The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform
John Oropello - One of the best experts on this subject based on the ideXlab platform.
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Staphylococcus lugdunensis the Coagulase Negative Staphylococcus you don t want to ignore
Expert Review of Anti-infective Therapy, 2011Co-Authors: Elizabeth Babu, John OropelloAbstract:Staphylococcus lugdunensis is a virulent Coagulase-Negative Staphylococcus (CoNS) that behaves like Staphylococcus aureus. Toxic shock syndrome, osteomyelitis, septic arthritis and postoperative endopthalmitis have been observed. Endocarditis complicated by heart failure, periannular abscess formation and embolic phenomenon have brought particular attention to this CoNS. Mortality rates for endocarditis appear higher when compared with other CoNS. Owing to the laboratory methods used, identification may be misleading. β-lactam antimicrobials are recommended pending sensitivities. Evaluation for endocarditis should be pursued in bacteremic patients due to its pathogenic potential.
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Staphylococcus lugdunensis: the Coagulase-Negative Staphylococcus you don’t want to ignore
Expert review of anti-infective therapy, 2011Co-Authors: Elizabeth Babu, John OropelloAbstract:Staphylococcus lugdunensis is a virulent Coagulase-Negative Staphylococcus (CoNS) that behaves like Staphylococcus aureus. Toxic shock syndrome, osteomyelitis, septic arthritis and postoperative endopthalmitis have been observed. Endocarditis complicated by heart failure, periannular abscess formation and embolic phenomenon have brought particular attention to this CoNS. Mortality rates for endocarditis appear higher when compared with other CoNS. Owing to the laboratory methods used, identification may be misleading. β-lactam antimicrobials are recommended pending sensitivities. Evaluation for endocarditis should be pursued in bacteremic patients due to its pathogenic potential.
Yoshikazu Shimomura - One of the best experts on this subject based on the ideXlab platform.
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methicillin resistant Staphylococcus aureus and methicillin resistant Coagulase Negative Staphylococcus ocular surface infection efficacy of chloramphenicol eye drops
Cornea, 2002Co-Authors: Masahiko Fukuda, Hideyuki Ohashi, Chota Matsumoto, Soichiro Mishima, Yoshikazu ShimomuraAbstract:Purpose. Methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Coagulase-Negative Staphylococcus (MR-CNS) are two major multidrug-resistant pathogens. In this paper we report the prevalence of MRSA and MR-CNS in ocular surface infections. Methods. We investigated the proportion of MRSA and MR-CNS in bacterial isolates from conjunctiva of elderly patients with and without bacterial conjunctivitis. The relationship between conjunctival MRSA carriers and general background conditions was studied. We evaluated the efficacy of chloramphenicol eye drops in the treatment of MRSA conjunctivitis. We also investigated the presence of MRSA and MR-CNS in lid skin and conjunctiva of patients with atopic dermatitis. Results. In conjunctival bacterial flora of elderly patients the proportion of MRSA in S. aureus was 57%, and the proportion of MR-CNS in Coagulase-Negative Staphylococcus was 25%. Conjunctival MRSA carriers were more likely to have anemia, malignant tumor, liver dysfunction, and dementia, and to be postoperation and chronically bedridden. The efficacy rate of chloramphenicol eye drops in the treatment of MRSA conjunctivitis was 81%. In conjunctival sacs of patients with atopic dermatitis, S. aureus was the most frequent species (48%), and the proportion of MRSA was 18%. Conclusion. Methicillin-resistant S. aureus and MR-CNS are widespread in elderly hospitalized patients and in patients with atopic dermatitis. Chloramphenicol eye drops were useful for the treatment of MRSA ocular surface infections.
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Methicillin-resistant Staphylococcus aureus and methicillin-resistant Coagulase-Negative Staphylococcus ocular surface infection efficacy of chloramphenicol eye drops.
Cornea, 2002Co-Authors: Masahiko Fukuda, Hideyuki Ohashi, Chota Matsumoto, Soichiro Mishima, Yoshikazu ShimomuraAbstract:Methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Coagulase-Negative Staphylococcus (MR-CNS) are two major multidrug-resistant pathogens. In this paper we report the prevalence of MRSA and MR-CNS in ocular surface infections. We investigated the proportion of MRSA and MR-CNS in bacterial isolates from conjunctiva of elderly patients with and without bacterial conjunctivitis. The relationship between conjunctival MRSA carriers and general background conditions was studied. We evaluated the efficacy of chloramphenicol eye drops in the treatment of MRSA conjunctivitis. We also investigated the presence of MRSA and MR-CNS in lid skin and conjunctiva of patients with atopic dermatitis. In conjunctival bacterial flora of elderly patients the proportion of MRSA in S. aureus was 57%, and the proportion of MR-CNS in Coagulase-Negative Staphylococcus was 25%. Conjunctival MRSA carriers were more likely to have anemia, malignant tumor, liver dysfunction, and dementia, and to be postoperation and chronically bedridden. The efficacy rate of chloramphenicol eye drops in the treatment of MRSA conjunctivitis was 81%. In conjunctival sacs of patients with atopic dermatitis, S. aureus was the most frequent species (48%), and the proportion of MRSA was 18%. Methicillin-resistant S. aureus and MR-CNS are widespread in elderly hospitalized patients and in patients with atopic dermatitis. Chloramphenicol eye drops were useful for the treatment of MRSA ocular surface infections.
S. P. Oliver - One of the best experts on this subject based on the ideXlab platform.
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Prevalence and persistence of Coagulase-Negative Staphylococcus species in three dairy research herds.
Veterinary Microbiology, 2008Co-Authors: Barbara E. Gillespie, Susan I. Headrick, S. Boonyayatra, S. P. OliverAbstract:Coagulase-Negative Staphylococcus species (CNS) were isolated from 11.3% (1407 of 12,412) of mammary quarter milk samples obtained from cows in three dairy research herds in 2005. Approximately 27% (383/1407) of CNS was identified to the species level. The species distribution among those CNS identified from all herds was Staphylococcus chromogenes (48%), Staphylococcus hyicus (26%), Staphylococcus epidermidis (10%), Staphylococcus simulans (7%), Staphylococcus wameri (2%), Staphylococcus hominis (2%), Staphylococcus saprophyticus (1%), Staphylococcus xylosus (1%), Staphylococcus haemolyticus (
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Identification and differentiation of Coagulase-Negative Staphylococcus aureus by polymerase chain reaction
Journal of food protection, 1997Co-Authors: Karl R. Matthews, Barbara E. Gillespie, J. Roberson, D. A. Luther, S. P. OliverAbstract:Staphylococcus aureus is an etiological agent of a wide variety of human and animal infections. The majority of S. aureus are Coagulase-positive; however, some may be atypical in that they do not produce Coagulase. Incorrect identification of an isolate can impact implementation of effective treatment and/or control measures. In this study, polymerase chain reaction-based DNA fingerprinting was used to differentiate Coagulase-positive Staphylococcus aureus (CPSA) from Coagulase-Negative Staphylococcus aureus (CNSA). A total of 29 CNSA and 50 CPSA were evaluated. PCR-based DNA fingerprinting differentiated CNSA from CPSA on the basis of visible observation and densitometric evaluation. The method is rapid and accurate, eliminating variability associated with conventional techniques.
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Expression of glycocalyx by Coagulase‐Negative Staphylococcus species isolated from bovine milk
The Journal of applied bacteriology, 1991Co-Authors: Karl R. Matthews, S. P. Oliver, S. H. KingAbstract:Two hundred and six strains of Coagulase-Negative Staphylococcus species were assessed for expression of glycocalyx on serum soft agar, india ink and adherence techniques. The organisms were maintained on trypticase soy agar plates at 4 degrees C for 30 d (120 strains) or stored at -80 degrees C in skim milk for 90 d (60 strains). Additionally, 26 milk samples from cows known to have excreted Coagulase-Negative staphylococci were used to inoculate serum soft agar directly. Nine of 26 direct culture samples and 43 of 180 strains maintained for an extended period had diffuse-type growth on serum soft agar. The proportion that exhibited an unstained halo by india ink was similar regardless of storage time. Slime production determined by in vitro adherence revealed a higher proportion of positive strains than had been predicted by serum soft agar or india ink techniques. More strains of Staphylococcus chromogenes, Staph. epidermidis, Staph. hominis, Staph. simulans and Staph. warneri expressed glycocalyx than other Coagulase-Negative Staphylococcus species. These results suggest that most Coagulase-Negative staphylococci produce slime rather than a capsule. However, evidence for classical encapsulation was demonstrated in several strains by india ink. The finding that Staphylococcus species other than Staph. aureus isolated from bovine milk are capable of glycocalyx production may be of importance in investigations on the relationship between staphylococci and host defence mechanisms.
Elizabeth Babu - One of the best experts on this subject based on the ideXlab platform.
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Staphylococcus lugdunensis the Coagulase Negative Staphylococcus you don t want to ignore
Expert Review of Anti-infective Therapy, 2011Co-Authors: Elizabeth Babu, John OropelloAbstract:Staphylococcus lugdunensis is a virulent Coagulase-Negative Staphylococcus (CoNS) that behaves like Staphylococcus aureus. Toxic shock syndrome, osteomyelitis, septic arthritis and postoperative endopthalmitis have been observed. Endocarditis complicated by heart failure, periannular abscess formation and embolic phenomenon have brought particular attention to this CoNS. Mortality rates for endocarditis appear higher when compared with other CoNS. Owing to the laboratory methods used, identification may be misleading. β-lactam antimicrobials are recommended pending sensitivities. Evaluation for endocarditis should be pursued in bacteremic patients due to its pathogenic potential.
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Staphylococcus lugdunensis: the Coagulase-Negative Staphylococcus you don’t want to ignore
Expert review of anti-infective therapy, 2011Co-Authors: Elizabeth Babu, John OropelloAbstract:Staphylococcus lugdunensis is a virulent Coagulase-Negative Staphylococcus (CoNS) that behaves like Staphylococcus aureus. Toxic shock syndrome, osteomyelitis, septic arthritis and postoperative endopthalmitis have been observed. Endocarditis complicated by heart failure, periannular abscess formation and embolic phenomenon have brought particular attention to this CoNS. Mortality rates for endocarditis appear higher when compared with other CoNS. Owing to the laboratory methods used, identification may be misleading. β-lactam antimicrobials are recommended pending sensitivities. Evaluation for endocarditis should be pursued in bacteremic patients due to its pathogenic potential.
John A. Costin - One of the best experts on this subject based on the ideXlab platform.
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Coagulase-Negative Staphylococcus endophthalmitis after cataract surgery with intraocular vancomycin.
American journal of ophthalmology, 1996Co-Authors: William A. Townsend-pico, Sanford M. Meyers, Roger H.s. Langston, John A. CostinAbstract:Purpose We studied a case of postoperative Coagulase-Negative Staphylococcus endophthalmitis in a 79-year-old man who had undergone cataract extraction in which vancomycin had been used intraoperatively in the infusion fluid. Methods The medical records were reviewed for the clinical history, ocular findings, and the vitreous and anterior chamber culture results. Results Acute, postoperative Coagulase-Negative Staphylococcus endophthalmitis developed in the patient in whom vancomycin had been used intraoperatively in the infusion fluid. Conclusions Restraint is urged in the prophylactic use of vancomycin in the infusion fluids.