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Jin Hak Lee - One of the best experts on this subject based on the ideXlab platform.

  • a new Color Vision test to differentiate congenital and acquired Color Vision Defects
    Ophthalmology, 2007
    Co-Authors: Young Joo Shin, Kyu Hyung Park, Jeong-min Hwang, Won Ryang Wee, Jin Hak Lee
    Abstract:

    Purpose To investigate the efficacy of a novel computer-controlled Color test for the differentiation of congenital and acquired Color Vision deficiency. Design Observational cross-sectional study. Participants Thirty-one patients with congenital Color Vision deficiency and 134 patients with acquired Color Vision deficiency with a Snellen visual acuity better than 20/30 underwent an ophthalmologic examination including the Ishihara Color test, Hardy-Rand-Rittler test, Nagel anomaloscopy, and the Seohan computerized hue test between June, 2003, and January, 2004. Methods To investigate the type of Color Vision Defect, a graph of the Seohan computerized hue test was divided into 4 quadrants and error scores in each quadrant were summated. The ratio between the sums of error scores of quadrants I and III (Q1+Q3) and those of quadrants II and IV (Q2+Q4) was calculated. Main Outcome Measures Error scores and ratio in quadrant analysis of the Seohan computerized hue test. Results The Seohan computerized hue test showed that the sum of Q2+Q4 was significantly higher than the sum of Q1+Q3 in congenital Color Vision deficiency ( P t test) and that the sum of Q2+Q4 was significantly lower than the sum of Q1+Q3 in acquired Color Vision deficiency ( P t test). In terms of discriminating congenital and acquired Color Vision deficiency, the ratio in quadrant analysis had 93.3% sensitivity and 98.5% specificity with a reference value of 1.5 by the Seohan computerized hue test (95% confidence interval). Conclusions The quadrant analysis and ratio of (Q2+Q4)/(Q1+Q3) using the Seohan computerized hue test effectively differentiated congenital and acquired Color Vision deficiency.

  • efficacy of the computer program to compensate Color Vision deficiency using seohan computerized 85 hue test
    Journal of The Korean Ophthalmological Society, 2006
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, Seung Ji Yang
    Abstract:

    Purpose: to study the utility of a program which diagnoses and compensates for Color Defects on computer monitors according to the severity and type of Color Vision deficiency (CVD). Methods: Twenty-eight patients with congenital CVD completed Seohan computerized hue test, Color compensated Seohan computerized hue test and questionnaire for preference of Color compensated images. The relation between results of the Seohan computerized hue test and the degrees of Color compensation was investigated. HRR test and Nagel anomaloscope were used for determining the severity and type of CVD. Results: In applying the Color compensation program, the total error score (TES) of the Seohan computerized hue test was significantly reduced. In cases of milder Color Vision Defect, the TES of the Color compensated Seohan computerized hue test was reduced at lower Color compensations, while it was reduced at higher Color compensations in cases of more severe Color Vision Defect. In the Color compensation of images, patients with milder Color Vision Defects preferred images with lower Color compensation and patients with more severe Color Vision Defect preferred images with higher Color compensation. Conclusions: The Color compensation program for CVD effectively reduced the TES of Seohan computerized hue tests and improved the recognition of Colors. This suggests that the program can be helpful to actual life in patients with CVD.

  • the discriminatiuon between congenital and acquired Color Vision Defects by computerized Color Vision test
    Journal of The Korean Ophthalmological Society, 2005
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, In Bum Lee, Sang Yul Choi, Kyu Hyoung Park, Min Seoup Kim, Jeoung Min Hwang, Jae Hee Choi
    Abstract:

    Purpose: To investigate the characteristics of congenital and acquired Color Vision Defects with Seohan computerized hue test and SNU (Seoul National University) computerized Color test and to help to discriminate between congenital and acquired Color Vision Defect Methods: from June 2003 to January 2004, patient with congenital and acquired Color Vision Defect and visual acuities more than 20/30 underwent Seohan computerized hue and SNU computerized Color tests. Their results were compared with each other. Quadrant analysis and RQ calculation were done. Results: On Seohan computerized hue and SNU computerized Color tests, congenital Color Vision Defects showed mainly red-green Color Vision Defects (p

  • Color Vision Defect in diabetic retinopathy by snu computerized Color test
    Journal of The Korean Ophthalmological Society, 2005
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, In Bum Lee, Sang Yul Choi, Kyu Hyoung Park, Min Seoup Kim, Jeoung Min Hwang, Meena Lee, Seoungmin Joo
    Abstract:

    Purpose: To investigate the Color Vision Defect in diabetic patients using the SNU computerized Color test (SCCT). Methods: From May to September 2003, diabetic patients with visual acuity 0.6 or better underwent various examinations including biomicroscopy, fundus photography, Ishihara Color test, Hardy‐Rand‐Rittler (HRR) test, Seohan computerized hue test (SCHT), and SNU computerized Color test. The SCCT was developed by using the Matlab 6.0 program. Results: A total of 160 eyes of 82 diabetic patients were included. Thirty‐two patients had no diabetic retinopathy, 19 had mild nonproliferative diabetic retinopathy (NPDR), 12 had moderate NPDR, 12 had severe NPDR, and 7 had proliferative diabetic retinopathy (PDR). In the all diabetic patients, the average total error score (TES) of SCHT was 189 and that of SCCT was 8.5; in patients without diabetic retinopathy, the scores were 125 and 3.64; in patients with mild NPDR, 185 and 8.16; in patients with moderate NPDR, 209 and 11.1; in patients with severe NPDR, 288 and 15.6 ; and in patients with PDR, 324 and 17.6 respectively. On the HRR test, patients without diabetic retinopathy had 1 tritan Defect; those with mild NPDR 2 tritan, 2 protan, and 2 deutan Defects : those with moderate NPDR, no Color Defects ; and those with severe NPDR, 2 tritan, and 2 protan Defects, and 1 deutan Defect. Conclusions: In diabetic patients, TES of SCHT and SCCT was higher according to the severity of diabetic retinopathy. SCHT and SCCT were more useful than HRR test.

Adam M Dubis - One of the best experts on this subject based on the ideXlab platform.

  • cone photoreceptor structure in patients with x linked cone dysfunction and red green Color Vision deficiency
    Investigative Ophthalmology & Visual Science, 2016
    Co-Authors: Emily J Patterson, Melissa A Wilk, Christopher S Langlo, Melissa Kasilian, Michael Ring, Robert B Hufnagel, Adam M Dubis
    Abstract:

    Purpose: Mutations in the coding sequence of the L and M opsin genes are often associated with X-linked cone dysfunction (such as Bornholm Eye Disease, BED), though the exact Color Vision phenotype associated with these disorders is variable. We examined individuals with L/M opsin gene mutations to clarify the link between Color Vision deficiency and cone dysfunction. Methods: We recruited 17 males for imaging. The thickness and integrity of the photoreceptor layers were evaluated using spectral-domain optical coherence tomography. Cone density was measured using high-resolution images of the cone mosaic obtained with adaptive optics scanning light ophthalmoscopy. The L/M opsin gene array was characterized in 16 subjects, including at least one subject from each family. Results: There were six subjects with the LVAVA haplotype encoded by exon 3, seven with LIAVA, two with the Cys203Arg mutation encoded by exon 4, and two with a novel insertion in exon 2. Foveal cone structure and retinal thickness was disrupted to a variable degree, even among related individuals with the same L/M array. Conclusions: Our findings provide a direct link between disruption of the cone mosaic and L/M opsin variants. We hypothesize that, in addition to large phenotypic differences between different L/M opsin variants, the ratio of expression of first versus downstream genes in the L/M array contributes to phenotypic diversity. While the L/M opsin mutations underlie the cone dysfunction in all of the subjects tested, the Color Vision Defect can be caused either by the same mutation or a gene rearrangement at the same locus.

Young Joo Shin - One of the best experts on this subject based on the ideXlab platform.

  • a new Color Vision test to differentiate congenital and acquired Color Vision Defects
    Ophthalmology, 2007
    Co-Authors: Young Joo Shin, Kyu Hyung Park, Jeong-min Hwang, Won Ryang Wee, Jin Hak Lee
    Abstract:

    Purpose To investigate the efficacy of a novel computer-controlled Color test for the differentiation of congenital and acquired Color Vision deficiency. Design Observational cross-sectional study. Participants Thirty-one patients with congenital Color Vision deficiency and 134 patients with acquired Color Vision deficiency with a Snellen visual acuity better than 20/30 underwent an ophthalmologic examination including the Ishihara Color test, Hardy-Rand-Rittler test, Nagel anomaloscopy, and the Seohan computerized hue test between June, 2003, and January, 2004. Methods To investigate the type of Color Vision Defect, a graph of the Seohan computerized hue test was divided into 4 quadrants and error scores in each quadrant were summated. The ratio between the sums of error scores of quadrants I and III (Q1+Q3) and those of quadrants II and IV (Q2+Q4) was calculated. Main Outcome Measures Error scores and ratio in quadrant analysis of the Seohan computerized hue test. Results The Seohan computerized hue test showed that the sum of Q2+Q4 was significantly higher than the sum of Q1+Q3 in congenital Color Vision deficiency ( P t test) and that the sum of Q2+Q4 was significantly lower than the sum of Q1+Q3 in acquired Color Vision deficiency ( P t test). In terms of discriminating congenital and acquired Color Vision deficiency, the ratio in quadrant analysis had 93.3% sensitivity and 98.5% specificity with a reference value of 1.5 by the Seohan computerized hue test (95% confidence interval). Conclusions The quadrant analysis and ratio of (Q2+Q4)/(Q1+Q3) using the Seohan computerized hue test effectively differentiated congenital and acquired Color Vision deficiency.

  • efficacy of the computer program to compensate Color Vision deficiency using seohan computerized 85 hue test
    Journal of The Korean Ophthalmological Society, 2006
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, Seung Ji Yang
    Abstract:

    Purpose: to study the utility of a program which diagnoses and compensates for Color Defects on computer monitors according to the severity and type of Color Vision deficiency (CVD). Methods: Twenty-eight patients with congenital CVD completed Seohan computerized hue test, Color compensated Seohan computerized hue test and questionnaire for preference of Color compensated images. The relation between results of the Seohan computerized hue test and the degrees of Color compensation was investigated. HRR test and Nagel anomaloscope were used for determining the severity and type of CVD. Results: In applying the Color compensation program, the total error score (TES) of the Seohan computerized hue test was significantly reduced. In cases of milder Color Vision Defect, the TES of the Color compensated Seohan computerized hue test was reduced at lower Color compensations, while it was reduced at higher Color compensations in cases of more severe Color Vision Defect. In the Color compensation of images, patients with milder Color Vision Defects preferred images with lower Color compensation and patients with more severe Color Vision Defect preferred images with higher Color compensation. Conclusions: The Color compensation program for CVD effectively reduced the TES of Seohan computerized hue tests and improved the recognition of Colors. This suggests that the program can be helpful to actual life in patients with CVD.

  • the discriminatiuon between congenital and acquired Color Vision Defects by computerized Color Vision test
    Journal of The Korean Ophthalmological Society, 2005
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, In Bum Lee, Sang Yul Choi, Kyu Hyoung Park, Min Seoup Kim, Jeoung Min Hwang, Jae Hee Choi
    Abstract:

    Purpose: To investigate the characteristics of congenital and acquired Color Vision Defects with Seohan computerized hue test and SNU (Seoul National University) computerized Color test and to help to discriminate between congenital and acquired Color Vision Defect Methods: from June 2003 to January 2004, patient with congenital and acquired Color Vision Defect and visual acuities more than 20/30 underwent Seohan computerized hue and SNU computerized Color tests. Their results were compared with each other. Quadrant analysis and RQ calculation were done. Results: On Seohan computerized hue and SNU computerized Color tests, congenital Color Vision Defects showed mainly red-green Color Vision Defects (p

  • Color Vision Defect in diabetic retinopathy by snu computerized Color test
    Journal of The Korean Ophthalmological Society, 2005
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, In Bum Lee, Sang Yul Choi, Kyu Hyoung Park, Min Seoup Kim, Jeoung Min Hwang, Meena Lee, Seoungmin Joo
    Abstract:

    Purpose: To investigate the Color Vision Defect in diabetic patients using the SNU computerized Color test (SCCT). Methods: From May to September 2003, diabetic patients with visual acuity 0.6 or better underwent various examinations including biomicroscopy, fundus photography, Ishihara Color test, Hardy‐Rand‐Rittler (HRR) test, Seohan computerized hue test (SCHT), and SNU computerized Color test. The SCCT was developed by using the Matlab 6.0 program. Results: A total of 160 eyes of 82 diabetic patients were included. Thirty‐two patients had no diabetic retinopathy, 19 had mild nonproliferative diabetic retinopathy (NPDR), 12 had moderate NPDR, 12 had severe NPDR, and 7 had proliferative diabetic retinopathy (PDR). In the all diabetic patients, the average total error score (TES) of SCHT was 189 and that of SCCT was 8.5; in patients without diabetic retinopathy, the scores were 125 and 3.64; in patients with mild NPDR, 185 and 8.16; in patients with moderate NPDR, 209 and 11.1; in patients with severe NPDR, 288 and 15.6 ; and in patients with PDR, 324 and 17.6 respectively. On the HRR test, patients without diabetic retinopathy had 1 tritan Defect; those with mild NPDR 2 tritan, 2 protan, and 2 deutan Defects : those with moderate NPDR, no Color Defects ; and those with severe NPDR, 2 tritan, and 2 protan Defects, and 1 deutan Defect. Conclusions: In diabetic patients, TES of SCHT and SCCT was higher according to the severity of diabetic retinopathy. SCHT and SCCT were more useful than HRR test.

Jeong-min Hwang - One of the best experts on this subject based on the ideXlab platform.

  • validity of the worth 4 dot test in patients with red green Color Vision Defect
    Optometry and Vision Science, 2017
    Co-Authors: Eunoo Bak, Hee Kyung Yang, Jeong-min Hwang
    Abstract:

    ABSTRACTPurposeThe Worth four dot test uses red and green glasses for binocular dissociation, and although it has been believed that patients with red-green Color Vision Defects cannot accurately perform the Worth four dot test, this has not been validated. Therefore, the purpose of this study was t

  • a new Color Vision test to differentiate congenital and acquired Color Vision Defects
    Ophthalmology, 2007
    Co-Authors: Young Joo Shin, Kyu Hyung Park, Jeong-min Hwang, Won Ryang Wee, Jin Hak Lee
    Abstract:

    Purpose To investigate the efficacy of a novel computer-controlled Color test for the differentiation of congenital and acquired Color Vision deficiency. Design Observational cross-sectional study. Participants Thirty-one patients with congenital Color Vision deficiency and 134 patients with acquired Color Vision deficiency with a Snellen visual acuity better than 20/30 underwent an ophthalmologic examination including the Ishihara Color test, Hardy-Rand-Rittler test, Nagel anomaloscopy, and the Seohan computerized hue test between June, 2003, and January, 2004. Methods To investigate the type of Color Vision Defect, a graph of the Seohan computerized hue test was divided into 4 quadrants and error scores in each quadrant were summated. The ratio between the sums of error scores of quadrants I and III (Q1+Q3) and those of quadrants II and IV (Q2+Q4) was calculated. Main Outcome Measures Error scores and ratio in quadrant analysis of the Seohan computerized hue test. Results The Seohan computerized hue test showed that the sum of Q2+Q4 was significantly higher than the sum of Q1+Q3 in congenital Color Vision deficiency ( P t test) and that the sum of Q2+Q4 was significantly lower than the sum of Q1+Q3 in acquired Color Vision deficiency ( P t test). In terms of discriminating congenital and acquired Color Vision deficiency, the ratio in quadrant analysis had 93.3% sensitivity and 98.5% specificity with a reference value of 1.5 by the Seohan computerized hue test (95% confidence interval). Conclusions The quadrant analysis and ratio of (Q2+Q4)/(Q1+Q3) using the Seohan computerized hue test effectively differentiated congenital and acquired Color Vision deficiency.

Won Ryang Wee - One of the best experts on this subject based on the ideXlab platform.

  • a new Color Vision test to differentiate congenital and acquired Color Vision Defects
    Ophthalmology, 2007
    Co-Authors: Young Joo Shin, Kyu Hyung Park, Jeong-min Hwang, Won Ryang Wee, Jin Hak Lee
    Abstract:

    Purpose To investigate the efficacy of a novel computer-controlled Color test for the differentiation of congenital and acquired Color Vision deficiency. Design Observational cross-sectional study. Participants Thirty-one patients with congenital Color Vision deficiency and 134 patients with acquired Color Vision deficiency with a Snellen visual acuity better than 20/30 underwent an ophthalmologic examination including the Ishihara Color test, Hardy-Rand-Rittler test, Nagel anomaloscopy, and the Seohan computerized hue test between June, 2003, and January, 2004. Methods To investigate the type of Color Vision Defect, a graph of the Seohan computerized hue test was divided into 4 quadrants and error scores in each quadrant were summated. The ratio between the sums of error scores of quadrants I and III (Q1+Q3) and those of quadrants II and IV (Q2+Q4) was calculated. Main Outcome Measures Error scores and ratio in quadrant analysis of the Seohan computerized hue test. Results The Seohan computerized hue test showed that the sum of Q2+Q4 was significantly higher than the sum of Q1+Q3 in congenital Color Vision deficiency ( P t test) and that the sum of Q2+Q4 was significantly lower than the sum of Q1+Q3 in acquired Color Vision deficiency ( P t test). In terms of discriminating congenital and acquired Color Vision deficiency, the ratio in quadrant analysis had 93.3% sensitivity and 98.5% specificity with a reference value of 1.5 by the Seohan computerized hue test (95% confidence interval). Conclusions The quadrant analysis and ratio of (Q2+Q4)/(Q1+Q3) using the Seohan computerized hue test effectively differentiated congenital and acquired Color Vision deficiency.

  • efficacy of the computer program to compensate Color Vision deficiency using seohan computerized 85 hue test
    Journal of The Korean Ophthalmological Society, 2006
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, Seung Ji Yang
    Abstract:

    Purpose: to study the utility of a program which diagnoses and compensates for Color Defects on computer monitors according to the severity and type of Color Vision deficiency (CVD). Methods: Twenty-eight patients with congenital CVD completed Seohan computerized hue test, Color compensated Seohan computerized hue test and questionnaire for preference of Color compensated images. The relation between results of the Seohan computerized hue test and the degrees of Color compensation was investigated. HRR test and Nagel anomaloscope were used for determining the severity and type of CVD. Results: In applying the Color compensation program, the total error score (TES) of the Seohan computerized hue test was significantly reduced. In cases of milder Color Vision Defect, the TES of the Color compensated Seohan computerized hue test was reduced at lower Color compensations, while it was reduced at higher Color compensations in cases of more severe Color Vision Defect. In the Color compensation of images, patients with milder Color Vision Defects preferred images with lower Color compensation and patients with more severe Color Vision Defect preferred images with higher Color compensation. Conclusions: The Color compensation program for CVD effectively reduced the TES of Seohan computerized hue tests and improved the recognition of Colors. This suggests that the program can be helpful to actual life in patients with CVD.

  • the discriminatiuon between congenital and acquired Color Vision Defects by computerized Color Vision test
    Journal of The Korean Ophthalmological Society, 2005
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, In Bum Lee, Sang Yul Choi, Kyu Hyoung Park, Min Seoup Kim, Jeoung Min Hwang, Jae Hee Choi
    Abstract:

    Purpose: To investigate the characteristics of congenital and acquired Color Vision Defects with Seohan computerized hue test and SNU (Seoul National University) computerized Color test and to help to discriminate between congenital and acquired Color Vision Defect Methods: from June 2003 to January 2004, patient with congenital and acquired Color Vision Defect and visual acuities more than 20/30 underwent Seohan computerized hue and SNU computerized Color tests. Their results were compared with each other. Quadrant analysis and RQ calculation were done. Results: On Seohan computerized hue and SNU computerized Color tests, congenital Color Vision Defects showed mainly red-green Color Vision Defects (p

  • Color Vision Defect in diabetic retinopathy by snu computerized Color test
    Journal of The Korean Ophthalmological Society, 2005
    Co-Authors: Young Joo Shin, Won Ryang Wee, Jin Hak Lee, In Bum Lee, Sang Yul Choi, Kyu Hyoung Park, Min Seoup Kim, Jeoung Min Hwang, Meena Lee, Seoungmin Joo
    Abstract:

    Purpose: To investigate the Color Vision Defect in diabetic patients using the SNU computerized Color test (SCCT). Methods: From May to September 2003, diabetic patients with visual acuity 0.6 or better underwent various examinations including biomicroscopy, fundus photography, Ishihara Color test, Hardy‐Rand‐Rittler (HRR) test, Seohan computerized hue test (SCHT), and SNU computerized Color test. The SCCT was developed by using the Matlab 6.0 program. Results: A total of 160 eyes of 82 diabetic patients were included. Thirty‐two patients had no diabetic retinopathy, 19 had mild nonproliferative diabetic retinopathy (NPDR), 12 had moderate NPDR, 12 had severe NPDR, and 7 had proliferative diabetic retinopathy (PDR). In the all diabetic patients, the average total error score (TES) of SCHT was 189 and that of SCCT was 8.5; in patients without diabetic retinopathy, the scores were 125 and 3.64; in patients with mild NPDR, 185 and 8.16; in patients with moderate NPDR, 209 and 11.1; in patients with severe NPDR, 288 and 15.6 ; and in patients with PDR, 324 and 17.6 respectively. On the HRR test, patients without diabetic retinopathy had 1 tritan Defect; those with mild NPDR 2 tritan, 2 protan, and 2 deutan Defects : those with moderate NPDR, no Color Defects ; and those with severe NPDR, 2 tritan, and 2 protan Defects, and 1 deutan Defect. Conclusions: In diabetic patients, TES of SCHT and SCCT was higher according to the severity of diabetic retinopathy. SCHT and SCCT were more useful than HRR test.