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P Varalakshmi - One of the best experts on this subject based on the ideXlab platform.
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suppressive effect of withania somnifera root powder on experimental gouty arthritis an in vivo and in vitro study
Chemico-Biological Interactions, 2006Co-Authors: Mahaboobkhan Rasool, P VaralakshmiAbstract:The effect of Withania somnifera L. Dunal root powder on paw volume and serum lysosomal enzyme activities was investigated in monosodium urate crystal-induced rats. The levels of beta-glucuronidase and lactate dehydrogenase were also measured in monosodium urate crystal incubated polymorphonuclear leucocytes (PMNL). A significant increase in the level of paw volume and serum lysosomal enzymes was observed in monosodium urate crystal-induced rats. The increased beta-glucuronidase and lactate dehydrogenase level were observed in untreated monosodium urate crystal incubated polymorphonuclear leucocytes. On treatment with the W. somnifera root powder (500/1000 mg/kg body weight), the above changes were reverted back to near normal levels. W. somnifera also showed potent analgesic and antipyretic effect with the absence of gastric damage at different dose levels in experimental rats. For Comparison Purpose, non-steroidal anti-inflammatory drug (NSAID) indomethacin was used as a standard. These results provide evidence for the suppressive effect of W. somnifera root powder by retarding amplification and propagation of the inflammatory response without causing any gastric damage.
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suppressive effect of withania somnifera root powder on experimental gouty arthritis an in vivo and in vitro study
Chemico-Biological Interactions, 2006Co-Authors: Mahaboobkhan Rasool, P VaralakshmiAbstract:The effect of Withania somnifera L. Dunal root powder on paw volume and serum lysosomal enzyme activities was investigated in monosodium urate crystal-induced rats. The levels of β-glucuronidase and lactate dehydrogenase were also measured in monosodium urate crystal incubated polymorphonuclear leucocytes (PMNL). A significant increase in the level of paw volume and serum lysosomal enzymes was observed in monosodium urate crystal-induced rats. The increased β-glucuronidase and lactate dehydrogenase level were observed in untreated monosodium urate crystal incubated polymorphonuclear leucocytes. On treatment with the W. somnifera root powder (500/1000 mg/kg body weight), the above changes were reverted back to near normal levels. W. somnifera also showed potent analgesic and antipyretic effect with the absence of gastric damage at different dose levels in experimental rats. For Comparison Purpose, non-steroidal anti-inflammatory drug (NSAID) indomethacin was used as a standard. These results provide evidence for the suppressive effect of W. somnifera root powder by retarding amplification and propagation of the inflammatory response without causing any gastric damage.
Mahaboobkhan Rasool - One of the best experts on this subject based on the ideXlab platform.
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suppressive effect of withania somnifera root powder on experimental gouty arthritis an in vivo and in vitro study
Chemico-Biological Interactions, 2006Co-Authors: Mahaboobkhan Rasool, P VaralakshmiAbstract:The effect of Withania somnifera L. Dunal root powder on paw volume and serum lysosomal enzyme activities was investigated in monosodium urate crystal-induced rats. The levels of beta-glucuronidase and lactate dehydrogenase were also measured in monosodium urate crystal incubated polymorphonuclear leucocytes (PMNL). A significant increase in the level of paw volume and serum lysosomal enzymes was observed in monosodium urate crystal-induced rats. The increased beta-glucuronidase and lactate dehydrogenase level were observed in untreated monosodium urate crystal incubated polymorphonuclear leucocytes. On treatment with the W. somnifera root powder (500/1000 mg/kg body weight), the above changes were reverted back to near normal levels. W. somnifera also showed potent analgesic and antipyretic effect with the absence of gastric damage at different dose levels in experimental rats. For Comparison Purpose, non-steroidal anti-inflammatory drug (NSAID) indomethacin was used as a standard. These results provide evidence for the suppressive effect of W. somnifera root powder by retarding amplification and propagation of the inflammatory response without causing any gastric damage.
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suppressive effect of withania somnifera root powder on experimental gouty arthritis an in vivo and in vitro study
Chemico-Biological Interactions, 2006Co-Authors: Mahaboobkhan Rasool, P VaralakshmiAbstract:The effect of Withania somnifera L. Dunal root powder on paw volume and serum lysosomal enzyme activities was investigated in monosodium urate crystal-induced rats. The levels of β-glucuronidase and lactate dehydrogenase were also measured in monosodium urate crystal incubated polymorphonuclear leucocytes (PMNL). A significant increase in the level of paw volume and serum lysosomal enzymes was observed in monosodium urate crystal-induced rats. The increased β-glucuronidase and lactate dehydrogenase level were observed in untreated monosodium urate crystal incubated polymorphonuclear leucocytes. On treatment with the W. somnifera root powder (500/1000 mg/kg body weight), the above changes were reverted back to near normal levels. W. somnifera also showed potent analgesic and antipyretic effect with the absence of gastric damage at different dose levels in experimental rats. For Comparison Purpose, non-steroidal anti-inflammatory drug (NSAID) indomethacin was used as a standard. These results provide evidence for the suppressive effect of W. somnifera root powder by retarding amplification and propagation of the inflammatory response without causing any gastric damage.
Azhar Abu Bakar - One of the best experts on this subject based on the ideXlab platform.
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woven hybrid composites tensile and flexural properties of oil palm woven jute fibres based epoxy composites
Materials Science and Engineering A-structural Materials Properties Microstructure and Processing, 2011Co-Authors: Mohammad Jawaid, H Abdul P S Khalil, Azhar Abu BakarAbstract:Abstract In this research, tensile and flexural performance of tri layer oil palm empty fruit bunches (EFB)/woven jute (Jw) fibre reinforced epoxy hybrid composites subjected to layering pattern has been experimentally investigated. Sandwich composites were fabricated by hand lay-up technique in a mould and cured with 105 °C temperatures for 1 h by using hot press. Pure EFB and woven jute composites were also fabricate for Comparison Purpose. Results showed that tensile and flexural properties of pure EFB composite can be improved by hybridization with woven jute fibre as extreme woven jute fibre mat. It was found that tensile and flexural properties of hybrid composite is higher than that of EFB composite but less than woven jute composite. Statistical analysis of composites done by ANOVA-one way, it showed significant differences between the results obtained. The fracture surface morphology of the tensile samples of the hybrid composites was performed by using scanning electron microscopy.
Maznah Mat Kasim - One of the best experts on this subject based on the ideXlab platform.
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an unsupervised technique to estimate λ 0 fuzzy measure values and its application to multi criteria decision making
Conference on Industrial Electronics and Applications, 2020Co-Authors: Anath Rau Krishnan, Rizal Hamid, Maznah Mat KasimAbstract:The use of Choquet integral as an aggregation operator in multi-criteria decision-making problems requires the prior estimation of fuzzy measure values. λ0 -measure is one form of fuzzy measure which was introduced to reduce the usual computational complexity associated with the estimation of fuzzy measure values. However, the existing techniques to estimate λ0 -measure require some amount of initial data from the decision-makers. This paper, therefore, aimed at proposing a completely unsupervised estimation technique, where the λ0- measure values are directly derived based on the available decision matrix, without the need for any initial data from the decision-makers. The technique was developed by incorporating the CRITIC method into the original λ0 - measure estimation technique. The usage of the proposed technique was illustrated based on a university course evaluation problem. The same problem was also solved with a conventional additive operator for the Comparison Purpose.
Jameel Ahmed Baig - One of the best experts on this subject based on the ideXlab platform.
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essential trace elemental levels zinc iron and copper in the biological samples of smoker referent and pulmonary tuberculosis patients
Toxicology reports, 2019Co-Authors: Palwasha Nizamani, Hassan Imran Afridi, Tasneem Gul Kazi, Farah Naz Talpur, Jameel Ahmed BaigAbstract:Abstract Tuberculosis is one of the major causes of illnesses and deaths throughout world particularly in Asia. Smoking is linked with tuberculosis recurrence and its mortality and may influence bacteriological conversion, clinical symptoms and treatment outcome. The aim of current study was to estimate association among essential trace elements {zinc (Zn), iron (Fe) and copper (Cu)} in human biological samples particularly blood, serum, scalp hair, saliva, sputum, and nasal fluid of smoking and nonsmoking pulmonary tuberculosis patients (n = 165, age ranged 16–35 years) residents of Hyderabad, Pakistan. The biological samples of age matched healthy controls were chosen as referents of both genders (n = 171) for the Comparison Purpose. The human biological samples were wet digested in microwave oven by 65 % HNO3 and 30 % H2O2 with (2:1) ratio. The concentrations of elements in acid digested samples were determined by atomic absorption spectrometry. The average zinc and iron concentration was lower, while level of copper was higher in the biological samples of pulmonary Tuberculosis patients as compared to referent subjects (p
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evaluation of arsenic cobalt copper and manganese in biological samples of steel mill workers by electrothermal atomic absorption spectrometry
Toxicology and Industrial Health, 2009Co-Authors: Hassan Imran Afridi, Tasneem Gul Kazi, Mohammad Balal Arain, Naveed Kazi, M K Jamali, Ghulam Abbas Kandhro, Afzal Shah, Jameel Ahmed BaigAbstract:The determination of trace and toxic elements in biological samples (blood, urine and scalp hair samples) of human beings is an important clinical test. The aim of our present study was to determine the concentration of arsenic (As), copper (Cu), cobalt (Co) and manganese (Mn), in biological samples of male production workers (PW) and quality control workers (QW) of steel mill, with aged 25–55 years, to assess the possible influence of environmental exposure. For Comparison Purpose, the same biological samples of unexposed healthy males of same age group were collected as control subjects. The determination of all elements in biological samples was carried out by electrothermal atomic absorption spectrometry, prior to microwave assisted acid digestion. The accuracy of the As, Cu, Co and Mn measurements was tested by simultaneously analyzing certified reference materials (CRMs) and for comparative Purposes conventional wet acid digestion method was used on the same CRMs. No significant differences were obs...