The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform
Li Jie - One of the best experts on this subject based on the ideXlab platform.
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A Case of Bulous Mastocytosis
The Chinese Journal of Dermatovenereology, 2010Co-Authors: Li JieAbstract:An 18-month-old girl with blisters and bulla appeared on her head and trunk for about one year. Flushed and the wheal-like skin lesions developed before blisters and bulla appeared. Nikolsky's Sign was absent and Dariers Sign was present. Histopathologic examination showed subepidermal bullae with a dermal aggregation of inflammatory cells. Giemsa staining proved that it was bullous mastocytosis.
Lin Lin - One of the best experts on this subject based on the ideXlab platform.
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Tranilast therapy for generalized cutaneous mastocytosis: a case report
Journal of Clinical Dermatology, 2005Co-Authors: Lin LinAbstract:Here is reported a case of generalized cutaneous mastocytosis treated with tranilast. A 6-year-old boy had papules and maculopapular eruption with scattered nodule and keloid-like lesions on the face, trunk and extremities. The lesions were brown or dark brown in color, bean-sized and elevated with round, oval or irregular appearance. Dariers Sign was positive. Histopathological examination revealed hyperkeratosis accompanied by parakeratosis in the epidermis, dense mast cells and eosinophils infiltrates in the superficial and middle dermis and periadnexal regions, which suggested cutaneous mastocytosis. The patient was treated with oral tranilast alone for 110 days. All the skin lesions subsided with hyperpigmented spots left. Side effects were not noticed during the medication. No recurrence was found within 6-month follow-up.
