The Experts below are selected from a list of 4137 Experts worldwide ranked by ideXlab platform
David J Merritt - One of the best experts on this subject based on the ideXlab platform.
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dorsal longitudinal stretch receptor of drosophila melanogaster larva fine structure and maturation
Arthropod Structure & Development, 2007Co-Authors: Spela Schrader, David J MerrittAbstract:Insects possess two types of sensory Neurons: ciliated type I sensory Neurons that innervate external sensory organs and chordotonal organs, and type II sensory Neurons that form a subepidermal plexus or innervate stretch receptors. Among stretch receptors, a dorsel longitudinal stretch receptor is highly conserved in insects, being found in all insect orders investigated. Here we describe the topology and anatomical structure of this receptor in the fruit fly embryo and larva using transmission electron microscopy and single cell staining for fluorescence microscopy. The receptor is composed of the dorsal bipolar Dendrite Neuron, which arises from an archetypal cell lineage, its sister glial cell and the peripheral glial cell accompanying the nerve. The Neuron is situated among the muscles in the dorsal body wall on the intersegmental nerve. Its two Dendrites stretch the length of the segment to the segmental folds. The Neuron is wrapped by both glial cells and surrounded by a common basal lamina, which fans out at the dendritic tips to attach them to the epidermal cells at the segmental borders.
Yuh Nung Jan - One of the best experts on this subject based on the ideXlab platform.
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hamlet a binary genetic switch between single and multiple Dendrite Neuron morphology
Science, 2002Co-Authors: Adrian W Moore, Lily Yeh Jan, Yuh Nung JanAbstract:The dendritic morphology of Neurons determines the number and type of inputs they receive. In the Drosophila peripheral nervous system (PNS), the external sensory (ES) Neurons have a single nonbranched Dendrite, whereas the lineally related multidendritic (MD) Neurons have extensively branched dendritic arbors. We report that hamlet is a binary genetic switch between these contrasting morphological types. In hamlet mutants, ES Neurons are converted to an MD fate, whereas ectopic hamlet expression in MD precursors results in transformation of MD Neurons into ES Neurons. Moreover, hamlet expression induced in MD Neurons undergoing Dendrite outgrowth drastically reduces arbor branching.
Spela Schrader - One of the best experts on this subject based on the ideXlab platform.
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dorsal longitudinal stretch receptor of drosophila melanogaster larva fine structure and maturation
Arthropod Structure & Development, 2007Co-Authors: Spela Schrader, David J MerrittAbstract:Insects possess two types of sensory Neurons: ciliated type I sensory Neurons that innervate external sensory organs and chordotonal organs, and type II sensory Neurons that form a subepidermal plexus or innervate stretch receptors. Among stretch receptors, a dorsel longitudinal stretch receptor is highly conserved in insects, being found in all insect orders investigated. Here we describe the topology and anatomical structure of this receptor in the fruit fly embryo and larva using transmission electron microscopy and single cell staining for fluorescence microscopy. The receptor is composed of the dorsal bipolar Dendrite Neuron, which arises from an archetypal cell lineage, its sister glial cell and the peripheral glial cell accompanying the nerve. The Neuron is situated among the muscles in the dorsal body wall on the intersegmental nerve. Its two Dendrites stretch the length of the segment to the segmental folds. The Neuron is wrapped by both glial cells and surrounded by a common basal lamina, which fans out at the dendritic tips to attach them to the epidermal cells at the segmental borders.
Adrian W Moore - One of the best experts on this subject based on the ideXlab platform.
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hamlet a binary genetic switch between single and multiple Dendrite Neuron morphology
Science, 2002Co-Authors: Adrian W Moore, Lily Yeh Jan, Yuh Nung JanAbstract:The dendritic morphology of Neurons determines the number and type of inputs they receive. In the Drosophila peripheral nervous system (PNS), the external sensory (ES) Neurons have a single nonbranched Dendrite, whereas the lineally related multidendritic (MD) Neurons have extensively branched dendritic arbors. We report that hamlet is a binary genetic switch between these contrasting morphological types. In hamlet mutants, ES Neurons are converted to an MD fate, whereas ectopic hamlet expression in MD precursors results in transformation of MD Neurons into ES Neurons. Moreover, hamlet expression induced in MD Neurons undergoing Dendrite outgrowth drastically reduces arbor branching.
Lily Yeh Jan - One of the best experts on this subject based on the ideXlab platform.
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hamlet a binary genetic switch between single and multiple Dendrite Neuron morphology
Science, 2002Co-Authors: Adrian W Moore, Lily Yeh Jan, Yuh Nung JanAbstract:The dendritic morphology of Neurons determines the number and type of inputs they receive. In the Drosophila peripheral nervous system (PNS), the external sensory (ES) Neurons have a single nonbranched Dendrite, whereas the lineally related multidendritic (MD) Neurons have extensively branched dendritic arbors. We report that hamlet is a binary genetic switch between these contrasting morphological types. In hamlet mutants, ES Neurons are converted to an MD fate, whereas ectopic hamlet expression in MD precursors results in transformation of MD Neurons into ES Neurons. Moreover, hamlet expression induced in MD Neurons undergoing Dendrite outgrowth drastically reduces arbor branching.