The Experts below are selected from a list of 312 Experts worldwide ranked by ideXlab platform

Tueng T Shen - One of the best experts on this subject based on the ideXlab platform.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Xiaoli Li, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen, Xingde Li
    Abstract:

    PURPOSE: To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty. METHODS: A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed for lamellar keratoplasty. Twenty-seven donor corneas were analyzed. Four donor corneas were used as controls, whereas the rest were processed into donor Corneal buttons for lamellar transplantation by using hand dissection, a microkeratome, or a femtosecond laser. UHR-OCT was also used to noninvasively characterize and monitor the viable Corneal Tissue immersed in storage medium over 3 weeks. RESULTS: The UHR-OCT captured high-resolution images of the donor Corneal Tissue in situ. This noninvasive technique showed the changes in donor Corneal Tissue morphology with time while in storage medium. The characteristics of the lamellar Corneal Tissue with each processing modality were clearly visible by UHR-OCT. The in situ characterization of the femtosecond laser-cut Corneal Tissue was noted to have more interface debris than shown by routine histology. The effects of the femtosecond laser microcavitation bubbles on the Corneal Tissue were well visualized at the edges of the lamellar flap while in storage medium. CONCLUSIONS: The results of our feasibility study show that UHR-OCT can provide superb, in situ microstructural characterization of eye bank Corneal Tissue noninvasively. The UHR-OCT interface findings and Corneal endothelial disc thickness uniformity analysis are valuable information that may be used to optimize the modalities and parameters for lamellar Tissue processing. The UHR-OCT is a powerful approach that will allow us to further evaluate the Tissue response to different processing techniques for posterior lamellar keratoplasty. It may also provide information that can be used to correlate with postoperative clinical outcomes. UHR-OCT has the potential to become a routine part of Tissue analysis for any eye bank or centers creating customized lamellar Corneal Tissue for transplantation.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen
    Abstract:

    Purpose:To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty.Methods:A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed f

Jamin S Brown - One of the best experts on this subject based on the ideXlab platform.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Xiaoli Li, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen, Xingde Li
    Abstract:

    PURPOSE: To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty. METHODS: A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed for lamellar keratoplasty. Twenty-seven donor corneas were analyzed. Four donor corneas were used as controls, whereas the rest were processed into donor Corneal buttons for lamellar transplantation by using hand dissection, a microkeratome, or a femtosecond laser. UHR-OCT was also used to noninvasively characterize and monitor the viable Corneal Tissue immersed in storage medium over 3 weeks. RESULTS: The UHR-OCT captured high-resolution images of the donor Corneal Tissue in situ. This noninvasive technique showed the changes in donor Corneal Tissue morphology with time while in storage medium. The characteristics of the lamellar Corneal Tissue with each processing modality were clearly visible by UHR-OCT. The in situ characterization of the femtosecond laser-cut Corneal Tissue was noted to have more interface debris than shown by routine histology. The effects of the femtosecond laser microcavitation bubbles on the Corneal Tissue were well visualized at the edges of the lamellar flap while in storage medium. CONCLUSIONS: The results of our feasibility study show that UHR-OCT can provide superb, in situ microstructural characterization of eye bank Corneal Tissue noninvasively. The UHR-OCT interface findings and Corneal endothelial disc thickness uniformity analysis are valuable information that may be used to optimize the modalities and parameters for lamellar Tissue processing. The UHR-OCT is a powerful approach that will allow us to further evaluate the Tissue response to different processing techniques for posterior lamellar keratoplasty. It may also provide information that can be used to correlate with postoperative clinical outcomes. UHR-OCT has the potential to become a routine part of Tissue analysis for any eye bank or centers creating customized lamellar Corneal Tissue for transplantation.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen
    Abstract:

    Purpose:To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty.Methods:A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed f

Thomas D. Lindquist - One of the best experts on this subject based on the ideXlab platform.

  • Minimizing the risk of disease transmission during Corneal Tissue processing.
    Cornea, 2009
    Co-Authors: Thomas D. Lindquist, Thomas D Miller, Jennifer L Elsen, Paul J Lignoski
    Abstract:

    Corneal transplantation is undergoing significant change because the dysfunctional portion of the cornea may now be selectively transplanted. After recovery of corneoscleral Tissue, further processing of such Tissue as in microkeratome preparation of endothelial keratoplasty lenticules is defined as "open-container processing" by the Eye Bank Association of America. Airborne bacterial contamination during preparation of Corneal Tissue is a potential source of postoperative infection. This review addresses ways to minimize the risk of disease transmission as Corneal Tissue is processed for lamellar keratoplasty, endothelial keratoplasty, or femtosecond laser-assisted penetrating keratoplasty and to minimize risk to eye bank personnel or physicians preparing the Tissue. Secondly, quality assurance measures are described that qualify the environment in which Corneal Tissue is being processed. We propose that the environment in which Corneal Tissue is being processed must be able to demonstrate acceptable levels of airborne microbial contamination annually as measured by settle plates to estimate airborne bacterial sedimentation. It is recommended that any environment where Corneal Tissue is prepared should meet the minimum standard of a conventional operating room which is

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Xiaoli Li, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen, Xingde Li
    Abstract:

    PURPOSE: To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty. METHODS: A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed for lamellar keratoplasty. Twenty-seven donor corneas were analyzed. Four donor corneas were used as controls, whereas the rest were processed into donor Corneal buttons for lamellar transplantation by using hand dissection, a microkeratome, or a femtosecond laser. UHR-OCT was also used to noninvasively characterize and monitor the viable Corneal Tissue immersed in storage medium over 3 weeks. RESULTS: The UHR-OCT captured high-resolution images of the donor Corneal Tissue in situ. This noninvasive technique showed the changes in donor Corneal Tissue morphology with time while in storage medium. The characteristics of the lamellar Corneal Tissue with each processing modality were clearly visible by UHR-OCT. The in situ characterization of the femtosecond laser-cut Corneal Tissue was noted to have more interface debris than shown by routine histology. The effects of the femtosecond laser microcavitation bubbles on the Corneal Tissue were well visualized at the edges of the lamellar flap while in storage medium. CONCLUSIONS: The results of our feasibility study show that UHR-OCT can provide superb, in situ microstructural characterization of eye bank Corneal Tissue noninvasively. The UHR-OCT interface findings and Corneal endothelial disc thickness uniformity analysis are valuable information that may be used to optimize the modalities and parameters for lamellar Tissue processing. The UHR-OCT is a powerful approach that will allow us to further evaluate the Tissue response to different processing techniques for posterior lamellar keratoplasty. It may also provide information that can be used to correlate with postoperative clinical outcomes. UHR-OCT has the potential to become a routine part of Tissue analysis for any eye bank or centers creating customized lamellar Corneal Tissue for transplantation.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen
    Abstract:

    Purpose:To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty.Methods:A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed f

Bernie Iliakis - One of the best experts on this subject based on the ideXlab platform.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Xiaoli Li, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen, Xingde Li
    Abstract:

    PURPOSE: To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty. METHODS: A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed for lamellar keratoplasty. Twenty-seven donor corneas were analyzed. Four donor corneas were used as controls, whereas the rest were processed into donor Corneal buttons for lamellar transplantation by using hand dissection, a microkeratome, or a femtosecond laser. UHR-OCT was also used to noninvasively characterize and monitor the viable Corneal Tissue immersed in storage medium over 3 weeks. RESULTS: The UHR-OCT captured high-resolution images of the donor Corneal Tissue in situ. This noninvasive technique showed the changes in donor Corneal Tissue morphology with time while in storage medium. The characteristics of the lamellar Corneal Tissue with each processing modality were clearly visible by UHR-OCT. The in situ characterization of the femtosecond laser-cut Corneal Tissue was noted to have more interface debris than shown by routine histology. The effects of the femtosecond laser microcavitation bubbles on the Corneal Tissue were well visualized at the edges of the lamellar flap while in storage medium. CONCLUSIONS: The results of our feasibility study show that UHR-OCT can provide superb, in situ microstructural characterization of eye bank Corneal Tissue noninvasively. The UHR-OCT interface findings and Corneal endothelial disc thickness uniformity analysis are valuable information that may be used to optimize the modalities and parameters for lamellar Tissue processing. The UHR-OCT is a powerful approach that will allow us to further evaluate the Tissue response to different processing techniques for posterior lamellar keratoplasty. It may also provide information that can be used to correlate with postoperative clinical outcomes. UHR-OCT has the potential to become a routine part of Tissue analysis for any eye bank or centers creating customized lamellar Corneal Tissue for transplantation.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen
    Abstract:

    Purpose:To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty.Methods:A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed f

Florence Baluyot - One of the best experts on this subject based on the ideXlab platform.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Xiaoli Li, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen, Xingde Li
    Abstract:

    PURPOSE: To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty. METHODS: A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed for lamellar keratoplasty. Twenty-seven donor corneas were analyzed. Four donor corneas were used as controls, whereas the rest were processed into donor Corneal buttons for lamellar transplantation by using hand dissection, a microkeratome, or a femtosecond laser. UHR-OCT was also used to noninvasively characterize and monitor the viable Corneal Tissue immersed in storage medium over 3 weeks. RESULTS: The UHR-OCT captured high-resolution images of the donor Corneal Tissue in situ. This noninvasive technique showed the changes in donor Corneal Tissue morphology with time while in storage medium. The characteristics of the lamellar Corneal Tissue with each processing modality were clearly visible by UHR-OCT. The in situ characterization of the femtosecond laser-cut Corneal Tissue was noted to have more interface debris than shown by routine histology. The effects of the femtosecond laser microcavitation bubbles on the Corneal Tissue were well visualized at the edges of the lamellar flap while in storage medium. CONCLUSIONS: The results of our feasibility study show that UHR-OCT can provide superb, in situ microstructural characterization of eye bank Corneal Tissue noninvasively. The UHR-OCT interface findings and Corneal endothelial disc thickness uniformity analysis are valuable information that may be used to optimize the modalities and parameters for lamellar Tissue processing. The UHR-OCT is a powerful approach that will allow us to further evaluate the Tissue response to different processing techniques for posterior lamellar keratoplasty. It may also provide information that can be used to correlate with postoperative clinical outcomes. UHR-OCT has the potential to become a routine part of Tissue analysis for any eye bank or centers creating customized lamellar Corneal Tissue for transplantation.

  • in situ ultrahigh resolution optical coherence tomography characterization of eye bank Corneal Tissue processed for lamellar keratoplasty
    Cornea, 2008
    Co-Authors: Jamin S Brown, Thomas D. Lindquist, Danling Wang, Florence Baluyot, Bernie Iliakis, Rika Shirakawa, Tueng T Shen
    Abstract:

    Purpose:To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank Corneal Tissue processed for lamellar keratoplasty.Methods:A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor Corneal Tissue that had been processed f