The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform
Eran Zaidel - One of the best experts on this subject based on the ideXlab platform.
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Fiber composition of the human Corpus Callosum.
Brain research, 1992Co-Authors: Francisco Aboitiz, R S Fisher, Arnold B Scheibel, Eran ZaidelAbstract:The densities of fibers of different sizes were calculated in ten regions of the Corpus Callosum of twenty human brains (ten females, ten males). Light microscopic examination revealed a consistent pattern of regional differentiation of fiber types in the Corpus Callosum. Thin fibers are most dense in the anterior Corpus Callosum (genu), and decrease in density posteriorly towards the posterior midbody, where they reach a minimum. Towards the posterior Corpus Callosum (splenium), the density of thin fibers increases again, but in the posterior pole of the Callosum the density decreases locally. Large-diameter fibers show a pattern complementary to that of thin fibers, having a peak of density in the posterior midbody and a local increase of density in the posterior pole of the Corpus Callosum. Across subjects, the overall density of callosal fibers had no significant correlation with callosal area and an increased callosal area indicated an increased total number of fibers crossing through. Considering different fiber sizes, this was only true for small diameter fibers, whose large majority is believed to interconnect association cortex. No sex differences in fiber composition of the Corpus Callosum were found.
L.j. Van Der Knaap - One of the best experts on this subject based on the ideXlab platform.
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how does the Corpus Callosum mediate interhemispheric transfer a review
Behavioural Brain Research, 2011Co-Authors: L.j. Van Der KnaapAbstract:The Corpus Callosum is the largest white matter structure in the human brain, connecting cortical regions of both hemispheres. Complete and partial callosotomies or callosal lesion studies have granted more insight into the function of the Corpus Callosum, namely the facilitation of communication between the cerebral hemispheres. How the Corpus Callosum mediates this information transfer is still a topic of debate. Some pose that the Corpus Callosum maintains independent processing between the two hemispheres, whereas others say that the Corpus Callosum shares information between hemispheres. These theories of inhibition and excitation are further explored by reviewing recent behavioural studies and morphological findings to gain more information about callosal function. Additional information regarding callosal function in relation to altered morphology and dysfunction in disorders is reviewed to add to the discussion of callosal involvement in interhemispheric transfer. Both the excitatory and inhibitory theories seem likely candidates to describe callosal function, however evidence also exists for both functions within the same Corpus Callosum. For future research it would be beneficial to investigate the functional role of the callosal sub regions to get a better understanding of function and use more appropriate experimental methods to determine functional connectivity when looking at interhemispheric transfer.
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The Corpus Callosum and Brain Hemisphere Communication; How does the Corpus Callosum mediate interhemispheric transfer
2010Co-Authors: L.j. Van Der KnaapAbstract:3 History 4 The Corpus Callosum 4 Corpus Callosum Anatomy and Functional Organization 5 Brain Commissures 5 Functional Organization 5 Corpus Callosum Function: The Split Brain 7 Animal Disconnection Studies 7 Human Disconnection Studies 8 Lesion Studies 10 Agenesis of the Corpus Callosum 10 Summary 11 Hemispheric Interaction 12 Interhemispheric Transfer 12 The Inhibitory Model 13 Hemisphere dominance and metacontrol 13 The aging Corpus Callosum 15 The Excitatory Model 16 Summary 17 Callosal Involvement in Disorders 19 Disorders 19 Schizophrenia 19 Autism 20 Alien Hand Syndrome 20 ADHD 21 Bipolar Disorder and Borderline Personality Disorder 21 Summary 21 Discussion 23 Acknowledgements 25 References 26 Image on front page taken from Wilde et al., (2008).
Francisco Aboitiz - One of the best experts on this subject based on the ideXlab platform.
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Fiber composition of the human Corpus Callosum.
Brain research, 1992Co-Authors: Francisco Aboitiz, R S Fisher, Arnold B Scheibel, Eran ZaidelAbstract:The densities of fibers of different sizes were calculated in ten regions of the Corpus Callosum of twenty human brains (ten females, ten males). Light microscopic examination revealed a consistent pattern of regional differentiation of fiber types in the Corpus Callosum. Thin fibers are most dense in the anterior Corpus Callosum (genu), and decrease in density posteriorly towards the posterior midbody, where they reach a minimum. Towards the posterior Corpus Callosum (splenium), the density of thin fibers increases again, but in the posterior pole of the Callosum the density decreases locally. Large-diameter fibers show a pattern complementary to that of thin fibers, having a peak of density in the posterior midbody and a local increase of density in the posterior pole of the Corpus Callosum. Across subjects, the overall density of callosal fibers had no significant correlation with callosal area and an increased callosal area indicated an increased total number of fibers crossing through. Considering different fiber sizes, this was only true for small diameter fibers, whose large majority is believed to interconnect association cortex. No sex differences in fiber composition of the Corpus Callosum were found.
Stephan Arndt - One of the best experts on this subject based on the ideXlab platform.
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an mri study of the Corpus Callosum in autism
American Journal of Psychiatry, 1997Co-Authors: Joseph Piven, James Bailey, Bonnie J Ranson, Stephan ArndtAbstract:Objective: The purpose of this study was to examine the size of subregions of the Corpus Callosum in autistic individuals. Method: The areas of three subregions (anterior, body, and posterior) of the Corpus Callosum were examined on midsagittal magnetic resonance images of 35 autistic subjects whose mean age was 18 years and 36 healthy comparison subjects matched on age and IQ. Results: After controlling for total brain volume, gender, and performance IQ, the authors detected a significantly smaller size of the body and posterior subregions of the Corpus Callosum in the autistic individuals. Conclusions: In the context of recent reports of increased brain size in autism, several possible mechanisms are considered in exploring the significance of a smaller relative size of the Corpus Callosum in autism. (Am J Psychiatry 1997; 154:1051‐1056)
R S Fisher - One of the best experts on this subject based on the ideXlab platform.
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Fiber composition of the human Corpus Callosum.
Brain research, 1992Co-Authors: Francisco Aboitiz, R S Fisher, Arnold B Scheibel, Eran ZaidelAbstract:The densities of fibers of different sizes were calculated in ten regions of the Corpus Callosum of twenty human brains (ten females, ten males). Light microscopic examination revealed a consistent pattern of regional differentiation of fiber types in the Corpus Callosum. Thin fibers are most dense in the anterior Corpus Callosum (genu), and decrease in density posteriorly towards the posterior midbody, where they reach a minimum. Towards the posterior Corpus Callosum (splenium), the density of thin fibers increases again, but in the posterior pole of the Callosum the density decreases locally. Large-diameter fibers show a pattern complementary to that of thin fibers, having a peak of density in the posterior midbody and a local increase of density in the posterior pole of the Corpus Callosum. Across subjects, the overall density of callosal fibers had no significant correlation with callosal area and an increased callosal area indicated an increased total number of fibers crossing through. Considering different fiber sizes, this was only true for small diameter fibers, whose large majority is believed to interconnect association cortex. No sex differences in fiber composition of the Corpus Callosum were found.
