The Experts below are selected from a list of 8499 Experts worldwide ranked by ideXlab platform
Alberto Beltramello - One of the best experts on this subject based on the ideXlab platform.
-
Clinical Target Volume delineation in glioblastomas pre operative versus post operative pre radiotherapy mri
British Journal of Radiology, 2011Co-Authors: Paolo Farace, Mariagrazia Giri, Gabriele Meliado, D Amelio, L Widesott, Giuseppe Ricciardi, Stefano Dalloglio, Aldosilvio Rizzotti, Andrea Sbarbati, Alberto BeltramelloAbstract:Objectives: Delineation of Clinical Target Volume (CTV) is still controversial in glioblastomas. In order to assess the differences in Volume and shape of the radiotherapy Target, the use of pre-operative vs post-operative/pre-radiotherapy T1 and T2 weighted MRI was compared. Methods: 4 CTVs were delineated in 24 patients pre-operatively and post-operatively using T1 contrast-enhanced (T1PRECTV and T1POSTCTV) and T2 weighted images (T2PRECTV and T2POSTCTV). Pre-operative MRI examinations were performed the day before surgery, whereas post-operative examinations were acquired 1 month after surgery and before chemoradiation. A concordance index (CI) was defined as the ratio between the overlapping and composite Volumes. Results: The Volumes of T1PRECTV and T1POSTCTV were not statistically different (248 i 88 vs 254 i 101), although Volume differences .100 cm 3 were observed in 6 out of 24 patients. A marked increase due to tumour progression was shown in three patients. Three patients showed a decrease because of a reduced mass effect. A significant reduction occurred between pre-operative and post-operative T2 Volumes (139 i 68 vs 78 i 59). Lack of concordance was observed between T1PRECTV and T1POSTCTV (CI50.67 i 0.09), T2PRECTV and T2POSTCTV (CI50.39 i 0.20) and comparing the portion of the T1PRECTV and T1POSTCTV not covered by that defined on T2PRECTV images (CI50.45 i 0.16 and 0.44 i 0.17, respectively). Conclusion :U singT2 MRI, huge variations can be observed in peritumoural oedema, which are probably due to steroid treatment. Using T1 MRI, brain shifts after surgery and possible progressive enhancing lesions produce substantial differences in CTVs. Our data support the use of post-operative/pre-radiotherapy T1weighted MRI for planning purposes.
-
Clinical Target Volume delineation in glioblastomas: pre-operative versus post-operative/pre-radiotherapy MRI
British Journal of Radiology, 2010Co-Authors: Paolo Farace, Mariagrazia Giri, Gabriele Meliado, D Amelio, L Widesott, Giuseppe Ricciardi, Aldosilvio Rizzotti, Andrea Sbarbati, Stefano Dall’oglio, Alberto BeltramelloAbstract:Objectives: Delineation of Clinical Target Volume (CTV) is still controversial in glioblastomas. In order to assess the differences in Volume and shape of the radiotherapy Target, the use of pre-operative vs post-operative/pre-radiotherapy T1 and T2 weighted MRI was compared. Methods: 4 CTVs were delineated in 24 patients pre-operatively and post-operatively using T1 contrast-enhanced (T1PRECTV and T1POSTCTV) and T2 weighted images (T2PRECTV and T2POSTCTV). Pre-operative MRI examinations were performed the day before surgery, whereas post-operative examinations were acquired 1 month after surgery and before chemoradiation. A concordance index (CI) was defined as the ratio between the overlapping and composite Volumes. Results: The Volumes of T1PRECTV and T1POSTCTV were not statistically different (248 i 88 vs 254 i 101), although Volume differences .100 cm 3 were observed in 6 out of 24 patients. A marked increase due to tumour progression was shown in three patients. Three patients showed a decrease because of a reduced mass effect. A significant reduction occurred between pre-operative and post-operative T2 Volumes (139 i 68 vs 78 i 59). Lack of concordance was observed between T1PRECTV and T1POSTCTV (CI50.67 i 0.09), T2PRECTV and T2POSTCTV (CI50.39 i 0.20) and comparing the portion of the T1PRECTV and T1POSTCTV not covered by that defined on T2PRECTV images (CI50.45 i 0.16 and 0.44 i 0.17, respectively). Conclusion :U singT2 MRI, huge variations can be observed in peritumoural oedema, which are probably due to steroid treatment. Using T1 MRI, brain shifts after surgery and possible progressive enhancing lesions produce substantial differences in CTVs. Our data support the use of post-operative/pre-radiotherapy T1weighted MRI for planning purposes.
Paolo Farace - One of the best experts on this subject based on the ideXlab platform.
-
Clinical Target Volume delineation in glioblastomas pre operative versus post operative pre radiotherapy mri
British Journal of Radiology, 2011Co-Authors: Paolo Farace, Mariagrazia Giri, Gabriele Meliado, D Amelio, L Widesott, Giuseppe Ricciardi, Stefano Dalloglio, Aldosilvio Rizzotti, Andrea Sbarbati, Alberto BeltramelloAbstract:Objectives: Delineation of Clinical Target Volume (CTV) is still controversial in glioblastomas. In order to assess the differences in Volume and shape of the radiotherapy Target, the use of pre-operative vs post-operative/pre-radiotherapy T1 and T2 weighted MRI was compared. Methods: 4 CTVs were delineated in 24 patients pre-operatively and post-operatively using T1 contrast-enhanced (T1PRECTV and T1POSTCTV) and T2 weighted images (T2PRECTV and T2POSTCTV). Pre-operative MRI examinations were performed the day before surgery, whereas post-operative examinations were acquired 1 month after surgery and before chemoradiation. A concordance index (CI) was defined as the ratio between the overlapping and composite Volumes. Results: The Volumes of T1PRECTV and T1POSTCTV were not statistically different (248 i 88 vs 254 i 101), although Volume differences .100 cm 3 were observed in 6 out of 24 patients. A marked increase due to tumour progression was shown in three patients. Three patients showed a decrease because of a reduced mass effect. A significant reduction occurred between pre-operative and post-operative T2 Volumes (139 i 68 vs 78 i 59). Lack of concordance was observed between T1PRECTV and T1POSTCTV (CI50.67 i 0.09), T2PRECTV and T2POSTCTV (CI50.39 i 0.20) and comparing the portion of the T1PRECTV and T1POSTCTV not covered by that defined on T2PRECTV images (CI50.45 i 0.16 and 0.44 i 0.17, respectively). Conclusion :U singT2 MRI, huge variations can be observed in peritumoural oedema, which are probably due to steroid treatment. Using T1 MRI, brain shifts after surgery and possible progressive enhancing lesions produce substantial differences in CTVs. Our data support the use of post-operative/pre-radiotherapy T1weighted MRI for planning purposes.
-
Clinical Target Volume delineation in glioblastomas: pre-operative versus post-operative/pre-radiotherapy MRI
British Journal of Radiology, 2010Co-Authors: Paolo Farace, Mariagrazia Giri, Gabriele Meliado, D Amelio, L Widesott, Giuseppe Ricciardi, Aldosilvio Rizzotti, Andrea Sbarbati, Stefano Dall’oglio, Alberto BeltramelloAbstract:Objectives: Delineation of Clinical Target Volume (CTV) is still controversial in glioblastomas. In order to assess the differences in Volume and shape of the radiotherapy Target, the use of pre-operative vs post-operative/pre-radiotherapy T1 and T2 weighted MRI was compared. Methods: 4 CTVs were delineated in 24 patients pre-operatively and post-operatively using T1 contrast-enhanced (T1PRECTV and T1POSTCTV) and T2 weighted images (T2PRECTV and T2POSTCTV). Pre-operative MRI examinations were performed the day before surgery, whereas post-operative examinations were acquired 1 month after surgery and before chemoradiation. A concordance index (CI) was defined as the ratio between the overlapping and composite Volumes. Results: The Volumes of T1PRECTV and T1POSTCTV were not statistically different (248 i 88 vs 254 i 101), although Volume differences .100 cm 3 were observed in 6 out of 24 patients. A marked increase due to tumour progression was shown in three patients. Three patients showed a decrease because of a reduced mass effect. A significant reduction occurred between pre-operative and post-operative T2 Volumes (139 i 68 vs 78 i 59). Lack of concordance was observed between T1PRECTV and T1POSTCTV (CI50.67 i 0.09), T2PRECTV and T2POSTCTV (CI50.39 i 0.20) and comparing the portion of the T1PRECTV and T1POSTCTV not covered by that defined on T2PRECTV images (CI50.45 i 0.16 and 0.44 i 0.17, respectively). Conclusion :U singT2 MRI, huge variations can be observed in peritumoural oedema, which are probably due to steroid treatment. Using T1 MRI, brain shifts after surgery and possible progressive enhancing lesions produce substantial differences in CTVs. Our data support the use of post-operative/pre-radiotherapy T1weighted MRI for planning purposes.
Gianluca Valentini - One of the best experts on this subject based on the ideXlab platform.
-
radiotherapy planning pet ct scanner performances in the definition of gross tumour Volume and Clinical Target Volume
European Journal of Nuclear Medicine and Molecular Imaging, 2005Co-Authors: Ernesto Brianzoni, G Rossi, Sergio Ancidei, Alfonso Berbellini, F Capoccetti, Carla Cidda, Paola Davenia, S Fattori, Gian Carlo Montini, Gianluca ValentiniAbstract:Purpose Positron emission tomography is the most advanced scintigraphic imaging technology and can be employed in the planning of radiation therapy (RT). The aim of this study was to evaluate the possible role of fused images (anatomical CT and functional FDG-PET), acquired with a dedicated PET/CT scanner, in delineating gross tumour Volume (GTV) and Clinical Target Volume (CTV) in selected patients and thus in facilitating RT planning.
-
Radiotherapy planning: PET/CT scanner performances in the definition of gross tumour Volume and Clinical Target Volume
European Journal of Nuclear Medicine and Molecular Imaging, 2005Co-Authors: Ernesto Brianzoni, G Rossi, Sergio Ancidei, Alfonso Berbellini, F Capoccetti, Carla Cidda, S Fattori, Gian Carlo Montini, Paola D’avenia, Gianluca ValentiniAbstract:Purpose Positron emission tomography is the most advanced scintigraphic imaging technology and can be employed in the planning of radiation therapy (RT). The aim of this study was to evaluate the possible role of fused images (anatomical CT and functional FDG-PET), acquired with a dedicated PET/CT scanner, in delineating gross tumour Volume (GTV) and Clinical Target Volume (CTV) in selected patients and thus in facilitating RT planning.
Mariagrazia Giri - One of the best experts on this subject based on the ideXlab platform.
-
Clinical Target Volume delineation in glioblastomas pre operative versus post operative pre radiotherapy mri
British Journal of Radiology, 2011Co-Authors: Paolo Farace, Mariagrazia Giri, Gabriele Meliado, D Amelio, L Widesott, Giuseppe Ricciardi, Stefano Dalloglio, Aldosilvio Rizzotti, Andrea Sbarbati, Alberto BeltramelloAbstract:Objectives: Delineation of Clinical Target Volume (CTV) is still controversial in glioblastomas. In order to assess the differences in Volume and shape of the radiotherapy Target, the use of pre-operative vs post-operative/pre-radiotherapy T1 and T2 weighted MRI was compared. Methods: 4 CTVs were delineated in 24 patients pre-operatively and post-operatively using T1 contrast-enhanced (T1PRECTV and T1POSTCTV) and T2 weighted images (T2PRECTV and T2POSTCTV). Pre-operative MRI examinations were performed the day before surgery, whereas post-operative examinations were acquired 1 month after surgery and before chemoradiation. A concordance index (CI) was defined as the ratio between the overlapping and composite Volumes. Results: The Volumes of T1PRECTV and T1POSTCTV were not statistically different (248 i 88 vs 254 i 101), although Volume differences .100 cm 3 were observed in 6 out of 24 patients. A marked increase due to tumour progression was shown in three patients. Three patients showed a decrease because of a reduced mass effect. A significant reduction occurred between pre-operative and post-operative T2 Volumes (139 i 68 vs 78 i 59). Lack of concordance was observed between T1PRECTV and T1POSTCTV (CI50.67 i 0.09), T2PRECTV and T2POSTCTV (CI50.39 i 0.20) and comparing the portion of the T1PRECTV and T1POSTCTV not covered by that defined on T2PRECTV images (CI50.45 i 0.16 and 0.44 i 0.17, respectively). Conclusion :U singT2 MRI, huge variations can be observed in peritumoural oedema, which are probably due to steroid treatment. Using T1 MRI, brain shifts after surgery and possible progressive enhancing lesions produce substantial differences in CTVs. Our data support the use of post-operative/pre-radiotherapy T1weighted MRI for planning purposes.
-
Clinical Target Volume delineation in glioblastomas: pre-operative versus post-operative/pre-radiotherapy MRI
British Journal of Radiology, 2010Co-Authors: Paolo Farace, Mariagrazia Giri, Gabriele Meliado, D Amelio, L Widesott, Giuseppe Ricciardi, Aldosilvio Rizzotti, Andrea Sbarbati, Stefano Dall’oglio, Alberto BeltramelloAbstract:Objectives: Delineation of Clinical Target Volume (CTV) is still controversial in glioblastomas. In order to assess the differences in Volume and shape of the radiotherapy Target, the use of pre-operative vs post-operative/pre-radiotherapy T1 and T2 weighted MRI was compared. Methods: 4 CTVs were delineated in 24 patients pre-operatively and post-operatively using T1 contrast-enhanced (T1PRECTV and T1POSTCTV) and T2 weighted images (T2PRECTV and T2POSTCTV). Pre-operative MRI examinations were performed the day before surgery, whereas post-operative examinations were acquired 1 month after surgery and before chemoradiation. A concordance index (CI) was defined as the ratio between the overlapping and composite Volumes. Results: The Volumes of T1PRECTV and T1POSTCTV were not statistically different (248 i 88 vs 254 i 101), although Volume differences .100 cm 3 were observed in 6 out of 24 patients. A marked increase due to tumour progression was shown in three patients. Three patients showed a decrease because of a reduced mass effect. A significant reduction occurred between pre-operative and post-operative T2 Volumes (139 i 68 vs 78 i 59). Lack of concordance was observed between T1PRECTV and T1POSTCTV (CI50.67 i 0.09), T2PRECTV and T2POSTCTV (CI50.39 i 0.20) and comparing the portion of the T1PRECTV and T1POSTCTV not covered by that defined on T2PRECTV images (CI50.45 i 0.16 and 0.44 i 0.17, respectively). Conclusion :U singT2 MRI, huge variations can be observed in peritumoural oedema, which are probably due to steroid treatment. Using T1 MRI, brain shifts after surgery and possible progressive enhancing lesions produce substantial differences in CTVs. Our data support the use of post-operative/pre-radiotherapy T1weighted MRI for planning purposes.
Andrea Sbarbati - One of the best experts on this subject based on the ideXlab platform.
-
Clinical Target Volume delineation in glioblastomas pre operative versus post operative pre radiotherapy mri
British Journal of Radiology, 2011Co-Authors: Paolo Farace, Mariagrazia Giri, Gabriele Meliado, D Amelio, L Widesott, Giuseppe Ricciardi, Stefano Dalloglio, Aldosilvio Rizzotti, Andrea Sbarbati, Alberto BeltramelloAbstract:Objectives: Delineation of Clinical Target Volume (CTV) is still controversial in glioblastomas. In order to assess the differences in Volume and shape of the radiotherapy Target, the use of pre-operative vs post-operative/pre-radiotherapy T1 and T2 weighted MRI was compared. Methods: 4 CTVs were delineated in 24 patients pre-operatively and post-operatively using T1 contrast-enhanced (T1PRECTV and T1POSTCTV) and T2 weighted images (T2PRECTV and T2POSTCTV). Pre-operative MRI examinations were performed the day before surgery, whereas post-operative examinations were acquired 1 month after surgery and before chemoradiation. A concordance index (CI) was defined as the ratio between the overlapping and composite Volumes. Results: The Volumes of T1PRECTV and T1POSTCTV were not statistically different (248 i 88 vs 254 i 101), although Volume differences .100 cm 3 were observed in 6 out of 24 patients. A marked increase due to tumour progression was shown in three patients. Three patients showed a decrease because of a reduced mass effect. A significant reduction occurred between pre-operative and post-operative T2 Volumes (139 i 68 vs 78 i 59). Lack of concordance was observed between T1PRECTV and T1POSTCTV (CI50.67 i 0.09), T2PRECTV and T2POSTCTV (CI50.39 i 0.20) and comparing the portion of the T1PRECTV and T1POSTCTV not covered by that defined on T2PRECTV images (CI50.45 i 0.16 and 0.44 i 0.17, respectively). Conclusion :U singT2 MRI, huge variations can be observed in peritumoural oedema, which are probably due to steroid treatment. Using T1 MRI, brain shifts after surgery and possible progressive enhancing lesions produce substantial differences in CTVs. Our data support the use of post-operative/pre-radiotherapy T1weighted MRI for planning purposes.
-
Clinical Target Volume delineation in glioblastomas: pre-operative versus post-operative/pre-radiotherapy MRI
British Journal of Radiology, 2010Co-Authors: Paolo Farace, Mariagrazia Giri, Gabriele Meliado, D Amelio, L Widesott, Giuseppe Ricciardi, Aldosilvio Rizzotti, Andrea Sbarbati, Stefano Dall’oglio, Alberto BeltramelloAbstract:Objectives: Delineation of Clinical Target Volume (CTV) is still controversial in glioblastomas. In order to assess the differences in Volume and shape of the radiotherapy Target, the use of pre-operative vs post-operative/pre-radiotherapy T1 and T2 weighted MRI was compared. Methods: 4 CTVs were delineated in 24 patients pre-operatively and post-operatively using T1 contrast-enhanced (T1PRECTV and T1POSTCTV) and T2 weighted images (T2PRECTV and T2POSTCTV). Pre-operative MRI examinations were performed the day before surgery, whereas post-operative examinations were acquired 1 month after surgery and before chemoradiation. A concordance index (CI) was defined as the ratio between the overlapping and composite Volumes. Results: The Volumes of T1PRECTV and T1POSTCTV were not statistically different (248 i 88 vs 254 i 101), although Volume differences .100 cm 3 were observed in 6 out of 24 patients. A marked increase due to tumour progression was shown in three patients. Three patients showed a decrease because of a reduced mass effect. A significant reduction occurred between pre-operative and post-operative T2 Volumes (139 i 68 vs 78 i 59). Lack of concordance was observed between T1PRECTV and T1POSTCTV (CI50.67 i 0.09), T2PRECTV and T2POSTCTV (CI50.39 i 0.20) and comparing the portion of the T1PRECTV and T1POSTCTV not covered by that defined on T2PRECTV images (CI50.45 i 0.16 and 0.44 i 0.17, respectively). Conclusion :U singT2 MRI, huge variations can be observed in peritumoural oedema, which are probably due to steroid treatment. Using T1 MRI, brain shifts after surgery and possible progressive enhancing lesions produce substantial differences in CTVs. Our data support the use of post-operative/pre-radiotherapy T1weighted MRI for planning purposes.