The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform

Peter J. Mcdonnell - One of the best experts on this subject based on the ideXlab platform.

  • Keratitis as a Complication of Bilateral, Simultaneous Radial Keratotomy
    American journal of ophthalmology, 1994
    Co-Authors: Karin Szerenyi, Ronald E. Smith, Jan M. Mcdonnell, John A. Irvine, Peter J. Mcdonnell
    Abstract:

    During a one-month period, we examined four patients referred for evaluation of probable microbial keratitis after bilateral, simultaneous radial keratotomy. Each patient had midstromal infiltrates compatible with microbial keratitis that involved one or more of the radial incisions. In two patients the keratitis was bilateral. All patients had been treated empirically with antibiotic agents; superficial cultures with cotton-tipped applicators and Corneal scraping by inserting a platinum spatula into the radial incisions were negative. Corneal Biopsy of one patient disclosed gram-positive rods and culture of the Biopsy specimen grew diphtheroids. The infiltrates gradually resolved over a period of several months with intensive antibiotic therapy. Sight-threatening infectious keratitis can occur after radial keratotomy, and we believe that simultaneous bilateral ocular surgery of any kind should be discouraged.

Stephanie Watson - One of the best experts on this subject based on the ideXlab platform.

  • Corneal Biopsy for diagnosis of recalcitrant microbial keratitis
    Graefe's Archive for Clinical and Experimental Ophthalmology, 2018
    Co-Authors: Dana Robaei, U-teng Chan, Pauline Khoo, Svetlana Cherepanoff, Jane Hanrahan, Stephanie Watson
    Abstract:

    Purpose To document the findings of Corneal biopsies for progressive microbial keratitis in a large tertiary referral institution. Methods A retrospective medical records review of all patients who underwent at least one Corneal Biopsy for the diagnosis of microbial keratitis at Sydney Eye Hospital, Australia between January 1, 2010 and December 31, 2016 was performed. Results Thirty-eight patients (18 men and 20 women) underwent a Corneal Biopsy for progressive microbial keratitis unresponsive to broad-spectrum topical antimicrobials. Risk factors for microbial keratitis included contact lens wear in 8 (21%), recent intraocular surgery in 5 cases (13%), recent agricultural trauma in 3 cases (8%), exposure keratopathy due to Graves’ orbitopathy in 1 case (3%), and profound systemic immunosuppression due to chemotherapy for leukaemia in 1 case (3%). The remaining 20 patients had no identifiable risk factors. Fifteen patients (39%) had a positive Biopsy result, which identified bacteria in 6 cases and Mycobacteria in 1 case, both by culture of the Biopsy specimen. Three cases of fungus were identified on culture of Biopsy specimen, two of which were also confirmed on histopathology and an additional case was identified from histopathology alone. A single case of Acanthamoeba was diagnosed by culture and histopathology, and an additional 3 cases were diagnosed on histopathology alone. A Corneal Biopsy yielded new organisms in 73% (11/15) cases where the culture results of Biopsy specimens were positive. Conclusion Corneal Biopsy is an important tool in the diagnosis of progressive keratitis, often identifying causal organisms not found on Corneal scraping alone.

Dana Robaei - One of the best experts on this subject based on the ideXlab platform.

  • Corneal Biopsy for diagnosis of recalcitrant microbial keratitis
    Graefe's Archive for Clinical and Experimental Ophthalmology, 2018
    Co-Authors: Dana Robaei, U-teng Chan, Pauline Khoo, Svetlana Cherepanoff, Jane Hanrahan, Stephanie Watson
    Abstract:

    Purpose To document the findings of Corneal biopsies for progressive microbial keratitis in a large tertiary referral institution. Methods A retrospective medical records review of all patients who underwent at least one Corneal Biopsy for the diagnosis of microbial keratitis at Sydney Eye Hospital, Australia between January 1, 2010 and December 31, 2016 was performed. Results Thirty-eight patients (18 men and 20 women) underwent a Corneal Biopsy for progressive microbial keratitis unresponsive to broad-spectrum topical antimicrobials. Risk factors for microbial keratitis included contact lens wear in 8 (21%), recent intraocular surgery in 5 cases (13%), recent agricultural trauma in 3 cases (8%), exposure keratopathy due to Graves’ orbitopathy in 1 case (3%), and profound systemic immunosuppression due to chemotherapy for leukaemia in 1 case (3%). The remaining 20 patients had no identifiable risk factors. Fifteen patients (39%) had a positive Biopsy result, which identified bacteria in 6 cases and Mycobacteria in 1 case, both by culture of the Biopsy specimen. Three cases of fungus were identified on culture of Biopsy specimen, two of which were also confirmed on histopathology and an additional case was identified from histopathology alone. A single case of Acanthamoeba was diagnosed by culture and histopathology, and an additional 3 cases were diagnosed on histopathology alone. A Corneal Biopsy yielded new organisms in 73% (11/15) cases where the culture results of Biopsy specimens were positive. Conclusion Corneal Biopsy is an important tool in the diagnosis of progressive keratitis, often identifying causal organisms not found on Corneal scraping alone.

  • Corneal Biopsy for diagnosis of recalcitrant microbial keratitis.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2018
    Co-Authors: Dana Robaei, U-teng Chan, Pauline Khoo, Svetlana Cherepanoff, Jane Hanrahan, Stephanie L Watson
    Abstract:

    Purpose To document the findings of Corneal biopsies for progressive microbial keratitis in a large tertiary referral institution.

Karin Szerenyi - One of the best experts on this subject based on the ideXlab platform.

  • Keratitis as a Complication of Bilateral, Simultaneous Radial Keratotomy
    American journal of ophthalmology, 1994
    Co-Authors: Karin Szerenyi, Ronald E. Smith, Jan M. Mcdonnell, John A. Irvine, Peter J. Mcdonnell
    Abstract:

    During a one-month period, we examined four patients referred for evaluation of probable microbial keratitis after bilateral, simultaneous radial keratotomy. Each patient had midstromal infiltrates compatible with microbial keratitis that involved one or more of the radial incisions. In two patients the keratitis was bilateral. All patients had been treated empirically with antibiotic agents; superficial cultures with cotton-tipped applicators and Corneal scraping by inserting a platinum spatula into the radial incisions were negative. Corneal Biopsy of one patient disclosed gram-positive rods and culture of the Biopsy specimen grew diphtheroids. The infiltrates gradually resolved over a period of several months with intensive antibiotic therapy. Sight-threatening infectious keratitis can occur after radial keratotomy, and we believe that simultaneous bilateral ocular surgery of any kind should be discouraged.

Ronald E. Smith - One of the best experts on this subject based on the ideXlab platform.

  • Traumatic Acremonium atrogriseum keratitis following laser-assisted in situ keratomileusis.
    Archives of ophthalmology (Chicago Ill. : 1960), 2000
    Co-Authors: Russell W. Read, Roy S. Chuck, Narsing A. Rao, Ronald E. Smith
    Abstract:

    A 52-year-old man underwent bilateral laser-assisted in situ keratomileusis. Eight months later, he sustained a penetrating Corneal injury to the left eye. A dense white infiltrate, unresponsive to antimicrobial therapy, developed in the Corneal stroma. Corneal Biopsy and eventual penetrating keratoplasty were performed, and both specimens demonstrated fungal elements with branching, septate hyphae. Culture identified the organism as Acremonium atrogriseum. Histopathologic features of this organism and its differentiation from other, more common fungal organisms are discussed herein.

  • Keratitis as a Complication of Bilateral, Simultaneous Radial Keratotomy
    American journal of ophthalmology, 1994
    Co-Authors: Karin Szerenyi, Ronald E. Smith, Jan M. Mcdonnell, John A. Irvine, Peter J. Mcdonnell
    Abstract:

    During a one-month period, we examined four patients referred for evaluation of probable microbial keratitis after bilateral, simultaneous radial keratotomy. Each patient had midstromal infiltrates compatible with microbial keratitis that involved one or more of the radial incisions. In two patients the keratitis was bilateral. All patients had been treated empirically with antibiotic agents; superficial cultures with cotton-tipped applicators and Corneal scraping by inserting a platinum spatula into the radial incisions were negative. Corneal Biopsy of one patient disclosed gram-positive rods and culture of the Biopsy specimen grew diphtheroids. The infiltrates gradually resolved over a period of several months with intensive antibiotic therapy. Sight-threatening infectious keratitis can occur after radial keratotomy, and we believe that simultaneous bilateral ocular surgery of any kind should be discouraged.