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Kittiprakai Akkaratham - One of the best experts on this subject based on the ideXlab platform.
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Laryngopharyngeal Reflux Disease in Sanpatong Hospital, Chiang Mai
2012Co-Authors: Kittiprakai AkkarathamAbstract:Laryngopharyngeal reflux (LPR) was new founded disease that debated in pathophysiology,diagnosis, treatment. This disease was not life–threatening but could suffer patients by decreased quality of life and efficacy in working. We studied prevalence, signs, symptoms, Reflux symptom index (RSI),Reflux finding score (RFS) and co-factors. The retrospective cohort study included 3 years period (1 January 2009 to 31 December 2011). The study subjects were all laryngopharyngeal reflux outpatients. The results showed that there were total 121 laryngopharyngeal reflux patients included in the study (2.4 % of all ear nose Throats out patients). Mean age of these patients was 52.47 years. There were 92 females (76.03 %) and 29 males (23.97 %). The most three common occupational were generalize workers (56; 46.28 %), farmers (17; 14.05 %) and 15 housemaids (15; 12.40 %). Co-factors of this condition were fat diets (12 %), tomatoes,onion, mint, garlic, chocolate and coffee consumption (6.6 %), alcohol drinking (3 %) and multico-factors (21.3 %). Most common sign founded was globus sensation. Other signs were Chronic Sore Throat,hoarseness, cough and Throat clearing. LPR that was founded with heartburn and regurgitation was of 7.5 %. The mean score of RSI was 16.8 (the value of RSI for diagnosis LPR was greater than 13). The mean score of RFS was 8.6 (the value of RFS for diagnosis LPR was greater than 7). Most LPR patients received proton pump inhibitor with H2- receptor antagonist and lifestyle modification (90.9 %). Clinical improved within 3 months was found among 78 cases of patients (64.5 %). Recurrence was found in 5 cases (4.1 %). Eighty-six cases (71 %) reported having good lifestyle modification. Ten cases (8.26 %) were not improved and were referred for further investigations. In conclusion, physicians should be reminded of abnormal laryngeal signs of patients and suspected LPR. They also should be aware in looking for other causes of abnormal signs and symptoms of patients that may manifest clinical similarly to LPR especially cancers of larynx which are more life threatening when the wrong diagnosis has been made.
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Abstract : Laryngopharyngeal Reflux Disease in Sanpatong Hospital, Chiang Mai
2012Co-Authors: Kittiprakai AkkarathamAbstract:Laryngopharyngeal reflux (LPR) was new founded disease that debated in pathophysiology, diagnosis, treatment. This disease was not life–threatening but could suffer patients by decreased quality of life and efficacy in working. We studied prevalence, signs, symptoms, Reflux symptom index (RSI), Reflux finding score (RFS) and co-factors. The retrospective cohort study included 3 years period (1 January 2009 to 31 December 2011). The study subjects were all laryngopharyngeal reflux outpatients. The results showed that there were total 121 laryngopharyngeal reflux patients included in the study (2.4 % of all ear nose Throats out patients). Mean age of these patients was 52.47 years. There were 92 females (76.03 %) and 29 males (23.97 %). The most three common occupational were generalize workers (56; 46.28 %), farmers (17; 14.05 %) and 15 housemaids (15; 12.40 %). Co-factors of this condition were fat diets (12 %), tomatoes, onion, mint, garlic, chocolate and coffee consumption (6.6 %), alcohol drinking (3 %) and multico-factors (21.3 %). Most common sign founded was globus sensation. Other signs were Chronic Sore Throat, hoarseness, cough and Throat clearing. LPR that was founded with heartburn and regurgitation was of 7.5 %. The mean score of RSI was 16.8 (the value of RSI for diagnosis LPR was greater than 13). The mean score of RFS was 8.6 (the value of RFS for diagnosis LPR was greater than 7). Most LPR patients received proton pump inhibitor with H2- receptor antagonist and lifestyle modification (90.9 %). Clinical improved within 3 months was found among 78 cases of patients (64.5 %). Recurrence was found in 5 cases (4.1 %). Eighty-six cases (71 %) reported having good lifestyle modification. Ten cases (8.26 %) were not improved and were referred for further investigations. In conclusion, physicians should be reminded of abnormal laryngeal signs of patients and suspected LPR. They also should be aware in looking for other causes of abnormal signs and symptoms of patients that may manifest clinical similarly to LPR especially cancers of larynx which are more life threatening when the wrong diagnosis has been made.
Marlene L. Durand - One of the best experts on this subject based on the ideXlab platform.
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Chronic Sore Throat
Infections of the Ears Nose Throat and Sinuses, 2018Co-Authors: Marlene L. DurandAbstract:Chronic Sore Throat is usually caused by non-infectious processes, such as gastrointestinal reflux. Autoimmune diseases, such as pemphigus vulgaris and mucous membrane pemphigoid, are less common etiologies. Malignancy is important to exclude in any patient with Chronic Throat pain or hoarseness. Infectious causes of these symptoms include Mycobacterium tuberculosis and various types of fungi, such as Candida, Cryptococcus, and endemic fungi (Histoplasma, Blastomyces, Coccidioides, and Paracoccidioides). This chapter reviews the epidemiology and clinical manifestations of various non-infectious and infectious causes of Chronic Sore Throat.
Bhaskar Ghosh - One of the best experts on this subject based on the ideXlab platform.
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Encountering Chronic Sore Throat: How Challenging is it for the Otolaryngologists?
Indian Journal of Otolaryngology and Head & Neck Surgery, 2019Co-Authors: Sohag Kundu, Mainak Dutta, Bijan Kumar Adhikary, Bhaskar GhoshAbstract:Objective To explore and diagnose the underlying causes of Chronic, recalcitrant Sore Throat. Methodology In this descriptive, cross-sectional study spanning 3 years (January 2014–December 2016), 1580 patients with Chronic Sore Throat (>12 weeks duration, despite conventional medication) were evaluated for the possible cause(s) in a tertiary care teaching institute of eastern India, through proper history, appropriate investigations, and a self-designed algorithm. Results The common causes for Chronic Sore Throat were Chronic tonsillopharyngitis, gastroesophageal reflux disorder, submandibular sialadenitis, and laryngopharyngeal reflux disorder, respectively. Allergy, psychiatric illnesses, oral submucous fibrosis, systemic comorbidities (diabetes mellitus, hypothyroidism, uremia, arthritides), stylalgia, Koch’s pneumonitis, recurrent aphthous ulcers, and dietary deficiencies formed the other major causes. There was a minimal female preponderance, the female: male ratio being 1.25. About 39% patients were Chronic smokers, and 31% addicted to alcohol. Forty-three (2.72%) patients were reactive to HIV 1/2. Conclusion The study provided with a detailed account of the heterogeneous etiology of Chronic Sore Throat, and an overall structured idea on how to approach to its work-up and diagnosis. Proper history taking and appropriate structured investigations are the keys. Chronic tonsillopharyngitis, gastroesophageal reflux disorder, submandibular sialadenitis, and laryngopharyngeal reflux disorder were the chief causes of Chronic Sore Throat.
Lorenz F. Lassen - One of the best experts on this subject based on the ideXlab platform.
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Head and neck manifestations of gastroesophageal reflux disease.
American family physician, 1999Co-Authors: Vanita Ahuja, Myron W. Yencha, Lorenz F. LassenAbstract:Gastroesophageal reflux disease (GERD) is the most common esophageal disease. Besides the typical presentation of heartburn and acid regurgitation, either alone or in combination, GERD can cause atypical symptoms. An estimated 20 to 60 percent of patients with GERD have head and neck symptoms without any appreciable heartburn. While the most common head and neck symptom is a globus sensation (a lump in the Throat), the head and neck manifestations can be diverse and may be misleading in the initial work-up. Thus, a high index of suspicion is required. Laryngoscopy can confirm the diagnosis of laryngopharyngeal reflux. Erythema of the posterior larynx may be seen, and the true vocal cords may be edematous. Treatment should be initiated with a histamine H2 receptor blocker or proton pump inhibitor. Lifestyle changes are also beneficial. Untreated, GERD can lead to Chronic laryngitis, dysphonia, Chronic Sore Throat, Chronic cough, constant Throat clearing, granuloma of the true vocal cords and other problems.
Sohag Kundu - One of the best experts on this subject based on the ideXlab platform.
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Encountering Chronic Sore Throat: How Challenging is it for the Otolaryngologists?
Indian Journal of Otolaryngology and Head & Neck Surgery, 2019Co-Authors: Sohag Kundu, Mainak Dutta, Bijan Kumar Adhikary, Bhaskar GhoshAbstract:Objective To explore and diagnose the underlying causes of Chronic, recalcitrant Sore Throat. Methodology In this descriptive, cross-sectional study spanning 3 years (January 2014–December 2016), 1580 patients with Chronic Sore Throat (>12 weeks duration, despite conventional medication) were evaluated for the possible cause(s) in a tertiary care teaching institute of eastern India, through proper history, appropriate investigations, and a self-designed algorithm. Results The common causes for Chronic Sore Throat were Chronic tonsillopharyngitis, gastroesophageal reflux disorder, submandibular sialadenitis, and laryngopharyngeal reflux disorder, respectively. Allergy, psychiatric illnesses, oral submucous fibrosis, systemic comorbidities (diabetes mellitus, hypothyroidism, uremia, arthritides), stylalgia, Koch’s pneumonitis, recurrent aphthous ulcers, and dietary deficiencies formed the other major causes. There was a minimal female preponderance, the female: male ratio being 1.25. About 39% patients were Chronic smokers, and 31% addicted to alcohol. Forty-three (2.72%) patients were reactive to HIV 1/2. Conclusion The study provided with a detailed account of the heterogeneous etiology of Chronic Sore Throat, and an overall structured idea on how to approach to its work-up and diagnosis. Proper history taking and appropriate structured investigations are the keys. Chronic tonsillopharyngitis, gastroesophageal reflux disorder, submandibular sialadenitis, and laryngopharyngeal reflux disorder were the chief causes of Chronic Sore Throat.