Cyanoacrylate Derivative

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Amita Bagal - One of the best experts on this subject based on the ideXlab platform.

Eric J. Stelnicki - One of the best experts on this subject based on the ideXlab platform.

  • Novel bone adhesives: a comparison of bond strengths in vitro
    International journal of oral and maxillofacial surgery, 2013
    Co-Authors: U. Kandalam, A. J. Bouvier, S. B. Casas, Robert L. Smith, A. M. Gallego, James Rothrock, Jeffrey Y. Thompson, Chun Yuh Huang, Eric J. Stelnicki
    Abstract:

    Fracture fixation using adhesive is a promising alternative in craniofacial surgeries, replacing the plates and screws system. The advantages include the ease of application and avoidance of drilling holes that may weaken the bone and cause fractures. In this study the bond strengths of selected adhesives were evaluated and compared with resorbable plates and screws. Four adhesives, octyl-Cyanoacrylate, N-butyl-Cyanoacrylate, a novel methyl-methacrylate, and a novel Cyanoacrylate Derivative, were tested for their microtensile and shear bond strengths. The bone samples were cut into rectangular bars and bonded with selected adhesives for microtensile testing. For the shear bond test, paired bars were bonded at the overlap, while two other sets of bars were attached by a Lactosorb plate using either adhesive or screws. Data were analysed by analysis of variance (ANOVA). The microtensile bond strengths of N-butyl-Cyanoacrylate, novel Cyanoacrylate Derivative, and novel methyl-methacrylate Derivative were significantly greater than octyl-Cyanoacrylate. When bone sections were fixed with resorbable plates and adhesives, shear bond strength was significantly greater for N-butyl-Cyanoacrylate than plate and screws, while the bond strengths of other adhesives were comparable with the plate and screws. N-Butyl Cyanoacrylate was shown to have the greatest potential for fixation of fractured bone in craniofacial surgical applications.

Dean M Toriumi - One of the best experts on this subject based on the ideXlab platform.

  • use of octyl 2 Cyanoacrylate for skin closure in facial plastic surgery
    Plastic and Reconstructive Surgery, 1998
    Co-Authors: Dean M Toriumi, Kevin Ogrady, Devang P Desai, Amita Bagal
    Abstract:

    Octyl-2-Cyanoacrylate is a long carbon chain Cyanoacrylate Derivative that is stronger and more pliable than its shorter chain Derivatives. One hundred and eleven patients underwent elective surgical procedures by the same surgeon using either octyl-2-Cyanoacrylate or sutures for skin closure at the

  • The current status of Cyanoacrylate and fibrin tissue adhesives.
    Journal of long-term effects of medical implants, 1992
    Co-Authors: Michael Forseth, Kevin O'grady, Dean M Toriumi
    Abstract:

    Surgical tissue adhesives could simplify complex surgical procedures by stabilizing tissue surfaces through hemostasis, sealing wounds, and fixating tissue in areas inaccessible to suture placement. The most common surgical tissue adhesives available to the surgeon include the Cyanoacrylate Derivatives and the fibrin tissue adhesives. Butyl-2 Cyanoacrylate (Histoacryl) is a Cyanoacrylate Derivative that is frequently used in Canada and Europe. This adhesive has excellent binding strength for skin closure; however, subcutaneous implantation can result in inflammation and foreign body giant cell reaction. Fibrin tissue adhesives use a fibrin clot as the binding moiety and vary in adhesive strength depending on the fibrinogen concentration of the preparation. Autologous fibrin tissue adhesives are prepared using one of several different methods, which vary in fibrinogen yield and concentration. The currently available autologous fibrin tissue adhesives demonstrate good hemostatic properties with relatively low binding strengths. This article reviews the status of Cyanoacrylate adhesives and the preparation, efficacy, and clinical applications of the fibrin tissue adhesives.

Devang P Desai - One of the best experts on this subject based on the ideXlab platform.

Kevin Ogrady - One of the best experts on this subject based on the ideXlab platform.