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Xinmiao Liang - One of the best experts on this subject based on the ideXlab platform.
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selective separation of flavonoid glycosides in Dalbergia odorifera by matrix solid phase dispersion using titania
IEEE Journal of Solid-state Circuits, 2011Co-Authors: Hui Shi, Tu Liang, Jiatao Feng, Yu Jin, Xinmiao LiangAbstract:Selective separation of flavonoid glycosides in Dalbergia odorifera by matrix solid-phase dispersion using titania
Nguyen Manh Cuong - One of the best experts on this subject based on the ideXlab platform.
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FURTHER STUDY ON CHEMICAL CONSTITUENTS FROM THE HEARTWOOD OF Dalbergia TON
Vietnam Journal of Science and Technology, 2018Co-Authors: To Dao Cuong, Ngu Truong Nhan, Nguyen Phuong Dai Nguyen, Pham Ngoc Khanh, Tran Thu Huong, Nguyen Manh CuongAbstract:From the methanol extract of the heartwood of Dalbergia tonkinensis Prain collected in Buon Ma Thuot city, DakLak province, five flavonoids, liquiritigenin (1), 7,3',5'-trihydroxyflavanone (2), sativanone (3), 3'-O-methylviolanone (4) and sulfuretin (5) were isolated. The chemical structures of isolated compounds were determined by the interpretation of NMR spectral data as well as comparison with data from the literature. This study marks that 7,3',5'-trihydroxyflavanone (2) was isolated from the genus Dalbergia for the first time.
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new records of potent in vitro antidiabetic properties of Dalbergia tonkinensis heartwood and the bioactivity guided isolation of active compounds
Molecules, 2018Co-Authors: Van Bon Nguyen, Sanlang Wang, Ngu Truong Nhan, Thi Thanh Hanh Nguyen, Nguyen Phuong Dai Nguyen, Do Huu Nghi, Nguyen Manh CuongAbstract:Alpha-glucosidase inhibitory activity has been commonly used for the evaluation of antidiabetic property in vitro. The aim of this study is to investigate and characterize Dalbergia tonkinensis as a potential source of antidiabetic compounds. The screening of the active parts used, such as trunk bark, heartwood, and the leaves of Dalbergia tonkinensis indicated that all these extracted parts used with methanol demonstrated potent α-glucosidase inhibitory activity. The in vitro antidiabetic property of Dalbergia tonkinensis was notably recorded for the first time and showed activity (EC50 = 0.17–0.78 mg/mL) comparable to those of reported potent herbal extracts (EC50 = 0.25–4.0 mg/mL) and higher activity than that of acarbose, a commercial antidiabetic drug (EC50 = 1.21 mg/mL). The stability tests revealed that the heartwood of Dalbergia tonkinensis extract (HDT) possesses high pH stability with relative activity in the range of 80–98%. Further bioassay-guided purification led to the isolation of 2 active compounds identified as sativanone and formononetin from the ethyl acetate fraction and water fraction of HDT, respectively. These α-glucosidase inhibitors (aGIs) show promising inhibition against various types of α-glucosidases. Remarkably, these inhibitors were determined as new mammalian aGIs, showing good effect on rat α-glucosidase. The results suggest that Dalbergia tonkinensis is a potent source of aGIs and suggest promise in being developed as functional food with antidiabetic efficacy. The results of this study also enrich our knowledge concerning current biological activity and constituents of Dalbergia tonkinensis species.
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Antimicrobial Activity of the Constituents of Dalbergia tonkinensis and Structural-Bioactive Highlights
Natural Product Communications, 2018Co-Authors: Masataka Oda, Nguyen Manh Cuong, Naoki Hayashi, Daiki Yamaguchi, Yu Kawagishi, Fumi Takahashi, Kenichi Harada, Yoshiyasu FukuyamaAbstract:The vulnerable plant Dalbergia tonkinensis Prain, is a rare species, native to Vietnam. Phytochemical investigations and biological evaluations of this species are quite limited. Antimicrobial scre...
Van Bon Nguyen - One of the best experts on this subject based on the ideXlab platform.
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new records of potent in vitro antidiabetic properties of Dalbergia tonkinensis heartwood and the bioactivity guided isolation of active compounds
Molecules, 2018Co-Authors: Van Bon Nguyen, Sanlang Wang, Ngu Truong Nhan, Thi Thanh Hanh Nguyen, Nguyen Phuong Dai Nguyen, Do Huu Nghi, Nguyen Manh CuongAbstract:Alpha-glucosidase inhibitory activity has been commonly used for the evaluation of antidiabetic property in vitro. The aim of this study is to investigate and characterize Dalbergia tonkinensis as a potential source of antidiabetic compounds. The screening of the active parts used, such as trunk bark, heartwood, and the leaves of Dalbergia tonkinensis indicated that all these extracted parts used with methanol demonstrated potent α-glucosidase inhibitory activity. The in vitro antidiabetic property of Dalbergia tonkinensis was notably recorded for the first time and showed activity (EC50 = 0.17–0.78 mg/mL) comparable to those of reported potent herbal extracts (EC50 = 0.25–4.0 mg/mL) and higher activity than that of acarbose, a commercial antidiabetic drug (EC50 = 1.21 mg/mL). The stability tests revealed that the heartwood of Dalbergia tonkinensis extract (HDT) possesses high pH stability with relative activity in the range of 80–98%. Further bioassay-guided purification led to the isolation of 2 active compounds identified as sativanone and formononetin from the ethyl acetate fraction and water fraction of HDT, respectively. These α-glucosidase inhibitors (aGIs) show promising inhibition against various types of α-glucosidases. Remarkably, these inhibitors were determined as new mammalian aGIs, showing good effect on rat α-glucosidase. The results suggest that Dalbergia tonkinensis is a potent source of aGIs and suggest promise in being developed as functional food with antidiabetic efficacy. The results of this study also enrich our knowledge concerning current biological activity and constituents of Dalbergia tonkinensis species.
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New records of potent in-vitro antidiabetic properties of Dalbergia tonkinensis heartwood and the bioactivity-guided isolation of active compounds
MDPI, 2018Co-Authors: Van Bon NguyenAbstract:[[abstract]]Alpha-glucosidase inhibitory activity has been commonly used for the evaluation of antidiabetic property in vitro. The aim of this study is to investigate and characterize Dalbergia tonkinensis as a potential source of antidiabetic compounds. The screening of the active parts used, such as trunk bark, heartwood, and the leaves of Dalbergia tonkinensis indicated that all these extracted parts used with methanol demonstrated potent α-glucosidase inhibitory activity. The in vitro antidiabetic property of Dalbergia tonkinensis was notably recorded for the first time and showed activity (EC50 = 0.17–0.78 mg/mL) comparable to those of reported potent herbal extracts (EC50 = 0.25–4.0 mg/mL) and higher activity than that of acarbose, a commercial antidiabetic drug (EC50 = 1.21 mg/mL). The stability tests revealed that the heartwood of Dalbergia tonkinensis extract (HDT) possesses high pH stability with relative activity in the range of 80–98%. Further bioassay-guided purification led to the isolation of 2 active compounds identified as sativanone and formononetin from the ethyl acetate fraction and water fraction of HDT, respectively. These α-glucosidase inhibitors (aGIs) show promising inhibition against various types of α-glucosidases. Remarkably, these inhibitors were determined as new mammalian aGIs, showing good effect on rat α-glucosidase. The results suggest that Dalbergia tonkinensis is a potent source of aGIs and suggest promise in being developed as functional food with antidiabetic efficacy. The results of this study also enrich our knowledge concerning current biological activity and constituents of Dalbergia tonkinensis species.[[sponsorship]]科技部[[notice]]補正完
Alex Widmer - One of the best experts on this subject based on the ideXlab platform.
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dna barcoding of malagasy rosewoods towards a molecular identification of cites listed Dalbergia species
PLOS ONE, 2016Co-Authors: Sonja Hassold, Porter P Lowry, Martin R Bauert, Annick Razafintsalama, Lolona Ramamonjisoa, Alex WidmerAbstract:Illegal selective logging of tropical timber is of increasing concern worldwide. Madagascar is a biodiversity hotspot and home to some of the world’s most sought after tropical timber species. Malagasy rosewoods belong to the genus Dalbergia (Fabaceae), which is highly diverse and has a pantropical distribution, but these timber species are among the most threatened as a consequence of intensive illegal selective logging and deforestation. Reliable identification of Dalbergia species from Madagascar is important for law enforcement but is almost impossible without fertile plant material, which is often unavailable during forest inventories or when attempting to identify logged trees of cut wood. DNA barcoding has been promoted as a promising tool for species identification in such cases. In this study we tested whether DNA barcoding with partial sequences of three plastid markers (matK, rbcL and trnL (UAA)) can distinguish between Dalbergia from Madagascar and from other areas of its distributional range, and whether Malagasy species can be distinguished from one another. Phylogenetic analyses revealed that the Malagasy Dalbergia species studied form two monophyletic groups, each containing two subgroups, only one of which corresponds to a single species. We characterized diagnostic polymorphisms in the three DNA barcoding markers that allow rapid discrimination between Dalbergia from Madagascar and from other areas of its distribution range. Species identification success based on individual barcoding markers or combinations was poor, whereas subgroup identification success was much higher (up to 98%), revealing both the value and limitations of a DNA barcoding approach for the identification of closely related Malagasy rosewoods.
Han Jing - One of the best experts on this subject based on the ideXlab platform.
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Preparation of solid lipid nanoparticles containing volatile oil of Lignum Dalbergia odoriferae
Chinese Traditional Patent Medicine, 2004Co-Authors: Han JingAbstract:AIM: To delevop new drug delivery system for volatile oil of lignum Dalbergia odoriferae and to improve its effect. METHODS: Solid-lipid-nanopaticals were prepared by hot-dispersiom technique and treated further by sonication; the contents of dispersion and entrapment efficiency of nanoparticles were determined by HPLC. RESULTS: Solid lipid nanoparticles containing volatile oil of lignum Dalbergia odoriferae was spherelike; The partical size was 40.0nm; the content of dispersion was 72.1%; entrapment efficiency of nanoparticles was 91.27%. CONCLUSION: Solid-lipid-nanopatical may be a suitable drug delivery system for volatile oil of lignum Dalbergia odoriferae.
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Preparation of solid lipid nanoparticles containing the volatile oil of Lignum Dalbergia odoriferae
Journal of Shenyang Pharmaceutical University, 2004Co-Authors: Han JingAbstract:Objective To prepare solid lipid nanoparticals containing volatile oil of Lignum Dalbergia odoriferae by the high pressure homoenizer mothod and hot-dispersion technique respectively.Method The main factor affecting solid lipid nanopaticals containing volatile oil of Lignum Dalbergia odoriferae quality in the preparation technics was researched by the single factor exploration and orthogonal design.The satisfactory formulation was selected.Results The results revealing the nanoparticles were spherelike with the mean size of 40.0 nm and 34.5 nm,the content of dispersion was 72.1% and 71.54%.Entrapment efficiency of nanoparticles was 91.27% and 92.36%.Conclusion The hot-dispersion technique on the preparation of solid lipid nanoparticles containning volatile oil of Lignum Dalbergia odoriferae has great practical use.
