was positioned over the left primary motor cortex. Pain scales and sensory testing were assessed before and after each intervention. A finite element method brain model was generated to predict electric field distribution. We found that both active stimulation conditions led to significant reduction in overall perceived Pain as compared to sham. This effect occurred immediately after cathodal HD-tDCS and was evident for both anodal and cathodal HD-tDCS 30 minutes after stimulation. Furthermore, active anodal stimulation induced a significant bilateral increase in mechanical detection thresholds. These interventions proved well tolerated in our patient population. Perspective 4×1-ring HD-tDCS, a novel noninvasive brain stimulation technique capable of more focal and targeted stimulation, provides significant reduction in overall perceived Pain in fibromyalgia patients as compared to sham stimulation, irrespective of current polarity. This technique may have other applications in research and clinical settings, which should be further explored.

Abhishek Datta - One of the best experts on this subject based on the ideXlab platform.

  • focal modulation of the primary motor cortex in fibromyalgia using 4 1 ring high definition transcranial direct current stimulation hd tdcs immediate and delayed analgesic effects of cathodal and anodal stimulation
    The Journal of Pain, 2013
    Co-Authors: Mauricio F Villama, Pako Wivatvongvana, Jayanto Patumanond, Marom Ikso, Dennis Q Truong, Abhishek Datta, Felipe Fregni
    Abstract:

    UNLABELLED: Fibromyalgia is a prevalent Chronic Pain Syndrome characterized by altered Pain and sensory processing in the central nervous system, which is often refractory to multiple therapeutic approaches. Given previous evidence supporting analgesic properties of noninvasive brain stimulation techniques in this condition, this study examined the effects of a novel, more focal method of transcranial direct current stimulation (tDCS), using the 4×1-ring configuration of high-definition (HD)-tDCS, on overall perceived Pain in fibromyalgia patients. In this patient- and assessor-blind, sham-controlled, crossover trial, 18 patients were randomized to undergo single 20-minute sessions of anodal, cathodal, and sham HD-tDCS at 2.0 mA in a counterbalanced fashion. The center electrode was positioned over the left primary motor cortex. Pain scales and sensory testing were assessed before and after each intervention. A finite element method brain model was generated to predict electric field distribution. We found that both active stimulation conditions led to significant reduction in overall perceived Pain as compared to sham. This effect occurred immediately after cathodal HD-tDCS and was evident for both anodal and cathodal HD-tDCS 30 minutes after stimulation. Furthermore, active anodal stimulation induced a significant bilateral increase in mechanical detection thresholds. These interventions proved well tolerated in our patient population. PERSPECTIVE: 4×1-ring HD-tDCS, a novel noninvasive brain stimulation technique capable of more focal and targeted stimulation, provides significant reduction in overall perceived Pain in fibromyalgia patients as compared to sham stimulation, irrespective of current polarity. This technique may have other applications in research and clinical settings, which should be further explored.

  • focal modulation of the primary motor cortex in fibromyalgia using 4 1 ring high definition transcranial direct current stimulation hd tdcs immediate and delayed analgesic effects of cathodal and anodal stimulation
    The Journal of Pain, 2013
    Co-Authors: Pako Wivatvongvana, Jayanto Patumanond, Dennis Q Truong, Abhishek Datta, Mauricio F Villamar, Marom Bikson, Felipe Fregni
    Abstract:

    Abstract Fibromyalgia is a prevalent Chronic Pain Syndrome characterized by altered Pain and sensory processing in the central nervous system, which is often refractory to multiple therapeutic approaches. Given previous evidence supporting analgesic properties of noninvasive brain stimulation techniques in this condition, this study examined the effects of a novel, more focal method of transcranial direct current stimulation (tDCS), using the 4×1-ring configuration of high-definition (HD)-tDCS, on overall perceived Pain in fibromyalgia patients. In this patient- and assessor-blind, sham-controlled, crossover trial, 18 patients were randomized to undergo single 20-minute sessions of anodal, cathodal, and sham HD-tDCS at 2.0 mA in a counterbalanced fashion. The center electrode was positioned over the left primary motor cortex. Pain scales and sensory testing were assessed before and after each intervention. A finite element method brain model was generated to predict electric field distribution. We found that both active stimulation conditions led to significant reduction in overall perceived Pain as compared to sham. This effect occurred immediately after cathodal HD-tDCS and was evident for both anodal and cathodal HD-tDCS 30 minutes after stimulation. Furthermore, active anodal stimulation induced a significant bilateral increase in mechanical detection thresholds. These interventions proved well tolerated in our patient population. Perspective 4×1-ring HD-tDCS, a novel noninvasive brain stimulation technique capable of more focal and targeted stimulation, provides significant reduction in overall perceived Pain in fibromyalgia patients as compared to sham stimulation, irrespective of current polarity. This technique may have other applications in research and clinical settings, which should be further explored.

Vichai Vanadurongwan - One of the best experts on this subject based on the ideXlab platform.

  • restoration of elbow flexion in brachial plexus avulsion injury comparing spinal accessory nerve transfer with intercostal nerve transfer
    Journal of Hand Surgery (European Volume), 1999
    Co-Authors: Saranatra Waikakul, Saichol Wongtragul, Vichai Vanadurongwan
    Abstract:

    This study was performed to compare the clinical outcome of 2 types of commonly used nerve transfers, the spinal accessory nerve transfer and the intercostal nerve transfer. This study was a prospective randomized parallel trial involving 205 patients presenting between 1989 and 1994. All patients were males ranging in age from 16 to 43 years. All patients underwent surgery within 6 months of injury. Spinal accessory nerve transfer was performed in 130 patients; better results were obtained in terms of less operative time, fewer blood transfusions, fewer immediate complications, and better motor function (very good and good power in 83% of patients). Intercostal nerve transfer was performed in 75 patients; better results were observed in terms of earlier electromyographic evidence of motor reinnervation, improvement in protective sensation, and reduction of Pain. However, very good and good motor recovery was observed in only 64% of patients. There was no significant difference with regard to tidal volume, vital capacity, and the FEV1 to FEV ratio before and after surgery in either group. Smoking adversely affected the rate of recovery. Spinal accessory nerve transfer should be used when motor function of the elbow flexors is the major concern. Intercostal nerve transfer should be performed in patients who need both motor and sensory reconstruction and in those who have Chronic Pain Syndrome after brachial plexus injury.

  • restoration of elbow flexion in branchial plexus avulsion injury comparing spinal accessory nerve transfer with intercostal nerve transfer
    Journal of Hand Surgery (European Volume), 1999
    Co-Authors: Saranatra Waikakul, Saichol Wongtragul, Vichai Vanadurongwan
    Abstract:

    Abstract This study was performed to compare the clinical outcome of 2 types of commonly used nerve transfers, the spinal accessory nerve transfer and the intercostal nerve transfer. This study was a prospective randomized parallel trial involving 205 patients presenting between 1989 and 1994. All patients were males ranging in age from 16 to 43 years. All patients underwent surgery within 6 months of injury. Spinal accessory nerve transfer was performed in 130 patients; better results were obtained in terms of less operative time, fewer blood transfusions, fewer immediate complications, and better motor function (very good and good power in 83% of patients). Intercostal nerve transfer was performed in 75 patients; better results were observed in terms of earlier electromyographic evidence of motor reinnervation, improvement in protective sensation, and reduction of Pain. However, very good and good motor recovery was observed in only 64% of patients. There was no significant difference with regard to tidal volume, vital capacity, and the FEV 1 to FEV ratio before and after surgery in either group. Smoking adversely affected the rate of recovery. Spinal accessory nerve transfer should be used when motor function of the elbow flexors is the major concern. Intercostal nerve transfer should be performed in patients who need both motor and sensory reconstruction and in those who have Chronic Pain Syndrome after brachial plexus injury. (J Hand Surg 1999;24A:571–577. Copyright © 1999 by the American Society for Surgery of the Hand.)

Mauricio F Villama - One of the best experts on this subject based on the ideXlab platform.

  • focal modulation of the primary motor cortex in fibromyalgia using 4 1 ring high definition transcranial direct current stimulation hd tdcs immediate and delayed analgesic effects of cathodal and anodal stimulation
    The Journal of Pain, 2013
    Co-Authors: Mauricio F Villama, Pako Wivatvongvana, Jayanto Patumanond, Marom Ikso, Dennis Q Truong, Abhishek Datta, Felipe Fregni
    Abstract:

    UNLABELLED: Fibromyalgia is a prevalent Chronic Pain Syndrome characterized by altered Pain and sensory processing in the central nervous system, which is often refractory to multiple therapeutic approaches. Given previous evidence supporting analgesic properties of noninvasive brain stimulation techniques in this condition, this study examined the effects of a novel, more focal method of transcranial direct current stimulation (tDCS), using the 4×1-ring configuration of high-definition (HD)-tDCS, on overall perceived Pain in fibromyalgia patients. In this patient- and assessor-blind, sham-controlled, crossover trial, 18 patients were randomized to undergo single 20-minute sessions of anodal, cathodal, and sham HD-tDCS at 2.0 mA in a counterbalanced fashion. The center electrode was positioned over the left primary motor cortex. Pain scales and sensory testing were assessed before and after each intervention. A finite element method brain model was generated to predict electric field distribution. We found that both active stimulation conditions led to significant reduction in overall perceived Pain as compared to sham. This effect occurred immediately after cathodal HD-tDCS and was evident for both anodal and cathodal HD-tDCS 30 minutes after stimulation. Furthermore, active anodal stimulation induced a significant bilateral increase in mechanical detection thresholds. These interventions proved well tolerated in our patient population. PERSPECTIVE: 4×1-ring HD-tDCS, a novel noninvasive brain stimulation technique capable of more focal and targeted stimulation, provides significant reduction in overall perceived Pain in fibromyalgia patients as compared to sham stimulation, irrespective of current polarity. This technique may have other applications in research and clinical settings, which should be further explored.