The Experts below are selected from a list of 12 Experts worldwide ranked by ideXlab platform
F. Waffarn - One of the best experts on this subject based on the ideXlab platform.
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Noninvasive monitoring of Colon Blood Flow
Images of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society, 1Co-Authors: D.r. Gerstmann, F. WaffarnAbstract:The applicability of using an inert tracer gas to measure intestinal Blood Flow is investigated. The results from studies carried out to demonstrate that the pulmonary clearance of an inert noncombustible gas (helium) instilled into the Colon changes predictably with Colon Blood Flow (CBF) are presented. The results indicate that pulmonary clearance of the tracer gas follows expected changes in Colon Blood Flow during hypoxia, hypovolemic hypotension,and vascular occlusion and correlates well with Colon Blood Flow measured by radiolabeled microspheres. >
D.r. Gerstmann - One of the best experts on this subject based on the ideXlab platform.
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Noninvasive monitoring of Colon Blood Flow
Images of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society, 1Co-Authors: D.r. Gerstmann, F. WaffarnAbstract:The applicability of using an inert tracer gas to measure intestinal Blood Flow is investigated. The results from studies carried out to demonstrate that the pulmonary clearance of an inert noncombustible gas (helium) instilled into the Colon changes predictably with Colon Blood Flow (CBF) are presented. The results indicate that pulmonary clearance of the tracer gas follows expected changes in Colon Blood Flow during hypoxia, hypovolemic hypotension,and vascular occlusion and correlates well with Colon Blood Flow measured by radiolabeled microspheres. >
David Gibb - One of the best experts on this subject based on the ideXlab platform.
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An assessment of tonometry and regional splanchnic Blood Flow during aortic cross-clamping in the pig.
Anaesthesia and intensive care, 1996Co-Authors: T. Jacques, Rw Morris, R. Englund, David GibbAbstract:We aimed to evaluate the tonometer in the assessment of gastrointestinal ischaemia induced by an infrarenal aortic cross-clamp. Nine anaesthetized pigs were cannulated for haemodynamic monitoring and radionuclide labelled microsphere (RLM) injection. Gastric and sigmoid tonometers were positioned. After haemodynamic stabilization an infrarenal aortic cross-clamp was applied. Animals were sacrificed at the completion of the study and tissue sampled from the stomach and sigmoid Colon for regional Blood Flow measurements. Measurements were made pre-clamp, post-clamp, pre-release and post-release. Haemodynamic parameters, gastric intramucosal pH (pHi) and Blood Flow did not change throughout the experiment. Arterial pH increased during cross-clamp and returned to baseline post-release. Arterial bicarbonate fell post release. Sigmoid Blood Flow fell during cross-clamp. The sigmoid pHi fall, delayed until pre-release, remained low post-release. Although there was a consistent fall in sigmoid pHi, 63% of post-clamp values remained within the baseline range. We conclude that maintaining haemodynamic parameters around baseline values resulted in maintenance of gastric mucosal perfusion as indicated by a steady gastric pHi. However, below the aortic cross-clamp, delay between change in sigmoid Colon Blood Flow and change in pHi and wide variation in sigmoid pHi limits the value of an individual pHi measurement in detecting ischaemia.
T. Jacques - One of the best experts on this subject based on the ideXlab platform.
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An assessment of tonometry and regional splanchnic Blood Flow during aortic cross-clamping in the pig.
Anaesthesia and intensive care, 1996Co-Authors: T. Jacques, Rw Morris, R. Englund, David GibbAbstract:We aimed to evaluate the tonometer in the assessment of gastrointestinal ischaemia induced by an infrarenal aortic cross-clamp. Nine anaesthetized pigs were cannulated for haemodynamic monitoring and radionuclide labelled microsphere (RLM) injection. Gastric and sigmoid tonometers were positioned. After haemodynamic stabilization an infrarenal aortic cross-clamp was applied. Animals were sacrificed at the completion of the study and tissue sampled from the stomach and sigmoid Colon for regional Blood Flow measurements. Measurements were made pre-clamp, post-clamp, pre-release and post-release. Haemodynamic parameters, gastric intramucosal pH (pHi) and Blood Flow did not change throughout the experiment. Arterial pH increased during cross-clamp and returned to baseline post-release. Arterial bicarbonate fell post release. Sigmoid Blood Flow fell during cross-clamp. The sigmoid pHi fall, delayed until pre-release, remained low post-release. Although there was a consistent fall in sigmoid pHi, 63% of post-clamp values remained within the baseline range. We conclude that maintaining haemodynamic parameters around baseline values resulted in maintenance of gastric mucosal perfusion as indicated by a steady gastric pHi. However, below the aortic cross-clamp, delay between change in sigmoid Colon Blood Flow and change in pHi and wide variation in sigmoid pHi limits the value of an individual pHi measurement in detecting ischaemia.
Rw Morris - One of the best experts on this subject based on the ideXlab platform.
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An assessment of tonometry and regional splanchnic Blood Flow during aortic cross-clamping in the pig.
Anaesthesia and intensive care, 1996Co-Authors: T. Jacques, Rw Morris, R. Englund, David GibbAbstract:We aimed to evaluate the tonometer in the assessment of gastrointestinal ischaemia induced by an infrarenal aortic cross-clamp. Nine anaesthetized pigs were cannulated for haemodynamic monitoring and radionuclide labelled microsphere (RLM) injection. Gastric and sigmoid tonometers were positioned. After haemodynamic stabilization an infrarenal aortic cross-clamp was applied. Animals were sacrificed at the completion of the study and tissue sampled from the stomach and sigmoid Colon for regional Blood Flow measurements. Measurements were made pre-clamp, post-clamp, pre-release and post-release. Haemodynamic parameters, gastric intramucosal pH (pHi) and Blood Flow did not change throughout the experiment. Arterial pH increased during cross-clamp and returned to baseline post-release. Arterial bicarbonate fell post release. Sigmoid Blood Flow fell during cross-clamp. The sigmoid pHi fall, delayed until pre-release, remained low post-release. Although there was a consistent fall in sigmoid pHi, 63% of post-clamp values remained within the baseline range. We conclude that maintaining haemodynamic parameters around baseline values resulted in maintenance of gastric mucosal perfusion as indicated by a steady gastric pHi. However, below the aortic cross-clamp, delay between change in sigmoid Colon Blood Flow and change in pHi and wide variation in sigmoid pHi limits the value of an individual pHi measurement in detecting ischaemia.