The Experts below are selected from a list of 39615 Experts worldwide ranked by ideXlab platform
Jean-luc Van Laethem - One of the best experts on this subject based on the ideXlab platform.
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Adjuvant gemcitabine and concurrent Continuous Radiation (45 Gy) for resected pancreatic head carcinoma: a multicenter Belgian Phase II study.
International journal of radiation oncology biology physics, 2005Co-Authors: Anne Demols, Marc Peeters, Marc Polus, Pierre Honore, Tom Boterberg, M.t. Closon, Paul Van Houtte, Jean Closset, Jean-luc Van LaethemAbstract:Purpose: To evaluate the feasibility and tolerance of a postoperative course of gemcitabine (GEM) combined with Continuous Radiation after curative resection of pancreatic adenocarcinoma. Methods and Materials: Thirty patients (median age, 61 years; performance status, 0 to 1) with Stage II and III curatively resected pancreatic head adenocarcinoma were included. Gemcitabine 1000 mg/m 2 (3 out of 4 weeks, two cycles) was given within 8 weeks of surgery and followed by GEM 300 mg/m 2 weekly combined with Continuous Radiation (45 Gy in 25 fractions, 1.8 Gy per fraction). Results: For GEM alone, all patients received the two courses with dose reductions in 14 of 30 patients (46%). All but 3 patients completed full chemoRadiation; 1 stopped Radiation because of subocclusion of a gastroenterostomy, and 2 did not start owing to disease progression. Reduction in GEM during Radiation was necessary in 12 of 30 patients (40%). No toxic death was noted; World Health Organization Grade 3/4 hematologic and nonhematologic toxicities were seen in 10 of 30 patients (33%) and 3 of 30 patients (10%), respectively. After a median follow-up of 19 months, no late toxicity was reported. Eleven patients died from progressive disease; median disease-free survival and overall survival were 14.5 and 19 months, respectively. Conclusion: This adjuvant combination is well tolerated and can be safely administered after curative surgery for pancreatic cancer. Further evaluation of this regimen is ongoing.
Susanne Hüttemeister - One of the best experts on this subject based on the ideXlab platform.
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Solutions for Chapter 10: Emission Mechanisms of Continuous Radiation
Astronomy and Astrophysics Library, 2018Co-Authors: Thomas L. Wilson, Susanne HüttemeisterAbstract:The angular diameter is θ = 0.1∕(1.46 × 106) = 6.84 × 10−8 radians = 2.4 × 10−4 arc min = 1.4 × 10−2 arc sec. The corresponding solid angle is Ω = 3.67 × 10−15 steradians. The flux is given by S = 2kTBΩ∕λ2 = 6.0 × 10−4 Jy. If a Gaussian brightness distribution is assumed instead (doubtful for an asteroid), the result is S = 2.65 TBθ[′]2∕λ[cm]2 = 8.65 × 10−4 Jy.
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Emission Mechanisms of Continuous Radiation
Astronomy and Astrophysics Library, 2013Co-Authors: Thomas L. Wilson, Kristen Rohlfs, Susanne HüttemeisterAbstract:In the early days of radio astronomy the receiver sensitivities restricted measurements to the few hundred megahertz range. At such relatively low frequencies the resolving power of the available radio telescopes was low. Initially only very few of the discrete sources could be identified with objects known from the optical region of the spectrum. Further investigations showed an increase in the number of sources with decreasing source flux density and gave the distribution of sources in the sky. It was then concluded that there are two different families of sources: galactic sources, concentrated towards the galactic plane and extragalactic sources distributed more or less uniformly in space. The unresolved, spatially Continuous Radiation belongs to the galactic component. In addition, there is the 2.7K thermal background Radiation which is cosmological in origin.
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Spectral Line Fundamentals
Astronomy and Astrophysics Library, 2013Co-Authors: Thomas L. Wilson, Kristen Rohlfs, Susanne HüttemeisterAbstract:In local thermodynamic equilibrium (LTE) the intensities of emitted and absorbed Radiation are not independent but are related by Kirchhoff’s law (1.14). This applies to both Continuous Radiation and line Radiation. The Einstein coefficients give a convenient means to describe the interaction of Radiation with matter by the emission and absorption of photons.
Anne Demols - One of the best experts on this subject based on the ideXlab platform.
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Adjuvant gemcitabine and concurrent Continuous Radiation (45 Gy) for resected pancreatic head carcinoma: a multicenter Belgian Phase II study.
International journal of radiation oncology biology physics, 2005Co-Authors: Anne Demols, Marc Peeters, Marc Polus, Pierre Honore, Tom Boterberg, M.t. Closon, Paul Van Houtte, Jean Closset, Jean-luc Van LaethemAbstract:Purpose: To evaluate the feasibility and tolerance of a postoperative course of gemcitabine (GEM) combined with Continuous Radiation after curative resection of pancreatic adenocarcinoma. Methods and Materials: Thirty patients (median age, 61 years; performance status, 0 to 1) with Stage II and III curatively resected pancreatic head adenocarcinoma were included. Gemcitabine 1000 mg/m 2 (3 out of 4 weeks, two cycles) was given within 8 weeks of surgery and followed by GEM 300 mg/m 2 weekly combined with Continuous Radiation (45 Gy in 25 fractions, 1.8 Gy per fraction). Results: For GEM alone, all patients received the two courses with dose reductions in 14 of 30 patients (46%). All but 3 patients completed full chemoRadiation; 1 stopped Radiation because of subocclusion of a gastroenterostomy, and 2 did not start owing to disease progression. Reduction in GEM during Radiation was necessary in 12 of 30 patients (40%). No toxic death was noted; World Health Organization Grade 3/4 hematologic and nonhematologic toxicities were seen in 10 of 30 patients (33%) and 3 of 30 patients (10%), respectively. After a median follow-up of 19 months, no late toxicity was reported. Eleven patients died from progressive disease; median disease-free survival and overall survival were 14.5 and 19 months, respectively. Conclusion: This adjuvant combination is well tolerated and can be safely administered after curative surgery for pancreatic cancer. Further evaluation of this regimen is ongoing.
C. Fleurier - One of the best experts on this subject based on the ideXlab platform.
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A Radiation source developed for broad band optical absorption spectroscopy measurements
Plasma Sources Science and Technology. ., 2003Co-Authors: Duke Hong, K Lan, G. Sandolache, E. Le Menn, Jean-marc Bauchire, C. FleurierAbstract:In order to investigate the post-arc period and the hot gas regions surrounding the electrical arc in circuit breakers, a broad band Radiation source has been developed to perform absorption spectroscopy measurements. The source consists of a Z-pinch electrical discharge in which the high temperature and the high density argon plasma obtained at maximum compression produces an extremely intense Continuous Radiation pulse of about 2 mus duration. The Radiation spectrum has been characterized both temporally and spectrally in order to determine the best operating conditions to produce an intense and Continuous Radiation spectrum. Absorption tests have been performed on the hot gas region of a low voltage rail gap circuit breaker. Absorption of copper atom resonance lines (Cu I 324.75 and Cu I 327.40 nm) is used to determine the copper atom density in the rear of the arc. In addition, absorption of the C/sub 2/ molecule Swan bands, (0, 0) and (1, 1), is used to determine roughly the concentration Of C/sub 2/ and also the kinetic temperature of the hot gas
Thomas L. Wilson - One of the best experts on this subject based on the ideXlab platform.
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Solutions for Chapter 10: Emission Mechanisms of Continuous Radiation
Astronomy and Astrophysics Library, 2018Co-Authors: Thomas L. Wilson, Susanne HüttemeisterAbstract:The angular diameter is θ = 0.1∕(1.46 × 106) = 6.84 × 10−8 radians = 2.4 × 10−4 arc min = 1.4 × 10−2 arc sec. The corresponding solid angle is Ω = 3.67 × 10−15 steradians. The flux is given by S = 2kTBΩ∕λ2 = 6.0 × 10−4 Jy. If a Gaussian brightness distribution is assumed instead (doubtful for an asteroid), the result is S = 2.65 TBθ[′]2∕λ[cm]2 = 8.65 × 10−4 Jy.
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Emission Mechanisms of Continuous Radiation
Astronomy and Astrophysics Library, 2013Co-Authors: Thomas L. Wilson, Kristen Rohlfs, Susanne HüttemeisterAbstract:In the early days of radio astronomy the receiver sensitivities restricted measurements to the few hundred megahertz range. At such relatively low frequencies the resolving power of the available radio telescopes was low. Initially only very few of the discrete sources could be identified with objects known from the optical region of the spectrum. Further investigations showed an increase in the number of sources with decreasing source flux density and gave the distribution of sources in the sky. It was then concluded that there are two different families of sources: galactic sources, concentrated towards the galactic plane and extragalactic sources distributed more or less uniformly in space. The unresolved, spatially Continuous Radiation belongs to the galactic component. In addition, there is the 2.7K thermal background Radiation which is cosmological in origin.
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Spectral Line Fundamentals
Astronomy and Astrophysics Library, 2013Co-Authors: Thomas L. Wilson, Kristen Rohlfs, Susanne HüttemeisterAbstract:In local thermodynamic equilibrium (LTE) the intensities of emitted and absorbed Radiation are not independent but are related by Kirchhoff’s law (1.14). This applies to both Continuous Radiation and line Radiation. The Einstein coefficients give a convenient means to describe the interaction of Radiation with matter by the emission and absorption of photons.