The Experts below are selected from a list of 195 Experts worldwide ranked by ideXlab platform
Alan G Marshall - One of the best experts on this subject based on the ideXlab platform.
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Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Encyclopedia of Analytical Chemistry, 2006Co-Authors: Alan G Marshall, Christopher L. Hendrickson, George S JacksonAbstract:This review offers an introduction to the principles and generic applications of Fourier transform ion Cyclotron Resonance/mass spectrometry (FTICR/MS), directed to readers with no prior experience with the technique. The fundamental Fourier transform ion Cyclotron Resonance (FTICR) phenomenon is explained from a simplified theoretical treatment of ion behavior in idealized magnetic and electric fields. The effects of trapping voltage, trap size and shape, and other nonidealities are then manifested mainly as perturbations that preserve the idealized ion behavior modified by appropriate numerical correction factors. Topics include: effect of ion mass, charge, magnetic field, and trapping voltage on ion Cyclotron frequency; excitation and detection of ion Cyclotron Resonance (ICR) signals; mass calibration; mass resolving power and mass accuracy; upper mass limit(s); dynamic range; detection limit, strategies for mass and energy selection for multiple mass spectroscopy (MSn); ion axialization, cooling, and remeasurement; and means for guiding externally formed ions into the ion trap. The relationship of FTICR/MS to other types of Fourier transform (FT) spectroscopy and to the Paul (quadrupole) ion trap is described. The article concludes with selected applications, an appendix listing accurate fundamental constants needed for ultrahigh-precision analysis, and an annotated list of selected reviews and primary source publications describing various FTICR/MS techniques and applications in fuller detail.
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Broadband axialization in an ion Cyclotron Resonance ion trap
Journal of Chemical Physics, 1994Co-Authors: Shenheng Guan, Markus C Wahl, Alan G MarshallAbstract:A novel broadband ion axialization method has been developed for Fourier transform ion Cyclotron Resonance mass spectrometry based on Penning trapping of ions. Ions of arbitrary mass‐to‐charge ratio range(s) may be driven to the center of the trap (axialization) by azimuthal quadrupolar irradiation with repeated low‐amplitude stored‐wave‐form inverse Fourier transform excitations in the presence of a buffer gas. We demonstrate highly mass‐selective axialization and subsequent high‐resolution Fourier transform ion Cyclotron Resonance detection of ions spanning a mass‐to‐charge ratio range of 500.
Mark R. Emmett - One of the best experts on this subject based on the ideXlab platform.
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ELECTROSPRAY IONIZATION FOURIER TRANSFORM ION Cyclotron Resonance MASS SPECTROMETRY
Annual review of physical chemistry, 1999Co-Authors: Christopher L. Hendrickson, Mark R. EmmettAbstract:▪ Abstract The basic principles and recent advances in electrospray ionization Fourier transform ion Cyclotron Resonance mass spectrometry are reviewed. A brief history of electrospray ionization is provided, along with a complete technical description of the technique, electrospray ionization variations, and advantages. Next, the fundamental principles of Fourier transform ion Cyclotron Resonance mass spectrometry are covered, including ion Cyclotron motion, ion Cyclotron Resonance excitation, and image current detection. Instrumentation and methods used to couple these techniques are then described. Topics include ion source configuration, ion transport through a strong magnetic field gradient, and ion trapping methods. The article concludes with selected applications that highlight the strengths of electrospray ionization Fourier transform ion Cyclotron Resonance mass spectrometry.
Christopher L. Hendrickson - One of the best experts on this subject based on the ideXlab platform.
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Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Encyclopedia of Analytical Chemistry, 2006Co-Authors: Alan G Marshall, Christopher L. Hendrickson, George S JacksonAbstract:This review offers an introduction to the principles and generic applications of Fourier transform ion Cyclotron Resonance/mass spectrometry (FTICR/MS), directed to readers with no prior experience with the technique. The fundamental Fourier transform ion Cyclotron Resonance (FTICR) phenomenon is explained from a simplified theoretical treatment of ion behavior in idealized magnetic and electric fields. The effects of trapping voltage, trap size and shape, and other nonidealities are then manifested mainly as perturbations that preserve the idealized ion behavior modified by appropriate numerical correction factors. Topics include: effect of ion mass, charge, magnetic field, and trapping voltage on ion Cyclotron frequency; excitation and detection of ion Cyclotron Resonance (ICR) signals; mass calibration; mass resolving power and mass accuracy; upper mass limit(s); dynamic range; detection limit, strategies for mass and energy selection for multiple mass spectroscopy (MSn); ion axialization, cooling, and remeasurement; and means for guiding externally formed ions into the ion trap. The relationship of FTICR/MS to other types of Fourier transform (FT) spectroscopy and to the Paul (quadrupole) ion trap is described. The article concludes with selected applications, an appendix listing accurate fundamental constants needed for ultrahigh-precision analysis, and an annotated list of selected reviews and primary source publications describing various FTICR/MS techniques and applications in fuller detail.
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ELECTROSPRAY IONIZATION FOURIER TRANSFORM ION Cyclotron Resonance MASS SPECTROMETRY
Annual review of physical chemistry, 1999Co-Authors: Christopher L. Hendrickson, Mark R. EmmettAbstract:▪ Abstract The basic principles and recent advances in electrospray ionization Fourier transform ion Cyclotron Resonance mass spectrometry are reviewed. A brief history of electrospray ionization is provided, along with a complete technical description of the technique, electrospray ionization variations, and advantages. Next, the fundamental principles of Fourier transform ion Cyclotron Resonance mass spectrometry are covered, including ion Cyclotron motion, ion Cyclotron Resonance excitation, and image current detection. Instrumentation and methods used to couple these techniques are then described. Topics include ion source configuration, ion transport through a strong magnetic field gradient, and ion trapping methods. The article concludes with selected applications that highlight the strengths of electrospray ionization Fourier transform ion Cyclotron Resonance mass spectrometry.
Shenheng Guan - One of the best experts on this subject based on the ideXlab platform.
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Broadband axialization in an ion Cyclotron Resonance ion trap
Journal of Chemical Physics, 1994Co-Authors: Shenheng Guan, Markus C Wahl, Alan G MarshallAbstract:A novel broadband ion axialization method has been developed for Fourier transform ion Cyclotron Resonance mass spectrometry based on Penning trapping of ions. Ions of arbitrary mass‐to‐charge ratio range(s) may be driven to the center of the trap (axialization) by azimuthal quadrupolar irradiation with repeated low‐amplitude stored‐wave‐form inverse Fourier transform excitations in the presence of a buffer gas. We demonstrate highly mass‐selective axialization and subsequent high‐resolution Fourier transform ion Cyclotron Resonance detection of ions spanning a mass‐to‐charge ratio range of 500.
Markus C Wahl - One of the best experts on this subject based on the ideXlab platform.
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Broadband axialization in an ion Cyclotron Resonance ion trap
Journal of Chemical Physics, 1994Co-Authors: Shenheng Guan, Markus C Wahl, Alan G MarshallAbstract:A novel broadband ion axialization method has been developed for Fourier transform ion Cyclotron Resonance mass spectrometry based on Penning trapping of ions. Ions of arbitrary mass‐to‐charge ratio range(s) may be driven to the center of the trap (axialization) by azimuthal quadrupolar irradiation with repeated low‐amplitude stored‐wave‐form inverse Fourier transform excitations in the presence of a buffer gas. We demonstrate highly mass‐selective axialization and subsequent high‐resolution Fourier transform ion Cyclotron Resonance detection of ions spanning a mass‐to‐charge ratio range of 500.
