The Experts below are selected from a list of 403737 Experts worldwide ranked by ideXlab platform

Pauli Puolakkainen - One of the best experts on this subject based on the ideXlab platform.

Bruce H Hasegawa - One of the best experts on this subject based on the ideXlab platform.

  • technological development and advances in single photon emission Computed Tomography Computed Tomography
    Seminars in Nuclear Medicine, 2008
    Co-Authors: Youngho Seo, Carina Mari, Bruce H Hasegawa
    Abstract:

    Single-photon emission Computed Tomography/Computed Tomography (SPECT/CT) has emerged during the past decade as a means of correlating anatomical information from CT with functional information from SPECT. The integration of SPECT and CT in a single imaging device facilitates anatomical localization of the radiopharmaceutical to differentiate physiological uptake from that associated with disease and patient-specific attenuation correction to improve the visual quality and quantitative accuracy of the SPECT image. The first clinically available SPECT/CT systems performed emission-transmission imaging using a dual-headed SPECT camera and a low-power x-ray CT subsystem. Newer SPECT/CT systems are available with high-power CT subsystems suitable for detailed anatomical diagnosis, including CT coronary angiography and coronary calcification that can be correlated with myocardial perfusion measurements. The high-performance CT capabilities also offer the potential to improve compensation of partial volume errors for more accurate quantitation of radionuclide measurement of myocardial blood flow and other physiological processes and for radiation dosimetry for radionuclide therapy. In addition, new SPECT technologies are being developed that significantly improve the detection efficiency and spatial resolution for radionuclide imaging of small organs including the heart, brain, and breast, and therefore may provide new capabilities for SPECT/CT imaging in these important clinical applications.

Stephan Achenbach - One of the best experts on this subject based on the ideXlab platform.

  • Computed Tomography imaging in the context of transcatheter aortic valve implantation tavi transcatheter aortic valve replacement tavr an expert consensus document of the society of cardiovascular Computed Tomography
    Jacc-cardiovascular Imaging, 2019
    Co-Authors: Philipp Blanke, Stephan Achenbach, Jonathan R Weirmccall, Victoria Delgado, Jorg Hausleiter, Hasan Jilaihawi, Mohamed Marwan, Bjarne L Norgaard, Niccolo Piazza, Paul Schoenhagen
    Abstract:

    Since the publication of the first expert consensus document on Computed Tomography imaging before transcatheter aortic valve implantation (TAVI)/transcatheter aortic valve replacement (TAVR) by the Society of Cardiovascular Computed Tomography (SCCT) in 2012 [(1)][1], there has been tremendous

  • standardized medical terminology for cardiac Computed Tomography a report of the society of cardiovascular Computed Tomography
    Journal of Cardiovascular Computed Tomography, 2011
    Co-Authors: Wm Guy Weigold, Stephan Achenbach, Suhny Abbara, Armin Arbabzadeh, Daniel S Berman, Jeffrey J Carr, Ricardo C Cury, Sandra S Halliburton, Cynthia H Mccollough, Allen J Taylor
    Abstract:

    Abstract Since the emergence of cardiac Computed Tomography (CT) at the turn of the 21st century, there has been an exponential growth in research and clinical development of the technique, with contributions from investigators and clinicians from varied backgrounds: physics and engineering, informatics, cardiology, and radiology. However, terminology for the field is not unified. As a consequence, there are multiple abbreviations for some terms, multiple terms for some concepts, and some concepts that lack clear definitions and/or usage. In an effort to aid the work of all those who seek to contribute to the literature, clinical practice, and investigation of the field, the Society of Cardiovascular Computed Tomography sets forth a standard set of medical terms commonly used in clinical and investigative practice of cardiac CT.

  • Computed Tomography coronary angiography
    Journal of the American College of Cardiology, 2006
    Co-Authors: Stephan Achenbach
    Abstract:

    Recent developments in Computed Tomography technology have made imaging of the coronary arteries possible. All the same, the rapid motion and small dimensions of the coronary vessels make coronary Computed Tomography angiography (coronary CTA) challenging. With the last generations of 16- and 64-slice Computed Tomography and adequate patient preparation (which includes lowering of the heart rate), rates of sensitivity ranging from 83% to 99% and specificity between 93% and 98% have been reported for the detection of coronary artery stenoses in comparison with invasive coronary angiography. The high negative predictive value (95% to 100%) found in these studies suggests that coronary CTA may be a useful diagnostic technique to rule out the presence of coronary stenoses in selected patients, especially those with a rather low pretest likelihood of disease. Imaging of coronary artery bypass grafts is reliable, but clinical applications can be hampered by difficulties in assessing the native coronary arteries in patients after undergoing bypass because of their often-severe calcification. The detection of in-stent restenosis is made difficult by artifacts caused by metal, especially in smaller stents. Finally, initial reports that coronary CTA allows the detection and, to a certain extent, also the characterization and quantification of noncalcified coronary arteriosclerotic plaque are interesting, but they currently do not provide sufficient data to support clinical applications in the context of risk stratification.

  • noninvasive coronary angiography by magnetic resonance imaging electron beam Computed Tomography and multislice Computed Tomography
    American Journal of Cardiology, 2001
    Co-Authors: Stephan Achenbach, Dieter Ropers, Matthias Regenfus, Karsten Pohle, T Giesler, Werner Moshage, Werner G Daniel
    Abstract:

    In recent years, several techniques for noninvasive imaging of the coronary artery lumen (noninvasive coronary angiography) have been developed. These techniques include magnetic resonance imaging, electron-beam Computed Tomography, and, most recently, multislice Computed Tomography. Each of these techniques has specific advantages and disadvantages. Currently, EBCT seems to permit the most robust coronary artery imaging. In the future, imaging modalities will have to be further improved and validated in order to define specific areas for potential clinical applications.

Saima Mushtaq - One of the best experts on this subject based on the ideXlab platform.

  • dynamic stress Computed Tomography perfusion with a whole heart coverage scanner in addition to coronary Computed Tomography angiography and fractional flow reserve Computed Tomography derived
    Jacc-cardiovascular Imaging, 2019
    Co-Authors: Gianluca Pontone, Andrea Baggiano, Daniele Andreini, Andrea Igoren Guaricci, Marco Guglielmo, Giuseppe Muscogiuri, Laura Fusini, Margherita Soldi, Alberico Del Torto, Saima Mushtaq
    Abstract:

    Abstract Objectives The aims of the study were to test the diagnostic accuracy of integrated evaluation of dynamic myocardial Computed Tomography perfusion (CTP) on top of coronary Computed Tomography angiography (cCTA) plus fractional flow reserve Computed Tomography derived (FFRCT) by using a whole-heart coverage Computed Tomography (CT) scanner as compared with clinically indicated invasive coronary angiography (ICA) and invasive fractional flow reserve (FFR). Background Recently, new techniques such as dynamic stress Computed Tomography perfusion (stress-CTP) emerged as potential strategies to combine anatomical and functional evaluation in a one-shot scan. However, previous experiences with this technique were associated with high radiation exposure. Methods Eighty-five consecutive symptomatic patients scheduled for ICA were prospectively enrolled. All patients underwent rest cCTA followed by stress dynamic CTP with a whole-heart coverage CT scanner (Revolution CT, GE Healthcare, Milwaukee, Wisconsin). FFRCT was also measured by using the rest cCTA dataset. The diagnostic accuracy to detect functionally significant coronary artery disease (CAD) in a vessel-based model of cCTA alone, cCTA+FFRCT, cCTA+CTP, or cCTA+FFRCT+CTP were assessed and compared by using ICA and invasive FFR as reference. The overall effective dose of dynamic CTP was also measured. Results The prevalence of obstructive CAD and functionally significant CAD was 77% and 57%, respectively. The sensitivity and specificity of cCTA alone, cCTA+FFRCT, and cCTA+CTP were 83% and 66%, 86% and 75%, and 73% and 86%, respectively. Both the addition of FFRCT and CTP improves the area under the curve (AUC: 0.876 and 0.878, respectively) as compared with cCTA alone (0.826; p  Conclusions The addition of dynamic stress CTP on top of cCTA and FFRCT provides additional diagnostic accuracy with acceptable radiation exposure.

Diwakar Jain - One of the best experts on this subject based on the ideXlab platform.

  • single photon emission Computed Tomography
    Journal of Nuclear Cardiology, 2010
    Co-Authors: Thomas A Holly, Edward P. Ficaro, Brian G Abbott, Mouaz H Almallah, Dennis A Calnon, Mylan C Cohen, Frank P Difilippo, Michael R Freeman, Robert C Hendel, Diwakar Jain
    Abstract:

    Publisher Summary This chapter discusses single photon emission Computed Tomography. The development of single photon emission Computed Tomography (SPECT) put a powerful physiologic imaging technology in the hands of physicians and researchers. SPECT is neither as expensive nor as complex as positron emission Tomography (PET) and can be used for many of the same purposes. Cone beam or neurofocal collimation is the most advanced collimator adaptation of the rotating gamma camera to neuro-SPECT. With a two-axis converging collimator rotating about the patient's head, the sensitivity to radiation can be two to four times that of parallel or slant collimators. Resolution approaches 10 mm FWHM. A difficult problem in SPECT imaging is correcting for scatter. The energy window used for photon discrimination includes some off-axis, Comptom-scattered radiation that is back-projected as noise into the reconstructed image along with legitimate, on-axis photons. The deeper inside any scattering material the target image is, the worse the effect is on image resolution. Several schemes are used to compensate for this effect. Labeled-antibody SPECT—with implications for beta and gamma emitter therapy in some cases—is a wide-open field limited only by the nonspecific binding of some antibody preparations. With continuing investigation, more specific agents may become available.