The Experts below are selected from a list of 279 Experts worldwide ranked by ideXlab platform
Enrico Ferrante - One of the best experts on this subject based on the ideXlab platform.
-
p040 primary valsalva maneuver Headache without primary Cough Headache
Journal of Headache and Pain, 2015Co-Authors: Enrico FerranteAbstract:Background The uncommon Headache related to a Valsalva maneuver (VM) is coded within the International Headache Society Classification (ICHD-3beta) among “Other primary Headaches”, 4.1 “Primary Cough Headache” (PCH). This chapter deals with Headaches precipitated by Coughing or straining in the absence of any systemic or intracranial disorder. The clinical features of the pain are characterized by sudden onset, lasting from 1 s to 2 hours, and brought on by and occurring only in association with Coughing, straining, and/or a VM. Neuroimaging plays an important role in differentiating secondary forms.
-
modified valsalva test differentiates primary from secondary Cough Headache
Journal of Headache and Pain, 2013Co-Authors: Enrico FerranteAbstract:I suppose that the patient number 14, reported in the article of RJ Lane et al. on “Modified Valsalva test differentiates primary from secondary Cough Headache ”in a recent issue of your esteemed journal, was probably suffering from spontaneous intracranial hypotension syndrome (SIH) caused by cervical manipulation.
-
Focus on therapy of the Chapter IV Headaches provoked by exertional factors: primary Cough Headache, primary exertional Headache and primary Headache associated with sexual activity
The Journal of Headache and Pain, 2010Co-Authors: Marta Allena, Paolo Rossi, Cristina Tassorelli, Enrico Ferrante, Carlo Lisotto, Giuseppe NappiAbstract:Primary Cough Headache, primary exertional Headache and primary Headache associated with sexual activity are distinct entities, even though they share several features: acute onset, the absence of structural brain disease and exertional factors as precipitating events. In this short review, we illustrate the possible treatment strategies on the basis of information collected from a systematic analysis of the international literature.
Shuujiun Wang - One of the best experts on this subject based on the ideXlab platform.
-
Cough Headache a study of 83 consecutive patients
Cephalalgia, 2009Co-Authors: P K Chen, Jongling Fuh, Shuujiun WangAbstract:To delineate the differences in clinical characteristics and evaluate the outcome between primary and secondary Cough Headache, 83 consecutive patients (59M/24F, mean age 61.5 +/- 17.7 years) with Cough Headache (1.2%) out of 7100 patients in a Headache clinic were studied. All of them received brain imaging studies. Most did not have relevant brain lesions (n = 74, 89.2%, primary group) except for nine patients (10.8%, the secondary group). Most of the intracranial lesions were located in the posterior fossa (n = 6, 67%), including only two patients with Chiari malformation. The primary group had a higher response rate to indomethacin than the secondary group (72.7% vs. 37.5 %, P = 0.046). Mild to moderate Headache intensity and age onset 30 min. Clinical features, neurological examinations and drug response could not safely differentiate primary from secondary Cough Headache. Neuroimaging studies are required in each patient.
-
primary Cough Headache is associated with posterior fossa crowdedness a morphometric mri study
Cephalalgia, 2004Co-Authors: Yenyu Chen, Jongling Fuh, Jiingfeng Lirng, Fengchi Chang, Huicheng Cheng, Shuujiun WangAbstract:The aetiology of primary Cough Headache (PCH) is obscure. The aim of this study was to investigate the magnetic resonance (MR) morphometric characteristics of the posterior cranial fossa (PCF) in patients with PCH. Eighteen consecutive patients with PCH (14M/4F, mean age 75.1 +/- 6.0 years) and 18 sex- and age-matched control subjects were recruited for study. Based on the midline sagittal MR images, parameters indicating posterior fossa crowdedness were measured. Compared with controls, patients with PCH had a similar size of hindbrain tissue area but a significantly smaller PCF area, resulting in a higher mean hindbrain/PCF ratio (0.78 +/- 0.04 vs. 0.73 +/- 0.06, P = 0.005). In addition, these patients also had a lower position of the cerebellar tonsillar tip, a shorter clivus length and shorter distances from the clivus to the mid-pons and from the basion to the medulla than the control group. Patients with PCH were associated with a more crowded PCF, which might be a contributing factor for the pathogenesis of this Headache syndrome.
-
benign Cough Headache is responsive to acetazolamide
Neurology, 2000Co-Authors: Shuujiun Wang, Jongling FuhAbstract:Benign Cough Headache (BCH) is a rare Headache syndrome.1,2 It is defined by the International Headache Society (IHS) as a Headache precipitated by Coughing in the absence of any intracranial disorder. The Headache is usually bilateral and of sudden onset, lasting less than 1 minute, and may be prevented by the avoidance of Coughing.3 Most patients are responsive to indomethacin, although lumbar puncture has been advocated by Raskin.4 He suggested that both indomethacin and lumbar puncture were effective after a sudden decrease in intracranial pressure (ICP), and proposed that determination of the nature of the receptors that were sensitive to ICP alterations was probably the key to understanding this disorder.4 We conducted an open-label trial using acetazolamide in the treatment of BCH. The objectives were to provide an alternative treatment and to test the hypothesis that the efficacy of indomethacin and lumbar puncture results from the reduction of CSF volume. Five outpatients (four men, …
P Mason - One of the best experts on this subject based on the ideXlab platform.
-
zinc gluconate lozenges for treating the common cold a randomized double blind placebo controlled study
Annals of Internal Medicine, 1996Co-Authors: Sherif B Mossad, Michael L Macknin, Sharon V Medendorp, P MasonAbstract:Background : The common cold is one of the most frequent human illnesses and is responsible for substantial morbidity and economic loss. No consistently effective therapy for the common cold has been well documented, but evidence suggests that several possible mechanisms may make zinc an effective treatment. Objective : To test the efficacy of zinc gluconate lozenges in reducing the duration of symptoms caused by the common cold. Design : Randomized, double-blind, placebo-controlled study. Setting : Outpatient department of a large tertiary care center. Patients : 100 employees of the Cleveland Clinic who developed symptoms of the common cold within 24 hours before enrollment. Intervention : Patients in the zinc group (n = 50) received lozenges (one lozenge every 2 hours while awake) containing 13.3 mg of zinc from zinc gluconate as long as they had cold symptoms. Patients in the placebo group (n = 50) received similarly administered lozenges that contained 5% calcium lactate pentahydrate instead of zinc gluconate. Main Outcome Measures : Subjective daily symptom scores for Cough, Headache, hoarseness, muscle ache, nasal drainage, nasal congestion, scratchy throat, sore throat, sneezing, and fever (assessed by oral temperature). Results : The time to complete resolution of symptoms was significantly shorter in the zinc group than in the placebo group (median, 4.4 days compared with 7.6 days ; P< 0.001). The zinc group had significantly fewer days with Coughing (median, 2.0 days compared with 4.5 days ; P= 0.04), Headache (2.0 days and 3.0 days ; P = 0.02), hoarseness (2.0 days and 3.0 days ; P = 0.02), nasal congestion (4.0 days and 6.0 days ; P = 0.002), nasal drainage (4.0 days and 7.0 days ; P < 0.001), and sore throat (1.0 day and 3.0 days ; P < 0.001). The groups did not differ significantly in the resolution of fever, muscle ache, scratchy throat, or sneezing. More patients in the zinc group than in the placebo group had side effects (90% compared with 62% ; P < 0.001), nausea (20% compared with 4% ; P = 0.02), and bad-taste reactions (80% compared with 30% ; P < 0.001). Conclusion : Zinc gluconate in the form and dosage studied significantly reduced the duration of symptoms of the common cold. The mechanism of action of this substance in treating the common cold remains unknown. Individual patients must decide whether the possible beneficial effects of zinc gluconate on cold symptoms outweigh the possible adverse effects.
Peter J Goadsby - One of the best experts on this subject based on the ideXlab platform.
-
primary Cough Headache treated with non invasive vagal nerve stimulation
Neurology, 2020Co-Authors: David Morenoajona, Peter J Goadsby, Maria Dolores Villarmartinez, Jan HoffmannAbstract:Primary Cough Headache (PCH) is a rare neurologic condition accounting for less than 1% of Headaches in specialized neurology clinics, although its prevalence may be underestimated.1,2 PCH is characterized by sudden-onset Headache precipitated by Cough or another Valsalva maneuver in the absence of any intracranial disorder,2 such as posterior fossa malformation.1 The Headache characteristically reaches its peak almost immediately and lasts between 1 second and 2 hours. PCH has been reported to be indomethacin-responsive.1 In an open-label trial daily doses of indomethacin ranging from 50 mg to 200 mg were reported as efficacious in 16 patients with PCH.3 The molecular mechanisms underlying the specific effect of indomethacin in several primary Headaches remain largely unknown. Its use is frequently limited by side effects, among which gastrointestinal disturbances are the most prevalent and serious.1,3 Noninvasive neuromodulation of the cervical branch of the vagus nerve (noninvasive vagal nerve stimulation [nVNS]) is efficacious in other primary Headache disorders, such as cluster Headache.4 It has been reported that other indomethacin-responsive Headaches, namely hemicrania continua and paroxysmal hemicrania, may also respond to noninvasive vagus nerve stimulation nVNS.5
-
primary Cough Headache
2015Co-Authors: Peter J GoadsbyAbstract:The patient, a 51-year-old male, presented with a 10-month history of a new Headache, without any previous history of Headache and in particular no history of Headache with alcohol consumption.
-
benign Cough Headache
Cephalalgia, 2002Co-Authors: Christopher J Boes, Manjit Matharu, Peter J GoadsbyAbstract:Benign Cough Headache is an uncommon primary Headache disorder marked by short-lasting attacks of pain triggered by Coughing. Magnetic resonance imaging of the brain is required to assure that the Cough Headache is truly benign. The aetiology of the pain is unclear, but is probably associated with the brief increased intracranial pressure that attends Coughing. We have reviewed the clinical features, aetiology, differential diagnosis, management, and prognosis of benign Cough Headache.
-
Cough Headache responsive to methysergide
Cephalalgia, 1998Co-Authors: A Bahra, Peter J GoadsbyAbstract:Cough Headache is a very distinct syndrome of Headache precipitated by Coughing, lifting, bending, sneezing, laughing, or straining. The pain can be severe and, if precipitation is difficult to avoid, certainly distressing. The usual treatment is indomethacin, which can be highly effective although recently lumbar puncture has again been advocated. We encountered a patient in whom indomethacin use was relatively contraindicated and who had an apparent response to methysergide.
Jongling Fuh - One of the best experts on this subject based on the ideXlab platform.
-
Cough Headache a study of 83 consecutive patients
Cephalalgia, 2009Co-Authors: P K Chen, Jongling Fuh, Shuujiun WangAbstract:To delineate the differences in clinical characteristics and evaluate the outcome between primary and secondary Cough Headache, 83 consecutive patients (59M/24F, mean age 61.5 +/- 17.7 years) with Cough Headache (1.2%) out of 7100 patients in a Headache clinic were studied. All of them received brain imaging studies. Most did not have relevant brain lesions (n = 74, 89.2%, primary group) except for nine patients (10.8%, the secondary group). Most of the intracranial lesions were located in the posterior fossa (n = 6, 67%), including only two patients with Chiari malformation. The primary group had a higher response rate to indomethacin than the secondary group (72.7% vs. 37.5 %, P = 0.046). Mild to moderate Headache intensity and age onset 30 min. Clinical features, neurological examinations and drug response could not safely differentiate primary from secondary Cough Headache. Neuroimaging studies are required in each patient.
-
primary Cough Headache is associated with posterior fossa crowdedness a morphometric mri study
Cephalalgia, 2004Co-Authors: Yenyu Chen, Jongling Fuh, Jiingfeng Lirng, Fengchi Chang, Huicheng Cheng, Shuujiun WangAbstract:The aetiology of primary Cough Headache (PCH) is obscure. The aim of this study was to investigate the magnetic resonance (MR) morphometric characteristics of the posterior cranial fossa (PCF) in patients with PCH. Eighteen consecutive patients with PCH (14M/4F, mean age 75.1 +/- 6.0 years) and 18 sex- and age-matched control subjects were recruited for study. Based on the midline sagittal MR images, parameters indicating posterior fossa crowdedness were measured. Compared with controls, patients with PCH had a similar size of hindbrain tissue area but a significantly smaller PCF area, resulting in a higher mean hindbrain/PCF ratio (0.78 +/- 0.04 vs. 0.73 +/- 0.06, P = 0.005). In addition, these patients also had a lower position of the cerebellar tonsillar tip, a shorter clivus length and shorter distances from the clivus to the mid-pons and from the basion to the medulla than the control group. Patients with PCH were associated with a more crowded PCF, which might be a contributing factor for the pathogenesis of this Headache syndrome.
-
benign Cough Headache is responsive to acetazolamide
Neurology, 2000Co-Authors: Shuujiun Wang, Jongling FuhAbstract:Benign Cough Headache (BCH) is a rare Headache syndrome.1,2 It is defined by the International Headache Society (IHS) as a Headache precipitated by Coughing in the absence of any intracranial disorder. The Headache is usually bilateral and of sudden onset, lasting less than 1 minute, and may be prevented by the avoidance of Coughing.3 Most patients are responsive to indomethacin, although lumbar puncture has been advocated by Raskin.4 He suggested that both indomethacin and lumbar puncture were effective after a sudden decrease in intracranial pressure (ICP), and proposed that determination of the nature of the receptors that were sensitive to ICP alterations was probably the key to understanding this disorder.4 We conducted an open-label trial using acetazolamide in the treatment of BCH. The objectives were to provide an alternative treatment and to test the hypothesis that the efficacy of indomethacin and lumbar puncture results from the reduction of CSF volume. Five outpatients (four men, …
