The Experts below are selected from a list of 167202 Experts worldwide ranked by ideXlab platform

Tetsuro Oshika - One of the best experts on this subject based on the ideXlab platform.

  • deterioration of Contrast Sensitivity in eyes with epiphora due to lacrimal passage obstruction
    PLOS ONE, 2020
    Co-Authors: Kuniharu Tasaki, Sujin Hoshi, Takahiro Hiraoka, Tetsuro Oshika
    Abstract:

    Purpose Epiphora causes deterioration in Contrast Sensitivity in some eye diseases. This study was conducted to investigate Contrast Sensitivity in eyes with epiphora caused by lacrimal passage obstruction. Methods This single-center, prospective case series enrolled 57 patients with unilateral lacrimal passage obstruction. The best-corrected visual acuity (BCVA), Contrast Sensitivity function, and lower tear meniscus of the affected and contralateral unaffected eyes were compared. The area under the log Contrast Sensitivity function (AULCSF) was calculated. Results The BCVA did not significantly differ between the affected and contralateral eyes, while the AULCSF was significantly lower in the affected eyes than that in the contralateral eyes (median 1.35, interquartile range 1.22–1.44 vs. median 1.36, interquartile range 1.28–1.46, P = 0.032). Lower tear meniscus parameters were significantly higher in the affected eyes than those in the contralateral eyes (P < 0.005). Conclusions The Contrast Sensitivity function is significantly diminished in eyes with epiphora caused by lacrimal passage obstruction.

  • Contrast Sensitivity function and ocular higher order wavefront aberrations in normal human eyes
    Ophthalmology, 2006
    Co-Authors: Tetsuro Oshika, Tadatoshi Tokunaga, Tomokazu Samejima, C Okamoto, Kazunori Miyata
    Abstract:

    Purpose To investigate the relation between Contrast Sensitivity function and ocular higher-order wavefront aberrations in normal human eyes. Study Design Prospective observational case series. Participants Three hundred seven eyes of 161 normal subjects, ranging in age from 15 to 60 years (30.9±8.0 [mean ± standard deviation]). Methods Ocular higher-order aberrations were measured for a 4-mm pupil using the Hartmann–Shack wavefront analyzer. The root-mean-square of the third- and fourth-order Zernike coefficients was used to represent comalike and spherical-like aberrations, respectively. We measured Contrast Sensitivity, low-Contrast visual acuity (VA), and letter Contrast Sensitivity. From the Contrast Sensitivity data, the area under the log Contrast Sensitivity function (AULCSF) was calculated. Pupil diameter in a photopic condition was recorded using a digital camera. Results Multiple linear regression analysis revealed that comalike aberration ( P = 0.002) was significantly associated with AULCSF, but spherical-like aberration ( P = 0.200), age ( P = 0.185), and photopic pupil diameter ( P =0.252) were not. Comalike aberration showed a significant correlation with low-Contrast VA ( P P = 0.293), age ( P = 0.266), and pupil diameter ( P = 0.756) did not. Comalike aberration was found to be significantly associated with letter Contrast Sensitivity ( P P =0.082), age ( P = 0.370), and pupil diameter ( P = 0.160) were not. Conclusions In normal human eyes, comalike aberration of the eye significantly influences Contrast Sensitivity function.

  • ocular higher order aberrations and Contrast Sensitivity after conventional laser in situ keratomileusis
    Investigative Ophthalmology & Visual Science, 2004
    Co-Authors: N Yamane, Kazunori Miyata, Tomokazu Samejima, Takahiro Hiraoka, Takahiro Kiuchi, Fumiki Okamoto, Yoko Hirohara, Toshifumi Mihashi, Tetsuro Oshika
    Abstract:

    PURPOSE. To investigate prospectively the relation between induced changes in higher-order aberrations of the eye and changes in Contrast Sensitivity by conventional laser in situ keratomileusis (LASIK) for myopia. METHODS. In 200 eyes of 110 consecutive patients (mean age, 32.7 8.4 years) undergoing LASIK, ocular aberrations and Contrast Sensitivity function were determined before and 1 month after surgery. The amount of myopic correction was 5.2 2.8 D (range, 1.0 –13.0). Ocular higher-order aberrations were measured for a 4-mm pupil using the Hartmann-Shack wavefront analyzer (KR-9000PW; Topcon, Tokyo, Japan). The root mean square (RMS) of the third- and fourth-order Zernike coefficients was used to represent coma- and spherical-like aberrations, respectively. Total higher-order aberrations were calculated as the RMS of the third- and fourth-order coefficients. Contrast Sensitivity and low-Contrast visual acuity were measured. From the Contrast Sensitivity data, the area under the log Contrast Sensitivity function (AULCSF) was calculated. RESULTS. LASIK significantly improved logMAR best corrected visual acuity (Wilcoxon signed-rank test, P 0.001), but significantly reduced AULCSF (P 0.001) and low-Contrast visual acuity (P 0.007). Total higher-order (P 0.001), coma-like (P 0.001), and spherical-like (P 0.001) aberrations were significantly increased after LASIK. The greater the amount of achieved myopia correction was, the more the changes in Contrast Sensitivity function and ocular higher-order aberrations were. The induced changes in AULCSF by LASIK showed significant correlations with changes in total higher-order (Pearson r 0.221, P 0.003), coma-like (r 0.205, P 0.006), and spherical-like (r 0.171, P 0.022) aberrations. The changes in logMAR low-Contrast visual acuity by surgery significantly correlated with changes in total higher-order (r 0.222, P 0.003), coma-like (r 0.201, P 0.007), and spherical-like (r 0.207, P 0.005) aberrations. CONCLUSIONS. Conventional LASIK significantly increases ocular higher-order aberrations, which compromise the postoperative Contrast Sensitivity function. (Invest Ophthalmol Vis Sci. 2004; 45:3986 –3990) DOI:10.1167/iovs.04-0629

Takahiro Hiraoka - One of the best experts on this subject based on the ideXlab platform.

  • Improvement in Contrast Sensitivity Function after Lacrimal Passage Intubation in Eyes with Epiphora.
    Journal of clinical medicine, 2020
    Co-Authors: Sujin Hoshi, Kuniharu Tasaki, Takahiro Hiraoka
    Abstract:

    This prospective case series aimed to investigate the Contrast Sensitivity function before and after lacrimal passage intubation (LPI) in eyes with epiphora due to lacrimal passage obstruction. We included 58 eyes of 51 patients who underwent LPI for lacrimal passage obstruction. The best-corrected visual acuity (BCVA), Contrast Sensitivity function, and lower tear meniscus were compared before LPI and one month after lacrimal duct stent removal. The area under the log Contrast Sensitivity function (AULCSF) was calculated for the analyses. Lower tear meniscus was assessed using anterior segment optical coherence tomography. The BCVA was comparable (p = 0.61) before and after LPI, while AULCSF increased significantly after treatment (before LPI: 1.29 ± 0.17, after LPI: 1.37 ± 0.14, p < 0.0001). Treatment resulted in a significant increase in Contrast Sensitivity at all spatial frequencies, 3–18 cycles/degree (p < 0.01 for 3, p < 0.01 for 6, p < 0.0005 for 12, p < 0.05 for 18 cycles/degree). The lower tear meniscus parameters improved significantly after treatment (p < 0.005); however, no correlation between the changes in the tear meniscus and those of the AULCSF was found. The Contrast Sensitivity significantly improved after LPI in eyes with epiphora due to lacrimal passage obstruction.

  • deterioration of Contrast Sensitivity in eyes with epiphora due to lacrimal passage obstruction
    PLOS ONE, 2020
    Co-Authors: Kuniharu Tasaki, Sujin Hoshi, Takahiro Hiraoka, Tetsuro Oshika
    Abstract:

    Purpose Epiphora causes deterioration in Contrast Sensitivity in some eye diseases. This study was conducted to investigate Contrast Sensitivity in eyes with epiphora caused by lacrimal passage obstruction. Methods This single-center, prospective case series enrolled 57 patients with unilateral lacrimal passage obstruction. The best-corrected visual acuity (BCVA), Contrast Sensitivity function, and lower tear meniscus of the affected and contralateral unaffected eyes were compared. The area under the log Contrast Sensitivity function (AULCSF) was calculated. Results The BCVA did not significantly differ between the affected and contralateral eyes, while the AULCSF was significantly lower in the affected eyes than that in the contralateral eyes (median 1.35, interquartile range 1.22–1.44 vs. median 1.36, interquartile range 1.28–1.46, P = 0.032). Lower tear meniscus parameters were significantly higher in the affected eyes than those in the contralateral eyes (P < 0.005). Conclusions The Contrast Sensitivity function is significantly diminished in eyes with epiphora caused by lacrimal passage obstruction.

  • Contrast Sensitivity function and ocular higher order aberrations following overnight orthokeratology
    Investigative Ophthalmology & Visual Science, 2007
    Co-Authors: Takahiro Hiraoka, C Okamoto, Yuko Ishii, Tetsuhiko Kakita
    Abstract:

    PURPOSE. To evaluate relationships among Contrast Sensitivity function, ocular higher-order aberration, and myopic correction in eyes undergoing overnight orthokeratology for myopia. METHODS. A prospective study was conducted in 46 eyes of 23 patients undergoing orthokeratology. Inclusion criteria were spherical equivalent refraction between - 1.00 and - 4.00 diopters (D), refractive astigmatism up to 1.00 D, and best-corrected visual acuity of 20/20 or better. Ocular higher-order aberrations and Contrast Sensitivity function were determined before and 3 months after initiation of the procedure. We measured three indices of Contrast Sensitivity function: Contrast Sensitivity, low-Contrast visual acuity, and letter Contrast Sensitivity with the CSV-1000 charts (Vector Vision Co., Greenville, OH). Area under the log Contrast Sensitivity function (AULCSF) was calculated from the Contrast Sensitivity data. RESULTS. Orthokeratology significantly improved logMAR uncorrected visual acuity (P < 0.0001; paired t-test) but significantly increased ocular higher-order aberrations (P < 0.0001) and decreased Contrast Sensitivity function, including AULCSF (P < 0.0001), low-Contrast visual acuity (P = 0.0025), and letter Contrast Sensitivity (P < 0.0001; Wilcoxon signed-rank test). The induced changes in AULCSF, low-Contrast visual acuity, and letter Contrast Sensitivity by orthokeratology showed significant correlation with changes in third-order (Pearson r = -0.430, P = 0.0026; r = 0.423, P = 0.0031; and Spearman r s = -0.351, P = 0.0186, respectively), fourth-order (r = -0.418, P = 0.0035; r = 0.425, P = 0.0029; and r s = - 0.566, P = 0.0001, respectively), and total higher-order (r = -0.460, P = 0.0011; r = 0.471, P = 0.0008; and r s = -0.434, P = 0.0036, respectively) aberrations. The induced changes in Contrast Sensitivity function and higher-order aberrations significantly correlated with the amount of myopic correction (P < 0.01). CONCLUSIONS. Orthokeratology significantly increases ocular higher-order aberrations and compromises Contrast Sensitivity function, depending on the amount of myopic correction.

  • ocular higher order aberrations and Contrast Sensitivity after conventional laser in situ keratomileusis
    Investigative Ophthalmology & Visual Science, 2004
    Co-Authors: N Yamane, Kazunori Miyata, Tomokazu Samejima, Takahiro Hiraoka, Takahiro Kiuchi, Fumiki Okamoto, Yoko Hirohara, Toshifumi Mihashi, Tetsuro Oshika
    Abstract:

    PURPOSE. To investigate prospectively the relation between induced changes in higher-order aberrations of the eye and changes in Contrast Sensitivity by conventional laser in situ keratomileusis (LASIK) for myopia. METHODS. In 200 eyes of 110 consecutive patients (mean age, 32.7 8.4 years) undergoing LASIK, ocular aberrations and Contrast Sensitivity function were determined before and 1 month after surgery. The amount of myopic correction was 5.2 2.8 D (range, 1.0 –13.0). Ocular higher-order aberrations were measured for a 4-mm pupil using the Hartmann-Shack wavefront analyzer (KR-9000PW; Topcon, Tokyo, Japan). The root mean square (RMS) of the third- and fourth-order Zernike coefficients was used to represent coma- and spherical-like aberrations, respectively. Total higher-order aberrations were calculated as the RMS of the third- and fourth-order coefficients. Contrast Sensitivity and low-Contrast visual acuity were measured. From the Contrast Sensitivity data, the area under the log Contrast Sensitivity function (AULCSF) was calculated. RESULTS. LASIK significantly improved logMAR best corrected visual acuity (Wilcoxon signed-rank test, P 0.001), but significantly reduced AULCSF (P 0.001) and low-Contrast visual acuity (P 0.007). Total higher-order (P 0.001), coma-like (P 0.001), and spherical-like (P 0.001) aberrations were significantly increased after LASIK. The greater the amount of achieved myopia correction was, the more the changes in Contrast Sensitivity function and ocular higher-order aberrations were. The induced changes in AULCSF by LASIK showed significant correlations with changes in total higher-order (Pearson r 0.221, P 0.003), coma-like (r 0.205, P 0.006), and spherical-like (r 0.171, P 0.022) aberrations. The changes in logMAR low-Contrast visual acuity by surgery significantly correlated with changes in total higher-order (r 0.222, P 0.003), coma-like (r 0.201, P 0.007), and spherical-like (r 0.207, P 0.005) aberrations. CONCLUSIONS. Conventional LASIK significantly increases ocular higher-order aberrations, which compromise the postoperative Contrast Sensitivity function. (Invest Ophthalmol Vis Sci. 2004; 45:3986 –3990) DOI:10.1167/iovs.04-0629

Robert Montesmico - One of the best experts on this subject based on the ideXlab platform.

  • comparison of Contrast Sensitivity and color discrimination after clear and yellow intraocular lens implantation
    Journal of Cataract and Refractive Surgery, 2005
    Co-Authors: Antonio Rodriguezgalietero, Robert Montesmico, Gonzalo Munoz, Cesar Albarrandiego
    Abstract:

    Purpose To compare Contrast Sensitivity and color vision in patients in whom blue-light filtering and non–yellow-tinted intraocular lenses (IOLs) were implanted. Setting Refractive Surgery Unit, Hospital NISA Valencia al Mar, Valencia, Spain. Methods Forty eyes of 20 patients were enrolled in a blue-light filtering fellow-eye control study; patients were implanted with a yellow-tinted IOL (AcrySof Natural, Alcon) in 1 eye and a non–yellow-tinted IOL (AcrySof SA60AT, Alcon) in the fellow eye after cataract surgery. Three months postoperatively, monocular Contrast Sensitivity function was measured with the CSV 1000-E Contrast Sensitivity chart at distance and the color discrimination with the Farnsworth-Munsell 100 Hue test. Results Eyes implanted with blue-light filtering IOLs showed similar Contrast Sensitivity to that in fellow eyes implanted with non–yellow-tinted IOLs (P>.1). Both types of IOLs showed normal Contrast Sensitivity values (normalized log-Contrast Sensitivity about 1.0). There were no statistically significant differences in chromatic discrimination between the 2 types of IOLs (P = .56). Conclusion The use of blue-light filtering IOLs is more advisable because they are capable of protecting the retina against ultraviolet light without disturbance of Contrast Sensitivity and chromatic vision, which produces subjective impairment in visual function.

  • distance and near Contrast Sensitivity function after multifocal intraocular lens implantation
    Journal of Cataract and Refractive Surgery, 2003
    Co-Authors: Robert Montesmico, Jorge L Alio
    Abstract:

    Abstract Purpose To evaluate Contrast Sensitivity at distance and near after multifocal intraocular lens (IOL) implantation. Setting Ophthalmologic Institute of Alicante, University Miguel Hernandez, Alicante, Spain. Methods Contrast Sensitivity was measured with the Stereo Optical Functional Acuity Contrast Test at distance and near in 21 patients with a refractive multifocal IOL (Array SA-40N, AMO). A control group with a monofocal IOL (SI-40NB, AMO) was also studied to allow comparison of results. Contrast Sensitivity was measured 1, 3, 6, 12, and 18 months after IOL implantation. Results There was a statistically significant greater reduction in Contrast Sensitivity at distance at all spatial frequencies in the multifocal group than in the monofocal group during the first month. At 3 months, Contrast Sensitivity at 12 and 18 cycles per deg remained reduced in the multifocal group; Contrast Sensitivity at the other frequencies did not differ from that in the monofocal group ( P > 0.1). At 6, 12, and 18 months, Contrast Sensitivity at all spatial frequencies was not significantly different between groups ( P > 0.1). There was a statistically significant greater reduction in near Contrast Sensitivity in the multifocal group than in the monofocal group at all spatial frequencies during the first and third month after surgery ( P P > 0.1). Contrast Sensitivity at distance and near in the multifocal group improved over time ( P Conclusions The Array IOL provided Contrast Sensitivity at distance comparable to that obtained with the monofocal IOL between 3 and 6 months after implantation. Near Contrast Sensitivity improved over time but was always lower than at distance and in the monofocal near-corrected patients, which is acceptable to avoid near visual function degradation.

  • choice of spatial frequency for Contrast Sensitivity evaluation after corneal refractive surgery
    Journal of Refractive Surgery, 2001
    Co-Authors: Robert Montesmico, Neil W Charman
    Abstract:

    PURPOSE: To study the utility of measurements of Contrast Sensitivity at different spatial frequencies as an index of visual recovery following refractive surgery. METHODS: Contrast Sensitivity at 1.5, 3, 6, 12, and 18 c/deg was measured with the Stereo Optical FACT chart in 20 patients after photorefractive keratectomy (PRK) using the Nidek EC-5000 excimer laser system, and in 18 patients following laser in situ keratomileusis (LASIK). Contrast Sensitivity was measured preoperatively and 1, 3, 6, and 12 months after surgery. RESULTS: Results showed a statistically significant reduction (P .1). In LASIK patients, decreased Contrast Sensitivity values 1 month after surgery were also obtained at all spatial frequencies. After 3 months, Contrast Sensitivity at 1.5 and 3 c/deg had recovered and did not differ significantly from preoperative values (P>.1), although Contrast Sensitivity at other frequencies remained reduced (P .1). CONCLUSIONS: Contrast Sensitivity measurements at 6 and 12 c/deg appear to be most useful in the assessment of patients who have undergone laser refractive surgery because defocus and optical aberrations primarily affect the higher spatial frequencies.

Jorge L Alio - One of the best experts on this subject based on the ideXlab platform.

  • distance and near Contrast Sensitivity function after multifocal intraocular lens implantation
    Journal of Cataract and Refractive Surgery, 2003
    Co-Authors: Robert Montesmico, Jorge L Alio
    Abstract:

    Abstract Purpose To evaluate Contrast Sensitivity at distance and near after multifocal intraocular lens (IOL) implantation. Setting Ophthalmologic Institute of Alicante, University Miguel Hernandez, Alicante, Spain. Methods Contrast Sensitivity was measured with the Stereo Optical Functional Acuity Contrast Test at distance and near in 21 patients with a refractive multifocal IOL (Array SA-40N, AMO). A control group with a monofocal IOL (SI-40NB, AMO) was also studied to allow comparison of results. Contrast Sensitivity was measured 1, 3, 6, 12, and 18 months after IOL implantation. Results There was a statistically significant greater reduction in Contrast Sensitivity at distance at all spatial frequencies in the multifocal group than in the monofocal group during the first month. At 3 months, Contrast Sensitivity at 12 and 18 cycles per deg remained reduced in the multifocal group; Contrast Sensitivity at the other frequencies did not differ from that in the monofocal group ( P > 0.1). At 6, 12, and 18 months, Contrast Sensitivity at all spatial frequencies was not significantly different between groups ( P > 0.1). There was a statistically significant greater reduction in near Contrast Sensitivity in the multifocal group than in the monofocal group at all spatial frequencies during the first and third month after surgery ( P P > 0.1). Contrast Sensitivity at distance and near in the multifocal group improved over time ( P Conclusions The Array IOL provided Contrast Sensitivity at distance comparable to that obtained with the monofocal IOL between 3 and 6 months after implantation. Near Contrast Sensitivity improved over time but was always lower than at distance and in the monofocal near-corrected patients, which is acceptable to avoid near visual function degradation.

  • Contrast Sensitivity after laser in situ keratomileusis
    Journal of Cataract and Refractive Surgery, 1998
    Co-Authors: Juan J Perezsantonja, Hani F Sakla, Jorge L Alio
    Abstract:

    Abstract Purpose: To evaluate the effect on Contrast Sensitivity function of laser in situ keratomileusis (LASIK) for the correction of myopia. Setting. Alicante Institute of Ophthalmology, University of Alicante, Spain. Methods: Fourteen eyes of 10 patients had LASIK to correct myopia ranging from 6.00 to 19.50 diopters (D). Mean preoperative myopia was 10.39 D ± 3.69 (SD). Contrast Sensitivity was tested preoperatively and 1, 3, and 6 months postoperatively using the CVS-1000E Contrast Sensitivity unit (VectorVision). Results: Contrast Sensitivity decreased 1 month postoperatively; the decrease was significant only at the low and intermediate spatial frequencies of 3 and 6 cycles per degree (cpd) ( P = .034 and .030, respectively). Starting from the first month, there was rapid recovery of Contrast Sensitivity and at the third month, no statistically significant decrease at all spatial frequencies. Six months after surgery, there was an increase in Contrast Sensitivity values at 3, 12, and 18 cpd, although the changes were not significant. Conclusion: Although LASIK decreased Contrast Sensitivity values at low and intermediate spatial frequencies for 1 month after surgery, these values rapidly returned to the preoperative values at 3 months. The improvement at certain frequencies at 6 months suggests that LASIK can improve the quality of vision in eyes with moderate and high myopia.

Kazunori Miyata - One of the best experts on this subject based on the ideXlab platform.

  • Contrast Sensitivity function and ocular higher order wavefront aberrations in normal human eyes
    Ophthalmology, 2006
    Co-Authors: Tetsuro Oshika, Tadatoshi Tokunaga, Tomokazu Samejima, C Okamoto, Kazunori Miyata
    Abstract:

    Purpose To investigate the relation between Contrast Sensitivity function and ocular higher-order wavefront aberrations in normal human eyes. Study Design Prospective observational case series. Participants Three hundred seven eyes of 161 normal subjects, ranging in age from 15 to 60 years (30.9±8.0 [mean ± standard deviation]). Methods Ocular higher-order aberrations were measured for a 4-mm pupil using the Hartmann–Shack wavefront analyzer. The root-mean-square of the third- and fourth-order Zernike coefficients was used to represent comalike and spherical-like aberrations, respectively. We measured Contrast Sensitivity, low-Contrast visual acuity (VA), and letter Contrast Sensitivity. From the Contrast Sensitivity data, the area under the log Contrast Sensitivity function (AULCSF) was calculated. Pupil diameter in a photopic condition was recorded using a digital camera. Results Multiple linear regression analysis revealed that comalike aberration ( P = 0.002) was significantly associated with AULCSF, but spherical-like aberration ( P = 0.200), age ( P = 0.185), and photopic pupil diameter ( P =0.252) were not. Comalike aberration showed a significant correlation with low-Contrast VA ( P P = 0.293), age ( P = 0.266), and pupil diameter ( P = 0.756) did not. Comalike aberration was found to be significantly associated with letter Contrast Sensitivity ( P P =0.082), age ( P = 0.370), and pupil diameter ( P = 0.160) were not. Conclusions In normal human eyes, comalike aberration of the eye significantly influences Contrast Sensitivity function.

  • ocular higher order aberrations and Contrast Sensitivity after conventional laser in situ keratomileusis
    Investigative Ophthalmology & Visual Science, 2004
    Co-Authors: N Yamane, Kazunori Miyata, Tomokazu Samejima, Takahiro Hiraoka, Takahiro Kiuchi, Fumiki Okamoto, Yoko Hirohara, Toshifumi Mihashi, Tetsuro Oshika
    Abstract:

    PURPOSE. To investigate prospectively the relation between induced changes in higher-order aberrations of the eye and changes in Contrast Sensitivity by conventional laser in situ keratomileusis (LASIK) for myopia. METHODS. In 200 eyes of 110 consecutive patients (mean age, 32.7 8.4 years) undergoing LASIK, ocular aberrations and Contrast Sensitivity function were determined before and 1 month after surgery. The amount of myopic correction was 5.2 2.8 D (range, 1.0 –13.0). Ocular higher-order aberrations were measured for a 4-mm pupil using the Hartmann-Shack wavefront analyzer (KR-9000PW; Topcon, Tokyo, Japan). The root mean square (RMS) of the third- and fourth-order Zernike coefficients was used to represent coma- and spherical-like aberrations, respectively. Total higher-order aberrations were calculated as the RMS of the third- and fourth-order coefficients. Contrast Sensitivity and low-Contrast visual acuity were measured. From the Contrast Sensitivity data, the area under the log Contrast Sensitivity function (AULCSF) was calculated. RESULTS. LASIK significantly improved logMAR best corrected visual acuity (Wilcoxon signed-rank test, P 0.001), but significantly reduced AULCSF (P 0.001) and low-Contrast visual acuity (P 0.007). Total higher-order (P 0.001), coma-like (P 0.001), and spherical-like (P 0.001) aberrations were significantly increased after LASIK. The greater the amount of achieved myopia correction was, the more the changes in Contrast Sensitivity function and ocular higher-order aberrations were. The induced changes in AULCSF by LASIK showed significant correlations with changes in total higher-order (Pearson r 0.221, P 0.003), coma-like (r 0.205, P 0.006), and spherical-like (r 0.171, P 0.022) aberrations. The changes in logMAR low-Contrast visual acuity by surgery significantly correlated with changes in total higher-order (r 0.222, P 0.003), coma-like (r 0.201, P 0.007), and spherical-like (r 0.207, P 0.005) aberrations. CONCLUSIONS. Conventional LASIK significantly increases ocular higher-order aberrations, which compromise the postoperative Contrast Sensitivity function. (Invest Ophthalmol Vis Sci. 2004; 45:3986 –3990) DOI:10.1167/iovs.04-0629